Open probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancy

Journal of Physiology

Volumn 535, Issue 2, 2001, Pages 427-443

  Mott, David D ^a   Erreger, Kevin ^a   Banke, Tue G ^a   Traynelis, Stephen F ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN 3 RECEPTOR; SEROTONIN 3A RECEPTOR; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DESENSITIZATION; ELECTRIC POTENTIAL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; RAT; TIME; VOLTAGE CLAMP;

ANIMALS; CELL LINE; GENE EXPRESSION; HUMANS; ION CHANNEL GATING; KIDNEY; KINETICS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; RODENTIA; SEROTONIN; XENOPUS LAEVIS;

EID: 0035449927     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.00427.x     Document Type: Article

References (88)

1. Controlling emesis related to cancer therapy
2. Drug blockade of open end-plate channels
3. Interaction of tretraethylammonium ion derivatives with the potassium channels of giant axons
4. Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase
5. 3 receptors in outside-out patches of N1E-115 neuroblastoma cells: Basic properties and effects of pentobarbital
6. 3 receptor in CNS disorders
7. 3 receptor antagonism in the control of cytostatic drug-induced emesis
8. Ultrastructure of the 5-hydroxytryptamine3 receptor
9. Molecular biology of 5-HT receptors
10. 3 receptor in the human forebrain
11. Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor
12. Activation of ion channels in the frog end-plate by high concentrations of acetylcholine
13. 3 agonists and antagonists
14. Pathophysiology and pharmacology of migraine. Is there a place for antiemetics in future treatment strategies?
15. 3B subunit is a major determinant of serotonin-receptor function
16. 3 receptors are membrane ion channels
17. 3B receptor subunit
18. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities
19. ATP mediates fast synaptic transmission in mammalian neurons
20. 3 receptor desensitization by fluoxetine
21. Irritable bowel syndrome: New pharmaceutical approaches to treatment
22. 3 receptor stably expressed in HEK 293 cells
23. 3 receptor splice variants isolated from a mouse hippocampal cell line
24. 3 receptors provides new insights into their maturation and structure
25. 3 receptor antagonists. Clinical pharmacology and therapeutic applications
26. Investigation of the alpha(1)-glycine receptor channel-opening kinetics in the submillisecond time domain
27. 3 receptors
28. Serotonin receptor physiology: Relation to emesis
29. Dendritic and somatic glutamate receptor channels in rat cerebellar Purkinje cells
30. Kinetics of homomeric GluR6 glutamate receptor channels
31. Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: Comparison with native mouse receptors
32. 3 receptor channel
33. 3A, in the rat: An in situ hybridization study
34. 3-receptor antagonist
35. A receptor
36. A channel responses to brief agonist pulses
37. 3 receptor channel desensitization in rat glioma x mouse neuroblastoma hybrid NG108-15 cells
38. 3 receptors in the rat hippocampal dentate gyrus: A patch clamp study
39. 3 receptor subunit
40. A reluctant gating mode of glycine receptor channels determines the time course of inhibitory miniature synaptic events in zebrafish hindbrain neurons
41. About the antiemetic effectivity of granisetron in chemotherapy-induced acute emesis: A comparison of results with intravenous and oral dosing
42. NMDA channel behavior depends on agonist affinity
43. Opening rate of acetylcholine receptor channels
44. Decamethonium is a partial agonist at the acetylcholine nicotinic receptor
45. A single amino-acid in the tm1 domain is an important determinant of the desensitization kinetics of recombinant human and guinea pig alpha-homomeric 5-hydroxytryptamine type 3 receptors
46. The channel opening rate of adult- and fetal-type mouse muscle nicotinic receptors activated by acetylcholine
47. A receptors open?
48. 3 receptor, a serotonin-gated ion channel
49. Known calcium channel α1 subunits can form low threshold small conductance channels with similarities to native T-type channels
50. A molecular determinant for submillisecond desensitization in glutamate receptors
51. 3 receptors
52. Immunological characterization and transmembrane topology of 5-hydroxy-tryptamine3 receptors by functional epitope tagging
53. Local anaesthetics transiently block currents through single acetylcholine receptor channels
54. Evolutionary history of the ligand-gated ion-channel superfamily of receptors
55. α7 receptor-selective agonists and modes of α7 receptor activation
56. 3 antiemetic therapy for patients with breast cancer
57. 3 receptor-induced currents in N1E-115 neuroblastoma cells
58. The kinetics of the response to glutamate and kainate in neurons of the avian cochlear nucleus
59. 3 receptors
60. 3 receptor-gated currents in adult rat dorsal root ganglion neurones
61. 3 receptors in developing visual cortex
62. Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro
63. The tetrameric structure of a glutamate receptor channel
64. 3 receptor label both native and recombinant receptors
65. 3 receptors in rat amygdala
66. Role of serotonin drugs in the treatment of social phobia
67. 2+-permeable P2X receptor chanels in cultured rat retinal ganglion cells
68. 3 receptor mRNA
69. Expression of a serotonin-gated ion channel in embryonic neural and nonneural tissues
70. Software based correction of single compartment series resistance errors
71. Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit
72. 3 receptor activation and desensitization
73. 3 channels
74. 3 receptor channels
75. Control of rat GluR6 glutamate receptor open probability by protein kinase A and calcineurin
76. 3 receptors
77. 2+-permeable ion channels
78. 3 receptor by full and partial agonists
79. Ondansetron - A new safe and effective antiemetic in patients receiving high dose melphalan
80. 3 receptor gene and functional expression of two splice variants
81. An efficient and portable pseudo random number generator
82. Single-channel activations and concentration jumps: Comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors
83. Single amino acid substitution affects desensitization of the 5-hydroxytryptamine type 3 receptor expressed in Xenopus oocytes
84. 3 receptor in a rat glioma x mouse neuroblastoma hybrid cell
85. Ion permeation through 5-hydroxytryptamine-gated channels in neuroblastoma N18 cells
86. 3 receptor channels in dissociated rat superior cervical ganglion neurons