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Volumn 18, Issue 1, 2015, Pages 63-70

Beta-alanine supplementation, muscle carnosine and exercise performance

Author keywords

Dietary supplement; High intensity exercise performance; L carnosine; PH buffering

Indexed keywords

BETA ALANINE; BICARBONATE; BUFFER; CALCIUM; CARNOSINE; ANTIOXIDANT;

EID: 84916631712     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000127     Document Type: Review
Times cited : (81)

References (47)
  • 1
    • 33646548555 scopus 로고    scopus 로고
    • The absorption of orally supplied betaalanine and its effect on muscle carnosine synthesis in human vastus lateralis
    • Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied betaalanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006; 30: 279-289.
    • (2006) Amino Acids , vol.30 , pp. 279-289
    • Harris, R.C.1    Tallon, M.J.2    Dunnett, M.3
  • 2
    • 33846696040 scopus 로고    scopus 로고
    • Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity
    • Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007; 32: 225-233.
    • (2007) Amino Acids , vol.32 , pp. 225-233
    • Hill, C.A.1    Harris, R.C.2    Kim, H.J.3
  • 3
    • 84862770558 scopus 로고    scopus 로고
    • Effect of two b-alanine dosing protocols on muscle carnosine synthesis and washout
    • Stellingwerff T, Anwander H, Egger A, et al. Effect of two b-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012; 42: 2461-2472.
    • (2012) Amino Acids , vol.42 , pp. 2461-2472
    • Stellingwerff, T.1    Anwander, H.2    Egger, A.3
  • 4
    • 84862756837 scopus 로고    scopus 로고
    • Effect of slow-release b-alanine tablets on absorption kinetics and paresthesia
    • Décombaz J, Beaumont M, Vuichoud J, et al. Effect of slow-release b-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012; 43: 67-76.
    • (2012) Amino Acids , vol.43 , pp. 67-76
    • Décombaz, J.1    Beaumont, M.2    Vuichoud, J.3
  • 5
    • 84880572257 scopus 로고    scopus 로고
    • Meal and beta-alanine coingestion enhances muscle carnosine loading
    • Stegen S, Blancquaert L, Everaert I, et al. Meal and beta-alanine coingestion enhances muscle carnosine loading. Med Sci Sports Exerc 2013; 45: 1478-1485.
    • (2013) Med Sci Sports Exerc , vol.45 , pp. 1478-1485
    • Stegen, S.1    Blancquaert, L.2    Everaert, I.3
  • 6
    • 84892947495 scopus 로고    scopus 로고
    • Muscle carnosine loading by beta-alanine supplementation is more pronounced in trained vs. Untrained muscles
    • Bex T, Chung W, Baguet A, et al. Muscle carnosine loading by beta-alanine supplementation is more pronounced in trained vs. untrained muscles. J Appl Physiol 2014; 116: 204-209.
    • (2014) J Appl Physiol , vol.116 , pp. 204-209
    • Bex, T.1    Chung, W.2    Baguet, A.3
  • 7
    • 67349092823 scopus 로고    scopus 로고
    • The effect of 4 weeks beta-alanine supplementation and isokinetic training on carnosine concentrations in type I and II human skeletal muscle fibres
    • Kendrick IP, Kim HJ, Harris RC, et al. The effect of 4 weeks beta-alanine supplementation and isokinetic training on carnosine concentrations in type I and II human skeletal muscle fibres. Eur J Appl Physiol 2009; 106: 131-138.
    • (2009) Eur J Appl Physiol , vol.106 , pp. 131-138
    • Kendrick, I.P.1    Kim, H.J.2    Harris, R.C.3
  • 8
    • 64349116247 scopus 로고    scopus 로고
    • Carnosine loading and washout in human skeletal muscles
    • Baguet A, Reyngoudt H, Pottier A, et al. Carnosine loading and washout in human skeletal muscles. J Appl Physiol 2009; 106: 837-842.
    • (2009) J Appl Physiol , vol.106 , pp. 837-842
    • Baguet, A.1    Reyngoudt, H.2    Pottier, A.3
  • 9
    • 84902549257 scopus 로고    scopus 로고
    • The beta-alanine dose for maintaining moderately elevated muscle carnosine levels
    • Stegen S, Bex T, Vervaet C, et al. The beta-alanine dose for maintaining moderately elevated muscle carnosine levels. Med Sci Sports Exerc 2014; 46: 1426-1432.
