-
1
-
-
84868282388
-
Insulin in central nervous system: More than just a peripheral hormone
-
Duarte AI, Moreira PI, Oliveira CR. Insulin in central nervous system: more than just a peripheral hormone. J Aging Res 2012; 2012: 384017.
-
(2012)
J Aging Res
, vol.2012
, pp. 384017
-
-
Duarte, A.I.1
Moreira, P.I.2
Oliveira, C.R.3
-
2
-
-
84874399491
-
Age-related gap in the management of heart failure patients. The National Project of Prevention and Treatment of Cardiovascular Diseases-POLKARD
-
Matusik P, Dubiel M, Wizner B, et al. Age-related gap in the management of heart failure patients. The National Project of Prevention and Treatment of Cardiovascular Diseases-POLKARD. Cardiol J 2012; 19(2): 146-52.
-
(2012)
Cardiol J
, vol.19
, Issue.2
, pp. 146-152
-
-
Matusik, P.1
Dubiel, M.2
Wizner, B.3
-
3
-
-
84860704002
-
Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases
-
Hegde ML, Mantha AK, Hazra TK, et al. Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. Mech Ageing Dev 2012; 133(4): 157-68.
-
(2012)
Mech Ageing Dev
, vol.133
, Issue.4
, pp. 157-168
-
-
Hegde, M.L.1
Mantha, A.K.2
Hazra, T.K.3
-
4
-
-
84863803158
-
The implications of anatomical and functional changes of the aging kidney: With an emphasis on the glomeruli
-
Glassock RJ, Rule AD. The implications of anatomical and functional changes of the aging kidney: with an emphasis on the glomeruli. Kidney Int 2012; 82(3): 270-7.
-
(2012)
Kidney Int
, vol.82
, Issue.3
, pp. 270-277
-
-
Glassock, R.J.1
Rule, A.D.2
-
5
-
-
0022414054
-
Diagnosis of Alzheimer's disease
-
Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol 1985; 42(11): 1097-105.
-
(1985)
Arch Neurol
, vol.42
, Issue.11
, pp. 1097-1105
-
-
Khachaturian, Z.S.1
-
6
-
-
34249697099
-
Forecasting the global burden of Alzheimer's disease
-
Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. Forecasting the global burden of Alzheimer's disease. Alzheimers Dement 2007; 3(3): 186-91.
-
(2007)
Alzheimers Dement
, vol.3
, Issue.3
, pp. 186-191
-
-
Brookmeyer, R.1
Johnson, E.2
Ziegler-Graham, K.3
Arrighi, H.M.4
-
7
-
-
77949336151
-
Alzheimer's disease facts and figures
-
Alzheimer A. 2010 Alzheimer's disease facts and figures. Alzheimers Dement 2010; 6(2): 158-94.
-
(2010)
Alzheimers Dement
, vol.6
, Issue.2
, pp. 158-194
-
-
Alzheimer, A.1
-
8
-
-
84864285795
-
Management of hyperglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012; 55(6): 1577-96.
-
(2012)
Diabetologia
, vol.55
, Issue.6
, pp. 1577-1596
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
9
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A, Stolk RP, van Harskamp F, Pols HA, Hofman A, Breteler MM. Diabetes mellitus and the risk of dementia: The Rotterdam Study. Neurology 1999; 53(9): 1937-42.
-
(1999)
Neurology
, vol.53
, Issue.9
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
10
-
-
2442424380
-
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
-
Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004; 61(5): 661-6.
-
(2004)
Arch Neurol
, vol.61
, Issue.5
, pp. 661-666
-
-
Arvanitakis, Z.1
Wilson, R.S.2
Bienias, J.L.3
Evans, D.A.4
Bennett, D.A.5
-
11
-
-
0036759508
-
Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest old
-
Hassing LB, Johansson B, Nilsson SE, et al. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr 2002; 14(3): 239-48.
-
(2002)
Int Psychogeriatr
, vol.14
, Issue.3
, pp. 239-248
-
-
Hassing, L.B.1
Johansson, B.2
Nilsson, S.E.3
-
12
-
-
5344237420
-
Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
-
Xu WL, Qiu CX, Wahlin A, Winblad B, Fratiglioni L. Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology 2004; 63(7): 1181-6.
-
(2004)
Neurology
, vol.63
, Issue.7
, pp. 1181-1186
-
-
Xu, W.L.1
Qiu, C.X.2
Wahlin, A.3
Winblad, B.4
Fratiglioni, L.5
-
13
-
-
74049099554
-
The relationship between Alzheimer's disease and diabetes: Type 3 diabetes?
-
Kroner Z. The relationship between Alzheimer's disease and diabetes: Type 3 diabetes? Altern Med Rev 2009; 14(4): 373-9.
