-
1
-
-
0033920095
-
Disturbing behavior: Neurtotoxic effects in children
-
May M: Disturbing behavior: neurtotoxic effects in children. Environ Health Perspect 2000;108:A262-A267.
-
(2000)
Environ Health Perspect
, vol.108
, pp. A262-A267
-
-
May, M.1
-
3
-
-
84905185084
-
Chemotherapy-induced peripheral neurotoxicity and ototoxicity: New paradigms for translational genomics
-
Travis LB, Fossa SD, Sesso HD, et al.: Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics. J Natl Cancer Inst 2014;106:dju044.
-
(2014)
J Natl Cancer Inst
, vol.106
, pp. dju044
-
-
Travis, L.B.1
Fossa, S.D.2
Sesso, H.D.3
-
4
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
Kola I, Landis J: Can the pharmaceutical industry reduce attrition rates? Nat Rev Drug Discov 2004;3:711-715.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
5
-
-
67650445156
-
Toxicology for the twenty-first century
-
Hartung T: Toxicology for the twenty-first century. Nature 2009;460:208-212.
-
(2009)
Nature
, vol.460
, pp. 208-212
-
-
Hartung, T.1
-
6
-
-
73949115799
-
Relevance of in vitro neurotoxicity testing for regulatory requirements: Challenges to be considered
-
Bal-Price AK, Hogberg HT, Buzanska L, Coecke S: Relevance of in vitro neurotoxicity testing for regulatory requirements: challenges to be considered. Neurotoxicol Teratol 2010;32:36-41.
-
(2010)
Neurotoxicol Teratol
, vol.32
, pp. 36-41
-
-
Bal-Price, A.K.1
Hogberg, H.T.2
Buzanska, L.3
Coecke, S.4
-
7
-
-
77952673694
-
Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis
-
Harrill JA, Freudenrich TM, Machacek DW, Stice SL, Mundy WR: Quantitative assessment of neurite outgrowth in human embryonic stem cell-derived hN2 cells using automated high-content image analysis. Neurotoxicology 2010;31:277-290.
-
(2010)
Neurotoxicology
, vol.31
, pp. 277-290
-
-
Harrill, J.A.1
Freudenrich, T.M.2
Machacek, D.W.3
Stice, S.L.4
Mundy, W.R.5
-
8
-
-
77956230392
-
An imaging assay to analyze primary neurons for cellular neurotoxicity
-
Gotte M, Hofmann G, Michou-Gallani AI, Glickman JF, Wishart W, Gabriel D: An imaging assay to analyze primary neurons for cellular neurotoxicity. J Neurosci Methods 2010;192:7-16.
-
(2010)
J Neurosci Methods
, vol.192
, pp. 7-16
-
-
Gotte, M.1
Hofmann, G.2
Michou-Gallani, A.I.3
Glickman, J.F.4
Wishart, W.5
Gabriel, D.6
-
9
-
-
84878051513
-
Chemical interrogation of the neuronal kinome using a primary cell-based screening assay
-
Al-Ali H, Schurer SC, Lemmon VP, Bixby JL: Chemical interrogation of the neuronal kinome using a primary cell-based screening assay. ACS Chem Biol 2013;8:1027-1036.
-
(2013)
ACS Chem Biol
, vol.8
, pp. 1027-1036
-
-
Al-Ali, H.1
Schurer, S.C.2
Lemmon, V.P.3
Bixby, J.L.4
-
10
-
-
44649176280
-
Developmental neurotoxicity testing in vitro: Models for assessing chemical effects on neurite outgrowth
-
Radio NM, Mundy WR: Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth. Neurotoxicology 2008;29:361-376.
-
(2008)
Neurotoxicology
, vol.29
, pp. 361-376
-
-
Radio, N.M.1
Mundy, W.R.2
-
11
-
-
49249116936
-
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening
-
Radio NM, Breier JM, Shafer TJ, Mundy WR: Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening. Toxicol Sci 2008;105:106-118.
