메뉴 건너뛰기




Volumn 136, Issue , 2014, Pages 31-38

Obesity induces neuroinflammation mediated by altered expression of the renin-angiotensin system in mouse forebrain nuclei

Author keywords

Angiotensin type 1 receptor; Astrocyte; High fat diet; Microglia; Paraventricular nucleus

Indexed keywords

ANGIOTENSIN 1A RECEPTOR; COMPLEMENTARY DNA; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; ANGIOTENSIN II; APOPTOSIS REGULATORY PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CALCIUM BINDING PROTEIN; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; MEMBRANE PROTEIN; REPRESSOR PROTEIN; SIM1 PROTEIN, MOUSE; VASN PROTEIN, MOUSE;

EID: 84917743669     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2014.01.016     Document Type: Article
Times cited : (55)

References (61)
  • 1
    • 0023204243 scopus 로고
    • Incidence and precursors of hypertension in young adults: the Framingham Offspring Study
    • Garrison R.J., Kannel W.B., Stokes J., Castelli W.P. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987, 16(2):235-251.
    • (1987) Prev Med , vol.16 , Issue.2 , pp. 235-251
    • Garrison, R.J.1    Kannel, W.B.2    Stokes, J.3    Castelli, W.P.4
  • 2
    • 67649855154 scopus 로고    scopus 로고
    • Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype
    • Timpson N.J., Harbord R., Davey Smith G., Zacho J., Tybjaerg-Hansen A., Nordestgaard B.G. Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype. Hypertension 2009, 54(1):84-90.
    • (2009) Hypertension , vol.54 , Issue.1 , pp. 84-90
    • Timpson, N.J.1    Harbord, R.2    Davey Smith, G.3    Zacho, J.4    Tybjaerg-Hansen, A.5    Nordestgaard, B.G.6
  • 4
    • 69649097826 scopus 로고    scopus 로고
    • Obesity dynamics and cardiovascular risk factor stability in obese adolescents
    • Weiss R., Shaw M., Savoye M., Caprio S. Obesity dynamics and cardiovascular risk factor stability in obese adolescents. Pediatr Diabetes 2009, 10(6):360-367.
    • (2009) Pediatr Diabetes , vol.10 , Issue.6 , pp. 360-367
    • Weiss, R.1    Shaw, M.2    Savoye, M.3    Caprio, S.4
  • 5
    • 0025589490 scopus 로고
    • Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study
    • Cassano P.A., Segal M.R., Vokonas P.S., Weiss S.T. Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study. Ann Epidemiol 1990, 1(1):33-48.
    • (1990) Ann Epidemiol , vol.1 , Issue.1 , pp. 33-48
    • Cassano, P.A.1    Segal, M.R.2    Vokonas, P.S.3    Weiss, S.T.4
  • 6
    • 84865811092 scopus 로고    scopus 로고
    • Rapid onset of renal sympathetic nerve activation in rabbits fed a high-fat diet
    • Armitage J.A., Burke S.L., Prior L.J., Barzel B., Eikelis N., Lim K., et al. Rapid onset of renal sympathetic nerve activation in rabbits fed a high-fat diet. Hypertension 2012, 60(1):163-171.
    • (2012) Hypertension , vol.60 , Issue.1 , pp. 163-171
    • Armitage, J.A.1    Burke, S.L.2    Prior, L.J.3    Barzel, B.4    Eikelis, N.5    Lim, K.6
  • 8
    • 0031967987 scopus 로고    scopus 로고
    • Angiotensinogen levels and obesity in four black populations. ICSHIB Investigators
    • Cooper R., Forrester T., Ogunbiyi O., Muffinda J. Angiotensinogen levels and obesity in four black populations. ICSHIB Investigators. J Hypertens 1998, 16(5):571-575.
    • (1998) J Hypertens , vol.16 , Issue.5 , pp. 571-575
    • Cooper, R.1    Forrester, T.2    Ogunbiyi, O.3    Muffinda, J.4
  • 11
    • 84859499507 scopus 로고    scopus 로고
    • T lymphocytes and vascular inflammation contribute to stress-dependent hypertension
    • Marvar P.J., Vinh A., Thabet S., Lob H.E., Geem D., Ressler K.J., et al. T lymphocytes and vascular inflammation contribute to stress-dependent hypertension. Biol Psychiatry 2012, 71(9):774-782.
