Unraveling mechanisms underlying partial agonism in 5-HT3A receptors

Journal of Neuroscience

Volumn 34, Issue 50, 2014, Pages 16865-16876

  Corradi, Jeremías ^a   Bouzat, Cecilia ^a  

^a Universidad Nacional del Sur Consejo Nacional de Investigaciones Científicas y Técnicas ^*  (Argentina)

Author keywords

5 HT3; Kinetics; Ligand gated ion channel; Patch clamp; Serotonin; Single channel

Indexed keywords

SEROTONIN 3A RECEPTOR; PROTEIN BINDING; SEROTONIN 3 AGONIST; SEROTONIN 3 RECEPTOR;

ARTICLE; CELL MEMBRANE CONDUCTANCE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MOLECULAR DOCKING; PARTIAL AGONISM; PATCH CLAMP TECHNIQUE; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIMULATION; ANIMAL; CHEMISTRY; FEMALE; HEK293 CELL LINE; MALE; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; TRANSGENIC MOUSE;

ANIMALS; DRUG PARTIAL AGONISM; FEMALE; HEK293 CELLS; HUMANS; MALE; MICE; MICE, TRANSGENIC; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN 5-HT3 RECEPTOR AGONISTS;

EID: 84916631932     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1970-14.2014     Document Type: Article

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