-
(2008)
Toxicol Sci
, vol.105
, pp. 106-118
-
-
Radio, N.M.1
Breier, J.M.2
Shafer, T.J.3
Mundy, W.R.4
-
12
-
-
49249113004
-
Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells
-
Breier JM, Radio NM, Mundy WR, Shafer TJ: Development of a high-throughput screening assay for chemical effects on proliferation and viability of immortalized human neural progenitor cells. Toxicol Sci 2008;105:119-133.
-
(2008)
Toxicol Sci
, vol.105
, pp. 119-133
-
-
Breier, J.M.1
Radio, N.M.2
Mundy, W.R.3
Shafer, T.J.4
-
13
-
-
80052271335
-
Ion channels and ionotropic receptors in human embryonic stem cell derived neural progenitors
-
Young A, Machacek DW, Dhara SK, et al.: Ion channels and ionotropic receptors in human embryonic stem cell derived neural progenitors. Neuroscience 2011;192:793-805.
-
(2011)
Neuroscience
, vol.192
, pp. 793-805
-
-
Young, A.1
Machacek, D.W.2
Dhara, S.K.3
-
14
-
-
52449130309
-
High-content analysis in neuroscience
-
Dragunow M: High-content analysis in neuroscience. Nat Rev Neurosci 2008;9:779-788.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 779-788
-
-
Dragunow, M.1
-
15
-
-
84870357944
-
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons
-
Harrill JA, Robinette BL, Freudenrich T, Mundy WR: Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons. Neurotoxicology 2013;34:61-73.
-
(2013)
Neurotoxicology
, vol.34
, pp. 61-73
-
-
Harrill, J.A.1
Robinette, B.L.2
Freudenrich, T.3
Mundy, W.R.4
-
16
-
-
84890842518
-
Functional screening assays with neurons generated from pluripotent stem cell-derived neural stem cells
-
Efthymiou A, Shaltouki A, Steiner JP, et al.: Functional screening assays with neurons generated from pluripotent stem cell-derived neural stem cells. J Biomol Screen 2014;19:32-43.
-
(2014)
J Biomol Screen
, vol.19
, pp. 32-43
-
-
Efthymiou, A.1
Shaltouki, A.2
Steiner, J.P.3
-
17
-
-
79955611823
-
Chemically defined conditions for human iPSC derivation and culture
-
Chen G, Gulbranson DR, Hou Z, et al.: Chemically defined conditions for human iPSC derivation and culture. Nat Methods 2011;8:424-429.
-
(2011)
Nat Methods
, vol.8
, pp. 424-429
-
-
Chen, G.1
Gulbranson, D.R.2
Hou, Z.3
-
18
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu BY, Weick JP, Yu J, et al.: Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A 2010;107:4335-4340.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
-
19
-
-
79955482429
-
Opportunities for use of human iPS cells in predictive toxicology
-
Anson BD, Kolaja KL, Kamp TJ: Opportunities for use of human iPS cells in predictive toxicology. Clin Pharmacol Ther 2011;89:754-758.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 754-758
-
-
Anson, B.D.1
Kolaja, K.L.2
Kamp, T.J.3
-
20
-
-
84866431713
-
Characterizing human ion channels in induced pluripotent stem cell-derived neurons
-
Haythornthwaite A, Stoelzle S, Hasler A, et al.: Characterizing human ion channels in induced pluripotent stem cell-derived neurons. J Biomol Screen 2012;17:1264-1272.
-
(2012)
J Biomol Screen
, vol.17
, pp. 1264-1272
-
-
Haythornthwaite, A.1
Stoelzle, S.2
Hasler, A.3
-
21
-
-
84864935106
-
Constitutive secretion of tau protein by an unconventional mechanism
-
Chai X, Dage JL, Citron M: Constitutive secretion of tau protein by an unconventional mechanism. Neurobiol Dis 2012;48:356-366.