    • (2014) Med Sci Sports Exerc , vol.46 , pp. 1426-1432
    • Stegen, S.1    Bex, T.2    Vervaet, C.3
  • 10
    • 84876305879 scopus 로고    scopus 로고
    • Gene expression of carnosinerelated enzymes and transporters in skeletal muscle
    • Everaert I, De Naeyer H, Taes Y, Derave W. Gene expression of carnosinerelated enzymes and transporters in skeletal muscle. Eur J Appl Physiol 2013; 113: 1169-1179.
    • (2013) Eur J Appl Physiol , vol.113 , pp. 1169-1179
    • Everaert, I.1    De Naeyer, H.2    Taes, Y.3    Derave, W.4
  • 11
    • 77951248998 scopus 로고    scopus 로고
    • Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1)
    • Drozak J, Veiga-da-Cunha M, Vertommen D, et al. Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1). J Biol Chem 2010; 285: 9346-9356.
    • (2010) J Biol Chem , vol.285 , pp. 9346-9356
    • Drozak, J.1    Veiga-da-Cunha, M.2    Vertommen, D.3
  • 12
    • 84877979027 scopus 로고    scopus 로고
    • Molecular identification of carnosine N-methyltransferase as chicken Histamine N-methyltransferase-like Protein (HNMT-Like)
    • Drozak J, Chrobok L, Poleszak O, et al. Molecular identification of carnosine N-methyltransferase as chicken Histamine N-methyltransferase-like Protein (HNMT-Like). PLoS One 2013; 8: E64805.
    • (2013) PLoS One , vol.8 , pp. e64805
    • Drozak, J.1    Chrobok, L.2    Poleszak, O.3
  • 13
    • 84904194388 scopus 로고    scopus 로고
    • Metabolite proofreading in carnosine and homocarnosine syn thesis: Molecular identification of PM20D2 as b-alanyl-lysine dipeptidase
    • Veiga-da-Cunha M, Chevalier N, Stroobant V, et al. Metabolite proofreading in carnosine and homocarnosine synthesis: Molecular identification of PM20D2 as b-alanyl-lysine dipeptidase. J Biol Chem 2014; 289: 19726-19736.
    • (2014) J Biol Chem , vol.289 , pp. 19726-19736
    • Veiga-da-Cunha, M.1    Chevalier, N.2    Stroobant, V.3
  • 14
    • 84884784140 scopus 로고    scopus 로고
    • Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates
    • Baba SP, Hoetker JD, Merchant M, et al. Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates. J Biol Chem 2013; 288: 28163-28179.
    • (2013) J Biol Chem , vol.288 , pp. 28163-28179
    • Baba, S.P.1    Hoetker, J.D.2    Merchant, M.3
  • 15
    • 84862741562 scopus 로고    scopus 로고
    • Effects of b-alanine supplementation on exercise performance: A meta-analysis
    • Hobson RM, Saunders B, Ball G, et al. Effects of b-alanine supplementation on exercise performance: A meta-analysis. Amino Acids 2012; 43: 25-37.
    • (2012) Amino Acids , vol.43 , pp. 25-37
    • Hobson, R.M.1    Saunders, B.2    Ball, G.3
  • 16
    • 78149309497 scopus 로고    scopus 로고
    • Important role of muscle carnosine in rowing performance
    • Baguet A, Bourgois J, Vanhee L, et al. Important role of muscle carnosine in rowing performance. J Appl Physiol 2010; 109: 1096-1101.
    • (2010) J Appl Physiol , vol.109 , pp. 1096-1101
    • Baguet, A.1    Bourgois, J.2    Vanhee, L.3
  • 18
    • 84878238316 scopus 로고    scopus 로고
    • Effect of beta-alanine supplementation on 2000-m rowing-ergometer performance
    • Ducker KJ, Dawson B, Wallman KE. Effect of beta-alanine supplementation on 2000-m rowing-ergometer performance. Int J Sport Nutr Exerc Metab 2013; 23: 336-343.
    • (2013) Int J Sport Nutr Exerc Metab , vol.23 , pp. 336-343
    • Ducker, K.J.1    Dawson, B.2    Wallman, K.E.3
  • 19
    • 84888291597 scopus 로고    scopus 로고
    • Effect of beta-alanine with and without sodium bicarbonate on 2, 000-m rowing performance
    • Hobson RM, Harris RC, Martin D, et al. Effect of beta-alanine with and without sodium bicarbonate on 2, 000-m rowing performance. Int J Sport Nutr Exerc Metab 2013; 23: 480-487.
