Dual growth factor delivery from bilayered, biodegradable hydrogel composites for spatially-guided osteochondral tissue repair

Biomaterials

Volumn 35, Issue 31, 2014, Pages 8829-8839

  Lu, Steven ^a   Lam, Johnny ^a   Trachtenberg, Jordan E ^a   Lee, Esther J ^a   Seyednejad, Hajar ^a   van den Beucken, Jeroen J J P ^d   Tabata, Yasuhiko ^b   Wong, Mark E ^c   Jansen, John A ^d   Mikos, Antonios G ^a   Kasper, F Kurtis ^a  

^a Rice University   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS   (United States)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bone morphogenetic protein 2; Cartilage repair; Insulin like growth factor 1; Rabbit model; Subchondral bone

Indexed keywords

CARTILAGE; COMPUTERIZED TOMOGRAPHY; HYDROGELS; INSULIN; POLYETHYLENE GLYCOLS; PROTEINS; QUALITY CONTROL; SCAFFOLDS (BIOLOGY); TISSUE; TISSUE REGENERATION;

BIODEGRADABLE HYDROGELS; BONE MORPHOGENETIC PROTEIN-2; CARTILAGE REPAIR; INSULIN-LIKE GROWTH FACTOR-1; MEDIAL FEMORAL CONDYLE; MICRO COMPUTED TOMOGRAPHY (MICRO-CT); OLIGO(POLY(ETHYLENE GLYCOL)FUMARATE); RABBIT MODELS;

REPAIR;

GELATIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT SOMATOMEDIN C; TISSUE SCAFFOLD; BONE MORPHOGENETIC PROTEIN 2; FUMARIC ACID DERIVATIVE; HYDROGEL; MACROGOL DERIVATIVE; POLY(ETHYLENE GLYCOL FUMARATE); SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIODEGRADABILITY; BONE DENSITY; BONE GROWTH; BONE MASS; BONE REMODELING; CARTILAGE; CARTILAGE CELL; CHONDROGENESIS; CHONDROPATHY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; FEMUR CONDYLE; FIBROCARTILAGE; HISTOLOGY; HYALINE CARTILAGE; HYDROGEL; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RABBIT MODEL; TISSUE REPAIR; TRABECULAR BONE; ANIMAL; CHEMISTRY; DRUG EFFECTS; FEMUR; PATHOLOGY; PHYSIOLOGY; RABBIT; REGENERATION; TISSUE SCAFFOLD;

ORYCTOLAGUS CUNICULUS;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CARTILAGE; FEMUR; FUMARATES; HYDROGEL; INSULIN-LIKE GROWTH FACTOR I; MALE; POLYETHYLENE GLYCOLS; RABBITS; REGENERATION; TISSUE SCAFFOLDS;

EID: 84905496183     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.07.006     Document Type: Article

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