    • (2012) Biol Psychiatry , vol.71 , Issue.9 , pp. 774-782
    • Marvar, P.J.1    Vinh, A.2    Thabet, S.3    Lob, H.E.4    Geem, D.5    Ressler, K.J.6
  • 12
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112(12):1821.
    • (2003) J Clin Invest , vol.112 , Issue.12 , pp. 1821
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3    Tan, G.4    Yang, D.5    Chou, C.J.6
  • 14
    • 77956013253 scopus 로고    scopus 로고
    • Mini review: Inflammation and obesity pathogenesis: the hypothalamus heats up
    • Thaler J.P., Schwartz M.W. Mini review: Inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology 2010, 151(9):4109-4115.
    • (2010) Endocrinology , vol.151 , Issue.9 , pp. 4109-4115
    • Thaler, J.P.1    Schwartz, M.W.2
  • 15
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani P.D., Amar J., Iglesias M.A., Poggi M., Knauf C., Bastelica D., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007, 56(7):1761-1772.
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3    Poggi, M.4    Knauf, C.5    Bastelica, D.6
  • 16
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • Shoelson S.E., Lee J., Goldfine A.B.. Inflammation and insulin resistance. J Clin Invest 2006, 116(7):1793-1801.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 17
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
    • Zhang X., Zhang G., Zhang H., Karin M., Bai H., Cai D. Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 2008, 135(1):61-73.
    • (2008) Cell , vol.135 , Issue.1 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 18
    • 83655184676 scopus 로고    scopus 로고
    • Angiotensin II-induced hypertension is modulated by nuclear factor-kappaBin the paraventricular nucleus
    • Cardinale J.P., Sriramula S., Mariappan N., Agarwal D., Francis J. Angiotensin II-induced hypertension is modulated by nuclear factor-kappaBin the paraventricular nucleus. Hypertension 2012, 59(1):113-121.
    • (2012) Hypertension , vol.59 , Issue.1 , pp. 113-121
    • Cardinale, J.P.1    Sriramula, S.2    Mariappan, N.3    Agarwal, D.4    Francis, J.5
  • 19
    • 66249130392 scopus 로고    scopus 로고
    • Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension
    • Kang Y.M., Ma Y., Zheng J.P., Elks C., Sriramula S., Yang Z.M., et al. Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension. Cardiovasc Res 2009, 82(3):503-512.
    • (2009) Cardiovasc Res , vol.82 , Issue.3 , pp. 503-512
    • Kang, Y.M.1    Ma, Y.2    Zheng, J.P.3    Elks, C.4    Sriramula, S.5    Yang, Z.M.6
  • 20
    • 53049094903 scopus 로고    scopus 로고
    • Specific inflammatory condition in nucleus tractus solitarii of the SHR: novel insight for neurogenic hypertension?
    • Waki H., Gouraud S.S., Maeda M., Paton J.F. Specific inflammatory condition in nucleus tractus solitarii of the SHR: novel insight for neurogenic hypertension?. Auton Neurosci 2008, 142(1-2):25-31.
    • (2008) Auton Neurosci , vol.142 , Issue.1-2 , pp. 25-31
    • Waki, H.1    Gouraud, S.S.2    Maeda, M.3    Paton, J.F.4
  • 21
    • 53049101580 scopus 로고    scopus 로고
    • Gene expression profiles of major cytokines in the nucleus tractus solitarii of the spontaneously hypertensive rat
    • Waki H., Gouraud S.S., Maeda M., Paton J.F. Gene expression profiles of major cytokines in the nucleus tractus solitarii of the spontaneously hypertensive rat. Auton Neurosci 2008, 142(1-2):40-44.
    • (2008) Auton Neurosci , vol.142 , Issue.1-2 , pp. 40-44
    • Waki, H.1    Gouraud, S.S.2    Maeda, M.3    Paton, J.F.4
  • 22
    • 34249323041 scopus 로고    scopus 로고
    • Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem
    • Waki H., Liu B., Miyake M., Katahira K., Murphy D., Kasparov S., et al. Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem. Hypertension 2007, 49(6):1321-1327.
