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Volumn 24, Issue 3, 2013, Pages 773-782

Bone morphogenic protein-2 (BMP-2) loaded hybrid coating on porous hydroxyapatite scaffolds for bone tissue engineering

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROPERTIES; BONE REGENERATION; BONE TISSUE ENGINEERING; CELLULAR RESPONSE; OSTEOBLASTIC CELLS; POROUS HYDROXYAPATITE; RELEASE BEHAVIORS; THERAPEUTIC AGENTS;

EID: 84876411058     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-012-4822-0     Document Type: Article
Times cited : (82)

References (42)
  • 1
    • 0041825765 scopus 로고    scopus 로고
    • Tissue regeneration based on growth factor release
    • 10.1089/10763270360696941 1:CAS:528:DC%2BD3sXnvF2lsLw%3D
    • Tabata Y. Tissue regeneration based on growth factor release. Tissue Eng. 2003;9:S5-15.
    • (2003) Tissue Eng. , vol.9
    • Tabata, Y.1
  • 2
    • 34848905498 scopus 로고    scopus 로고
    • Materials in particulate form for tissue engineering. 2. Applications in bone
    • Silva GA, Countinho OP, Ducheyne P, Reis RL. Materials in particulate form for tissue engineering. 2. Applications in bone. J Tissue Eng Reg Med. 2007; 1: 97-109.
    • (2007) J Tissue Eng Reg Med. , vol.1 , pp. 97-109
    • Silva, G.A.1    Countinho, O.P.2    Ducheyne, P.3    Reis, R.L.4
  • 3
    • 82855161293 scopus 로고    scopus 로고
    • Effects of osteogenic growth-factors on bone marrow stromal cell differentiation in a mineral-based delivery system
    • 10.1016/j.biomaterials.2011.09.052 1:CAS:528:DC%2BC3MXhsVWksr7L
    • Luong LN, Ramaswamy J, Kohn DH. Effects of osteogenic growth-factors on bone marrow stromal cell differentiation in a mineral-based delivery system. Biomaterials. 2012;33:283-94.
    • (2012) Biomaterials. , vol.33 , pp. 283-294
    • Luong, L.N.1    Ramaswamy, J.2    Kohn, D.H.3
  • 4
    • 73249127019 scopus 로고    scopus 로고
    • Bone tissue engineering: A review in bone biomimetics and drug delivery strategies
    • 1:CAS:528:DC%2BC3cXnslGg
    • Porter JR, Ruckh TT, Popat KC. Bone tissue engineering: a review in bone biomimetics and drug delivery strategies. Biotechnol Prog. 2009;25:1539-60.
    • (2009) Biotechnol Prog. , vol.25 , pp. 1539-1560
    • Porter, J.R.1    Ruckh, T.T.2    Popat, K.C.3
  • 5
    • 34249938497 scopus 로고    scopus 로고
    • Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering
    • 10.1016/j.addr.2007.03.016 1:CAS:528:DC%2BD2sXmtlShurc%3D
    • Lee SH, Shin H. Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering. Adv Drug Deliv Rev. 2007;59:339-59.
    • (2007) Adv Drug Deliv Rev. , vol.59 , pp. 339-359
    • Lee, S.H.1    Shin, H.2
  • 6
    • 4544273208 scopus 로고    scopus 로고
    • Bone tissue engineering: State of the art and future trends
    • 10.1002/mabi.200400026
    • Slgado AJ, Coutinho OP, Reis RL. Bone tissue engineering: state of the art and future trends. Macromol Bio Sci. 2004;4:743-65.
    • (2004) Macromol Bio Sci. , vol.4 , pp. 743-765
    • Slgado, A.J.1    Coutinho, O.P.2    Reis, R.L.3
  • 7
    • 84867404461 scopus 로고    scopus 로고
    • Tissue engineering
    • Shi D, editor Berlin: Springer
    • Liu Q. Tissue engineering. In: Shi D, editor. Biomaterials and tissue engineering. Berlin: Springer; 2004. p. 219-225.