-
(2012)
Neurobiol Dis
, vol.48
, pp. 356-366
-
-
Chai, X.1
Dage, J.L.2
Citron, M.3
-
22
-
-
84859017992
-
Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection
-
Whitemarsh RC, Strathman MJ, Chase LG, et al.: Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection. Toxicol Sci 2012;126:426-435.
-
(2012)
Toxicol Sci
, vol.126
, pp. 426-435
-
-
Whitemarsh, R.C.1
Strathman, M.J.2
Chase, L.G.3
-
23
-
-
84896711407
-
Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons
-
Dage JL, Colvin EM, Fouillet A, et al.: Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons. Psychopharmacology 2014;231:1105-1124.
-
(2014)
Psychopharmacology
, vol.231
, pp. 1105-1124
-
-
Dage, J.L.1
Colvin, E.M.2
Fouillet, A.3
-
24
-
-
80052487012
-
Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes
-
Guo L, Abrams RM, Babiarz JE, et al.: Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Sci 2011;123:281-289.
-
(2011)
Toxicol Sci
, vol.123
, pp. 281-289
-
-
Guo, L.1
Abrams, R.M.2
Babiarz, J.E.3
-
25
-
-
84896696047
-
High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells
-
Sirenko O, Hesley J, Rusyn I, Cromwell EF: High-content assays for hepatotoxicity using induced pluripotent stem cell-derived cells. Assay Drug Dev Technol 2014;12:43-54.
-
(2014)
Assay Drug Dev Technol
, vol.12
, pp. 43-54
-
-
Sirenko, O.1
Hesley, J.2
Rusyn, I.3
Cromwell, E.F.4
-
26
-
-
84872171503
-
Prevention of beta-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events
-
Xu X, Lei Y, Luo J, et al.: Prevention of beta-amyloid induced toxicity in human iPS cell-derived neurons by inhibition of Cyclin-dependent kinases and associated cell cycle events. Stem Cell Res 2013;10:213-227.
-
(2013)
Stem Cell Res
, vol.10
, pp. 213-227
-
-
Xu, X.1
Lei, Y.2
Luo, J.3
-
27
-
-
79953826088
-
Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells
-
Hu K, Yu J, Suknuntha K, et al.: Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood 2011;117:e109-e119.
-
(2011)
Blood
, vol.117
, pp. e109-e119
-
-
Hu, K.1
Yu, J.2
Suknuntha, K.3
-
29
-
-
0022827447
-
Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2
-
Neve RL, Harris P, Kosik KS, Kurnit DM, Donlon TA: Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2. Brain Res 1986;387:271-280.
-
(1986)
Brain Res
, vol.387
, pp. 271-280
-
-
Neve, R.L.1
Harris, P.2
Kosik, K.S.3
Kurnit, D.M.4
Donlon, T.A.5
-
31
-
-
0142213730
-
The toxicology of mercury-current exposures and clinical manifestations
-
Clarkson TW, Magos L, Myers GJ: The toxicology of mercury-current exposures and clinical manifestations. N Engl J Med 2003;349:1731-1737.
-
(2003)
N Engl J Med
, vol.349
, pp. 1731-1737
-
-
Clarkson, T.W.1
Magos, L.2
Myers, G.J.3
-
32
-
-
79961210983
-
Rotenone induced neurotoxicity in rat brain areas: A histopathological study
-
Swarnkar S, Singh S, Sharma S, Mathur R, Patro IK, Nath C: Rotenone induced neurotoxicity in rat brain areas: a histopathological study. Neurosci Lett 2011;501:123-127.
-
(2011)
Neurosci Lett
, vol.501
, pp. 123-127
-
-
Swarnkar, S.1
Singh, S.2
Sharma, S.3
Mathur, R.4
Patro, I.K.5
Nath, C.6
-
33
-
-
0036470165
-
Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons
-
Gao HM, Hong JS, Zhang W, Liu B: Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci 2002;22:782-790.