-
(2009)
Altern Med Rev
, vol.14
, Issue.4
, pp. 373-379
-
-
Kroner, Z.1
-
14
-
-
77957898888
-
How does diabetes accelerate Alzheimer disease pathology?
-
Sims-Robinson C, Kim B, Rosko A, Feldman EL. How does diabetes accelerate Alzheimer disease pathology? Nat Rev Neurol 2010; 6(10): 551-9.
-
(2010)
Nat Rev Neurol
, vol.6
, Issue.10
, pp. 551-559
-
-
Sims-Robinson, C.1
Kim, B.2
Rosko, A.3
Feldman, E.L.4
-
15
-
-
79956158458
-
Molecular mechanisms linking diabetes mellitus and Alzheimer disease: Beta-amyloid peptide, insulin signaling, and neuronal function
-
Takeda S, Sato N, Rakugi H, Morishita R. Molecular mechanisms linking diabetes mellitus and Alzheimer disease: beta-amyloid peptide, insulin signaling, and neuronal function. Mol Biosyst 2011; 7(6): 1822-7.
-
(2011)
Mol Biosyst
, vol.7
, Issue.6
, pp. 1822-1827
-
-
Takeda, S.1
Sato, N.2
Rakugi, H.3
Morishita, R.4
-
16
-
-
84867537762
-
Amyloid-beta and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model
-
Bitel CL, Kasinathan C, Kaswala RH, Klein WL, Frederikse PH. Amyloid-beta and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model. J Alzheimers Dis 2012; 32(2): 291-305.
-
(2012)
J Alzheimers Dis
, vol.32
, Issue.2
, pp. 291-305
-
-
Bitel, C.L.1
Kasinathan, C.2
Kaswala, R.H.3
Klein, W.L.4
Frederikse, P.H.5
-
17
-
-
84860599622
-
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities
-
Carvalho C, Cardoso S, Correia SC, et al. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes 2012; 61(5): 1234-42.
-
(2012)
Diabetes
, vol.61
, Issue.5
, pp. 1234-1242
-
-
Carvalho, C.1
Cardoso, S.2
Correia, S.C.3
-
18
-
-
23044442730
-
The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease
-
Nicolls MR. The clinical and biological relationship between Type II diabetes mellitus and Alzheimer's disease. Curr Alzheimer Res 2004; 1(1): 47-54.
-
(2004)
Curr Alzheimer Res
, vol.1
, Issue.1
, pp. 47-54
-
-
Nicolls, M.R.1
-
19
-
-
53549097355
-
Insulin resistance and Alzheimer's disease: Molecular links & clinical implications
-
Neumann KF, Rojo L, Navarrete LP, et al. Insulin resistance and Alzheimer's disease: molecular links & clinical implications. Curr Alzheimer Res 2008; 5(5): 438-47.
-
(2008)
Curr Alzheimer Res
, vol.5
, Issue.5
, pp. 438-447
-
-
Neumann, K.F.1
Rojo, L.2
Navarrete, L.P.3
-
20
-
-
84857714157
-
Mechanisms underlying insulin deficiency-induced acceleration of betaamyloidosis in a mouse model of Alzheimer's disease
-
Devi L, Alldred MJ, Ginsberg SD, Ohno M. Mechanisms underlying insulin deficiency-induced acceleration of betaamyloidosis in a mouse model of Alzheimer's disease. PLoS One 2012; 7(3): e32792.
-
(2012)
PLoS One
, vol.7
, Issue.3
-
-
Devi, L.1
Alldred, M.J.2
Ginsberg, S.D.3
Ohno, M.4
-
21
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
-
Watson GS, Craft S. The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment. CNS Drugs 2003; 17(1): 27-45.
-
(2003)
CNS Drugs
, vol.17
, Issue.1
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
22
-
-
0037238285
-
Insulin and the blood-brain barrier
-
Woods SC, Seeley RJ, Baskin DG, Schwartz MW. Insulin and the blood-brain barrier. Curr Pharm Des 2003; 9(10): 795-800.
-
(2003)
Curr Pharm Des
, vol.9
, Issue.10
, pp. 795-800
-
-
Woods, S.C.1
Seeley, R.J.2
Baskin, D.G.3
Schwartz, M.W.4
-
23
-
-
0018090354
-
Insulin receptors are widely distributed in the central nervous system of the rat
-
Havrankova J, Roth J, Brownstein M. Insulin receptors are widely distributed in the central nervous system of the rat. Nature 1978; 272(5656): 827-9.
-
(1978)
Nature
, vol.272
, Issue.5656
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
Brownstein, M.3
-
24
-
-
34548241662
-
Molecular connexions between dementia and diabetes
-
Cole AR, Astell A, Green C, Sutherland C. Molecular connexions between dementia and diabetes. Neurosci Biobehav Rev 2007; 31(7): 1046-63.
