-
1
-
-
0032524656
-
Adenovirus E1B-19 K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence
-
PID: 9575197, COI: 1:CAS:528:DyaK1cXjtlSgtb0%3D
-
Yasuda M, Theodorakis P, Subramanian T, Chinnadurai G (1998) Adenovirus E1B-19 K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J Biol Chem 273:12415–12421
-
(1998)
J Biol Chem
, vol.273
, pp. 12415-12421
-
-
Yasuda, M.1
Theodorakis, P.2
Subramanian, T.3
Chinnadurai, G.4
-
2
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
PID: 7954800, COI: 1:CAS:528:DyaK2MXhvFWrtr4%3D
-
Boyd JM, Malstrom S, Subramanian T, Venkatesh LK, Schaeper U, Elangovan B et al (1994) Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79:341–351
-
(1994)
Cell
, vol.79
, pp. 341-351
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
Venkatesh, L.K.4
Schaeper, U.5
Elangovan, B.6
-
3
-
-
0031455410
-
The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis
-
PID: 9396766, COI: 1:CAS:528:DyaK2sXotVGhs7k%3D
-
Chen G, Ray R, Dubik D, Shi L, Cizeau J, Bleackley RC et al (1997) The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis. J Exp Med 186:1975–1983
-
(1997)
J Exp Med
, vol.186
, pp. 1975-1983
-
-
Chen, G.1
Ray, R.2
Dubik, D.3
Shi, L.4
Cizeau, J.5
Bleackley, R.C.6
-
4
-
-
0022971952
-
Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
-
PID: 2876518, COI: 1:CAS:528:DyaL28XmtVGjsb4%3D
-
Rogers S, Wells R, Rechsteiner M (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234:364–368
-
(1986)
Science
, vol.234
, pp. 364-368
-
-
Rogers, S.1
Wells, R.2
Rechsteiner, M.3
-
5
-
-
57049172037
-
Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion
-
PID: 18790835, COI: 1:CAS:528:DC%2BD1cXhsVWktb3M
-
Kubli DA, Quinsay MN, Lee Y, Gustafsson AB (2008) Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol 295:H2025–H2031
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, pp. H2025-H2031
-
-
Kubli, D.A.1
Quinsay, M.N.2
Lee, Y.3
Gustafsson, A.B.4
-
6
-
-
0033942613
-
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
-
Vande VC, Cizeau J, Dubik D, Alimonti J, Brown T, Israels S, Hakem R, Greenberg AH (2000) BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 20:5454–5468
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5454-5468
-
-
Vande, V.C.1
Cizeau, J.2
Dubik, D.3
Alimonti, J.4
Brown, T.5
Israels, S.6
Hakem, R.7
Greenberg, A.H.8
-
7
-
-
0033068143
-
BNIP3alpha: A human homolog of mitochondrial proapoptotic protein BNIP3
-
PID: 9973195, COI: 1:CAS:528:DyaK1MXhtV2rsrc%3D
-
Yasuda M, Han JW, Dionne CA, Boyd JM, Chinnadurai G (1999) BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. Cancer Res 59(3):533–537
-
(1999)
Cancer Res
, vol.59
, Issue.3
, pp. 533-537
-
-
Yasuda, M.1
Han, J.W.2
Dionne, C.A.3
Boyd, J.M.4
Chinnadurai, G.5
-
8
-
-
0032932923
-
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
-
PID: 9867803, COI: 1:CAS:528:DyaK1MXjvVWgtA%3D%3D
-
Chen G, Cizeau J, Vande Velde C, Park JH, Bozek G, Bolton J, Shi L, Dubik D, Greenberg A (1999) Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J Biol Chem 274(1):7–10
-
(1999)
J Biol Chem
, vol.274
, Issue.1
, pp. 7-10
-
-
Chen, G.1
Cizeau, J.2
Vande Velde, C.3
Park, J.H.4
Bozek, G.5
Bolton, J.6
Shi, L.7
Dubik, D.8
Greenberg, A.9
-
9
-
-
27944470616
-
Phylogenomics of life-or-death switches in multicellular animals: Bcl-2, BH3-Only, and BNip families of apoptotic regulators
-
PID: 16093567, COI: 1:CAS:528:DC%2BD2MXht1KgtLnI
-
Aouacheria A, Brunet F, Gouy M (2005) Phylogenomics of life-or-death switches in multicellular animals: Bcl-2, BH3-Only, and BNip families of apoptotic regulators. Mol Biol Evol 22(12):2395–2416
-
(2005)
Mol Biol Evol
, vol.22
, Issue.12
, pp. 2395-2416
-
-
Aouacheria, A.1
Brunet, F.2
Gouy, M.3
-
10
-
-
0034681110
-
Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity
-
PID: 10639121, COI: 1:CAS:528:DC%2BD3cXot1ajtA%3D%3D
-
Shimizu S, Tsujimoto Y (2000) Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity. Proc Natl Acad Sci USA 97(2):577–582
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.2
, pp. 577-582
-
-
Shimizu, S.1
Tsujimoto, Y.2
-
11
-
-
0034711953
-
The GxxxG motif: A framework for transmembrane helix–helix association
-
PID: 10677291, COI: 1:CAS:528:DC%2BD3cXhtFakt74%3D
-
Russ WP, Engelman DM (2000) The GxxxG motif: a framework for transmembrane helix–helix association. J Mol Biol 296:911–919
-
(2000)
J Mol Biol
, vol.296
, pp. 911-919
-
-
Russ, W.P.1
Engelman, D.M.2
-
12
-
-
0345802999
-
Sequence-specific dimerization of the transmembrane domain of the “BH3-only” protein BNIP3 in membranes and detergent
-
PID: 14532263, COI: 1:CAS:528:DC%2BD3sXpslOgu7w%3D
-
Sulistijo ES, Jaszewski TM, MacKenzie KR (2003) Sequence-specific dimerization of the transmembrane domain of the “BH3-only” protein BNIP3 in membranes and detergent. J Biol Chem 278:51950–51956
-
(2003)
J Biol Chem
, vol.278
, pp. 51950-51956
-
-
Sulistijo, E.S.1
Jaszewski, T.M.2
MacKenzie, K.R.3
-
13
-
-
33947401373
-
Mutagenesis data in the automated prediction of transmembrane helix dimers
-
Metcal DG, Law PB, DeGrado WF (2007) Mutagenesis data in the automated prediction of transmembrane helix dimers. Proteins 67:375–384
-
(2007)
Proteins
, vol.67
, pp. 375-384
-
-
Metcal, D.G.1
Law, P.B.2
DeGrado, W.F.3
-
14
-
-
33751088317
-
Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix–helix interactions
-
PID: 17049556, COI: 1:CAS:528:DC%2BD28Xht1eqtbfF
-
Sulistijo ES, MacKenzie KR (2006) Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix–helix interactions. J Mol Biol 364:974–990
-
(2006)
J Mol Biol
, vol.364
, pp. 974-990
-
-
Sulistijo, E.S.1
MacKenzie, K.R.2
-
15
-
-
26444611461
-
Transmembrane glycine zippers: Physiological and pathological roles in membrane proteins
-
PID: 16179394, COI: 1:CAS:528:DC%2BD2MXhtFChu7fL
-
Kim S, Jeon TJ, Oberai A, Yang D, Schmidt JJ, Bowie JU (2005) Transmembrane glycine zippers: physiological and pathological roles in membrane proteins. Proc Natl Acad Sci USA 102:14278–14283
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14278-14283
-
-
Kim, S.1
Jeon, T.J.2
Oberai, A.3
Yang, D.4
Schmidt, J.J.5
Bowie, J.U.6
-
16
-
-
34447523353
-
Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger
-
PID: 17412696, COI: 1:CAS:528:DC%2BD2sXlvVajtrk%3D
-
Bocharov EV, Pustovalova YE, Pavlov KV, Volynsky PE, Goncharuk MV, Ermolyuk YS, Karpunin DV, Schulga AA, Kirpichnikov MP, Efremov RG, Maslennikov IV, Arseniev AS (2007) Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger. J Biol Chem 282(22):16256–16266
-
(2007)
J Biol Chem
, vol.282
, Issue.22
, pp. 16256-16266
-
-
Bocharov, E.V.1
Pustovalova, Y.E.2
Pavlov, K.V.3
Volynsky, P.E.4
Goncharuk, M.V.5
Ermolyuk, Y.S.6
Karpunin, D.V.7
Schulga, A.A.8
Kirpichnikov, M.P.9
Efremov, R.G.10
Maslennikov, I.V.11
Arseniev, A.S.12
-
17
-
-
0035030534
-
Hypoxia induces the expression of the pro-apoptotic gene BNIP3
-
PID: 11550088, COI: 1:CAS:528:DC%2BD3MXktVOmsbY%3D
-
Guo K, Searfoss G, Krolikowski D, Pagnoni M, Franks C, Clark K et al (2001) Hypoxia induces the expression of the pro-apoptotic gene BNIP3. Cell Death Differ 8:367–376
-
(2001)
Cell Death Differ
, vol.8
, pp. 367-376
-
-
Guo, K.1
Searfoss, G.2
Krolikowski, D.3
Pagnoni, M.4
Franks, C.5
Clark, K.6
-
18
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
PID: 10922063, COI: 1:CAS:528:DC%2BD3cXls12ksrg%3D
-
Bruick RK (2000) Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97:9082–9087
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
19
-
-
0035884701
-