    • (2007) Hypertension , vol.49 , Issue.6 , pp. 1321-1327
    • Waki, H.1    Liu, B.2    Miyake, M.3    Katahira, K.4    Murphy, D.5    Kasparov, S.6
  • 23
    • 58849149821 scopus 로고    scopus 로고
    • Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity
    • Milanski M., Degasperi G., Coope A., Morari J., Denis R., Cintra D.E., et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. J Neurosci 2009, 29(2):359-370.
    • (2009) J Neurosci , vol.29 , Issue.2 , pp. 359-370
    • Milanski, M.1    Degasperi, G.2    Coope, A.3    Morari, J.4    Denis, R.5    Cintra, D.E.6
  • 24
    • 8544237784 scopus 로고    scopus 로고
    • Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis
    • Wisse B.E., Ogimoto K., Morton G.J., Wilkinson C.W., Frayo R.S., Cummings D.E., et al. Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis. Am J Physiol Endocrinol Metab 2004, 287(6):E1107-E1113.
    • (2004) Am J Physiol Endocrinol Metab , vol.287 , Issue.6 , pp. E1107-E1113
    • Wisse, B.E.1    Ogimoto, K.2    Morton, G.J.3    Wilkinson, C.W.4    Frayo, R.S.5    Cummings, D.E.6
  • 25
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani P.D., Bibiloni R., Knauf C., Waget A., Neyrinck A.M., Delzenne N.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008, 57(6):1470-1481.
    • (2008) Diabetes , vol.57 , Issue.6 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 27
    • 79960117277 scopus 로고    scopus 로고
    • Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-beta and NF-kappaB
    • Purkayastha S., Zhang G., Cai D. Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-beta and NF-kappaB. Nat Med 2011, 17(7):883-887.
    • (2011) Nat Med , vol.17 , Issue.7 , pp. 883-887
    • Purkayastha, S.1    Zhang, G.2    Cai, D.3
  • 28
    • 55849141253 scopus 로고    scopus 로고
    • Central control of body weight and appetite
    • Woods S.C., D'Alessio D.A. Central control of body weight and appetite. J Clin Endocrinol Metab 2008, 93(11 Suppl. 1):S37-S50.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.11 , pp. S37-S50
    • Woods, S.C.1    D'Alessio, D.A.2
  • 29
    • 84874927549 scopus 로고    scopus 로고
    • Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity
    • de Kloet A.D., Pati D., Wang L., Hiller H., Sumners C., Frazier C.J., et al. Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity. J Neurosci 2013, 33(11):4825-4833.
    • (2013) J Neurosci , vol.33 , Issue.11 , pp. 4825-4833
    • de Kloet, A.D.1    Pati, D.2    Wang, L.3    Hiller, H.4    Sumners, C.5    Frazier, C.J.6
  • 31
    • 27544450765 scopus 로고    scopus 로고
    • Divergence of melanocortin pathways in the control of food intake and energy expenditure
    • Balthasar N., Dalgaard L.T., Lee C.E., Yu J., Funahashi H., Williams T., et al. Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell 2005, 123(3):493-505.
    • (2005) Cell , vol.123 , Issue.3 , pp. 493-505
    • Balthasar, N.1    Dalgaard, L.T.2    Lee, C.E.3    Yu, J.4    Funahashi, H.5    Williams, T.6
  • 33
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: the missing link in neuroprotection and neurodegeneration?
    • Nguyen M.D., Julien J.P., Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration?. Nat Rev Neurosci 2002, 3(3):216-227.
    • (2002) Nat Rev Neurosci , vol.3 , Issue.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 34
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996, 19(8):312-318.
    • (1996) Trends Neurosci , vol.19 , Issue.8 , pp. 312-318
    • Kreutzberg, G.W.1
  • 35
    • 0034866550 scopus 로고    scopus 로고
    • Microglia: activation and their significance in the central nervous system
    • Nakajima K., Kohsaka S. Microglia: activation and their significance in the central nervous system. J Biochem 2001, 130(2):169-175.
