메뉴 건너뛰기




Volumn 472, Issue 4, 2014, Pages 1318-1328

Novel microhydroxyapatite particles in a collagen scaffold: A bioactive bone void filler?

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; HYDROXYAPATITE; MICROHYDROXYAPATITE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; UNCLASSIFIED DRUG;

EID: 84896390054     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-013-3438-0     Document Type: Article
Times cited : (81)

References (47)
  • 1
    • 0035876414 scopus 로고    scopus 로고
    • Evaluation of ceramics composed of different hydroxyapatite to tricalcium phosphate ratios as carriers for rhBMP-2
    • 11374466 10.1016/S0142-9612(00)00322-7
    • Alam MI, Asahina I, Ohmamiuda K, Takahashi K, Yokota S, Enomoto S. Evaluation of ceramics composed of different hydroxyapatite to tricalcium phosphate ratios as carriers for rhBMP-2. Biomaterials. 2001;22:1643-1651.
    • (2001) Biomaterials. , vol.22 , pp. 1643-1651
    • Alam, M.I.1    Asahina, I.2    Ohmamiuda, K.3    Takahashi, K.4    Yokota, S.5    Enomoto, S.6
  • 2
    • 0033961003 scopus 로고    scopus 로고
    • Bone graft materials: An overview of the basic science
    • 10693546 10.1097/00003086-200002000-00003
    • Bauer TW, Muschler GF. Bone graft materials: an overview of the basic science. Clin Orthop Relat Res. 2000;371:10-27.
    • (2000) Clin Orthop Relat Res. , vol.371 , pp. 10-27
    • Bauer, T.W.1    Muschler, G.F.2
  • 3
    • 0033954803 scopus 로고    scopus 로고
    • The use of rhBMP-2 in interbody fusion cages: Definitive evidence of osteoinduction in humans: A preliminary report
    • 10.1097/00007632-200002010-00020
    • Boden SD, Zdeblick TA, Sandhu HS, Heim SE. The use of rhBMP-2 in interbody fusion cages: definitive evidence of osteoinduction in humans: a preliminary report. Spine (Phila Pa 1976). 2000;25:376-381.
    • (2000) Spine (Phila Pa 1976). , vol.25 , pp. 376-381
    • Boden, S.D.1    Zdeblick, T.A.2    Sandhu, H.S.3    Heim, S.E.4
  • 4
    • 84856480411 scopus 로고    scopus 로고
    • Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cell-mediated bone formation
    • 22213347 10.1002/adma.201103828
    • Curtin CM, Cunniffe GM, Lyons FG, Bessho K, Dickson GR, Duffy GP, O'Brien FJ. Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cell-mediated bone formation. Adv Mater. 2012;24:749-754.
    • (2012) Adv Mater. , vol.24 , pp. 749-754
    • Curtin, C.M.1    Cunniffe, G.M.2    Lyons, F.G.3    Bessho, K.4    Dickson, G.R.5    Duffy, G.P.6    O'Brien, F.J.7
  • 5
    • 84896391201 scopus 로고    scopus 로고
    • Department of Health and Human Services, US. Agency for Healthcare Research and Quality report Accessed 05/12/2011
    • Department of Health and Human Services, US. Agency for Healthcare Research and Quality report. Bone Morphogenetic Protein: The State of the Evidence for On-Label and Off-Label Use. Available at: http://www.ahrq.gov/ clinic/ta/comments/boneprotein/. Accessed 05/12/2011.
    • Bone Morphogenetic Protein: The State of the Evidence for On-Label and Off-Label Use
  • 6
    • 78649490328 scopus 로고    scopus 로고
    • FDA Centers for Devices and Radiological Health. Corrspondence to RW Treharne and Premarket Approval Application (PMS) Supplement. Re: P000058 Accessed May 12, 2011
    • FDA Centers for Devices and Radiological Health. Corrspondence to RW Treharne and Premarket Approval Application (PMS) Supplement. Re: P000058. InFUSE™ Bone Graft/LT-CAGE™ Lumbar Tapered Fusion Device. Available at: http://www.accessdata.fda.gov/cdrh-docs/pdf/P000058a.pdf. Accessed May 12, 2011.
