The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Ye, Tinghong ^a   Xiong, Ying ^a   Yan, Yupeng ^a,b   Xia, Yong ^a   Song, Xuejiao ^a   Liu, Li ^a,b   Li, Deliang ^a   Wang, Ningyu ^a   Zhang, Lidan ^a,b   Zhu, Yongxia ^a   Zeng, Jun ^a   Wei, Yuquan ^a   Yu, Luoting ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FOCAL ADHESION KINASE; KI 67 ANTIGEN; NICLOSAMIDE; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; SURVIVIN; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER MODEL; CANCER TISSUE; CAPILLARY DENSITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; ENZYME ACTIVATION; ENZYME DEGRADATION; FEMALE; GROWTH INHIBITION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN PHOSPHORYLATION; RISK BENEFIT ANALYSIS; SUPPRESSOR CELL; TUMOR INVASION; WESTERN BLOTTING;

ANIMALS; ANTHELMINTICS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LUNG NEOPLASMS; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; NICLOSAMIDE; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896963899     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085887     Document Type: Article

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