-
(2007)
Neurosci Biobehav Rev
, vol.31
, Issue.7
, pp. 1046-1063
-
-
Cole, A.R.1
Astell, A.2
Green, C.3
Sutherland, C.4
-
25
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
Saltiel AR. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 2001; 104(4): 517-29.
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 517-529
-
-
Saltiel, A.R.1
-
26
-
-
14044273751
-
Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor
-
Miyamoto Y, Chen L, Sato M, et al. Hippocampal synaptic modulation by the phosphotyrosine adapter protein ShcC/N-Shc via interaction with the NMDA receptor. J Neurosci 2005; 25(7): 1826-35.
-
(2005)
J Neurosci
, vol.25
, Issue.7
, pp. 1826-1835
-
-
Miyamoto, Y.1
Chen, L.2
Sato, M.3
-
27
-
-
33745215607
-
Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat
-
Horwood JM, Dufour F, Laroche S, Davis S. Signalling mechanisms mediated by the phosphoinositide 3-kinase/Akt cascade in synaptic plasticity and memory in the rat. Eur J Neurosci 2006; 23(12): 3375-84.
-
(2006)
Eur J Neurosci
, vol.23
, Issue.12
, pp. 3375-3384
-
-
Horwood, J.M.1
Dufour, F.2
Laroche, S.3
Davis, S.4
-
28
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel CJ, Wilson CA, Lee VM, Klein PS. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 2003; 423(6938): 435-9.
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
29
-
-
70349505965
-
Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes
-
Beeler N, Riederer BM, Waeber G, Abderrahmani A. Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes. Brain Res Bull 2009; 80(4-5): 274-81.
-
(2009)
Brain Res Bull
, vol.80
, Issue.4-5
, pp. 274-281
-
-
Beeler, N.1
Riederer, B.M.2
Waeber, G.3
Abderrahmani, A.4
-
30
-
-
34249776342
-
c-Jun phosphorylation in Alzheimer disease
-
Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res 2007; 85(8): 1668-73.
-
(2007)
J Neurosci Res
, vol.85
, Issue.8
, pp. 1668-1673
-
-
Thakur, A.1
Wang, X.2
Siedlak, S.L.3
Perry, G.4
Smith, M.A.5
Zhu, X.6
-
31
-
-
77951028451
-
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes
-
Takeda S, Sato N, Uchio-Yamada K, et al. Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci USA 2010; 107(15): 7036-41.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.15
, pp. 7036-7041
-
-
Takeda, S.1
Sato, N.2
Uchio-Yamada, K.3
-
32
-
-
70949084806
-
Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease
-
Ke YD, Delerue F, Gladbach A, Gotz J, Ittner LM. Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS One 2009; 4(11): e7917.
-
(2009)
PLoS One
, vol.4
, Issue.11
-
-
Ke, Y.D.1
Delerue, F.2
Gladbach, A.3
Gotz, J.4
Ittner, L.M.5
-
33
-
-
84860778998
-
Staging and natural history of cerebrovascular pathology in dementia
-
Deramecourt V, Slade JY, Oakley AE, et al. Staging and natural history of cerebrovascular pathology in dementia. Neurology 2012; 78(14): 1043-50.
-
(2012)
Neurology
, vol.78
, Issue.14
, pp. 1043-1050
-
-
Deramecourt, V.1
Slade, J.Y.2
Oakley, A.E.3
-
34
-
-
80051508807
-
Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline
-
Debette S, Seshadri S, Beiser A, et al. Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology 2011; 77(5): 461-8.
-
(2011)
Neurology
, vol.77
, Issue.5
, pp. 461-468
-
-
Debette, S.1
Seshadri, S.2
Beiser, A.3
-
35
-
-
84859316471
-
Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits
-
Tong XK, Lecrux C, Rosa-Neto P, Hamel E. Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits. J Neurosci 2012; 32(14): 4705-15.
-
(2012)
J Neurosci
, vol.32
, Issue.14
, pp. 4705-4715
-
-
Tong, X.K.1
Lecrux, C.2
Rosa-Neto, P.3
Hamel, E.4
-
36
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988; 240(4852): 622-30.
-
(1988)
Science
, vol.240
, Issue.4852
, pp. 622-630
-
-
Mahley, R.W.1
-
37
-
-
0023926909
-
Apolipoprotein (apo) A-I production and mRNA abundance explain plasma apoA-I and high density lipoprotein differences between two nonhuman primate species with high and low susceptibilities to diet-induced hypercholesterolemia
-
Sorci-Thomas M, Prack MM, Dashti N, et al. Apolipoprotein (apo) A-I production and mRNA abundance explain plasma apoA-I and high density lipoprotein differences between two nonhuman primate species with high and low susceptibilities to diet-induced hypercholesterolemia. J Biol Chem 1988; 263(11): 5183-9.
