Targeting BuChE-inflammatory pathway by SK0506 to manage type 2 diabetes and Alzheimer disease

Neurochemical Research

Volumn 34, Issue 12, 2009, Pages 2163-2169

  Kamal, M A ^a   Tan, Y ^a   Seale, J P ^b   Qu, X ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b University of Sydney   (Australia)

Author keywords

Alzheimer's disease; Butyrylcholineesterase; Chinese herbal medicines; IL 6; TNF ; Type 2 diabetes

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLINESTERASE; GLUCOSE; HERBACEOUS AGENT; INTERLEUKIN 6; ROSIGLITAZONE; SK 0506; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; INFLAMMATION; LOW DRUG DOSE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ADIPOSE TISSUE; ALANINE TRANSAMINASE; ALZHEIMER DISEASE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BUTYRYLCHOLINESTERASE; DIABETES MELLITUS, TYPE 2; DIETARY FATS; DRUGS, CHINESE HERBAL; FATTY LIVER; INFLAMMATION; INTERLEUKIN-6; RATS; THIAZOLIDINEDIONES; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 70450280811     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-0011-z     Document Type: Article

References (27)

1. CL Leibson 1997 Risk of dementia among persons with diabetes mellitus: a population-based cohort study Am J Epidemiol 145 301 308 1:STN:280: DyaK2s7ovVKkuw%3D%3D 9054233
2. JL Cummings 2004 Alzheimer's disease N Engl J Med 351 56 67 10.1056/NEJMra040223 10.1056/NEJMra040223 1:CAS:528:DC%2BD2cXltlOjsb8%3D 15229308 (Pubitemid 38857248)
3. MR Farlow JL Cummings 2007 Effective pharmacologic management of Alzheimer's disease Am J Med 120 388 397 10.1016/j.amjmed.2006.08.036 10.1016/j.amjmed.2006.08.036 1:CAS:528:DC%2BD2sXkslWku7s%3D 17466645 (Pubitemid 46627453)
4. AA Rao GR Sridhar UN Das 2007 Elevated butyrylcholinesterase and acetylcholinesterase may predict the development of type 2 diabetes mellitus and Alzheimer's disease Med Hypotheses 69 1272 1276 10.1016/j.mehy.2007.03.032 1:CAS:528:DC%2BD2sXht1ahsb%2FM 17553629 (Pubitemid 47633064)
5. GR Sridhar H Thota AR Allam CS Babu AS Prasad Ch Divakar 2006 Alzheimer's disease and type 2 diabetes mellitus: the cholinesterase connection? Lipids Health Dis 5 28 10.1186/1476-511X-5-28 17096857 (Pubitemid 44818485)
6. S Darvesh DA Hopkins C Geula 2003 Neurobiology of butyrylcholinesterase Nat Rev Neurosci 4 131 138 10.1038/nrn1035 10.1038/nrn1035 1:CAS:528: DC%2BD3sXot12hsg%3D%3D 12563284 (Pubitemid 37271383)
7. LV Borovikova S Ivanova M Zhang H Yang GI Botchkina LR Watkins, et al. 2000 Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin Nature 405 458 462 10.1038/35013070 10.1038/35013070 1:CAS:528:DC%2BD3cXjslyltbY%3D 10839541 (Pubitemid 30367422)
8. L Zhou Z Zuo MS Chow 2005 Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use J Clin Pharmacol 45 1345 1359 10.1177/0091270005282630 10.1177/0091270005282630 1:CAS:528:DC%2BD2MXhtlSjtrzL 16291709 (Pubitemid 41643896)
9. XY Yu SG Lin X Chen ZW Zhou J Liang W Duan B Chowbay JY Wen E Chan J Cao CG Li SF Zhou 2007 Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier Curr Drug Metab 8 365 378 10.2174/138920007780655441 10.2174/138920007780655441 1:CAS:528: DC%2BD2sXmsFehu7s%3D 17504224 (Pubitemid 46780064)
10. Y Tan PJ Seale Z-Z Wang X Qu 2007 Effects of Chinese herbal extracts on metabolic syndrome in highest fat fed rats Diabetes 56 A690 10.2337/db06-0921 (Pubitemid 46348472)
11. GL Ellman KD Courtney Jr V Andres RM Featherstone 1961 A new and rapid colorimetric determination of acetylcholinesterase activity Biochem Pharmacol 7 88 95 10.1016/0006-2952(61)90145-9 10.1016/0006-2952(61)90145-9 1:CAS:528:DyaF3MXht1Gns7o%3D 13726518
12. MA Kamal AA Al-Jafari Q-S Yu NH Greig 2006 Kinetic analysis of the inhibition of human butyrylcholinesterase with cymserine Biochim Biophys Acta 1760 200 206 1:CAS:528:DC%2BD28XitVarsL0%3D 16309845