    • (2004) Biomaterials and Tissue Engineering , pp. 219-225
    • Liu, Q.1
  • 8
    • 33748152402 scopus 로고    scopus 로고
    • Surface coatings for biological activation and functionalization of medical devices
    • 10.1016/j.surfcoat.2005.11.086 1:CAS:528:DC%2BD28XksVCnu7Y%3D
    • Hildebrand HF, Blanchemain N, Mayer G, Chai F, Lefebvre M, Boschin F. Surface coatings for biological activation and functionalization of medical devices. Surf Coat Technol. 2006;200:6318-24.
    • (2006) Surf Coat Technol. , vol.200 , pp. 6318-6324
    • Hildebrand, H.F.1    Blanchemain, N.2    Mayer, G.3    Chai, F.4    Lefebvre, M.5    Boschin, F.6
  • 9
    • 33746798218 scopus 로고    scopus 로고
    • Freeze casting of hydroxyapatite scaffolds for bone tissue engineering
    • 10.1016/j.biomaterials.2006.06.028 1:CAS:528:DC%2BD28XotVart7w%3D
    • Deville S, Saiz E, Tomsia AP. Freeze casting of hydroxyapatite scaffolds for bone tissue engineering. Biomaterials. 2006;27:5480-9.
    • (2006) Biomaterials. , vol.27 , pp. 5480-5489
    • Deville, S.1    Saiz, E.2    Tomsia, A.P.3
  • 11
    • 79958099714 scopus 로고    scopus 로고
    • In vivo performance of bilayer hydroxyapatite scaffolds for bone tissue regeneration in the rabbit radius
    • 10.1007/s10856-011-4241-7 1:CAS:528:DC%2BC3MXksVClurs%3D
    • Guda T, Walker JA, Pollot BE, Appleford MR, Ong JL, Wenke JC. In vivo performance of bilayer hydroxyapatite scaffolds for bone tissue regeneration in the rabbit radius. J Mater Sci Mater Med. 2011;22(3):647-56.
    • (2011) J Mater Sci Mater Med. , vol.22 , Issue.3 , pp. 647-656
    • Guda, T.1    Walker, J.A.2    Pollot, B.E.3    Appleford, M.R.4    Ong, J.L.5    Wenke, J.C.6
  • 12
    • 17844400927 scopus 로고    scopus 로고
    • Porosity of 3D biomaterial scaffolds and osteogenesis
    • 10.1016/j.biomaterials.2005.02.002 1:CAS:528:DC%2BD2MXjs1Wnsrc%3D
    • Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005;26:5474-91.
    • (2005) Biomaterials. , vol.26 , pp. 5474-5491
    • Karageorgiou, V.1    Kaplan, D.2
  • 13
    • 0036319948 scopus 로고    scopus 로고
    • Mechanical properties and in vitro cell compatibility of hydroxyapatite ceramics with graded pore structure
    • 10.1016/S0142-9612(02)00191-6 1:CAS:528:DC%2BD38XlvVelur8%3D
    • Werner J, Linner-Krcmar B, Friess W, Greil P. Mechanical properties and in vitro cell compatibility of hydroxyapatite ceramics with graded pore structure. Biomaterials. 2002;23:4285-94.
    • (2002) Biomaterials. , vol.23 , pp. 4285-4294
    • Werner, J.1    Linner-Krcmar, B.2    Friess, W.3    Greil, P.4
  • 14
    • 3042636110 scopus 로고    scopus 로고
    • Porosity variation in hydroxyapatite and osteoblast morphology: A scanning electron microscopy study
    • 10.1111/j.0022-2720.2004.01354.x 1:CAS:528:DC%2BD2cXmtFSlsbk%3D
    • Annaz B, Hing KA, Kayser M, Buckland T, Silvio LD. Porosity variation in hydroxyapatite and osteoblast morphology: a scanning electron microscopy study. J Microsc. 2004;215:100-10.
    • (2004) J Microsc. , vol.215 , pp. 100-110
    • Annaz, B.1    Hing, K.A.2    Kayser, M.3    Buckland, T.4    Silvio, L.D.5
  • 15
    • 66249145739 scopus 로고    scopus 로고
    • In vivo study on hydroxyapatite scaffolds with trabecular architecture for bone repair
    • 10.1002/jbm.a.32049 1:CAS:528:DC%2BD1MXls1ChtLk%3D
    • Appleford MR, Oh S, Oh N, Ong JL. In vivo study on hydroxyapatite scaffolds with trabecular architecture for bone repair. J Biomed Mater Res. 2009;89A:1019-27.