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
PID: 11559532, COI: 1:CAS:528:DC%2BD3MXntFaisrc%3D
-
Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL (2001) HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 61:6669–6673
-
(2001)
Cancer Res
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
Ratcliffe, P.J.2
Watson, P.3
Greenberg, A.H.4
Harris, A.L.5
-
20
-
-
77952672872
-
Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism
-
PID: 20025887, COI: 1:CAS:528:DC%2BC3cXlvVels7g%3D
-
Quinsay Melissa N, Lee Y, Shivaji Rikka M, Sayen R, Molkentin Jeffery D, Gottlieb Roberta A, Gustafsson ÅB (2010) Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism. J Mol Cell Cardiol 48(6):1146–1156
-
(2010)
J Mol Cell Cardiol
, vol.48
, Issue.6
, pp. 1146-1156
-
-
Quinsay, M.N.1
Lee, Y.2
Shivaji Rikka, M.3
Sayen, R.4
Molkentin, J.D.5
Gottlieb, R.A.6
Gustafsson, Å.B.7
-
21
-
-
0035876483
-
BH3-only proteins that bind prosurvival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
PID: 11410528, COI: 1:CAS:528:DC%2BD3MXksFKgtbg%3D
-
Zong WX, Lindsten T, Ross AJ, MacGregor GR, Thompson CB (2001) BH3-only proteins that bind prosurvival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 15(12):1481–1486
-
(2001)
Genes Dev
, vol.15
, Issue.12
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
22
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
PID: 11326099, COI: 1:CAS:528:DC%2BD3MXjt1eltr0%3D
-
Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292(5517):727–730
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
-
23
-
-
0036789917
-
Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3
-
PID: 12226479, COI: 1:CAS:528:DC%2BD38XnvFGhsbo%3D
-
Kubasiak LA, Hernandez OM, Bishopric NH, Webster KA (2002) Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc Natl Acad Sci USA 99:12825–12830
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12825-12830
-
-
Kubasiak, L.A.1
Hernandez, O.M.2
Bishopric, N.H.3
Webster, K.A.4
-
24
-
-
0037047647
-
Inducible expression of BNIP3 provokes mitochondrial defects and hypoxiamediated cell death of ventricular myocytes
-
PID: 12169648, COI: 1:CAS:528:DC%2BD38Xmt12jtb8%3D
-
Regula KM, Ens K, Kirshenbaum LA (2002) Inducible expression of BNIP3 provokes mitochondrial defects and hypoxiamediated cell death of ventricular myocytes. Circ Res 91:226–231
-
(2002)
Circ Res
, vol.91
, pp. 226-231
-
-
Regula, K.M.1
Ens, K.2
Kirshenbaum, L.A.3
-
25
-
-
34547471625
-
Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak
-
PID: 17447897, COI: 1:CAS:528:DC%2BD2sXns12gsrw%3D
-
Kubli DA, Ycaza JE, Gustafsson AB (2007) Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak. Biochem J 405:407–415
-
(2007)
Biochem J
, vol.405
, pp. 407-415
-
-
Kubli, D.A.1
Ycaza, J.E.2
Gustafsson, A.B.3
-
26
-
-
77952672872
-
Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism
-
PID: 20025887, COI: 1:CAS:528:DC%2BC3cXlvVels7g%3D
-
Quinsay MN, Lee Y, Rikka S, Sayen MR, Molkentin JD, Gottlieb RA, Gustafsson AB (2010) Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanism. J Mol Cell Cardiol 48:1146–1156
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 1146-1156
-
-
Quinsay, M.N.1
Lee, Y.2
Rikka, S.3
Sayen, M.R.4
Molkentin, J.D.5
Gottlieb, R.A.6
Gustafsson, A.B.7
-
27
-
-
77953123212
-
The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms
-
PID: 20436456, COI: 1:CAS:528:DC%2BC3cXltl2lsbg%3D
-
Landes T, Emorine LJ, Courilleau D, Rojo M, Belenguer P, Arnaune-Pelloquin L (2010) The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms. EMBO Rep 11:459–465
-
(2010)
EMBO Rep
, vol.11
, pp. 459-465
-
-
Landes, T.1
Emorine, L.J.2
Courilleau, D.3
Rojo, M.4
Belenguer, P.5
Arnaune-Pelloquin, L.6
-
28
-
-
0038267444
-