    • (2001) J Biochem , vol.130 , Issue.2 , pp. 169-175
    • Nakajima, K.1    Kohsaka, S.2
  • 36
    • 79960941611 scopus 로고    scopus 로고
    • The corticotropin-releasing hormone network and the hypothalamic-pituitary-adrenal axis: molecular and cellular mechanisms involved
    • Bonfiglio J.J., Inda C., Refojo D., Holsboer F., Arzt E., Silberstein S. The corticotropin-releasing hormone network and the hypothalamic-pituitary-adrenal axis: molecular and cellular mechanisms involved. Neuroendocrinology 2011, 94(1):12-20.
    • (2011) Neuroendocrinology , vol.94 , Issue.1 , pp. 12-20
    • Bonfiglio, J.J.1    Inda, C.2    Refojo, D.3    Holsboer, F.4    Arzt, E.5    Silberstein, S.6
  • 37
    • 84866760652 scopus 로고    scopus 로고
    • Antiinflammatory treatment ameliorates HPA stress axis dysfunction in a mouse model of stress sensitivity
    • Gerber A.R., Bale T.L. Antiinflammatory treatment ameliorates HPA stress axis dysfunction in a mouse model of stress sensitivity. Endocrinology 2012, 153(10):4830-4837.
    • (2012) Endocrinology , vol.153 , Issue.10 , pp. 4830-4837
    • Gerber, A.R.1    Bale, T.L.2
  • 38
    • 84874156024 scopus 로고    scopus 로고
    • Regional astrogliosis in the mouse hypothalamus in response to obesity
    • Buckman L.B., Thompson M.M., Moreno H.N., Ellacott K.L.J. Regional astrogliosis in the mouse hypothalamus in response to obesity. J Comp Neurol 2013, 521(6):1322-1333.
    • (2013) J Comp Neurol , vol.521 , Issue.6 , pp. 1322-1333
    • Buckman, L.B.1    Thompson, M.M.2    Moreno, H.N.3    Ellacott, K.L.J.4
  • 39
    • 77249153620 scopus 로고    scopus 로고
    • Cognitive impairment following high fat diet consumption is associated with brain inflammation
    • Pistell P.J., Morrison C.D., Gupta S., Knight A.G., Keller J.N., Ingram D.K., et al. Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol 2010, 219(1-2):25-32.
    • (2010) J Neuroimmunol , vol.219 , Issue.1-2 , pp. 25-32
    • Pistell, P.J.1    Morrison, C.D.2    Gupta, S.3    Knight, A.G.4    Keller, J.N.5    Ingram, D.K.6
  • 40
    • 77957053600 scopus 로고    scopus 로고
    • Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity
    • Horvath T.L., Sarman B., Garcia-Caceres C., Enriori P.J., Sotonyi P., Shanabrough M., et al. Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity. Proc Natl Acad Sci U S A 2010, 107(33):14875-14880.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.33 , pp. 14875-14880
    • Horvath, T.L.1    Sarman, B.2    Garcia-Caceres, C.3    Enriori, P.J.4    Sotonyi, P.5    Shanabrough, M.6
  • 41
    • 24944438230 scopus 로고    scopus 로고
    • Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
    • De Souza C.T., Araujo E.P., Bordin S., Ashimine R., Zollner R.L., Boschero A.C., et al. Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology 2005, 146(10):4192-4199.
    • (2005) Endocrinology , vol.146 , Issue.10 , pp. 4192-4199
    • De Souza, C.T.1    Araujo, E.P.2    Bordin, S.3    Ashimine, R.4    Zollner, R.L.5    Boschero, A.C.6
  • 42
    • 2542443633 scopus 로고    scopus 로고
    • Increased expression of glial fibrillary acidic protein in the brain of spontaneously hypertensive rats
    • Tomassoni D., Avola R., Di Tullio M.A., Sabbatini M., Vitaioli L., Amenta F. Increased expression of glial fibrillary acidic protein in the brain of spontaneously hypertensive rats. Clin Exp Hypertens 2004, 26(4):335-350.
    • (2004) Clin Exp Hypertens , vol.26 , Issue.4 , pp. 335-350
    • Tomassoni, D.1    Avola, R.2    Di Tullio, M.A.3    Sabbatini, M.4    Vitaioli, L.5    Amenta, F.6
  • 44
    • 0030864345 scopus 로고    scopus 로고
    • Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review
    • Lenkei Z., Palkovits M., Corvol P., Llorens-Cortès C. Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review. Front Neuroendocrinol 1997, 18(4):383.