    • (2009) J Biomed Mater Res. , vol.89 , pp. 1019-1027
    • Appleford, M.R.1    Oh, S.2    Oh, N.3    Ong, J.L.4
  • 16
    • 0034116509 scopus 로고    scopus 로고
    • Osteoconduction at porous hydroxyapatite with various pore configurations
    • 10.1016/S0142-9612(00)00030-2 1:CAS:528:DC%2BD3cXjtF2jtLo%3D
    • Chang BS, Lee CK, Hong KS, Youn HJ, Ryu HS, Chung SS, et al. Osteoconduction at porous hydroxyapatite with various pore configurations. Biomaterials. 2000;21:1291-8.
    • (2000) Biomaterials. , vol.21 , pp. 1291-1298
    • Chang, B.S.1    Lee, C.K.2    Hong, K.S.3    Youn, H.J.4    Ryu, H.S.5    Chung, S.S.6
  • 17
    • 69049088738 scopus 로고    scopus 로고
    • Gene expression profile on chitosan/rhBMP2 films: A novel osteoinductive coating for implantation materials
    • 10.1016/j.actbio.2009.02.031 1:CAS:528:DC%2BD1MXht1Cqt7fF
    • Abarrategi A, Garcia-Cantalejo J, Moreno-Vocente C, Civantos A, Ramos V, Casado JVS, et al. Gene expression profile on chitosan/rhBMP2 films: a novel osteoinductive coating for implantation materials. Acta Biomater. 2009;5:2633-46.
    • (2009) Acta Biomater. , vol.5 , pp. 2633-2646
    • Abarrategi, A.1    Garcia-Cantalejo, J.2    Moreno-Vocente, C.3    Civantos, A.4    Ramos, V.5    Casado, J.V.S.6
  • 18
    • 70249124606 scopus 로고    scopus 로고
    • Controlled growth factor delivery for tissue engineering
    • 10.1002/adma.200900241
    • Tayalia P, Mooney DJ. Controlled growth factor delivery for tissue engineering. Adv Mater. 2009;21:1-17.
    • (2009) Adv Mater. , vol.21 , pp. 1-17
    • Tayalia, P.1    Mooney, D.J.2
  • 19
    • 84882860184 scopus 로고    scopus 로고
    • Tissue engineering of bone
    • C.V. Blitterswijk Thomsen D. Williams J. Hubbell R. Cancedda J.D. Bruijn (eds) et al. United Kingdom; Elsevier Inc Tissue Engineering
    • Gaalen SV, Kruyt M, Meijer G, Mistry A, Mikos A, Beucken JVD, et al. Tissue engineering of bone. In: Blitterswijk CV, Thomsen P, Williams D, Hubbell J, Cancedda R, Bruijn JD, et al., editors. editors. Tissue Engineering: United Kingdom; Elsevier Inc; 2008. p. 559-610.
    • (2008) Editors , pp. 559-610
    • Gaalen, S.V.1    Kruyt, M.2    Meijer, G.3    Mistry, A.4    Mikos, A.5    Beucken, J.V.D.6
  • 20
    • 0032007689 scopus 로고    scopus 로고
    • BMP-induced osteogenesis on the surface of hydroxyapatite with geometrically reasible and nonfeasible structures: Topology of osteogenesis
    • 10.1002/(SICI)1097-4636(199802)39:2<190: AID-JBM4>3.0.CO;2-K 1:CAS:528:DyaK1cXkvFWjtA%3D%3D
    • Kuboki Y, Takita H, Kobayashi D, Tsuruga E, Inoue M, Murata M, et al. BMP-induced osteogenesis on the surface of hydroxyapatite with geometrically reasible and nonfeasible structures: topology of osteogenesis. J Biomed Mater Res. 1998;39:190-9.
    • (1998) J Biomed Mater Res. , vol.39 , pp. 190-199
    • Kuboki, Y.1    Takita, H.2    Kobayashi, D.3    Tsuruga, E.4    Inoue, M.5    Murata, M.6
  • 21
    • 49349090133 scopus 로고    scopus 로고
    • Bone morphogenic proteins in tissue engineering: The road from laboratory to clinic, part II (BMP delivery)
    • 10.1002/term.74 1:CAS:528:DC%2BD1MXlvVajsb4%3D
    • Bessa PC, Casal M, Reis RL. Bone morphogenic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery). J Tissue Eng Reg Med. 2008;2:81-96.