-
(1988)
J Biol Chem
, vol.263
, Issue.11
, pp. 5183-5189
-
-
Sorci-Thomas, M.1
Prack, M.M.2
Dashti, N.3
-
38
-
-
0033787023
-
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene
-
Nickerson DA, Taylor SL, Fullerton SM, et al. Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. Genome Res 2000; 10(10): 1532-45.
-
(2000)
Genome Res
, vol.10
, Issue.10
, pp. 1532-1545
-
-
Nickerson, D.A.1
Taylor, S.L.2
Fullerton, S.M.3
-
39
-
-
33646425609
-
Putting cholesterol in its place: ApoE and reverse cholesterol transport
-
Mahley RW, Huang Y, Weisgraber KH. Putting cholesterol in its place: apoE and reverse cholesterol transport. J Clin Invest 2006; 116(5): 1226-9.
-
(2006)
J Clin Invest
, vol.116
, Issue.5
, pp. 1226-1229
-
-
Mahley, R.W.1
Huang, Y.2
Weisgraber, K.H.3
-
40
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet 2007; 39(1): 17-23.
-
(2007)
Nat Genet
, vol.39
, Issue.1
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
-
41
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
Lambert JC, Heath S, Even G, et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 2009; 41(10): 1094-9.
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
-
42
-
-
77649314191
-
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
-
Morris JC, Roe CM, Xiong C, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol 2010; 67(1): 122-31.
-
(2010)
Ann Neurol
, vol.67
, Issue.1
, pp. 122-131
-
-
Morris, J.C.1
Roe, C.M.2
Xiong, C.3
-
43
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance
-
Castellano JM, Kim J, Stewart FR, et al. Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance. Sci Transl Med 2011; 3(89): 89ra57.
-
(2011)
Sci Transl Med
, vol.3
, Issue.89
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
-
44
-
-
0037087052
-
Apolipoprotein E polymorphism and cardiovascular disease: A HuGE review
-
Eichner JE, Dunn ST, Perveen G, et al. Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am J Epidemiol 2002; 155(6): 487-95.
-
(2002)
Am J Epidemiol
, vol.155
, Issue.6
, pp. 487-495
-
-
Eichner, J.E.1
Dunn, S.T.2
Perveen, G.3
-
45
-
-
84872476007
-
Diabetic atherosclerosis in APOE*4 mice: Synergy between lipoprotein metabolism and vascularinflammation
-
Johnson LA, Kim HS, Knudson MJ, et al. Diabetic atherosclerosis in APOE*4 mice: Synergy between lipoprotein metabolism and vascularinflammation. J Lipid Res 2012; 54(2): 386-96.
-
(2012)
J Lipid Res
, vol.54
, Issue.2
, pp. 386-396
-
-
Johnson, L.A.1
Kim, H.S.2
Knudson, M.J.3
-
46
-
-
35748972367
-
Food-derived advanced glycation end products (AGEs): A novel therapeutic target for various disorders
-
Yamagishi S, Ueda S, Okuda S. Food-derived advanced glycation end products (AGEs): a novel therapeutic target for various disorders. Curr Pharm: Des 2007; 13(27): 2832-6.
-
(2007)
Curr Pharm: Des
, vol.13
, Issue.27
, pp. 2832-2836
-
-
Yamagishi, S.1
Ueda, S.2
Okuda, S.3
-
47
-
-
1942438654
-
Advanced glycation end-products and the progress of diabetic vascular complications
-
Jakus V, Rietbrock N. Advanced glycation end-products and the progress of diabetic vascular complications. Physiol Res 2004; 53(2): 131-42.
-
(2004)
Physiol Res
, vol.53
, Issue.2
, pp. 131-142
-
-
Jakus, V.1
Rietbrock, N.2
-
48
-
-
0034992635
-
Increased protein glycation in cerebrospinal fluid of Alzheimer's disease
-
Shuvaev VV, Laffont I, Serot JM, et al. Increased protein glycation in cerebrospinal fluid of Alzheimer's disease. Neurobiol Aging 2001; 22(3): 397-402.
-
(2001)
Neurobiol Aging
, vol.22
, Issue.3
, pp. 397-402
-
-
Shuvaev, V.V.1
Laffont, I.2
Serot, J.M.3
-
49
-
-
77953621114
-
The Maillard reaction in the human body. The main discoveries and factors that affect glycation
-
Tessier FJ. The Maillard reaction in the human body. The main discoveries and factors that affect glycation. Pathol Biol (Paris) 2010; 58(3): 214-9.
-
(2010)
Pathol Biol (Paris)
, vol.58
, Issue.3
, pp. 214-219
-
-
Tessier, F.J.1
-
50
-
-
70449732132
-
Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus
-
Valente T, Gella A, Fernandez-Busquets X, Unzeta M, Durany N. Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus. Neurobiol Dis 2010; 37(1): 67-76.