    • (1997) Front Neuroendocrinol , vol.18 , Issue.4 , pp. 383
    • Lenkei, Z.1    Palkovits, M.2    Corvol, P.3    Llorens-Cortès, C.4
  • 45
    • 0345195987 scopus 로고    scopus 로고
    • Characterization and distribution of angiotensin II receptor subtypes in the mouse brain
    • Hauser W., Johren O., Saavedra J.M. Characterization and distribution of angiotensin II receptor subtypes in the mouse brain. Eur J Pharmacol 1998, 348(1):101-114.
    • (1998) Eur J Pharmacol , vol.348 , Issue.1 , pp. 101-114
    • Hauser, W.1    Johren, O.2    Saavedra, J.M.3
  • 46
    • 84873056531 scopus 로고    scopus 로고
    • Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension
    • Lob H.E., Schultz D., Marvar P.J., Davisson R.L., Harrison D.G. Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension 2013, 61(2):382-387.
    • (2013) Hypertension , vol.61 , Issue.2 , pp. 382-387
    • Lob, H.E.1    Schultz, D.2    Marvar, P.J.3    Davisson, R.L.4    Harrison, D.G.5
  • 47
    • 84874360680 scopus 로고    scopus 로고
    • Angiotensin type 1a receptors in the subfornical organ are required for deoxycorticosterone acetate-salt hypertension
    • Hilzendeger A.M., Cassell M.D., Davis D.R., Stauss H.M., Mark A.L., Grobe J.L., et al. Angiotensin type 1a receptors in the subfornical organ are required for deoxycorticosterone acetate-salt hypertension. Hypertension 2013, 61(3):716-722.
    • (2013) Hypertension , vol.61 , Issue.3 , pp. 716-722
    • Hilzendeger, A.M.1    Cassell, M.D.2    Davis, D.R.3    Stauss, H.M.4    Mark, A.L.5    Grobe, J.L.6
  • 48
    • 84868626624 scopus 로고    scopus 로고
    • ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension
    • Young C.N., Cao X., Guruju M.R., Pierce J.P., Morgan D.A., Wang G., et al. ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension. J Clin Invest 2012, 122(11):3960-3964.
    • (2012) J Clin Invest , vol.122 , Issue.11 , pp. 3960-3964
    • Young, C.N.1    Cao, X.2    Guruju, M.R.3    Pierce, J.P.4    Morgan, D.A.5    Wang, G.6
  • 49
    • 51349117272 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor in hypothalamic paraventricular nucleus neurons decreases blood pressure in spontaneously hypertensive rats
    • Li H., Gao Y., Qi Y., Katovich M.J., Jiang N., Braseth L.N., et al. Macrophage migration inhibitory factor in hypothalamic paraventricular nucleus neurons decreases blood pressure in spontaneously hypertensive rats. FASEB J 2008, 22(9):3175-3185.
    • (2008) FASEB J , vol.22 , Issue.9 , pp. 3175-3185
    • Li, H.1    Gao, Y.2    Qi, Y.3    Katovich, M.J.4    Jiang, N.5    Braseth, L.N.6
  • 50
    • 33644553529 scopus 로고    scopus 로고
    • The subfornical organ: a central target for circulating feeding signals
    • Pulman K.J., Fry W.M., Cottrell G.T., Ferguson A.V. The subfornical organ: a central target for circulating feeding signals. J Neurosci 2006, 26(7):2022-2030.
    • (2006) J Neurosci , vol.26 , Issue.7 , pp. 2022-2030
    • Pulman, K.J.1    Fry, W.M.2    Cottrell, G.T.3    Ferguson, A.V.4
  • 51
    • 84877035638 scopus 로고    scopus 로고
    • Bidirectional neuro-glial signaling modalities in the hypothalamus: role in neurohumoral regulation
    • Stern J.E., Filosa J.A. Bidirectional neuro-glial signaling modalities in the hypothalamus: role in neurohumoral regulation. Auton Neurosci 2013, 175(1-2):51-60.