CD47 and the 19 kDa interacting protein-3 (BNIP3) in T cell apoptosis
-
PID: 12690108, COI: 1:CAS:528:DC%2BD3sXkslygurY%3D
-
Lamy L, Ticchioni M, Rouquette-Jazdanian AK, Samson M, Deckert M, Greenberg AH et al (2003) CD47 and the 19 kDa interacting protein-3 (BNIP3) in T cell apoptosis. J Biol Chem 278:23915–23921
-
(2003)
J Biol Chem
, vol.278
, pp. 23915-23921
-
-
Lamy, L.1
Ticchioni, M.2
Rouquette-Jazdanian, A.K.3
Samson, M.4
Deckert, M.5
Greenberg, A.H.6
-
29
-
-
33745272512
-
Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells
-
PID: 16740734, COI: 1:CAS:528:DC%2BD28XltFyjurY%3D
-
Bandyopadhyay S, Zhan R, Wang Y, Pai SK, Hirota S, Hosobe S et al (2006) Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells. Cancer Res 66:5934–5940
-
(2006)
Cancer Res
, vol.66
, pp. 5934-5940
-
-
Bandyopadhyay, S.1
Zhan, R.2
Wang, Y.3
Pai, S.K.4
Hirota, S.5
Hosobe, S.6
-
30
-
-
0029910628
-
Loss of Rb activates both p53-dependent and -independent cell death pathways in the developing mouse nervous system
-
PID: 8947040, COI: 1:CAS:528:DyaK28XnsFKrt7c%3D
-
Macleod K, Hu Y, Jacks T (1996) Loss of Rb activates both p53-dependent and -independent cell death pathways in the developing mouse nervous system. EMBO J 15:6178–6188
-
(1996)
EMBO J
, vol.15
, pp. 6178-6188
-
-
Macleod, K.1
Hu, Y.2
Jacks, T.3
-
31
-
-
34548235820
-
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy
-
PID: 17576813, COI: 1:CAS:528:DC%2BD2sXpvFGgt7Y%3D
-
Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF (2007) BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol 27:6229–6242
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6229-6242
-
-
Tracy, K.1
Dibling, B.C.2
Spike, B.T.3
Knabb, J.R.4
Schumacker, P.5
Macleod, K.F.6
-
32
-
-
41949101511
-
The cell cycle factor E2F-1 activates Bnip3 and the intrinsic death pathway in ventricular myocytes
-
PID: 18096822, COI: 1:CAS:528:DC%2BD1cXitl2jsrk%3D
-
Yurkova N, Shaw J, Blackie K, Weidman D, Jayas R, Flynn B et al (2008) The cell cycle factor E2F-1 activates Bnip3 and the intrinsic death pathway in ventricular myocytes. Circ Res 102:472–479
-
(2008)
Circ Res
, vol.102
, pp. 472-479
-
-
Yurkova, N.1
Shaw, J.2
Blackie, K.3
Weidman, D.4
Jayas, R.5
Flynn, B.6
-
33
-
-
0037013206
-
A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis
-
PID: 11832486, COI: 1:CAS:528:DC%2BD38Xjs1Wjsbc%3D
-
Mizutani A, Furukawa T, Adachi Y, Ikehara S, Taketani S (2002) A zinc-finger protein, PLAGL2, induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis. J Biol Chem 277:15851–15858
-
(2002)
J Biol Chem
, vol.277
, pp. 15851-15858
-
-
Mizutani, A.1
Furukawa, T.2
Adachi, Y.3
Ikehara, S.4
Taketani, S.5
-
34
-
-
43949109275
-
Downstream of Akt: Foxo3 and mTOR in the regulation of autophagy in skeletal muscle
-
PID: 18367868, COI: 1:CAS:528:DC%2BD1cXntFymsrw%3D
-
Mammucari C, Schiaffino S, Sandri M (2008) Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle. Autophagy 4:524–526
-
(2008)
Autophagy
, vol.4
, pp. 524-526
-
-
Mammucari, C.1
Schiaffino, S.2
Sandri, M.3
-
35
-
-
33845612203
-
Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes
-
PID: 17082476, COI: 1:CAS:528:DC%2BD28Xht1Ohu77L
-
Shaw J, Zhang T, Rzeszutek M, Yurkova N, Baetz D, Davie JR, Kirshenbaum LA (2006) Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes. Circ Res 99:1347–1354
-
(2006)
Circ Res
, vol.99
, pp. 1347-1354
-
-
Shaw, J.1
Zhang, T.2
Rzeszutek, M.3
Yurkova, N.4
Baetz, D.5
Davie, J.R.6
Kirshenbaum, L.A.7
-
36
-
-
58549107366
-
Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival
-
PID: 19088195, COI: 1:CAS:528:DC%2BD1MXks1Glug%3D%3D
-
Shaw J, Yurkova N, Zhang T, Gang H, Aguilar F, Weidman D et al (2008) Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival. Proc Natl Acad Sci USA 105:20734–20739
