메뉴 건너뛰기




Volumn 60, Issue 1, 1999, Pages 98-104

Effects of R and S enantiomers and a racemic mixture of carprofen on the production and release of proteoglycan and prostaglandin E2 from equine chondrocytes and cartilage explants

Author keywords

[No Author keywords available]

Indexed keywords

CARPROFEN; GLYCOSAMINOGLYCAN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROTEOGLYCAN; RECOMBINANT INTERLEUKIN 1;

EID: 0032923708     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (36)
  • 1
    • 84985357036 scopus 로고
    • Pharmacokinetics, tolerance and serum thromboxane inhibition of carprofen in the dog
    • McKellar Q, Pearson T, Bogan J, et al. Pharmacokinetics, tolerance and serum thromboxane inhibition of carprofen in the dog. J Small Anim Pract 1990;31:443-448.
    • (1990) J Small Anim Pract , vol.31 , pp. 443-448
    • McKellar, Q.1    Pearson, T.2    Bogan, J.3
  • 2
    • 0029928662 scopus 로고    scopus 로고
    • Evaluation of carprofen in calves using a tissue cage model of inflammation
    • Lees P, Delatour P, Foster AP, et al. Evaluation of carprofen in calves using a tissue cage model of inflammation Br Vet J 1996; 152:199-211.
    • (1996) Br Vet J , vol.152 , pp. 199-211
    • Lees, P.1    Delatour, P.2    Foster, A.P.3
  • 3
    • 0028589349 scopus 로고
    • Stereospecific pharmacodynamics and pharmacokinetics of carprofen in the dog
    • McKellar Q, Delatour P, Lees P Stereospecific pharmacodynamics and pharmacokinetics of carprofen in the dog. J Vet Pharmacol Therap 1994;17:447-454.
    • (1994) J Vet Pharmacol Therap , vol.17 , pp. 447-454
    • McKellar, Q.1    Delatour, P.2    Lees, P.3
  • 5
    • 0029991030 scopus 로고    scopus 로고
    • Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat
    • Taylor P, Delatour P, Landoni FM, et al. Pharmacodynamics and enantioselective pharmacokinetics of carprofen in the cat. Res Vet Sci 1996;60:144-151.
    • (1996) Res Vet Sci , vol.60 , pp. 144-151
    • Taylor, P.1    Delatour, P.2    Landoni, F.M.3
  • 6
    • 0028439857 scopus 로고
    • Pharmacodynamics and pharmacokinetics of carprofen in the horse
    • Lees P, McKellar Q, May S, et al. Pharmacodynamics and pharmacokinetics of carprofen in the horse. Equine Vet J 1994;26: 203-208.
    • (1994) Equine Vet J , vol.26 , pp. 203-208
    • Lees, P.1    McKellar, Q.2    May, S.3
  • 7
    • 0028945151 scopus 로고
    • Randomized controlled trial of the efficacy of carprofen, a nonsteroidal anti-inflammatory drug in the treatment of osteoarthritis in dogs
    • Vasseur PB, Johnson AL, Budsberg SC, et al. Randomized controlled trial of the efficacy of carprofen, a nonsteroidal anti-inflammatory drug in the treatment of osteoarthritis in dogs. J Am Vet Med Assoc 1995;206:807-811.
    • (1995) J Am Vet Med Assoc , vol.206 , pp. 807-811
    • Vasseur, P.B.1    Johnson, A.L.2    Budsberg, S.C.3
  • 8
    • 0028082515 scopus 로고
    • Postoperative analgesic and sedative effects of carprofen and pethidine in dogs
    • Lascelles BD, Butterworth SJ, Waterman AE. Postoperative analgesic and sedative effects of carprofen and pethidine in dogs. Vet Rec 1994;134:187-191.
    • (1994) Vet Rec , vol.134 , pp. 187-191
    • Lascelles, B.D.1    Butterworth, S.J.2    Waterman, A.E.3
  • 9
    • 0029432352 scopus 로고
    • Carprofen as an analgesic for postoperative pain in cats: Dose titration and assessment of efficacy in comparison to pethidine hydrochloride
