Effect of buffer media composition on the solubility and effective permeability coefficient of ibuprofen

International Journal of Pharmaceutics

Volumn 253, Issue 1-2, 2003, Pages 49-59

  Levis, Karl A ^a   Lane, Majella E ^a   Corrigan, Owen I ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Buffer capacity; Buffers; Ibuprofen; Permeability coefficient; Solubility

Indexed keywords

ACETIC ACID; BICARBONATE; BUFFER; CITRIC ACID; DISODIUM HYDROGEN PHOSPHATE; GLUCOSE; IBUPROFEN; MAGNESIUM SULFATE; PHOSPHATIDYLCHOLINE; POTASSIUM CHLORIDE; POTASSIUM DIHYDROGEN PHOSPHATE; SODIUM CHLORIDE; SODIUM DIHYDROGEN PHOSPHATE; SODIUM HYDROXIDE; TAUROCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG CLASSIFICATION; DRUG PENETRATION; DRUG SOLUBILITY; EXPERIMENTAL MODEL; INTERMETHOD COMPARISON; IONIC STRENGTH; IONIZATION; MALE; MICELLE; NONHUMAN; OSMOLARITY; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; ROOM TEMPERATURE; STATISTICAL SIGNIFICANCE; THERMODYNAMICS;

EID: 0037422394     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00645-2     Document Type: Article

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