-
(2010)
Neurobiol Dis
, vol.37
, Issue.1
, pp. 67-76
-
-
Valente, T.1
Gella, A.2
Fernandez-Busquets, X.3
Unzeta, M.4
Durany, N.5
-
51
-
-
78649516312
-
Oxidative stress in Alzheimer's disease hippocampus: A topographical study
-
Cruz-Sanchez FF, Girones X, Ortega A, Alameda F, Lafuente JV. Oxidative stress in Alzheimer's disease hippocampus: a topographical study. J Neurol Sci 2010; 299(1/2): 163-7.
-
(2010)
J Neurol Sci
, vol.299
, Issue.1-2
, pp. 163-167
-
-
Cruz-Sanchez, F.F.1
Girones, X.2
Ortega, A.3
Alameda, F.4
Lafuente, J.V.5
-
52
-
-
78650659385
-
Apical-to-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein
-
Candela P, Gosselet F, Saint-Pol J, et al. Apical-to-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein. J Alzheimers Dis 2010; 22(3): 849-59.
-
(2010)
J Alzheimers Dis
, vol.22
, Issue.3
, pp. 849-859
-
-
Candela, P.1
Gosselet, F.2
Saint-Pol, J.3
-
53
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 2001; 60(8): 759-67.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
-
54
-
-
71749121998
-
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
-
Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta 2010; 1802(1): 2-10.
-
(2010)
Biochim Biophys Acta
, vol.1802
, Issue.1
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.3
Smith, M.A.4
Perry, G.5
-
55
-
-
0030689041
-
Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells
-
Tiedge M, Lortz S, Drinkgern J, Lenzen S. Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes 1997; 46(11): 1733-42.
-
(1997)
Diabetes
, vol.46
, Issue.11
, pp. 1733-1742
-
-
Tiedge, M.1
Lortz, S.2
Drinkgern, J.3
Lenzen, S.4
-
56
-
-
43649097838
-
Oxidative injury and neuropathy in diabetes and impaired glucose tolerance
-
Russell JW, Berent-Spillson A, Vincent AM, et al. Oxidative injury and neuropathy in diabetes and impaired glucose tolerance. Neurobiol Dis 2008; 30(3): 420-9.
-
(2008)
Neurobiol Dis
, vol.30
, Issue.3
, pp. 420-429
-
-
Russell, J.W.1
Berent-Spillson, A.2
Vincent, A.M.3
-
57
-
-
84870671396
-
Involvement of Oxidative Stress in Suppression of Insulin Biosynthesis under Diabetic Conditions
-
Kaneto H, Matsuoka TA. Involvement of Oxidative Stress in Suppression of Insulin Biosynthesis under Diabetic Conditions. Int J Mol Sci 2012; 13(10): 13680-90.
-
(2012)
Int J Mol Sci
, vol.13
, Issue.10
, pp. 13680-13690
-
-
Kaneto, H.1
Matsuoka, T.A.2
-
58
-
-
84862854070
-
Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose
-
Sun LQ, Zhao J, Zhang TT, et al. Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose. Neurochem Res 2012; 37(5): 996-1010.
-
(2012)
Neurochem Res
, vol.37
, Issue.5
, pp. 996-1010
-
-
Sun, L.Q.1
Zhao, J.2
Zhang, T.T.3
-
59
-
-
84863688106
-
Mitochondrialand endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: From pathogenesis to biomarkers
-
Ferreiro E, Baldeiras I, Ferreira IL, et al. Mitochondrialand endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers. Int J Cell Biol 2012; 2012: 735206.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 735206
-
-
Ferreiro, E.1
Baldeiras, I.2
Ferreira, I.L.3
-
60
-
-
0029073455
-
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
-
Lovell MA, Ehmann WD, Butler SM, Markesbery WR. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 1995; 45(8): 1594-601.
-
(1995)
Neurology
, vol.45
, Issue.8
, pp. 1594-1601
-
-
Lovell, M.A.1
Ehmann, W.D.2
Butler, S.M.3
Markesbery, W.R.4
-
61
-
-
0032031780
-
Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease
-
Marcus DL, Thomas C, Rodriguez C, et al. Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol 1998; 150(1): 40-4.
-
(1998)
Exp Neurol
, vol.150
, Issue.1
, pp. 40-44
-
-
Marcus, D.L.1
Thomas, C.2
Rodriguez, C.3
-
62
-
-
16844382331
-
Evidence of increased oxidative damage in subjects with mild cognitive impairment
-
Keller JN, Schmitt FA, Scheff SW, et al. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 2005; 64(7): 1152-6.