    • Lascelles B, Cripps P, Mirchandani S, et al. Carprofen as an analgesic for postoperative pain in cats: dose titration and assessment of efficacy in comparison to pethidine hydrochloride. J Small Anim Pract 1995;36:535-541.
    • (1995) J Small Anim Pract , vol.36 , pp. 535-541
    • Lascelles, B.1    Cripps, P.2    Mirchandani, S.3
  • 10
    • 0025246777 scopus 로고
    • Enantiomers in arthritis disorders
    • Williams K. Enantiomers in arthritis disorders. Pharmacol Therap 1990;46:273-295.
    • (1990) Pharmacol Therap , vol.46 , pp. 273-295
    • Williams, K.1
  • 11
    • 0026602064 scopus 로고
    • Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal antiinflammatory drugs
    • Evans A. Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal antiinflammatory drugs. Eur J Clin Pharmacol 1992;42:237-256.
    • (1992) Eur J Clin Pharmacol , vol.42 , pp. 237-256
    • Evans, A.1
  • 12
    • 0029664537 scopus 로고    scopus 로고
    • Chirality and the action of anti-inflammatory drugs
    • Evans AM. Chirality and the action of anti-inflammatory drugs. Br Vet J 1996;152:135-138.
    • (1996) Br Vet J , vol.152 , pp. 135-138
    • Evans, A.M.1
  • 13
    • 0000341401 scopus 로고
    • Pharmacokinetics of carprofen enantiomers in the horse
    • Lees P, Delatour P, Benoit E, et al. Pharmacokinetics of carprofen enantiomers in the horse Acta Vet Scand Suppl 1991;87: 249-251.
    • (1991) Acta Vet Scand Suppl , vol.87 , pp. 249-251
    • Lees, P.1    Delatour, P.2    Benoit, E.3
  • 14
    • 0027971936 scopus 로고
    • Effects of non-steroidal anti-inflammatory drugs on the hyperalgesia to noxious mechanical stimulation induced by the application of a tourniquet to a forelimb of sheep
    • Welsh E, Nolan A. Effects of non-steroidal anti-inflammatory drugs on the hyperalgesia to noxious mechanical stimulation induced by the application of a tourniquet to a forelimb of sheep. Res Vet Sci 1994;57:285-291.
    • (1994) Res Vet Sci , vol.57 , pp. 285-291
    • Welsh, E.1    Nolan, A.2
  • 15
    • 0025619206 scopus 로고
    • Pharmacodynamic evaluation of the peripheral pain inhibition by carprofen and flunixin in the horse
    • Schatzmann U, Gugelmann M, Cranach JV, et al. Pharmacodynamic evaluation of the peripheral pain inhibition by carprofen and flunixin in the horse. Schweiz Arch Tierheilkd 1990;132:497-504.
    • (1990) Schweiz Arch Tierheilkd , vol.132 , pp. 497-504
    • Schatzmann, U.1    Gugelmann, M.2    Cranach, J.V.3
  • 16
    • 0026196555 scopus 로고
    • Interleukin-1-like activity in synovial fluid and sera of horses with arthritis
    • Alwan WH, Carter SD, Dixon JB, et al. Interleukin-1-like activity in synovial fluid and sera of horses with arthritis. Res Vet Sci 1991;51:72-77.
    • (1991) Res Vet Sci , vol.51 , pp. 72-77
    • Alwan, W.H.1    Carter, S.D.2    Dixon, J.B.3
  • 17
    • 0025065527 scopus 로고
    • Identification of interleukin-1 in equine osteoarthritic joint effusions
    • Morris EA, McDonald BS, Webb AC, et al. Identification of interleukin-1 in equine osteoarthritic joint effusions. Am J Vet Res 1990;51:59-64.
    • (1990) Am J Vet Res , vol.51 , pp. 59-64
    • Morris, E.A.1    McDonald, B.S.2    Webb, A.C.3
  • 18
    • 0029298607 scopus 로고
    • Induction of intra-articular tumour necrosis factor during acute inflammatory responses in equine arthritis
    • Billinghurst R, Fretz P, Gordon J. Induction of intra-articular tumour necrosis factor during acute inflammatory responses in equine arthritis. Equine Vet J 1995;27:208-216.