    • (2013) Int J Sport Nutr Exerc Metab , vol.23 , pp. 480-487
    • Hobson, R.M.1    Harris, R.C.2    Martin, D.3
  • 20
    • 84903774374 scopus 로고    scopus 로고
    • Doubling of muscle carnosine concentration does not improve laboratory 1-h cycling time trial performance
    • Chung W, Baguet A, Bex T, et al. Doubling of muscle carnosine concentration does not improve laboratory 1-h cycling time trial performance. Int J Sport Nutr Exerc Metab 2014; 24: 315-324.
    • (2014) Int J Sport Nutr Exerc Metab , vol.24 , pp. 315-324
    • Chung, W.1    Baguet, A.2    Bex, T.3
  • 21
    • 84868146701 scopus 로고    scopus 로고
    • Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers
    • Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012; 4: 1441-1453.
    • (2012) Nutrients , vol.4 , pp. 1441-1453
    • Chung, W.1    Shaw, G.2    Anderson, M.E.3
  • 22
    • 84877733383 scopus 로고    scopus 로고
    • The ergogenic effect of betaalanine combined with sodium bicarbonate on high-intensity swimming performance
    • De Salles Painelli V, Roschel H, de Jesus F, et al. The ergogenic effect of betaalanine combined with sodium bicarbonate on high-intensity swimming performance. Appl Physiol Nutr Metab 2013; 38: 525-532.
    • (2013) Appl Physiol Nutr Metab , vol.38 , pp. 525-532
    • De Salles Painelli, V.1    Roschel, H.2    De Jesus, F.3
  • 23
    • 84887137460 scopus 로고    scopus 로고
    • Effect of sodium bicarbonate and betaalanine supplementation on maximal sprint swimming
    • Mero AA, Hirvonen P, Saarela J, et al. Effect of sodium bicarbonate and betaalanine supplementation on maximal sprint swimming. J Int Soc Sports Nutr 2013; 10: 52.
    • (2013) J Int Soc Sports Nutr , vol.10 , pp. 52
    • Mero, A.A.1    Hirvonen, P.2    Saarela, J.3
  • 24
    • 84862772561 scopus 로고    scopus 로고
    • Effect of beta-alanine supplementation on repeated sprint performance during the loughborough intermittent shuttle test
    • Saunders B, Sale C, Harris RC, Sunderland C. Effect of beta-alanine supplementation on repeated sprint performance during the Loughborough Intermittent Shuttle Test. Amino Acids 2012; 43: 39-47.
    • (2012) Amino Acids , vol.43 , pp. 39-47
    • Saunders, B.1    Sale, C.2    Harris, R.C.3    Sunderland, C.4
  • 25
    • 84888295379 scopus 로고    scopus 로고
    • Effect of beta alanine and sodium bicarbonate supplementation on repeated-sprint performance
    • Ducker KJ, Dawson B, Wallman KE. Effect of beta alanine and sodium bicarbonate supplementation on repeated-sprint performance. J Strength Cond Res 2013; 27: 3450-3460.
    • (2013) J Strength Cond Res , vol.27 , pp. 3450-3460
    • Ducker, K.J.1    Dawson, B.2    Wallman, K.E.3
  • 26
    • 84870467214 scopus 로고    scopus 로고
    • High-velocity intermittent running: Effects of beta-alanine supplementation
    • Smith-Ryan AE, Fukuda DH, Stout JR, Kendall KL. High-velocity intermittent running: Effects of beta-alanine supplementation. J Strength Cond Res 2012; 26: 2798-2805.
    • (2012) J Strength Cond Res , vol.26 , pp. 2798-2805
    • Smith-Ryan, A.E.1    Fukuda, D.H.2    Stout, J.R.3    Kendall, K.L.4
  • 27
    • 35649013167 scopus 로고    scopus 로고
    • Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters
    • Derave W, Ozdemir MS, Harris RC, et al. Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. J Appl Physiol 2007; 103: 1736-1743.
    • (2007) J Appl Physiol , vol.103 , pp. 1736-1743
    • Derave, W.1    Ozdemir, M.S.2    Harris, R.C.3
  • 28
    • 84904980715 scopus 로고    scopus 로고
    • Dietary nitrate supplementation and exercise performance
    • Jones AM. Dietary nitrate supplementation and exercise performance. Sports Med 2014; 44: 35-45.