-
(2005)
Neurology
, vol.64
, Issue.7
, pp. 1152-1156
-
-
Keller, J.N.1
Schmitt, F.A.2
Scheff, S.W.3
-
63
-
-
84855394403
-
Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease
-
Buizza L, Cenini G, Lanni C, et al. Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease. PLoS One 2012; 7(1): e29789.
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Buizza, L.1
Cenini, G.2
Lanni, C.3
-
64
-
-
79251623365
-
Diabetes mellitus and Alzheimer's disease: Shared pathology and treatment?
-
Akter K, Lanza EA, Martin SA, et al. Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br J Clin Pharmacol 2011; 71(3): 365-76.
-
(2011)
Br J Clin Pharmacol
, vol.71
, Issue.3
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
-
65
-
-
84861078831
-
A review: Inflammatory process in Alzheimer's disease, role of cytokines
-
Rubio-Perez JM, Morillas-Ruiz JM. A review: inflammatory process in Alzheimer's disease, role of cytokines. Sci World J 2012; 2012: 756357.
-
(2012)
Sci World J
, vol.2012
, pp. 756357
-
-
Rubio-Perez, J.M.1
Morillas-Ruiz, J.M.2
-
66
-
-
84865005208
-
Alzheimer disease: Prostaglandin E(2) signalling is implicated in inflammation early in the Alzheimer disease course
-
Wood H. Alzheimer disease: Prostaglandin E(2) signalling is implicated in inflammation early in the Alzheimer disease course. Nat Rev Neurol 2012; 8(8): 411.
-
(2012)
Nat Rev Neurol
, vol.8
, Issue.8
, pp. 411
-
-
Wood, H.1
-
67
-
-
84871955193
-
Inflammatory prostaglandin E(2) signaling in a mouse model of Alzheimer disease
-
Shi J, Wang Q, Johansson JU, et al. Inflammatory prostaglandin E(2) signaling in a mouse model of Alzheimer disease. Ann Neurol 2012; 72(5): 788-98.
-
(2012)
Ann Neurol
, vol.72
, Issue.5
, pp. 788-798
-
-
Shi, J.1
Wang, Q.2
Johansson, J.U.3
-
68
-
-
84863207973
-
PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice
-
Vennemann A, Gerstner A, Kern N, et al. PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice. Diabetes 2012; 61(7): 1879-87.
-
(2012)
Diabetes
, vol.61
, Issue.7
, pp. 1879-1887
-
-
Vennemann, A.1
Gerstner, A.2
Kern, N.3
-
69
-
-
77950352189
-
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
-
Li Y, Duffy KB, Ottinger MA, et al. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. J Alzheimers Dis 2010; 19(4): 1205-19.
-
(2010)
J Alzheimers Dis
, vol.19
, Issue.4
, pp. 1205-1219
-
-
Li, Y.1
Duffy, K.B.2
Ottinger, M.A.3
-
70
-
-
79955749452
-
The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
-
McClean PL, Parthsarathy V, Faivre E, Holscher C. The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. J Neurosci 2011; 31(17): 6587-94.
-
(2011)
J Neurosci
, vol.31
, Issue.17
, pp. 6587-6594
-
-
McClean, P.L.1
Parthsarathy, V.2
Faivre, E.3
Holscher, C.4
-
71
-
-
0034651101
-
Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
-
Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE. Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J Neurosci 2000; 20(2): 558-67.
-
(2000)
J Neurosci
, vol.20
, Issue.2
, pp. 558-567
-
-
Combs, C.K.1
Johnson, D.E.2
Karlo, J.C.3
Cannady, S.B.4
Landreth, G.E.5
-
72
-
-
84860795758
-
Amorfrutins are potent antidiabetic dietary natural products
-
Weidner C, de Groot JC, Prasad A, et al. Amorfrutins are potent antidiabetic dietary natural products. Proc Natl Acad Sci USA 2012; 109(19): 7257-62.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.19
, pp. 7257-7262
-
-
Weidner, C.1
de Groot, J.C.2
Prasad, A.3
-
73
-
-
79551474326
-
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk
-
Reitz C, Tokuhiro S, Clark LN, et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol 2011; 69(1): 47-64.
-
(2011)
Ann Neurol
, vol.69
, Issue.1
, pp. 47-64
-
-
Reitz, C.1
Tokuhiro, S.2
Clark, L.N.3
-
74
-
-
84875153955
-
An intronic ncRNA-dependent regulation of SORL1 expression affecting Abeta formation is upregulated in post-mortem Alzheimer's disease brain samples
-
Ciarlo E, Massone S, Penna I, et al. An intronic ncRNA-dependent regulation of SORL1 expression affecting Abeta formation is upregulated in post-mortem Alzheimer's disease brain samples. Dis Model Mech: 2012; 6(2): 424-33.