    • (1995) Equine Vet J , vol.27 , pp. 208-216
    • Billinghurst, R.1    Fretz, P.2    Gordon, J.3
  • 19
    • 0024523257 scopus 로고
    • Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis and prostaglandin E2 release from cartilage in organ culture
    • Arner E, Pratta M. Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis and prostaglandin E2 release from cartilage in organ culture. Arth Rheum 1989;32:288-297.
    • (1989) Arth Rheum , vol.32 , pp. 288-297
    • Arner, E.1    Pratta, M.2
  • 20
    • 0028474718 scopus 로고
    • An investigation of the proteoglycan metabolism of mature equine articular cartilage and its regulation by interleukin-1
    • Platt D, Bayliss M. An investigation of the proteoglycan metabolism of mature equine articular cartilage and its regulation by interleukin-1. Equine Vet J 1994;26:297-303.
    • (1994) Equine Vet J , vol.26 , pp. 297-303
    • Platt, D.1    Bayliss, M.2
  • 21
    • 0014957740 scopus 로고
    • Correlations between stiffness and the chemical constituents of cartilage on the human femoral head
    • Kempson G, Muir H, Swanson S, et al. Correlations between stiffness and the chemical constituents of cartilage on the human femoral head. Biochim Biophys Acta 1970;215:70-77.
    • (1970) Biochim Biophys Acta , vol.215 , pp. 70-77
    • Kempson, G.1    Muir, H.2    Swanson, S.3
  • 22
    • 0018090434 scopus 로고
    • A radioimmunoassay for 60keto-prostaglandin F1
    • Salmon J. A radioimmunoassay for 60keto-prostaglandin F1. Prostaglandins 1978;15:383-397.
    • (1978) Prostaglandins , vol.15 , pp. 383-397
    • Salmon, J.1
  • 23
    • 0022552896 scopus 로고
    • Improved quantitation and discrimination of sulphated glycosaminoglycans by the use of dimethylene blue
    • Farndale R, Buttle D, Barrett A. Improved quantitation and discrimination of sulphated glycosaminoglycans by the use of dimethylene blue. Biochim Biophys Acta 1986;883:173-177.
    • (1986) Biochim Biophys Acta , vol.883 , pp. 173-177
    • Farndale, R.1    Buttle, D.2    Barrett, A.3
  • 24
    • 0023739392 scopus 로고
    • Fluorometric assay of DNA in cartilage explants using Hoechst 33258
    • Kim Y-J, Sah R, Doong J-Y, et al. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 1988;174:168-176.
    • (1988) Anal Biochem , vol.174 , pp. 168-176
    • Kim, Y.-J.1    Sah, R.2    Doong, J.-Y.3
  • 25
    • 0025754779 scopus 로고
    • Expression of a mitogen responsive gene encoding prostaglandin synthase is regulate by mRNA splicing
    • Xie W, Chipman J, Robertson D, et al. Expression of a mitogen responsive gene encoding prostaglandin synthase is regulate by mRNA splicing. Proc Natl Acad Sci USA 1991;88:2692-2696.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.2    Robertson, D.3
  • 27
    • 0029915855 scopus 로고    scopus 로고
    • Pharmacodynamics and chiral pharmacokinetics of carprofen in calves
    • Delatour P, Foot R, Foster A, et al. Pharmacodynamics and chiral pharmacokinetics of carprofen in calves. Br Vet J 1996;152:183-198.
    • (1996) Br Vet J , vol.152 , pp. 183-198
    • Delatour, P.1    Foot, R.2    Foster, A.3
  • 28
    • 0030889517 scopus 로고    scopus 로고
    • Effect of carprofen on sulfated glycosaminoglycan metabolism, protein synthesis and prostaglandin release by cultured osteoarthritis canine chondrocytes
    • Benton HP, Vasseur PB, Broderick-Villa GA, et al. Effect of carprofen on sulfated glycosaminoglycan metabolism, protein synthesis and prostaglandin release by cultured osteoarthritis canine chondrocytes. Am J Vet Res 1997;58:286-292.