    • InFUSE™ Bone Graft/LT-CAGE™ Lumbar Tapered Fusion Device
  • 7
    • 84873546382 scopus 로고    scopus 로고
    • FDA Centers for Devices and Radiological Health Accessed May 12, 2011
    • FDA Centers for Devices and Radiological Health. Summary of Safety and Effectiveness Data. Available at: http://www.accessdata.fda.gov/cdrh-docs/pdf/ P000058b.pdf. Accessed May 12, 2011.
    • Summary of Safety and Effectiveness Data
  • 9
    • 84896401407 scopus 로고    scopus 로고
    • FDA. Centers for Devices and Radiological Health Accessed May 12, 2011
    • FDA. Centers for Devices and Radiological Health. Correspondence to D Ellis and Premarket Approval for INFUSE® bone graft. Available at: http://www.accessdata.fda.gov/cdrh-docs/pdf/p000054a.pdf. Accessed May 12, 2011.
    • Correspondence to D Ellis and Premarket Approval for INFUSE® Bone Graft
  • 10
    • 77952985135 scopus 로고    scopus 로고
    • Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions
    • 20495420 10.1227/01.NEU.0000369517.21018.F2 discussion 1049
    • Garrett MP, Kakarla UK, Porter RW, Sonntag VK. Formation of painful seroma and edema after the use of recombinant human bone morphogenetic protein-2 in posterolateral lumbar spine fusions. Neurosurgery. 2010;66:1044-1049; discussion 1049.
    • (2010) Neurosurgery. , vol.66 , pp. 1044-1049
    • Garrett, M.P.1    Kakarla, U.K.2    Porter, R.W.3    Sonntag, V.K.4
  • 11
    • 79952117387 scopus 로고    scopus 로고
    • Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagen-based scaffold for bone tissue regeneration
    • 20922667
    • Gleeson JP, Plunkett NA, O'Brien FJ. Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagen-based scaffold for bone tissue regeneration. Eur Cell Mater. 2010;20:218-230.
    • (2010) Eur Cell Mater. , vol.20 , pp. 218-230
    • Gleeson, J.P.1    Plunkett, N.A.2    O'Brien, F.J.3
  • 12
    • 65549105456 scopus 로고    scopus 로고
    • The effect of dehydrothermal treatment on the mechanical and structural properties of collagen-GAG scaffolds
    • 18431763 10.1002/jbm.a.31955
    • Haugh MG, Jaasma MJ, O'Brien FJ. The effect of dehydrothermal treatment on the mechanical and structural properties of collagen-GAG scaffolds. J Biomed Mater Res A. 2009;89:363-369.
    • (2009) J Biomed Mater Res A. , vol.89 , pp. 363-369
    • Haugh, M.G.1    Jaasma, M.J.2    O'Brien, F.J.3
  • 13
    • 13944255093 scopus 로고    scopus 로고
    • In vivo degradation of porous poly(propylene fumarate)/poly(DL-lactic-co- glycolic acid) composite scaffolds
    • 15722131 10.1016/j.biomaterials.2004.11.039
    • Hedberg EL, Kroese-Deutman HC, Shih CK, Crowther RS, Carney DH, Mikos AG, Jansen JA. In vivo degradation of porous poly(propylene fumarate)/poly(DL- lactic-co-glycolic acid) composite scaffolds. Biomaterials. 2005;26:4616-4623.
    • (2005) Biomaterials. , vol.26 , pp. 4616-4623
    • Hedberg, E.L.1    Kroese-Deutman, H.C.2    Shih, C.K.3    Crowther, R.S.4    Carney, D.H.5    Mikos, A.G.6    Jansen, J.A.7
  • 14
    • 70349263153 scopus 로고    scopus 로고
    • Bone-graft substitutes in orthopaedic surgery
    • Fellows at WHP
    • Jahangir AA, Nunley RM, Mehta S, Sharan A; Fellows at WHP. Bone-graft substitutes in orthopaedic surgery. AAOS Now. 2008;2:1-5.