-
(2012)
Dis Model Mech
, vol.6
, Issue.2
, pp. 424-433
-
-
Ciarlo, E.1
Massone, S.2
Penna, I.3
-
75
-
-
84862831893
-
SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population
-
Wang HF, Yu JT, Zhang W, et al. SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population. Brain Res 2012; 1448: 111-6.
-
(2012)
Brain Res
, vol.1448
, pp. 111-116
-
-
Wang, H.F.1
Yu, J.T.2
Zhang, W.3
-
76
-
-
77449128370
-
Complications Trial/Epidemiology of Diabetes I, Complications Research G. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose
-
Paterson AD, Waggott D, Boright AP, et al. Complications Trial/Epidemiology of Diabetes I, Complications Research G. A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Diabetes 2010; 59(2): 539-49.
-
(2010)
Diabetes
, vol.59
, Issue.2
, pp. 539-549
-
-
Paterson, A.D.1
Waggott, D.2
Boright, A.P.3
-
77
-
-
84867270258
-
Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes
-
Lane RF, St George-Hyslop P, Hempstead BL, et al. Vps10 family proteins and the retromer complex in aging-related neurodegeneration and diabetes. J Neurosci 2012; 32(41): 14080-6.
-
(2012)
J Neurosci
, vol.32
, Issue.41
, pp. 14080-14086
-
-
Lane, R.F.1
George-Hyslop, P.2
Hempstead, B.L.3
-
78
-
-
34347389636
-
SORCS1: A novel human type 2 diabetes susceptibility gene suggested by the mouse
-
Goodarzi MO, Lehman DM, Taylor KD, et al. SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes 2007; 56(7): 1922-9.
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1922-1929
-
-
Goodarzi, M.O.1
Lehman, D.M.2
Taylor, K.D.3
-
79
-
-
61649092571
-
Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10
-
Liang X, Slifer M, Martin ER, et al. Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10. Hum Mutat 2009; 30(3): 463-71.
-
(2009)
Hum Mutat
, vol.30
, Issue.3
, pp. 463-471
-
-
Liang, X.1
Slifer, M.2
Martin, E.R.3
-
80
-
-
84855525518
-
Genetics of late-onset Alzheimer's disease: Update from the alzgene database and analysis of shared pathways
-
Olgiati P, Politis AM, Papadimitriou GN, De Ronchi D, Serretti A. Genetics of late-onset Alzheimer's disease: update from the alzgene database and analysis of shared pathways. Int J Alzheimers Dis 2011; 2011: 832379.
-
Int J Alzheimers Dis
, vol.2011
, Issue.83
, pp. 2011
-
-
Olgiati, P.1
Politis, A.M.2
Papadimitriou, G.N.3
de Ronchi, D.4
Serretti, A.5
-
81
-
-
84870895663
-
Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions
-
Son SM, Song H, Byun J, et al. Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions. Autophagy 2012; 8(12): 1842-4.
-
(2012)
Autophagy
, vol.8
, Issue.12
, pp. 1842-1844
-
-
Son, S.M.1
Song, H.2
Byun, J.3
-
82
-
-
35448954937
-
Elevated butyrylcholinesterase and acetylcholinesterase may predict the development of type 2 diabetes mellitus and Alzheimer's disease
-
Rao AA, Sridhar GR, Das UN. Elevated butyrylcholinesterase and acetylcholinesterase may predict the development of type 2 diabetes mellitus and Alzheimer's disease. Med Hypotheses 2007; 69(6): 1272-6.
-
(2007)
Med Hypotheses
, vol.69
, Issue.6
, pp. 1272-1276
-
-
Rao, A.A.1
Sridhar, G.R.2
Das, U.N.3
-
83
-
-
79955727727
-
The cholinergic system in aging and neuronal degeneration
-
Schliebs R, Arendt T. The cholinergic system in aging and neuronal degeneration. Behav Brain Res 2011; 221(2): 555-63.
-
(2011)
Behav Brain Res
, vol.221
, Issue.2
, pp. 555-563
-
-
Schliebs, R.1
Arendt, T.2
-
84
-
-
0034001450
-
Autonomic regulation of islet hormone secretion-- implications for health and disease
-
Ahren B. Autonomic regulation of islet hormone secretion-- implications for health and disease. Diabetologia 2000; 43(4): 393-410.
-
(2000)
Diabetologia
, vol.43
, Issue.4
, pp. 393-410
-
-
Ahren, B.1
-
85
-
-
77953844541
-
Cholinergic augmentation of insulin release requires ankyrin-B
-
Healy JA, Nilsson KR, Hohmeier HE, et al. Cholinergic augmentation of insulin release requires ankyrin-B. Sci Signal 2010; 3(113): ra19.