    • (1997) Am J Vet Res , vol.58 , pp. 286-292
    • Benton, H.P.1    Vasseur, P.B.2    Broderick-Villa, G.A.3
  • 29
    • 0019424142 scopus 로고
    • Ultrafiltration in serum protein binding determinations
    • Whitlam JB, Brown KF. Ultrafiltration in serum protein binding determinations. J Pharm Sci 1981;70:146-150.
    • (1981) J Pharm Sci , vol.70 , pp. 146-150
    • Whitlam, J.B.1    Brown, K.F.2
  • 30
    • 0029077580 scopus 로고
    • Nonsteroidal antiinflammatory drugs: Effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro
    • Smith RL, Kajiyama G, Lane NE. Nonsteroidal antiinflammatory drugs: effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro. J Rheumatol 1995;22:1130-1137.
    • (1995) J Rheumatol , vol.22 , pp. 1130-1137
    • Smith, R.L.1    Kajiyama, G.2    Lane, N.E.3
  • 31
    • 0023906343 scopus 로고
    • Effects of NSAIDs on the metabolism of sulphated glycosaminoglycans in healthy and (post) arthritic murine articular cartilage
    • DeVries B, VanDenBerg W, Vitters E, et al. Effects of NSAIDs on the metabolism of sulphated glycosaminoglycans in healthy and (post) arthritic murine articular cartilage. Drugs Suppl 1 1988;35:24-32.
    • (1988) Drugs Suppl 1 , vol.35 , pp. 24-32
    • DeVries, B.1    Vandenberg, W.2    Vitters, E.3
  • 32
    • 0018909869 scopus 로고
    • Effects of some nonsteroidal antimflammatory drugs on proteoglycan metabolism and organization in canine articular cartilage
    • Palmoski M, Brandt K. Effects of some nonsteroidal antimflammatory drugs on proteoglycan metabolism and organization in canine articular cartilage Arth Rheum 1980;23:1010-1020.
    • (1980) Arth Rheum , vol.23 , pp. 1010-1020
    • Palmoski, M.1    Brandt, K.2
  • 33
    • 0017314575 scopus 로고
    • Osteoarthrosis: Uncertain rationale for antiinflammatory drug therapy
    • McKenzie L, Horsburgh B, Ghosh P, et al. Osteoarthrosis: uncertain rationale for antiinflammatory drug therapy. Lancet 1976;1:908-909
    • (1976) Lancet , vol.1 , pp. 908-909
    • McKenzie, L.1    Horsburgh, B.2    Ghosh, P.3
  • 34
    • 0020534258 scopus 로고
    • Benoxaprofen stimulates proteoglycan synthesis in normal canine knee cartilage in vitro
    • Palmoski M, Brandt K. Benoxaprofen stimulates proteoglycan synthesis in normal canine knee cartilage in vitro. Arth Rheum 1983;26:771-774.
    • (1983) Arth Rheum , vol.26 , pp. 771-774
    • Palmoski, M.1    Brandt, K.2
  • 35
    • 0027740238 scopus 로고
    • The effects of orally administered tiaprofenic acid on the biosynthesis of proteoglycans in ex vivo cartilage cultures from joints of animals with early osteoarthritis
    • Ghosh P, Wells C, Numata Y, et al. The effects of orally administered tiaprofenic acid on the biosynthesis of proteoglycans in ex vivo cartilage cultures from joints of animals with early osteoarthritis. Curr Ther Res 1993;54:703-713.
    • (1993) Curr Ther Res , vol.54 , pp. 703-713
    • Ghosh, P.1    Wells, C.2    Numata, Y.3
  • 36
    • 0020669090 scopus 로고
    • Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients
    • Jalava S, Heizmann P, Kylmamaa T. Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients. Scand J Rheumatol Suppl 1983;48:11-20.
    • (1983) Scand J Rheumatol Suppl , vol.48 , pp. 11-20
    • Jalava, S.1    Heizmann, P.2    Kylmamaa, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.