-
(2002)
J Neurosci
, vol.22
, pp. 782-790
-
-
Gao, H.M.1
Hong, J.S.2
Zhang, W.3
Liu, B.4
-
34
-
-
0017860210
-
Mitomycin C, vincristine, and bleomycin therapy for advanced cervical cancer
-
Baker LH, Opipari MI, Wilson H, Bottomley R, Coltman CA, Jr. Mitomycin C, vincristine, and bleomycin therapy for advanced cervical cancer. Obstet Gynecol 1978;52:146-150.
-
(1978)
Obstet Gynecol
, vol.52
, pp. 146-150
-
-
Baker, L.H.1
Opipari, M.I.2
Wilson, H.3
Bottomley, R.4
Coltman, C.A.5
-
35
-
-
0028881848
-
Mitochondrial membrane potential monitored by JC-1 dye
-
Reers M, Smiley ST, Mottola-Hartshorn C, Chen A, Lin M, Chen LB. Mitochondrial membrane potential monitored by JC-1 dye. Methods Enzymol 1995;260:406-417.
-
(1995)
Methods Enzymol
, vol.260
, pp. 406-417
-
-
Reers, M.1
Smiley, S.T.2
Mottola-Hartshorn, C.3
Chen, A.4
Lin, M.5
Chen, L.B.6
-
36
-
-
20344374998
-
Successful conversion to rapamycin for calcineurin inhibitor-related neurotoxicity following liver transplantation
-
Forgacs B, Merhav HJ, Lappin J, Mieles L: Successful conversion to rapamycin for calcineurin inhibitor-related neurotoxicity following liver transplantation. Transplant Proc 2005;37:1912-1914.
-
(2005)
Transplant Proc
, vol.37
, pp. 1912-1914
-
-
Forgacs, B.1
Merhav, H.J.2
Lappin, J.3
Mieles, L.4
-
37
-
-
77952756933
-
High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors
-
McNeish J, Roach M, Hambor J, et al.: High-throughput screening in embryonic stem cell-derived neurons identifies potentiators of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate-type glutamate receptors. J Biol Chem 2010;285:17209-17217.
-
(2010)
J Biol Chem
, vol.285
, pp. 17209-17217
-
-
McNeish, J.1
Roach, M.2
Hambor, J.3
-
38
-
-
73649102801
-
Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science
-
Breier JM, Gassmann K, Kayser R, et al.: Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science. Neurotoxicol Teratol 2010;32:4-15.
-
(2010)
Neurotoxicol Teratol
, vol.32
, pp. 4-15
-
-
Breier, J.M.1
Gassmann, K.2
Kayser, R.3
-
39
-
-
84885292635
-
Rotenone induces neuronal death by microglial phagocytosis of neurons
-
Emmrich JV, Hornik TC, Neher JJ, Brown GC: Rotenone induces neuronal death by microglial phagocytosis of neurons. FEBS J 2013;280:5030-5038.
-
(2013)
FEBS J
, vol.280
, pp. 5030-5038
-
-
Emmrich, J.V.1
Hornik, T.C.2
Neher, J.J.3
Brown, G.C.4
-
40
-
-
0028090316
-
Methylmercury induces apoptosis of rat cerebellar neurons in primary culture
-
Kunimoto M: Methylmercury induces apoptosis of rat cerebellar neurons in primary culture. Biochem Biophys Res Commun 1994;204:310-317.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 310-317
-
-
Kunimoto, M.1
-
41
-
-
84901603584
-
Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy
-
Zhang H, Dougherty PM: Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. Anesthesiology 2014;120:1463-1475.
-
(2014)
Anesthesiology
, vol.120
, pp. 1463-1475
-
-
Zhang, H.1
Dougherty, P.M.2
|