    • (2008) J Tissue Eng Reg Med. , vol.2 , pp. 81-96
    • Bessa, P.C.1    Casal, M.2    Reis, R.L.3
  • 22
    • 21344473040 scopus 로고    scopus 로고
    • Delivery of bone morphogenic proteins for orthopedic tissue regeneration
    • 10.1016/j.cytogfr.2005.05.001 1:CAS:528:DC%2BD2MXlsl2rtb4%3D
    • Seeherman H, Wozney JM. Delivery of bone morphogenic proteins for orthopedic tissue regeneration. Cytokine Growth Factor Rev. 2005;16:329-45.
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 329-345
    • Seeherman, H.1    Wozney, J.M.2
  • 23
    • 70449706304 scopus 로고    scopus 로고
    • A bioactive coating of a silica xerogel/chitosan hybrid on titanium by a room temperature sol-gel process
    • 10.1016/j.actbio.2009.06.024 1:CAS:528:DC%2BC3cXotVWitg%3D%3D
    • Jun SH, Lee EJ, Yook SW, Kim HE, Kim HW, Koh YH. A bioactive coating of a silica xerogel/chitosan hybrid on titanium by a room temperature sol-gel process. Acta Biomater. 2010;6:302-7.
    • (2010) Acta Biomater. , vol.6 , pp. 302-307
    • Jun, S.H.1    Lee, E.J.2    Yook, S.W.3    Kim, H.E.4    Kim, H.W.5    Koh, Y.H.6
  • 24
    • 84355166617 scopus 로고    scopus 로고
    • Silica-chitosan hybrid coating on Ti for controlled release of growth factors
    • 10.1007/s10856-011-4458-5 1:CAS:528:DC%2BC3MXhsFegsbrM
    • Jun SH, Lee EJ, Kim HE, Jang JH, Koh YH. Silica-chitosan hybrid coating on Ti for controlled release of growth factors. J Mater Sci Mater Med. 2011;22:2757-64.
    • (2011) J Mater Sci Mater Med. , vol.22 , pp. 2757-2764
    • Jun, S.H.1    Lee, E.J.2    Kim, H.E.3    Jang, J.H.4    Koh, Y.H.5
  • 25
    • 57549086417 scopus 로고    scopus 로고
    • Membrane of hybrid chitosan-silica xerogel for guided bone regeneration
    • 10.1016/j.biomaterials.2008.10.025 1:CAS:528:DC%2BD1cXhsFWrtr7M
    • Lee EJ, Shin DS, Kim HE, Kim HW, Koh YH, Jang JH. Membrane of hybrid chitosan-silica xerogel for guided bone regeneration. Biomaterials. 2009;30:743-50.
    • (2009) Biomaterials. , vol.30 , pp. 743-750
    • Lee, E.J.1    Shin, D.S.2    Kim, H.E.3    Kim, H.W.4    Koh, Y.H.5    Jang, J.H.6
  • 26
    • 34249862774 scopus 로고    scopus 로고
    • Generation of large pore channels for bone tissue engineering using camphene-based freeze casting
    • 10.1111/j.1551-2916.2007.01670.x 1:CAS:528:DC%2BD2sXmvF2rsLw%3D
    • Yoon BH, Koh YH, Park CS, Kim HE. Generation of large pore channels for bone tissue engineering using camphene-based freeze casting. J Am Ceram Soc. 2007;90(6):1744-52.
    • (2007) J Am Ceram Soc. , vol.90 , Issue.6 , pp. 1744-1752
    • Yoon, B.H.1    Koh, Y.H.2    Park, C.S.3    Kim, H.E.4
  • 27
    • 34147186094 scopus 로고    scopus 로고
    • Highly porous hydroxyapatite bioceramics with interconnected pore channels using camphene-based freeze casting
    • 10.1016/j.matlet.2006.08.065 1:CAS:528:DC%2BD2sXktF2jsLo%3D
    • Lee EJ, Koh YH, Yoon BH, Kim HE, Kim HW. Highly porous hydroxyapatite bioceramics with interconnected pore channels using camphene-based freeze casting. Mater Lett. 2007;61:2270-3.
