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Volumn 280, Issue 20, 2013, Pages 5030-5038

Rotenone induces neuronal death by microglial phagocytosis of neurons

Author keywords

inflammation; microglia; mitochondria; Parkinson's disease; phagoptosis

Indexed keywords

PURINERGIC P2Y6 RECEPTOR; ROTENONE; TUMOR NECROSIS FACTOR ALPHA; VITRONECTIN RECEPTOR;

EID: 84885292635     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12401     Document Type: Conference Paper
Times cited : (72)

References (42)
  • 2
    • 0037402801 scopus 로고    scopus 로고
    • Selective microglial activation in the rat rotenone model of Parkinson's disease
    • Sherer TB, Betarbet R, Kim JH, &, Greenamyre JT, (2003) Selective microglial activation in the rat rotenone model of Parkinson's disease. Neurosci Lett 341, 87-90.
    • (2003) Neurosci Lett , vol.341 , pp. 87-90
    • Sherer, T.B.1    Betarbet, R.2    Kim, J.H.3    Greenamyre, J.T.4
  • 3
    • 33746326513 scopus 로고    scopus 로고
    • Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration
    • Radad K, Rausch WD, &, Gille G, (2006) Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration. Neurochem Int 49, 379-386.
    • (2006) Neurochem Int , vol.49 , pp. 379-386
    • Radad, K.1    Rausch, W.D.2    Gille, G.3
  • 4
    • 34447122557 scopus 로고    scopus 로고
    • Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex i with rotenone
    • Yadava N, &, Nicholls DG, (2007) Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci 27, 7310-7317.
    • (2007) J Neurosci , vol.27 , pp. 7310-7317
    • Yadava, N.1    Nicholls, D.G.2
  • 6
    • 0037104723 scopus 로고    scopus 로고
    • An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage
    • Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, &, Greenamyre JT, (2002) An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage. J Neurosci 22, 7006-7015.
    • (2002) J Neurosci , vol.22 , pp. 7006-7015
    • Sherer, T.B.1    Betarbet, R.2    Stout, A.K.3    Lund, S.4    Baptista, M.5    Panov, A.V.6    Cookson, M.R.7    Greenamyre, J.T.8
  • 7
    • 0036470165 scopus 로고    scopus 로고
    • Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons
    • Gao HM, Hong JS, Zhang W, &, Liu B, (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J Neurosci 22, 782-790.
    • (2002) J Neurosci , vol.22 , pp. 782-790
    • Gao, H.M.1    Hong, J.S.2    Zhang, W.3    Liu, B.4
  • 8
    • 79952368703 scopus 로고    scopus 로고
    • Loss of mitochondrial complex i activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model
    • Choi WS, Palmiter RD, &, Xia Z, (2011) Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. J Cell Biol 192, 873-882.
    • (2011) J Cell Biol , vol.192 , pp. 873-882
    • Choi, W.S.1    Palmiter, R.D.2    Xia, Z.3
  • 10
    • 79960141471 scopus 로고    scopus 로고
    • The immunology of stroke: From mechanisms to translation
    • Iadecola C, &, Anrather J, (2011) The immunology of stroke: from mechanisms to translation. Nat Med 17, 796-808.
    • (2011) Nat Med , vol.17 , pp. 796-808
    • Iadecola, C.1    Anrather, J.2
  • 11
    • 84864322419 scopus 로고    scopus 로고
    • Eaten alive! Cell death by primary phagocytosis: 'Phagoptosis'
    • Brown GC, &, Neher JJ, (2012) Eaten alive! Cell death by primary phagocytosis: 'phagoptosis'. Trends Biochem Sci 37, 325-332.
    • (2012) Trends Biochem Sci , vol.37 , pp. 325-332
    • Brown, G.C.1    Neher, J.J.2
  • 12
    • 79955008182 scopus 로고    scopus 로고
    • Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death
    • Neher JJ, Neniskyte U, Zhao JW, Bal-Price A, Tolkovsky AM, &, Brown GC, (2011) Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death. J Immunol 186, 4973-4983.
    • (2011) J Immunol , vol.186 , pp. 4973-4983
    • Neher, J.J.1    Neniskyte, U.2    Zhao, J.W.3    Bal-Price, A.4    Tolkovsky, A.M.5    Brown, G.C.6
  • 13
    • 81155154302 scopus 로고    scopus 로고
    • Neuronal death induced by nanomolar amyloid beta is mediated by primary phagocytosis of neurons by microglia
    • Neniskyte U, Neher JJ, &, Brown GC, (2011) Neuronal death induced by nanomolar amyloid beta is mediated by primary phagocytosis of neurons by microglia. J Biol Chem 286, 39904-39913.
    • (2011) J Biol Chem , vol.286 , pp. 39904-39913
    • Neniskyte, U.1    Neher, J.J.2    Brown, G.C.3
  • 14
    • 84863141913 scopus 로고    scopus 로고
    • MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation
    • Fricker M, Neher JJ, Zhao JW, Thery C, Tolkovsky AM, &, Brown GC, (2012) MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation. J Neurosci 32, 2657-2666.
    • (2012) J Neurosci , vol.32 , pp. 2657-2666
    • Fricker, M.1    Neher, J.J.2    Zhao, J.W.3    Thery, C.4    Tolkovsky, A.M.5    Brown, G.C.6
  • 16
    • 84862334971 scopus 로고    scopus 로고
    • Primary phagocytosis of neurons by inflamed microglia: Potential roles in neurodegeneration
    • Neher J, Neniskyte U, &, Brown G, (2012) Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration. Front Pharmacol 3, 27.
    • (2012) Front Pharmacol , vol.3 , pp. 27
    • Neher, J.1    Neniskyte, U.2    Brown, G.3
  • 17
    • 79957606041 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Schapira A, &, Jenner P, (2011) Etiology and pathogenesis of Parkinson's disease. Mov Disord 26, 1049-1055.
    • (2011) Mov Disord , vol.26 , pp. 1049-1055
    • Schapira, A.1    Jenner, P.2
  • 18
    • 75949087271 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
    • Tansey M, &, Goldberg M, (2010) Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention. Neurobiol Dis 37, 510-518.
    • (2010) Neurobiol Dis , vol.37 , pp. 510-518
    • Tansey, M.1    Goldberg, M.2
  • 19
    • 51349105921 scopus 로고    scopus 로고
    • Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: Implications for Parkinson's disease
    • Park J, Paik S, Jou I, &, Park S, (2008) Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinson's disease. Glia 56, 1215-1223.
    • (2008) Glia , vol.56 , pp. 1215-1223
    • Park, J.1    Paik, S.2    Jou, I.3    Park, S.4
  • 20
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • Block M, Zecca L, &, Hong J, (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 8, 57-69.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 57-69
    • Block, M.1    Zecca, L.2    Hong, J.3
  • 21
    • 84863666597 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models
    • Xiong N, Long X, Xiong J, Jia M, Chen C, Huang J, Ghoorah D, Kong X, Linz Z, &, Wang T, (2012) Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models. Crit Rev Toxicol 42, 613-632.
    • (2012) Crit Rev Toxicol , vol.42 , pp. 613-632
    • Xiong, N.1    Long, X.2    Xiong, J.3    Jia, M.4    Chen, C.5    Huang, J.6    Ghoorah, D.7    Kong, X.8    Linz, Z.9    Wang, T.10
  • 23
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Budd SL, &, Nicholls DG, (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67, 2282-2291.
    • (1996) J Neurochem , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 24
    • 0031753043 scopus 로고    scopus 로고
    • 1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis
    • Leist M, Volbracht C, Fava E, &, Nicotera P, (1998) 1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis. Mol Pharmacol 54, 789-801.
    • (1998) Mol Pharmacol , vol.54 , pp. 789-801
    • Leist, M.1    Volbracht, C.2    Fava, E.3    Nicotera, P.4
  • 25
    • 0038044029 scopus 로고    scopus 로고
    • Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons
    • Gao HM, Liu B, &, Hong J-S, (2003) Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. J Neurosci 23, 6181-6187.
    • (2003) J Neurosci , vol.23 , pp. 6181-6187
    • Gao, H.M.1    Liu, B.2    Hong, J.-S.3
  • 26
    • 0021987350 scopus 로고
    • Modulation of human natural killer cell function by l -leucine methyl ester: Monocyte-dependent depletion from human peripheral blood mononuclear cells
    • Thiele D, &, Lipsky P, (1985) Modulation of human natural killer cell function by l -leucine methyl ester: monocyte-dependent depletion from human peripheral blood mononuclear cells. J Immunol 134, 786-793.
    • (1985) J Immunol , vol.134 , pp. 786-793
    • Thiele, D.1    Lipsky, P.2
  • 27
    • 84885294996 scopus 로고    scopus 로고
    • Elimination of cell types from mixed neural cell cultures
    • 3rd edn (Fedoroff S. & Richardson A. eds), Humana Press, Totowa, NJ
    • Devon RM, (2000) Elimination of cell types from mixed neural cell cultures. In Protocols for Neural Cell Culture, 3rd edn (, Fedoroff S, &, Richardson A, eds), pp. 325-332. Humana Press, Totowa, NJ.
    • (2000) Protocols for Neural Cell Culture , pp. 325-332
    • Devon, R.M.1
  • 29
    • 84862487723 scopus 로고    scopus 로고