    • (2008) AAOS Now. , vol.2 , pp. 1-5
    • Jahangir, A.A.1    Nunley, R.M.2    Mehta, S.3    Sharan, A.4
  • 15
    • 17844400927 scopus 로고    scopus 로고
    • Porosity of 3D biomaterial scaffolds and osteogenesis
    • 15860204 10.1016/j.biomaterials.2005.02.002
    • Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005;26:5474-5491.
    • (2005) Biomaterials. , vol.26 , pp. 5474-5491
    • Karageorgiou, V.1    Kaplan, D.2
  • 17
    • 20444410357 scopus 로고    scopus 로고
    • Ectopic bone formation by microporous calcium phosphate ceramic particles in sheep muscles
    • 15869915 10.1016/j.bone.2005.02.017
    • Le Nihouannen D, Daculsi G, Saffarzadeh A, Gauthier O, Delplace S, Pilet P, Layrolle P. Ectopic bone formation by microporous calcium phosphate ceramic particles in sheep muscles. Bone. 2005;36:1086-1093.
    • (2005) Bone. , vol.36 , pp. 1086-1093
    • Le Nihouannen, D.1    Daculsi, G.2    Saffarzadeh, A.3    Gauthier, O.4    Delplace, S.5    Pilet, P.6    Layrolle, P.7
  • 18
    • 57349168055 scopus 로고    scopus 로고
    • Calcium phosphate-based osteoinductive materials
    • 19006399 10.1021/cr800427g
    • LeGeros RZ. Calcium phosphate-based osteoinductive materials. Chem Rev. 2008;108:4742-4753.
    • (2008) Chem Rev. , vol.108 , pp. 4742-4753
    • Legeros, R.Z.1
  • 19
    • 77957943567 scopus 로고    scopus 로고
    • The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs
    • 20863559 10.1016/j.biomaterials.2010.08.056
    • Lyons FG, Al-Munajjed AA, Kieran SM, Toner ME, Murphy CM, Duffy GP, O'Brien FJ. The healing of bony defects by cell-free collagen-based scaffolds compared to stem cell-seeded tissue engineered constructs. Biomaterials. 2010;31:9232-9243.
    • (2010) Biomaterials. , vol.31 , pp. 9232-9243
    • Lyons, F.G.1    Al-Munajjed, A.A.2    Kieran, S.M.3    Toner, M.E.4    Murphy, C.M.5    Duffy, G.P.6    O'Brien, F.J.7
  • 20
    • 0037102590 scopus 로고    scopus 로고
    • Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications
    • 10.1097/00007632-200208151-00014
    • McKay B, Sandhu HS. Use of recombinant human bone morphogenetic protein-2 in spinal fusion applications. Spine (Phila Pa 1976). 2002;27(16 suppl 1):S66-85.
    • (2002) Spine (Phila Pa 1976). , vol.27 , Issue.16 SUPPL. 1
    • McKay, B.1    Sandhu, H.S.2
  • 21
    • 70449088920 scopus 로고    scopus 로고
    • The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering
    • 19819008 10.1016/j.biomaterials.2009.09.063
    • Murphy CM, Haugh MG, O'Brien FJ. The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. Biomaterials. 2010;31:461-466.
    • (2010) Biomaterials. , vol.31 , pp. 461-466
    • Murphy, C.M.1    Haugh, M.G.2    O'Brien, F.J.3
  • 22
    • 0242438580 scopus 로고    scopus 로고
    • Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds
    • 14615173 10.1016/S0142-9612(03)00630-6
    • O'Brien FJ, Harley BA, Yannas IV, Gibson L. Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds. Biomaterials. 2004;25:1077-1086.