    • (2007) Mater Lett. , vol.61 , pp. 2270-2273
    • Lee, E.J.1    Koh, Y.H.2    Yoon, B.H.3    Kim, H.E.4    Kim, H.W.5
  • 28
    • 0142061588 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: How do they function and what can they offer the clinician?
    • 10.2334/josnusd.45.57
    • Sykarkas N, Opperman LA. Bone morphogenetic proteins: how do they function and what can they offer the clinician? J Oral Sci. 2003;45:57-73.
    • (2003) J Oral Sci. , vol.45 , pp. 57-73
    • Sykarkas, N.1    Opperman, L.A.2
  • 29
    • 0024514289 scopus 로고
    • Interporous hydroxyapatite as a bone-graft substitute in tibial plateau fractures
    • Bucholz RW, Carlton A, Holmes R. Interporous hydroxyapatite as a bone-graft substitute in tibial plateau fractures. Clin Orthop. 1989;240:53-62.
    • (1989) Clin Orthop. , vol.240 , pp. 53-62
    • Bucholz, R.W.1    Carlton, A.2    Holmes, R.3
  • 30
    • 0034765279 scopus 로고    scopus 로고
    • Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition
    • 10.1089/107632701753213183 1:STN:280:DC%2BD3MnmvVWjsw%3D%3D
    • Zeltinger J, Sherwood JK, Graham DA, Mueller R, Griffith LG. Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. Tissue Eng. 2001;7:557-72.
    • (2001) Tissue Eng. , vol.7 , pp. 557-572
    • Zeltinger, J.1    Sherwood, J.K.2    Graham, D.A.3    Mueller, R.4    Griffith, L.G.5
  • 31
    • 0030455198 scopus 로고    scopus 로고
    • BMP-2 can inhibit bone healing
    • 10.3109/17453679608997762
    • Jeppson C, Aspenberg P. BMP-2 can inhibit bone healing. Acta Orthop Scand. 1996;67:589-92.
    • (1996) Acta Orthop Scand. , vol.67 , pp. 589-592
    • Jeppson, C.1    Aspenberg, P.2
  • 32
    • 67650930432 scopus 로고    scopus 로고
    • BMP-2 release and dose-response studies in hydroxyapatite and b-tricalcium phosphate
    • 1:CAS:528:DC%2BD1MXotVelsbg%3D
    • Tazaki J, Murata M, Akazawa T, Yamamoto M, Ito K, Arisue M, Shibata T, et al. BMP-2 release and dose-response studies in hydroxyapatite and b-tricalcium phosphate. Bio-Med Mater Eng. 2009;19:141-6.
    • (2009) Bio-Med Mater Eng. , vol.19 , pp. 141-146
    • Tazaki, J.1    Murata, M.2    Akazawa, T.3    Yamamoto, M.4    Ito, K.5    Arisue, M.6    Shibata, T.7
  • 33
    • 73949143647 scopus 로고    scopus 로고
    • Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part B: Delivery systems for BMPs in orthopaedic and craniofacial tissue engineering
    • 10.1007/s10529-009-0100-8 1:CAS:528:DC%2BD1MXhtlKhtr3L
    • Haidar ZS, Hamdy RC, Tabrizian M. Delivery of recombinant bone morphogenetic proteins for bone regeneration and repair. Part B: delivery systems for BMPs in orthopaedic and craniofacial tissue engineering. Biotechnol Lett. 2009;31:1825-35.
    • (2009) Biotechnol Lett. , vol.31 , pp. 1825-1835
    • Haidar, Z.S.1    Hamdy, R.C.2    Tabrizian, M.3
  • 34
    • 0142061588 scopus 로고    scopus 로고
    • Bone morphogenetic proteins (BMPs): How do they function and what can they offer the clinician?
    • 10.2334/josnusd.45.57 1:CAS:528:DC%2BD3sXnslSjurs%3D
    • Sykaras N, Opperman LA. Bone morphogenetic proteins (BMPs): how do they function and what can they offer the clinician? J Oral Sci. 2003;45:57-73.