    • Involvement of 5-lipoxygenase/cysteinyl leukotriene receptor 1 in rotenone- and MPP+-induced BV2 microglial activation
    • Wang Y, Zhang X, Li C, Zhao J, Wei E, &, Zhang L, (2012) Involvement of 5-lipoxygenase/cysteinyl leukotriene receptor 1 in rotenone- and MPP+-induced BV2 microglial activation. Mol Neurodegener 7 (Suppl 1), S24.
    • (2012) Mol Neurodegener , vol.7 , Issue.SUPPL. 1
    • Wang, Y.1    Zhang, X.2    Li, C.3    Zhao, J.4    Wei, E.5    Zhang, L.6
  • 30
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: The find-me and eat-me signaling pathways
    • Ravichandran KS, (2011) Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 35, 445-455.
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 33
    • 0029778085 scopus 로고    scopus 로고
    • Structural and functional aspects of RGD-containing cyclic pentapeptides as highly potent and selective integrin αvβ3 antagonists
    • Haubner R, Gratias R, Diefenbach B, Goodman SL, Jonczyk A, &, Kessler H, (1996) Structural and functional aspects of RGD-containing cyclic pentapeptides as highly potent and selective integrin αvβ3 antagonists. J Am Chem Soc 118, 7461-7472.
    • (1996) J Am Chem Soc , vol.118 , pp. 7461-7472
    • Haubner, R.1    Gratias, R.2    Diefenbach, B.3    Goodman, S.L.4    Jonczyk, A.5    Kessler, H.6
  • 35
    • 36248951667 scopus 로고    scopus 로고
    • Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation
    • Zhou F, Wu JY, Sun XL, Yao HH, Ding JH, &, Hu G, (2007) Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation. Neuropsychopharmacology 32, 2570-2580.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2570-2580
    • Zhou, F.1    Wu, J.Y.2    Sun, X.L.3    Yao, H.H.4    Ding, J.H.5    Hu, G.6
  • 36
    • 34547138164 scopus 로고    scopus 로고
    • Regulated externalization of phosphatidylserine at the cell surface: Implications for apoptosis
    • Balasubramanian K, Mirnikjoo B, &, Schroit AJ, (2007) Regulated externalization of phosphatidylserine at the cell surface: implications for apoptosis. J Biol Chem 282, 18357-18364.
    • (2007) J Biol Chem , vol.282 , pp. 18357-18364
    • Balasubramanian, K.1    Mirnikjoo, B.2    Schroit, A.J.3
  • 37
    • 34247235049 scopus 로고    scopus 로고
    • Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: Implications for the resolution of inflammation
    • Tyurina YY, Basova LV, Konduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, et al,. (2007) Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J Biol Chem 282, 8498-8509.
    • (2007) J Biol Chem , vol.282 , pp. 8498-8509
    • Tyurina, Y.Y.1    Basova, L.V.2    Konduru, N.V.3    Tyurin, V.A.4    Potapovich, A.I.5    Cai, P.6    Bayir, H.7    Stoyanovsky, D.8    Pitt, B.R.9    Shvedova, A.A.10
  • 38
    • 54449089025 scopus 로고    scopus 로고
    • Mitochondrial complex i inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat
    • Choi WS, Kruse SE, Palmiter RD, &, Xia Z, (2008) Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proc Natl Acad Sci USA 105, 15136-15141.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15136-15141
    • Choi, W.S.1    Kruse, S.E.2    Palmiter, R.D.3    Xia, Z.4
  • 39
    • 0023879208 scopus 로고
    • A cytostatic drug (taxol) which does not inhibit monocyte phagocytosis
    • Athlin L, Domellöf L, &, Norberg B, (1988) A cytostatic drug (taxol) which does not inhibit monocyte phagocytosis. Med Oncol Tumor Pharmacother 5, 135-138.
    • (1988) Med Oncol Tumor Pharmacother , vol.5 , pp. 135-138
    • Athlin, L.1    Domellöf, L.2    Norberg, B.3
  • 41
    • 28244472094 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation
    • Kinsner A, Pilotto V, Deininger S, Brown GC, Coecke S, Hartung T, &, Bal-Price A, (2005) Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation. J Neurochem 95, 1132-1143.
    • (2005) J Neurochem , vol.95 , pp. 1132-1143
    • Kinsner, A.1    Pilotto, V.2    Deininger, S.3    Brown, G.C.4    Coecke, S.5    Hartung, T.6    Bal-Price, A.7
  • 42
    • 0034307759 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
    • Ward M, Rego A, Frenguelli B, &, Nicholls D, (2000) Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 20, 7208-7219.
    • (2000) J Neurosci , vol.20 , pp. 7208-7219
    • Ward, M.1    Rego, A.2    Frenguelli, B.3    Nicholls, D.4


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