Diclofenac sodium incorporated PLGA (50:50) microspheres: Formulation considerations and in vitro/in vivo evaluation

International Journal of Pharmaceutics

Volumn 195, Issue 1-2, 2000, Pages 179-188

  Tuncay M ^a   Calis S ^a   Kas H S ^a   Ercan, M T ^a   Peksoy, I ^a   Hincal, A A ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Diclofenac sodium; Experimental arthritis; Poly (lactide co glycolic acid) microspheres; Scintigraphic imaging; Solvent evaporation method

Indexed keywords

DICLOFENAC; DRUG CARRIER; MICROSPHERE; NONSTEROID ANTIINFLAMMATORY AGENT; POLYGLACTIN; SOLVENT; TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; BIOCOMPATIBILITY; CHRONIC INFLAMMATION; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SCREENING; EVAPORATION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RABBIT; SCINTIGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DICLOFENAC; DRUG CARRIERS; FEMALE; HUMANS; LACTIC ACID; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; RABBITS;

EID: 0342546477     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00394-4     Document Type: Article

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