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20734-20739
-
-
Shaw, J.1
Yurkova, N.2
Zhang, T.3
Gang, H.4
Aguilar, F.5
Weidman, D.6
-
37
-
-
34548856780
-
Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death
-
PID: 17623653, COI: 1:CAS:528:DC%2BD2sXpslGjtrs%3D
-
Ha SD, Ng D, Lamothe J, Valvano MA, Han J, Kim SO (2007) Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death. J Biol Chem 282:26275–26283
-
(2007)
J Biol Chem
, vol.282
, pp. 26275-26283
-
-
Ha, S.D.1
Ng, D.2
Lamothe, J.3
Valvano, M.A.4
Han, J.5
Kim, S.O.6
-
38
-
-
34547875432
-
Regulation of bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation
-
PID: 17638546, COI: 1:CAS:528:DC%2BD2sXosVykurs%3D
-
Graham RM, Thompson JW, Wei J, Bishopric NH, Webster KA (2007) Regulation of bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation. Antioxid Redox Signal 9:1309–1316
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1309-1316
-
-
Graham, R.M.1
Thompson, J.W.2
Wei, J.3
Bishopric, N.H.4
Webster, K.A.5
-
39
-
-
33845511362
-
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
-
PID: 16645637, COI: 1:CAS:528:DC%2BD28XhtlSqur7I
-
Hamacher-Brady A, Brady NR, Logue SE, Sayen MR, Jinno M, Kirshenbaum LA et al (2007) Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ 14:146–157
-
(2007)
Cell Death Differ
, vol.14
, pp. 146-157
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Logue, S.E.3
Sayen, M.R.4
Jinno, M.5
Kirshenbaum, L.A.6
-
40
-
-
0029753768
-
Genetic instability induced by the tumor microenvironment
-
PID: 8971187, COI: 1:CAS:528:DyaK2sXjtlGq
-
Reynolds TY, Rockwell S, Glazer PM (1996) Genetic instability induced by the tumor microenvironment. Cancer Res 56:5754–5757
-
(1996)
Cancer Res
, vol.56
, pp. 5754-5757
-
-
Reynolds, T.Y.1
Rockwell, S.2
Glazer, P.M.3
-
41
-
-
68149147330
-
BNIP3 subfamily BH3-only proteins—mitochondrial stress sensors in normal and pathological functions
-
PID: 19641497, COI: 1:CAS:528:DC%2BD1MXpt1Wgurs%3D
-
Chinnadurai G, Vijayalingam S, Gibson Spencer B (2008) BNIP3 subfamily BH3-only proteins—mitochondrial stress sensors in normal and pathological functions. Oncogene 27(Suppl 1):S114–S127
-
(2008)
Oncogene
, vol.27
, pp. S114-S127
-
-
Chinnadurai, G.1
Vijayalingam, S.2
Gibson, S.B.3
-
42
-
-
4143106872
-
BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in nonsmall cell lung cancer
-
PID: 15328198, COI: 1:CAS:528:DC%2BD2cXmvFSlur8%3D
-
Giatromanolaki A, Koukourakis MI, Sowter HM, Sivridis E, Gibson S, Gatter KC et al (2004) BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in nonsmall cell lung cancer. Clin Cancer Res 10:5566–5571
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5566-5571
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sowter, H.M.3
Sivridis, E.4
Gibson, S.5
Gatter, K.C.6
-
43
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
PID: 12879018, COI: 1:CAS:528:DC%2BD3sXls1GjtLs%3D
-
Kothari S, Cizeau J, McMillan-Ward E, Israels SJ, Bailes M, Ens K et al (2003) BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22:4734–4744
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
McMillan-Ward, E.3
Israels, S.J.4
Bailes, M.5
Ens, K.6
-
44
-
-
21744434389
-
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
-
PID: 15856026, COI: 1:CAS:528:DC%2BD2MXlsVWmt7Y%3D
-
Erkan M, Kleeff J, Esposito I, Giese T, Ketterer K, Buchler MW et al (2005) Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. Oncogene 24:4421–4432
-
(2005)
Oncogene
, vol.24
, pp. 4421-4432
-
-
Erkan, M.1
Kleeff, J.2
Esposito, I.3
Giese, T.4
Ketterer, K.5
Buchler, M.W.6
-
45
-
-
3442888541
-
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
-
PID: 15289340, COI: 1:CAS:528:DC%2BD2cXmtF2murg%3D
-