    • (2014) Sports Med , vol.44 , pp. 35-45
    • Jones, A.M.1
  • 29
    • 84906726231 scopus 로고    scopus 로고
    • Nitrate supplementation and highintensity performance in competitive cyclists
    • Hoon MW, Hopkins WG, Jones AM, et al. Nitrate supplementation and highintensity performance in competitive cyclists. Appl Physiol Nutr Metab 2014; 39: 1043-1049.
    • (2014) Appl Physiol Nutr Metab , vol.39 , pp. 1043-1049
    • Hoon, M.W.1    Hopkins, W.G.2    Jones, A.M.3
  • 30
    • 84898839150 scopus 로고    scopus 로고
    • Influence of training status on high-intensity intermittent performance in response to b-alanine supplementation
    • De Salles Painelli V, Saunders B, Sale C, et al. Influence of training status on high-intensity intermittent performance in response to b-alanine supplementation. Amino Acids 2014; 46: 1207-1215.
    • (2014) Amino Acids , vol.46 , pp. 1207-1215
    • De Salles Painelli, V.1    Saunders, B.2    Sale, C.3
  • 31
    • 80052965149 scopus 로고    scopus 로고
    • Effect of b-alanine plus sodium bicarbonate on high-intensity cycling capacity
    • Sale C, Saunders B, Hudson S, et al. Effect of b-alanine plus sodium bicarbonate on high-intensity cycling capacity. Med Sci Sports Exerc 2011; 43: 1972-1978.
    • (2011) Med Sci Sports Exerc , vol.43 , pp. 1972-1978
    • Sale, C.1    Saunders, B.2    Hudson, S.3
  • 32
    • 84863989507 scopus 로고    scopus 로고
    • Effect of combined b-alanine and sodium bicarbonate supplementation on cycling performance
    • Bellinger PM, Howe ST, Shing CM, Fell JW. Effect of combined b-alanine and sodium bicarbonate supplementation on cycling performance. Med Sci Sports Exerc 2012; 44: 1545-1551.
    • (2012) Med Sci Sports Exerc , vol.44 , pp. 1545-1551
    • Bellinger, P.M.1    Howe, S.T.2    Shing, C.M.3    Fell, J.W.4
  • 33
    • 84904389181 scopus 로고    scopus 로고
    • The effect of b-alanine and NaHCO3 co-ingestion on buffering capacity and exercise performance with high-intensity exercise in healthy males
    • Danaher J, Gerber T, Wellard RM, Stathis CG. The effect of b-alanine and NaHCO3 co-ingestion on buffering capacity and exercise performance with high-intensity exercise in healthy males. Eur J Appl Physiol 2014; 114: 1715-1724.
    • (2014) Eur J Appl Physiol , vol.114 , pp. 1715-1724
    • Danaher, J.1    Gerber, T.2    Wellard, R.M.3    Stathis, C.G.4
  • 34
    • 84880777194 scopus 로고    scopus 로고
    • Additive effects of betaalanine and sodium bicarbonate on upper-body intermittent performance
    • Tobias G, Benatti FB, de Salles Painelli V, et al. Additive effects of betaalanine and sodium bicarbonate on upper-body intermittent performance. Amino Acids 2013; 45: 309-317.
    • (2013) Amino Acids , vol.45 , pp. 309-317
    • Tobias, G.1    Benatti, F.B.2    De Salles Painelli, V.3
  • 35
    • 84900426077 scopus 로고    scopus 로고
    • Effect of sodium bicarbonate and betaalanine on repeated sprints during intermittent exercise performed in hypoxia
    • Saunders B, Sale C, Harris RC, et al. Effect of sodium bicarbonate and betaalanine on repeated sprints during intermittent exercise performed in hypoxia. Int J Sport Nutr Exerc Metab 2014; 24: 196-205.
    • (2014) Int J Sport Nutr Exerc Metab , vol.24 , pp. 196-205
    • Saunders, B.1    Sale, C.2    Harris, R.C.3
  • 36
    • 84885711135 scopus 로고    scopus 로고
    • Physiology and pathophysiology of carnosine
    • Boldyrev AA, Aldini G, Derave W. Physiology and pathophysiology of carnosine. Physiol Rev 2013; 93: 1803-1845.