    • (2013) Auton Neurosci , vol.175 , Issue.1-2 , pp. 51-60
    • Stern, J.E.1    Filosa, J.A.2
  • 52
    • 70350397908 scopus 로고    scopus 로고
    • Regulation of tonic GABA inhibitory function, presympathetic neuronal activity and sympathetic outflow from the paraventricular nucleus by astroglial GABA transporters
    • Park J.B., Jo J.Y., Zheng H., Patel K.P., Stern J.E. Regulation of tonic GABA inhibitory function, presympathetic neuronal activity and sympathetic outflow from the paraventricular nucleus by astroglial GABA transporters. J Physiol 2009, 587(Pt 19):4645-4660.
    • (2009) J Physiol , vol.587 , pp. 4645-4660
    • Park, J.B.1    Jo, J.Y.2    Zheng, H.3    Patel, K.P.4    Stern, J.E.5
  • 55
    • 83655184758 scopus 로고    scopus 로고
    • Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage
    • Zhang W., Wang W., Yu H., Zhang Y., Dai Y., Ning C., et al. Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage. Hypertension 2012, 59(1):136-144.
    • (2012) Hypertension , vol.59 , Issue.1 , pp. 136-144
    • Zhang, W.1    Wang, W.2    Yu, H.3    Zhang, Y.4    Dai, Y.5    Ning, C.6
  • 56
    • 80052964672 scopus 로고    scopus 로고
    • Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans
    • Chamarthi B., Williams G.H., Ricchiuti V., Srikumar N., Hopkins P.N., Luther J.M., et al. Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans. Am J Hypertens 2011, 24(10):1143-1148.
    • (2011) Am J Hypertens , vol.24 , Issue.10 , pp. 1143-1148
    • Chamarthi, B.1    Williams, G.H.2    Ricchiuti, V.3    Srikumar, N.4    Hopkins, P.N.5    Luther, J.M.6
  • 57
    • 67149125523 scopus 로고    scopus 로고
    • Interleukin-6 gene knockout influences energy balance regulating peptides in the hypothalamic paraventricular and supraoptic nuclei
    • Benrick A., Schéle E., Pinnock S.B., Wernstedt-Asterholm I., Dickson S.L., Karlsson-Lindahl L., et al. Interleukin-6 gene knockout influences energy balance regulating peptides in the hypothalamic paraventricular and supraoptic nuclei. J Neuroendocrinol 2009, 21(7):620-628.
    • (2009) J Neuroendocrinol , vol.21 , Issue.7 , pp. 620-628
    • Benrick, A.1    Schéle, E.2    Pinnock, S.B.3    Wernstedt-Asterholm, I.4    Dickson, S.L.5    Karlsson-Lindahl, L.6
  • 58
    • 37249074063 scopus 로고    scopus 로고
    • The role of interleukin-6 in insulin resistance, body fat distribution and energy balance
    • Hoene M., Weigert C. The role of interleukin-6 in insulin resistance, body fat distribution and energy balance. Obes Rev 2008, 9(1):20-29.
    • (2008) Obes Rev , vol.9 , Issue.1 , pp. 20-29
    • Hoene, M.1    Weigert, C.2
  • 60
    • 80054734904 scopus 로고    scopus 로고
    • Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress
    • Krause E.G., de Kloet A.D., Scott K.A., Flak J.N., Jones K., Smeltzer M.D., et al. Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress. J Neurosci 2011, 31(42):15009-15015.
    • (2011) J Neurosci , vol.31 , Issue.42 , pp. 15009-15015
    • Krause, E.G.1    de Kloet, A.D.2    Scott, K.A.3    Flak, J.N.4    Jones, K.5    Smeltzer, M.D.6
  • 61
    • 66149118129 scopus 로고    scopus 로고
    • Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
    • Posey K.A., Clegg D.J., Printz R.L., Byun J., Morton G.J., Vivekanandan-Giri A., et al. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 2009, 296(5):E1003-E1012.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , Issue.5 , pp. E1003-E1012
    • Posey, K.A.1    Clegg, D.J.2    Printz, R.L.3    Byun, J.4    Morton, G.J.5    Vivekanandan-Giri, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.