    • (2004) Biomaterials. , vol.25 , pp. 1077-1086
    • O'Brien, F.J.1    Harley, B.A.2    Yannas, I.V.3    Gibson, L.4
  • 23
    • 3242707718 scopus 로고    scopus 로고
    • The effect of pore size on cell adhesion in collagen-GAG scaffolds
    • 15275817 10.1016/j.biomaterials.2004.02.052
    • O'Brien FJ, Harley BA, Yannas IV, Gibson LJ. The effect of pore size on cell adhesion in collagen-GAG scaffolds. Biomaterials. 2005;26:433-441.
    • (2005) Biomaterials. , vol.26 , pp. 433-441
    • O'Brien, F.J.1    Harley, B.A.2    Yannas, I.V.3    Gibson, L.J.4
  • 25
    • 0033065993 scopus 로고    scopus 로고
    • Bone repair techniques, bone graft, and bone graft substitutes
    • 10101312 10.1097/00003086-199903000-00010
    • Perry CR. Bone repair techniques, bone graft, and bone graft substitutes. Clin Orthop Relat Res. 1999;360:71-86.
    • (1999) Clin Orthop Relat Res. , vol.360 , pp. 71-86
    • Perry, C.R.1
  • 26
    • 84962743334 scopus 로고    scopus 로고
    • Bone morphogenetic protein: The state of the evidence of on-label and off-label use
    • Accessed May 12, 2011
    • Ratko TA, Belinson SE, Samson DJ, Bonnell C, Ziegler KM, Aronson N. Bone morphogenetic protein: the state of the evidence of on-label and off-label use. Technology Assessment Report. Available at: http://www.cms.gov/ DeterminationProcess/downloads/id75ta.pdf?bcsi-scan-9CF786ACA806128D= 0&bcsi-scan-filename=id75ta.pdf. Accessed May 12, 2011.
    • Technology Assessment Report
    • Ratko, T.A.1    Belinson, S.E.2    Samson, D.J.3    Bonnell, C.4    Ziegler, K.M.5    Aronson, N.6
  • 27
    • 0344306399 scopus 로고    scopus 로고
    • Performance of degradable composite bone repair products made via three-dimensional fabrication techniques
    • 12888998 10.1002/jbm.a.10582
    • Roy TD, Simon JL, Ricci JL, Rekow ED, Thompson VP, Parsons JR. Performance of degradable composite bone repair products made via three-dimensional fabrication techniques. J Biomed Mater Res A. 2003;66:283-291.
    • (2003) J Biomed Mater Res A. , vol.66 , pp. 283-291
    • Roy, T.D.1    Simon, J.L.2    Ricci, J.L.3    Rekow, E.D.4    Thompson, V.P.5    Parsons, J.R.6
  • 28
    • 68249153278 scopus 로고    scopus 로고
    • Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces
    • 18655137 10.1002/jbm.a.31745
    • Schuessele A, Mayr H, Tessmar J, Goepferich A. Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces. J Biomed Mater Res A. 2009;90:959-971.
    • (2009) J Biomed Mater Res A. , vol.90 , pp. 959-971
    • Schuessele, A.1    Mayr, H.2    Tessmar, J.3    Goepferich, A.4
  • 29
    • 0034026950 scopus 로고    scopus 로고
    • Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model
    • 10815831 10.1002/jor.1100180218
    • Sciadini MF, Johnson KD. Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model. J Orthop Res. 2000;18:289-302.
    • (2000) J Orthop Res. , vol.18 , pp. 289-302
    • Sciadini, M.F.1    Johnson, K.D.2
  • 30
    • 0037102139 scopus 로고    scopus 로고
    • Bone morphogenetic protein delivery systems
    • 10.1097/00007632-200208151-00005
    • Seeherman H, Wozney J, Li R. Bone morphogenetic protein delivery systems. Spine (Phila Pa 1976). 2002;27(16 suppl 1):S16-23.