13. MA Kamal Q-S Yu HW Holloway D Tweedie P Klein NH Greig 2006 Kinetics of human serum butyrylcholinesterase and its inhibition by a novel experimental Alzheimer therapeutic, bisnorcymserine J Alzheimers Dis 10 43 51 1:CAS:528:DC%2BD28XpsValt7s%3D 16988481
14. MA Kamal P Klein Q-S Yu HW Holloway D Tweedie NH Greig 2008 Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine Neurochem Res 33 5 745 753 10.1007/s11064-007-9490-y 10.1007/s11064-007-9490-y 1:CAS:528: DC%2BD1cXjsFGitrs%3D 17985237
15. MA Kamal X Qu Q-s Yu D Tweedie HW Holloway Y Li Y Tan NH Greig 2008 Tetrahydrofurobenzofuran cymserine, a potent butyrylcholinesterase inhibitor and experimental Alzheimer drug candidate, enzyme kinetic analysis J Neural Transm 115 6 889 898 10.1007/s00702-008-0022-y 10.1007/s00702-008-0022-y 1:CAS:528:DC%2BD1cXmslWrs7s%3D 18235987
16. V Bradamante Z Krnić R Zrinski P Konjevoda Z Reiner 2006 Changes in butyrylcholinesterase activity and serum lipids after oxprenolol and glibenclamide treatments in non-diabetic rats Arzneimittelforschung 56 2 64 69 1:CAS:528:DC%2BD28Xjs1Onu74%3D 16572919
17. Silver A (1974) The biology of cholinesterases. Elsevier, Amsterdam
18. Soreq H, Zakut H (1993) Human cholinesterases and anticholinesterases. Academic Press, New York
19. S Darvesh DA Hopkins 2003 Differential distribution of butyrylcholinesterase and acetylcholinesterase in the human thalamus J Comp Neurol 463 25 43 10.1002/cne.10751 10.1002/cne.10751 1:CAS:528: DC%2BD3sXmsFCgt7Y%3D 12811800 (Pubitemid 36835411)
20. Giacobini E (2003) Butyrlcholinesterase: Its function and inhibitors. Martin Dunitz, London and New York
21. S Darvesh DL Grantham DA Hopkins 1998 Butyrylcholinesterase in normal human amygdala and hippocampal formation J Comp Neurol 393 374 390 10.1002/(SICI)1096-9861(19980413)393:3<374::AID-CNE8>3.0.CO;2-Z 10.1002/(SICI)1096-9861(19980413)393:3<374::AID-CNE8>3.0.CO;2-Z 1:CAS:528:DyaK1cXit1WksLo%3D 9548556 (Pubitemid 28164592)
22. MA Kamal NH Greig M Reale 2009 Anti-Inflammatory properties of acetylcholinesterase inhibitors administered in Alzheimer's disease Anti-Inflamm Anti-Allergy Agents Med Chem 8 1 85 100 10.2174/187152309787580810 10.2174/187152309787580810 1:CAS:528:DC%2BD1MXks1Sqt7c%3D
23. S Craft 2006 Insulin resistance syndrome and Alzheimer disease: pathophysiologic mechanisms and therapeutic implications Alzheimer Dis Assoc Disord 20 4 298 301 10.1097/01.wad.0000213866.86934.7e 10.1097/01.wad. 0000213866.86934.7e 1:CAS:528:DC%2BD28Xht1Cnt77P 17132977 (Pubitemid 44900946)
24. KF Neumann L Rojo LP Navarrete G Farías P Reyes RB Maccioni 2008 Insulin resistance and Alzheimer's disease: molecular links & clinical implications Curr Alzh Res 5 5 438 447 10.2174/156720508785908919 10.2174/156720508785908919 1:CAS:528:DC%2BD1cXhtFCqsLnK
25. GL Peng XY Zhang 2007 Effects of Salvia miltiorrhiza on serum levels of inflammatory cytokines in patients with severe acute pancreatitis Zhong Xi Yi Jie He Xue Bao 5 1 28 31 10.3736/jcim20070106 10.3736/jcim20070106 1:CAS:528:DC%2BD2sXitFShsL8%3D 17214932
26. Jin YC, Kim CW, Kim YM, Nizamutdinova IT, Ha YM, Kim HJ, Seo HG, Son KH, Jeon SJ, Kang SS, Kim YS, Kam SC, Lee JH, Chang KC (2009) Cryptotanshinone, a lipophilic compound of Salvia miltiorrriza root, inhibits TNF-alpha-induced expression of adhesion molecules in HUVEC and attenuates rat myocardial ischemia/reperfusion injury in vivo. Eur J Pharmacol (in press)
27. WS Jung YS Chae DY Kim SW Seo HJ Park GS Bae TH Kim HJ Oh KJ Yun RK Park JS Kim EC Kim SY Hwang SJ Park HJ Song 2008 Gardenia jasminoides protects against cerulein-induced acute pancreatitis World J Gastroenterol 14 40 6188 6194 10.3748/wjg.14.6188 10.3748/wjg.14.6188 18985809