Selection of distinct conformational states of the 5-HT3 receptor by full and partial agonists

British Journal of Pharmacology

Volumn 117, Issue 5, 1996, Pages 839-846

  Van Hooft, Johannes A ^a   Vijverberg, Henk P M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

5 HT3 receptor; Agonist efficacy; Conformational selection; Desensitization; Ligand gated ion channel; N1E 115 neuroblastoma cells; Single channel patch clamp; Whole cell voltage clamp

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; DOPAMINE; ION CHANNEL; PARTIAL AGONIST; SEROTONIN; SEROTONIN 3 RECEPTOR; SEROTONIN AGONIST; TRYPTAMINE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DESENSITIZATION; DRUG POTENCY; ION CONDUCTANCE; ION CURRENT; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP;

EID: 0029963024     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15269.x     Document Type: Article

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