    • (2002) Spine (Phila Pa 1976). , vol.27 , Issue.16 SUPPL. 1
    • Seeherman, H.1    Wozney, J.2    Li, R.3
  • 31
    • 33645508135 scopus 로고    scopus 로고
    • Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion
    • 10.1097/01.brs.0000201424.27509.72
    • Shields LB, Raque GH, Glassman SD, Campbell M, Vitaz T, Harpring J, Shields CB. Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion. Spine (Phila Pa 1976). 2006;31:542-547.
    • (2006) Spine (Phila Pa 1976). , vol.31 , pp. 542-547
    • Shields, L.B.1    Raque, G.H.2    Glassman, S.D.3    Campbell, M.4    Vitaz, T.5    Harpring, J.6    Shields, C.B.7
  • 32
    • 84861531600 scopus 로고    scopus 로고
    • Assessment of MASTERGRAFT PUTTY as a graft extender in a rabbit posterolateral fusion model
    • 10.1097/BRS.0b013e31824444c4
    • Smucker JD, Petersen EB, Fredericks DC. Assessment of MASTERGRAFT PUTTY as a graft extender in a rabbit posterolateral fusion model. Spine (Phila Pa 1976). 2012;37:1017-1021.
    • (2012) Spine (Phila Pa 1976). , vol.37 , pp. 1017-1021
    • Smucker, J.D.1    Petersen, E.B.2    Fredericks, D.C.3
  • 33
    • 59349120485 scopus 로고    scopus 로고
    • The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering
    • 19627824 10.1016/j.jmbbm.2008.08.007
    • Tierney CM, Haugh MG, Liedl J, Mulcahy F, Hayes B, O'Brien FJ. The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen-GAG scaffolds for bone tissue engineering. J Mech Behav Biomed Mater. 2009;2:202-209.
    • (2009) J Mech Behav Biomed Mater. , vol.2 , pp. 202-209
    • Tierney, C.M.1    Haugh, M.G.2    Liedl, J.3    Mulcahy, F.4    Hayes, B.5    O'Brien, F.J.6
  • 34
    • 0019501769 scopus 로고
    • Bridging of large chronic osteoperiosteal gaps by allogeneic decalcified bone matrix implants in rabbits
    • 7277535 10.1097/00005373-198110000-00011
    • Tuli SM, Gupta KB. Bridging of large chronic osteoperiosteal gaps by allogeneic decalcified bone matrix implants in rabbits. J Trauma. 1981;21:894-898.
    • (1981) J Trauma. , vol.21 , pp. 894-898
    • Tuli, S.M.1    Gupta, K.B.2
  • 35
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • 5319761 10.1126/science.150.3698.893
    • Urist MR. Bone: formation by autoinduction. Science. 1965;150:893-899.
    • (1965) Science. , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 36
    • 67651085493 scopus 로고    scopus 로고
    • Transforaminal interbody fusion and the "off label" use of recombinant human bone morphogenetic protein-2
    • 19622413 10.1016/j.spinee.2009.05.014
    • Vaidya R. Transforaminal interbody fusion and the "off label" use of recombinant human bone morphogenetic protein-2. Spine J. 2009;9:667-669.
    • (2009) Spine J. , vol.9 , pp. 667-669
    • Vaidya, R.1
  • 37
    • 84873978765 scopus 로고    scopus 로고
    • Hydroxyapatite nanoparticle reinforced peptide amphiphile nanomatrix enhances the osteogenic differentiation of mesenchymal stem cells by compositional ratios
    • 3462224 22842043 10.1016/j.actbio.2012.07.024
    • Vines JB, Lim DJ, Anderson JM, Jun HW. Hydroxyapatite nanoparticle reinforced peptide amphiphile nanomatrix enhances the osteogenic differentiation of mesenchymal stem cells by compositional ratios. Acta Biomater. 2012;8:4053-4063.
