A novel cinnamide YLT26 induces breast cancer cells apoptosis via ROS-mitochondrial apoptotic pathway in vitro and inhibits lung metastasis in vivo

Cellular Physiology and Biochemistry

Volumn 34, Issue 6, 2014, Pages 1863-1876

  Xiong, Ying ^a   Ye, Tinghong ^a   Wang, Mengyao ^b   Xia, Yong ^a   Wang, Ningyu ^a   Song, Xuejiao ^a   Wang, Fengtian ^b   Liu, Li ^b   Zhu, Yongxia ^a   Yang, Fangfang ^a   Wei, Yuquan ^a   Yu, Luoting ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Breast cancer; MDSCs; Metastasis; ROS; YLT26

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 9; CD11B ANTIGEN; N [4 N (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL)PHENYL] 3 (3,4,5 TRIMETHOXYPHENYL)ACRYLAMIDE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANILIDE; CINNAMIC ACID DERIVATIVE; N-(4-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)PHENYL)-3-(3,4,5-TRIMETHOXYPHENYL)ACRYLAMIDE; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CELL INFILTRATION; CELL PROLIFERATION; CELL VIABILITY; CLINICAL EVALUATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG INFILTRATE; LUNG METASTASIS; LUNG PARENCHYMA; MCF 7 CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BREAST NEOPLASMS; DRUG EFFECTS; GENE EXPRESSION REGULATION; LUNG NEOPLASMS; METABOLISM; PATHOLOGY; SECONDARY; TUMOR CELL LINE;

MUS;

ANILIDES; ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CINNAMATES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM PROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84917706039     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366385     Document Type: Article

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