Okami J, Simeone DM, Logsdon CD (2004) Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. Cancer Res 64:5338–5346
-
(2004)
Cancer Res
, vol.64
, pp. 5338-5346
-
-
Okami, J.1
Simeone, D.M.2
Logsdon, C.D.3
-
46
-
-
20444437669
-
Upregulation of BNIP3 by 5-aza-2′-deoxycytidine sensitizes pancreatic cancer cells to hypoxia mediated cell death
-
PID: 15942716, COI: 1:CAS:528:DC%2BD2MXlslGmtrw%3D
-
Abe T, Toyota M, Suzuki H, Murai M, Akino K, Ueno M et al (2005) Upregulation of BNIP3 by 5-aza-2′-deoxycytidine sensitizes pancreatic cancer cells to hypoxia mediated cell death. J Gastroenterol 40:504–510
-
(2005)
J Gastroenterol
, vol.40
, pp. 504-510
-
-
Abe, T.1
Toyota, M.2
Suzuki, H.3
Murai, M.4
Akino, K.5
Ueno, M.6
-
47
-
-
19944433480
-
Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer
-
PID: 15709167, COI: 1:CAS:528:DC%2BD2MXht1ynsbg%3D
-
Murai M, Toyota M, Suzuki H, Satoh A, Sasaki Y, Akino K et al (2005) Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer. Clin Cancer Res 11:1021–1027
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1021-1027
-
-
Murai, M.1
Toyota, M.2
Suzuki, H.3
Satoh, A.4
Sasaki, Y.5
Akino, K.6
-
48
-
-
33645239843
-
A potential molecular link between aerobic glycolysis and cancer
-
PID: 16479166, COI: 1:CAS:528:DC%2BD28XkslaqtL0%3D
-
Manka D, Millhorn DE (2006) A potential molecular link between aerobic glycolysis and cancer. Cell Cycle 5:343–344
-
(2006)
Cell Cycle
, vol.5
, pp. 343-344
-
-
Manka, D.1
Millhorn, D.E.2
-
49
-
-
66349121718
-
Hypoxia-induced Autophagy is mediated through HIF-induction of BNIP3 and BNIP3L via their BH3-domains
-
PID: 19273585, COI: 1:CAS:528:DC%2BD1MXlvFSqu70%3D
-
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouysségur J, Mazure NM (2009) Hypoxia-induced Autophagy is mediated through HIF-induction of BNIP3 and BNIP3L via their BH3-domains. Mol Cell Biol 29:2570–2581
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouysségur, J.6
Mazure, N.M.7
-
50
-
-
69449107689
-
Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia
-
PID: 19587545
-
Mazure Nathalie M, Pouysségur J (2009) Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia. Autophagy 5(6):868–869
-
(2009)
Autophagy
, vol.5
, Issue.6
, pp. 868-869
-
-
Mazure, N.M.1
Pouysségur, J.2
-
51
-
-
34848851131
-
Regulation of apoptosis in fibroblast-like synoviocytes by the hypoxia-induced Bcl-2 family member Bcl-2/adenovirus E1B 19-kd protein-interacting protein 3
-
PID: 17763440, COI: 1:CAS:528:DC%2BD2sXht1GgtbzN
-
Kammouni W, Wong K, Ma G, Firestein GS, Gibson SB, El-Gabalawy HS (2007) Regulation of apoptosis in fibroblast-like synoviocytes by the hypoxia-induced Bcl-2 family member Bcl-2/adenovirus E1B 19-kd protein-interacting protein 3. Arthritis Rheum 56:2854–2863
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2854-2863
-
-
Kammouni, W.1
Wong, K.2
Ma, G.3
Firestein, G.S.4
Gibson, S.B.5
El-Gabalawy, H.S.6
-
52
-
-
1242314873
-
Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus
-
PID: 14972662, COI: 1:CAS:528:DC%2BD2cXht1yrs78%3D
-
Schmidt-Kastner R, Aguirre-Chen C, Kietzmann T, Saul I, Busto R, Ginsberg MD (2004) Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus. Brain Res 1001:133–142
-
(2004)
Brain Res
, vol.1001
, pp. 133-142
-
-
Schmidt-Kastner, R.1
Aguirre-Chen, C.2
Kietzmann, T.3
Saul, I.4
Busto, R.5
Ginsberg, M.D.6
-
53
-
-
34247572412
-
BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia
-
PID: 17379825, COI: 1:CAS:528:DC%2BD2sXktlSmsrY%3D
-
Zhang Z, Yang X, Zhang S, Ma X, Kong J (2007) BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia. Stroke 38:1606–1613
-
(2007)
Stroke
, vol.38
, pp. 1606-1613
-
-
Zhang, Z.1
Yang, X.2
Zhang, S.3
Ma, X.4
Kong, J.5
-
54
-
-
84897390838
-
BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton
-