    • (2012) Acta Biomater. , vol.8 , pp. 4053-4063
    • Vines, J.B.1    Lim, D.J.2    Anderson, J.M.3    Jun, H.W.4
  • 38
    • 79953877788 scopus 로고    scopus 로고
    • Histologic evaluation of human alveolar sockets treated with an artificial bone substitute material
    • 21415629 10.1097/SCS.0b013e318208bacf
    • Wakimoto M, Ueno T, Hirata A, Iida S, Aghaloo T, Moy PK. Histologic evaluation of human alveolar sockets treated with an artificial bone substitute material. J Craniofac Surg. 2011;22:490-493.
    • (2011) J Craniofac Surg. , vol.22 , pp. 490-493
    • Wakimoto, M.1    Ueno, T.2    Hirata, A.3    Iida, S.4    Aghaloo, T.5    Moy, P.K.6
  • 39
    • 69249206554 scopus 로고    scopus 로고
    • On the nature of biomaterials
    • 19651435 10.1016/j.biomaterials.2009.07.027
    • Williams DF. On the nature of biomaterials. Biomaterials. 2009;30:5897-5909.
    • (2009) Biomaterials. , vol.30 , pp. 5897-5909
    • Williams, D.F.1
  • 40
    • 54449094771 scopus 로고    scopus 로고
    • Neurologic impairment from ectopic bone in the lumbar canal: A potential complication of off-label PLIF/TLIF use of bone morphogenetic protein-2 (BMP-2)
    • 18037352 10.1016/j.spinee.2007.06.014
    • Wong DA, Kumar A, Jatana S, Ghiselli G, Wong K. Neurologic impairment from ectopic bone in the lumbar canal: a potential complication of off-label PLIF/TLIF use of bone morphogenetic protein-2 (BMP-2). Spine J. 2008;8:1011-1018.
    • (2008) Spine J. , vol.8 , pp. 1011-1018
    • Wong, D.A.1    Kumar, A.2    Jatana, S.3    Ghiselli, G.4    Wong, K.5
  • 41
    • 0018841015 scopus 로고
    • Design of an artificial skin: I. Basic design principles
    • 6987234 10.1002/jbm.820140108
    • Yannas IV, Burke JF. Design of an artificial skin: I. Basic design principles. J Biomed Mater Res. 1980;14:65-81.
    • (1980) J Biomed Mater Res. , vol.14 , pp. 65-81
    • Yannas, I.V.1    Burke, J.F.2
  • 43
    • 0001031272 scopus 로고
    • Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin
    • 286593 2915988 10.1073/pnas.86.3.933
    • Yannas IV, Lee E, Orgill DP, Skrabut EM, Murphy GF. Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin. Proc Natl Acad Sci U S A. 1989;86:933-937.
    • (1989) Proc Natl Acad Sci U S A. , vol.86 , pp. 933-937
    • Yannas, I.V.1    Lee, E.2    Orgill, D.P.3    Skrabut, E.M.4    Murphy, G.F.5
  • 44
    • 0026757708 scopus 로고
    • The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2): A radiographic, histological, and biomechanical study in rats
    • 1378056
    • Yasko AW, Lane JM, Fellinger EJ, Rosen V, Wozney JM, Wang EA. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2): a radiographic, histological, and biomechanical study in rats. J Bone Joint Surg Am. 1992;74:659-670.
    • (1992) J Bone Joint Surg Am. , vol.74 , pp. 659-670
    • Yasko, A.W.1    Lane, J.M.2    Fellinger, E.J.3    Rosen, V.4    Wozney, J.M.5    Wang, E.A.6
  • 47
    • 0036973481 scopus 로고    scopus 로고
    • A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats
    • 15348676 10.1023/A:1021191432366
    • Yuan H, Van Den Doel M, Li S, Van Blitterswijk CA, De Groot K, De Bruijn JD. A comparison of the osteoinductive potential of two calcium phosphate ceramics implanted intramuscularly in goats. J Mater Sci Mater Med. 2002;13:1271-1275.
    • (2002) J Mater Sci Mater Med. , vol.13 , pp. 1271-1275
    • Yuan, H.1    Van Den Doel, M.2    Li, S.3    Van Blitterswijk, C.A.4    De Groot, K.5    De Bruijn, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.