-
(2010)
Sci Signal
, vol.3
, Issue.113
-
-
Healy, J.A.1
Nilsson, K.R.2
Hohmeier, H.E.3
-
86
-
-
80054096801
-
Cholinesterases, a target of pharmacology and toxicology
-
Pohanka M. Cholinesterases, a target of pharmacology and toxicology. Biomed Pap Med FacUniv Palacky Olomouc Czech Repub 2011; 155(3): 219-29.
-
(2011)
Biomed Pap Med FacUniv Palacky Olomouc Czech Repub
, vol.155
, Issue.3
, pp. 219-229
-
-
Pohanka, M.1
-
87
-
-
20244371673
-
Rate of progression of cognitive decline in Alzheimer's disease: Effect of butyrylcholinesterase K gene variation
-
Holmes C, Ballard C, Lehmann D, et al. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation. J Neurol Neurosurg Psychiatry 2005; 76(5): 640-3.
-
(2005)
J Neurol Neurosurg Psychiatry
, vol.76
, Issue.5
, pp. 640-643
-
-
Holmes, C.1
Ballard, C.2
Lehmann, D.3
-
88
-
-
70450280811
-
Targeting BuChE-inflammatory pathway by SK0506 to manage type 2 diabetes and Alzheimer disease
-
Kamal MA, Tan Y, Seale JP, Qu X. Targeting BuChE-inflammatory pathway by SK0506 to manage type 2 diabetes and Alzheimer disease. Neurochem Res 2009; 34(12): 2163-9.
-
(2009)
Neurochem Res
, vol.34
, Issue.12
, pp. 2163-2169
-
-
Kamal, M.A.1
Tan, Y.2
Seale, J.P.3
Qu, X.4
-
89
-
-
79951795388
-
Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome
-
Tan Y, Kamal MA, Wang ZZ, et al. Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome. Clin Sci (Lond) 2011; 120(7): 297-305.
-
(2011)
Clin Sci (Lond)
, vol.120
, Issue.7
, pp. 297-305
-
-
Tan, Y.1
Kamal, M.A.2
Wang, Z.Z.3
-
90
-
-
78651521685
-
The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies
-
Lu SH, Wu JW, Liu HL, et al. The discovery of potential acetylcholinesterase inhibitors: a combination of pharmacophore modeling, virtual screening, and molecular docking studies. J Biomed Sci 2011; 18: 8.
-
(2011)
J Biomed Sci
, vol.18
, pp. 8
-
-
Lu, S.H.1
Wu, J.W.2
Liu, H.L.3
-
91
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000; 1(2): 120-9.
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, Issue.2
, pp. 120-129
-
-
Mattson, M.P.1
-
92
-
-
33747040344
-
U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases
-
Koh CH, Qi RZ, Qu D, et al. U18666A-mediated apoptosis in cultured murine cortical neurons: role of caspases, calpains and kinases. Cell Signal 2006; 18(10): 1572-1583.
-
(2006)
Cell Signal
, vol.18
, Issue.10
, pp. 1572-1583
-
-
Koh, C.H.1
Qi, R.Z.2
Qu, D.3
-
93
-
-
33847660492
-
Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: Microarray and proteomics analyses in cultured murine cortical neurons
-
Koh CH, Peng ZF, Ou K, et al. Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: microarray and proteomics analyses in cultured murine cortical neurons. J Cell Physiol 2007; 211(1): 63-87.
-
(2007)
J Cell Physiol
, vol.211
, Issue.1
, pp. 63-87
-
-
Koh, C.H.1
Peng, Z.F.2
Ou, K.3
-
94
-
-
0036452144
-
Cholesterol in Alzheimer's disease and tauopathy
-
Burns M, Duff K. Cholesterol in Alzheimer's disease and tauopathy. Ann NY Acad Sci 2002; 977: 367-375.
-
(2002)
Ann NY Acad Sci
, vol.977
, pp. 367-375
-
-
Burns, M.1
Duff, K.2
-
95
-
-
0142045683
-
Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease
-
Ohm TG, Treiber-Held S, Distl R, et al. Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease. Pharmacopsychiatry 2003; 36(Suppl 2): S120-S126.
-
(2003)
Pharmacopsychiatry
, vol.36
, Issue.SUPPL. 2
-
-
Ohm, T.G.1
Treiber-Held, S.2
Distl, R.3
-
96
-
-
70349125386
-
Neurite outgrowth induced by spicatoside A, a steroidal saponin, via the tyrosine kinase A receptor pathway
-
Hur J, Lee P, Moon E, et al. Neurite outgrowth induced by spicatoside A, a steroidal saponin, via the tyrosine kinase A receptor pathway. Eur J Pharmacol 2009; 620(1-3): 9-15.
-
(2009)
Eur J Pharmacol
, vol.620
, Issue.1-3
, pp. 9-15
-
-
Hur, J.1
Lee, P.2
Moon, E.3
|