Maes H, Van Eygen S, Krysko DV, Vandenabeele P, Nys K, Rillaerts K, Garg AD, Verfaillie T, Agostinis P (2014) BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton. Cell Death Dis 13(5):e1127
-
(2014)
Cell Death Dis
, vol.13
, Issue.5
, pp. e1127
-
-
Maes, H.1
Van Eygen, S.2
Krysko, D.V.3
Vandenabeele, P.4
Nys, K.5
Rillaerts, K.6
Garg, A.D.7
Verfaillie, T.8
Agostinis, P.9
-
55
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
PID: 12042769, COI: 1:CAS:528:DC%2BD38XksFOmsrw%3D
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415–428
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
56
-
-
0842278570
-
Epigenetic changes in colorectal cancer
-
PID: 15000147, COI: 1:CAS:528:DC%2BD3sXnsFansr0%3D
-
Kondo Y, Issa JP (2004) Epigenetic changes in colorectal cancer. Cancer Metastasis Rev 23:29–39
-
(2004)
Cancer Metastasis Rev
, vol.23
, pp. 29-39
-
-
Kondo, Y.1
Issa, J.P.2
-
57
-
-
7944230161
-
Epigenetic silencing mediated by CpG island methylation: Potential as a therapeutic target and as a biomarker
-
PID: 15533764, COI: 1:CAS:528:DC%2BD2cXpsVOksr4%3D
-
Teodoridis JM, Strathdee G, Brown R (2004) Epigenetic silencing mediated by CpG island methylation: potential as a therapeutic target and as a biomarker. Drug Resist Updat 7:267–278
-
(2004)
Drug Resist Updat
, vol.7
, pp. 267-278
-
-
Teodoridis, J.M.1
Strathdee, G.2
Brown, R.3
-
58
-
-
32944481037
-
Chemical genomic screening for methylation- silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray
-
PID: 16367923, COI: 1:CAS:528:DC%2BD28Xht1Kqtro%3D
-
Yamashita S, Tsujino Y, Moriguchi K et al (2006) Chemical genomic screening for methylation- silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray. Cancer Sci 97:64–71
-
(2006)
Cancer Sci
, vol.97
, pp. 64-71
-
-
Yamashita, S.1
Tsujino, Y.2
Moriguchi, K.3
-
59
-
-
34848881905
-
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma
-
PID: 17717605, COI: 1:CAS:528:DC%2BD2sXhtVCms7nE
-
Calvisi DF, Ladu S, Gorden A, Farina M, Lee JS, Conner EA et al (2007) Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma. J Clin Invest 117:2713–2722
-
(2007)
J Clin Invest
, vol.117
, pp. 2713-2722
-
-
Calvisi, D.F.1
Ladu, S.2
Gorden, A.3
Farina, M.4
Lee, J.S.5
Conner, E.A.6
-
60
-
-
0033984094
-
BNIP3heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3(BH) domain at both mitochondrial and nonmitochondrial sites
-
PID: 10625696, COI: 1:CAS:528:DC%2BD3cXntleksA%3D%3D
-
Ray R, Chen G, Vande Velde C et al (2000) BNIP3heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3(BH) domain at both mitochondrial and nonmitochondrial sites. J Biol Chem 275:1439–1448
-
(2000)
J Biol Chem
, vol.275
, pp. 1439-1448
-
-
Ray, R.1
Chen, G.2
Vande Velde, C.3
-
61
-
-
1342333155
-
Expression of the cell death gene BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade
-
PID: 14648660, COI: 1:CAS:528:DC%2BD2cXlsVGmsQ%3D%3D
-
Sowter HM, Ferguson M, Pym C et al (2003) Expression of the cell death gene BNip3 and NIX in ductal carcinoma in situ of the breast; correlation of BNip3 levels with necrosis and grade. J Pathol 201:573–580
-
(2003)
J Pathol
, vol.201
, pp. 573-580
-
-
Sowter, H.M.1
Ferguson, M.2
Pym, C.3
-
62
-
-
20244368980
-
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours
-
PID: 15756280, COI: 1:CAS:528:DC%2BD2MXisVyisb0%3D
-
Murai M, Toyota M, Satoh A, Suzuki H, Akino K, Mita H et al (2005) Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours. Br J Cancer 92:1165–1172
-
(2005)
Br J Cancer
, vol.92
, pp. 1165-1172
-
-
Murai, M.1
Toyota, M.2
Satoh, A.3
Suzuki, H.4
Akino, K.5
Mita, H.6
-
63
-
-
0035542974
-
Methyl CpG-binding proteins and transcriptional repression
-
PID: 11746232, COI: 1:CAS:528:DC%2BD38XksFOluw%3D%3D
-