    • (2003) J Oral Sci. , vol.45 , pp. 57-73
    • Sykaras, N.1    Opperman, L.A.2
  • 35
    • 56349103304 scopus 로고    scopus 로고
    • The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats
    • 10.1002/jbm.a.31830 1:CAS:528:DC%2BD1cXhtlOqtbjE
    • Bodde EWH, Boerman OC, Russel FGM, Mikos AG, Spauwen PHM, Jansen JA. The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats. J Biomed Mater Res. 2008;87A:780-91.
    • (2008) J Biomed Mater Res. , vol.87 , pp. 780-791
    • Bodde, E.W.H.1    Boerman, O.C.2    Russel, F.G.M.3    Mikos, A.G.4    Spauwen, P.H.M.5    Jansen, J.A.6
  • 37
    • 0031838512 scopus 로고    scopus 로고
    • In vivo strength enhancement of hydroxyapatite combined with rhBMP-2
    • 10.1007/s007740050030 1:CAS:528:DyaK1cXltlCjsbY%3D
    • Ono I, Tateshita T, Inoue M, Kuboki Y. In vivo strength enhancement of hydroxyapatite combined with rhBMP-2. J Bone Miner Metal. 1998;16:81-7.
    • (1998) J Bone Miner Metal. , vol.16 , pp. 81-87
    • Ono, I.1    Tateshita, T.2    Inoue, M.3    Kuboki, Y.4
  • 38
    • 4644359945 scopus 로고    scopus 로고
    • Quinten Ruhe P, Spauwen PHM, Jansen JA. Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants inserted at an ectopic site in rabbits
    • 10.1016/j.biomaterials.2004.04.021 1:CAS:528:DC%2BD2cXnvVCjsr8%3D
    • Kroese-Deutman HC. Quinten Ruhe P, Spauwen PHM, Jansen JA. Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants inserted at an ectopic site in rabbits. Biomaterials. 2005;26:1131-8.
    • (2005) Biomaterials. , vol.26 , pp. 1131-1138
    • Kroese-Deutman, H.C.1
  • 39
    • 0242320973 scopus 로고    scopus 로고
    • In vitro effects of combined and sequential delivery of two bone growth factors
    • 10.1016/S0142-9612(03)00564-7 1:CAS:528:DC%2BD3sXosFOrtrY%3D
    • Raiche AT, Puleo DA. In vitro effects of combined and sequential delivery of two bone growth factors. Biomaterials. 2004;25:677-85.
    • (2004) Biomaterials. , vol.25 , pp. 677-685
    • Raiche, A.T.1    Puleo, D.A.2
  • 40
    • 34250019537 scopus 로고
    • Bone: Formation by autoinduction
    • 10.1126/science.150.3698.893 1:STN:280:DyaF28%2FhvFekuw%3D%3D
    • Urist MR. Bone: formation by autoinduction. Science. 1965;150:893-9.
    • (1965) Science. , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 41
    • 36849020930 scopus 로고    scopus 로고
    • Controlled drug delivery in tissue engineering
    • 10.1016/j.addr.2007.08.038 1:CAS:528:DC%2BD2sXhsVelt7vK
    • Biondi M, Ungaro F, Qualia F, Netti PA. Controlled drug delivery in tissue engineering. Adv Drug Deliv Rev. 2008;60:229-42.
    • (2008) Adv Drug Deliv Rev. , vol.60 , pp. 229-242
    • Biondi, M.1    Ungaro, F.2    Qualia, F.3    Netti, P.A.4
  • 42
    • 66249097765 scopus 로고    scopus 로고
    • Mineral apposition rates provide significant information on long-term effects in BMP-induced bone regeneration
    • 10.1002/jbm.a.32012 1:CAS:528:DC%2BD1MXltlelt7g%3D
    • Schopper C, Moser D, Spassova-Tzekova E, Russmueller G, Goriwoda W, Lagogiannis G, et al. Mineral apposition rates provide significant information on long-term effects in BMP-induced bone regeneration. J Biomed Mater Res. 2009;89A:679-86.
    • (2009) J Biomed Mater Res. , vol.89 , pp. 679-686
    • Schopper, C.1    Moser, D.2    Spassova-Tzekova, E.3    Russmueller, G.4    Goriwoda, W.5    Lagogiannis, G.6


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