Identification of degradation products of Ibuprofen arising from oxidative and thermal treatments

Journal of Pharmaceutical and Biomedical Analysis

Volumn 30, Issue 3, 2002, Pages 499-509

  Caviglioli, Gabriele ^a   Valeria, Posocco ^a   Brunella, Parodi ^a   Sergio, Cafaggi ^a   Attilia, Alzati ^b   Gaetano, Bignardi ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b Pharmatec International Srl   (Italy)

Author keywords

Degradation products; GC MS; HPLC; Ibuprofen; Methyl derivatives; Oxidation

Indexed keywords

1 (4 ISOBUTYLPHENYL) 1 ETHANOL; 1 ISOBUTYL 4 VINYLBENZENE; 2 [4 (1 HYDROXY 2 METHYLPROPYL)PHENYL]PROPANOIC ACID; 4 (1 CARBOXYETHYL)BENZOIC ACID; 4 ETHYLBENZALDEHYDE; 4 ISOBUTYLPHENOL; ALCOHOL DERIVATIVE; BENZALDEHYDE DERIVATIVE; BENZENE DERIVATIVE; BENZOIC ACID DERIVATIVE; HYDRATROPIC ACID; IBUPROFEN; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DEGRADATION; DRUG STRUCTURE; DRUG SYNTHESIS; GAS CHROMATOGRAPHY; HEAT TREATMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL;

DIFFERENTIAL THERMAL ANALYSIS; IBUPROFEN; OXIDATION-REDUCTION;

EID: 0037201760     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(02)00400-4     Document Type: Article

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