Wade PA (2001) Methyl CpG-binding proteins and transcriptional repression. BioEssays 23:1131–1137
-
(2001)
BioEssays
, vol.23
, pp. 1131-1137
-
-
Wade, P.A.1
-
64
-
-
0035158704
-
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
-
PID: 11137995, COI: 1:CAS:528:DC%2BD3MXis1yksw%3D%3D
-
Jackson-Grusby L, Beard C, Possemato R et al (2001) Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet 27:31–39
-
(2001)
Nat Genet
, vol.27
, pp. 31-39
-
-
Jackson-Grusby, L.1
Beard, C.2
Possemato, R.3
-
65
-
-
79960595659
-
Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway
-
PID: 21573703, COI: 1:CAS:528:DC%2BC3MXns12ktb8%3D
-
An HJ, Lee H, Paik SG (2011) Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway. Mol Cells 31(6):579–583
-
(2011)
Mol Cells
, vol.31
, Issue.6
, pp. 579-583
-
-
An, H.J.1
Lee, H.2
Paik, S.G.3
-
66
-
-
84892800436
-
GCPII modulates oxidative stress and prostate cancer susceptibility through changes in methylation of RASSF1, BNIP3, GSTP1 and Ec-SOD
-
PID: 23979608, COI: 1:CAS:528:DC%2BC3sXhtlCgtbvK
-
Divyya S, Naushad SM, Murthy PV, Reddy ChR, Kutala VK (2013) GCPII modulates oxidative stress and prostate cancer susceptibility through changes in methylation of RASSF1, BNIP3, GSTP1 and Ec-SOD. Mol Biol Rep 40(10):5541–5550
-
(2013)
Mol Biol Rep
, vol.40
, Issue.10
, pp. 5541-5550
-
-
Divyya, S.1
Naushad, S.M.2
Murthy, P.V.3
Reddy, C.R.4
Kutala, V.K.5
-
67
-
-
85027953973
-
Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast
-
PID: 21987236, COI: 1:CAS:528:DC%2BC3MXhs1OqsrzF
-
Naushad SM, Prayaga A, Digumarti RR, Gottumukkala SR, Kutala VK (2012) Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) expression is epigenetically regulated by one-carbon metabolism in invasive duct cell carcinoma of breast. Mol Cell Biochem 361(1–2):189–195
-
(2012)
Mol Cell Biochem
, vol.361
, Issue.1-2
, pp. 189-195
-
-
Naushad, S.M.1
Prayaga, A.2
Digumarti, R.R.3
Gottumukkala, S.R.4
Kutala, V.K.5
-
68
-
-
84871975827
-
Oxidative stress in coronary artery disease: Epigenetic perspective
-
PID: 23160801, COI: 1:CAS:528:DC%2BC3sXnsVyh
-
Lakshmi SV, Naushad SM, Reddy CA, Saumya K, Rao DS, Kotamraju S, Kutala VK (2013) Oxidative stress in coronary artery disease: epigenetic perspective. Mol Cell Biochem 374(1–2):203–211
-
(2013)
Mol Cell Biochem
, vol.374
, Issue.1-2
, pp. 203-211
-
-
Lakshmi, S.V.1
Naushad, S.M.2
Reddy, C.A.3
Saumya, K.4
Rao, D.S.5
Kotamraju, S.6
Kutala, V.K.7
-
69
-
-
84898007849
-
Mitochondrial-targeted curcuminoids: A strategy to enhance bioavailability and anticancer efficacy of curcumin
-
PID: 24622734
-
Reddy CA, Somepalli V, Golakoti T, Kanugula AK, Karnewar S, Rajendiran K, Vasagiri N, Prabhakar S, Kuppusamy P, Kotamraju S, Kutala VK (2014) Mitochondrial-targeted curcuminoids: a strategy to enhance bioavailability and anticancer efficacy of curcumin. PLoS One 9(3):e89351
-
(2014)
PLoS One
, vol.9
, Issue.3
, pp. e89351
-
-
Reddy, C.A.1
Somepalli, V.2
Golakoti, T.3
Kanugula, A.K.4
Karnewar, S.5
Rajendiran, K.6
Vasagiri, N.7
Prabhakar, S.8
Kuppusamy, P.9
Kotamraju, S.10
Kutala, V.K.11
-
70
-
-
84905158252
-
Molecular insights into the association of obesity with breast cancer risk: Relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes
-
PID: 24676543, COI: 1:CAS:528:DC%2BC2cXltleltrw%3D
-
Naushad SM, Hussain T, Al-Attas OS, Prayaga AA, Digumarti RR, Gottumukkala SR, Kutala VK (2014) Molecular insights into the association of obesity with breast cancer risk: relevance to xenobiotic metabolism and CpG island methylation of tumor suppressor genes. Mol Cell Biochem 392(1–2):273–280
-
(2014)
Mol Cell Biochem
, vol.392
, Issue.1-2
, pp. 273-280
-
-
Naushad, S.M.1
Hussain, T.2
Al-Attas, O.S.3
Prayaga, A.A.4
Digumarti, R.R.5
Gottumukkala, S.R.6
Kutala, V.K.7
|