    • (2013) Physiol Rev , vol.93 , pp. 1803-1845
    • Boldyrev, A.A.1    Aldini, G.2    Derave, W.3
  • 37
    • 80053929408 scopus 로고    scopus 로고
    • Effects of sprint training combined with vegetarian or mixed diet on muscle carnosine content and buffering capacity
    • Baguet A, Everaert I, De Naeyer H, et al. Effects of sprint training combined with vegetarian or mixed diet on muscle carnosine content and buffering capacity. Eur J Appl Physiol 2011; 111: 2571-2580.
    • (2011) Eur J Appl Physiol , vol.111 , pp. 2571-2580
    • Baguet, A.1    Everaert, I.2    De Naeyer, H.3
  • 38
    • 84895909357 scopus 로고    scopus 로고
    • Effects of beta-alanine supplementation and interval training on physiological determinants of severe exercise performance
    • Gross M, Boesch C, Bolliger CS, et al. Effects of beta-alanine supplementation and interval training on physiological determinants of severe exercise performance. Eur J Appl Physiol 2014; 114: 221-234.
    • (2014) Eur J Appl Physiol , vol.114 , pp. 221-234
    • Gross, M.1    Boesch, C.2    Bolliger, C.S.3
  • 39
    • 84859616913 scopus 로고    scopus 로고
    • Effects of carnosine on contractile apparatus Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in human skeletal muscle fibers
    • Dutka TL, Lamboley CR, McKenna MJ, et al. Effects of carnosine on contractile apparatus Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in human skeletal muscle fibers. J Appl Physiol (1985) 2012; 112: 728-736.
    • (2012) J Appl Physiol (1985) , vol.112 , pp. 728-736
    • Dutka, T.L.1    Lamboley, C.R.2    McKenna, M.J.3
  • 40
    • 84871609750 scopus 로고    scopus 로고
    • Effect of beta-alanine and carnosine supplementation on muscle contractility in mice
    • Everaert I, Stegen S, Vanheel B, et al. Effect of beta-alanine and carnosine supplementation on muscle contractility in mice. Med Sci Sports Exerc 2013; 45: 43-51.
    • (2013) Med Sci Sports Exerc , vol.45 , pp. 43-51
    • Everaert, I.1    Stegen, S.2    Vanheel, B.3
  • 41
    • 84878454612 scopus 로고    scopus 로고
    • Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling
    • Swietach P, Youm J-B, Saegusa N, et al. Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling. Proc Natl Acad Sci U S A 2013; 110: E2064-E2073.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. E2064-E2073
    • Swietach, P.1    Youm, J.-B.2    Saegusa, N.3
  • 42
    • 84905263937 scopus 로고    scopus 로고
    • Pumping Ca2+ ions up H+ gradients: A cytoplasmic Ca2+/H+ exchanger without a membrane
    • Swietach P, Leem C-H, Spitzer KW, Vaughan-Jones RD. Pumping Ca2+ ions up H+ gradients: A cytoplasmic Ca2+/H+ exchanger without a membrane. J Physiol 2014; 592: 3179-3188.
    • (2014) J Physiol , vol.592 , pp. 3179-3188
    • Swietach, P.1    Leem, C.-H.2    Spitzer, K.W.3    Vaughan-Jones, R.D.4
  • 43
    • 84862765959 scopus 로고    scopus 로고
    • Beta-alanine (CarnosynTM) supplementation in elderly subjects (60-80 years): Effects on muscle carnosine content and physical capacity
    • Del Favero S, Roschel H, Solis MY, et al. Beta-alanine (CarnosynTM) supplementation in elderly subjects (60-80 years): Effects on muscle carnosine content and physical capacity. Amino Acids 2012; 43: 49-56.
    • (2012) Amino Acids , vol.43 , pp. 49-56
    • Del Favero, S.1    Roschel, H.2    Solis, M.Y.3
  • 44
    • 84880804255 scopus 로고    scopus 로고
    • Oral nutritional supplement fortified with beta-alanine improves physical working capacity in older adults: A randomized, placebo-controlled study
    • McCormack WP, Stout JR, Emerson NS, et al. Oral nutritional supplement fortified with beta-alanine improves physical working capacity in older adults: A randomized, placebo-controlled study. Exp Gerontol 2013; 48: 933-939.
    • (2013) Exp Gerontol , vol.48 , pp. 933-939
    • McCormack, W.P.1    Stout, J.R.2    Emerson, N.S.3
  • 45
    • 84862632622 scopus 로고    scopus 로고
    • Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans
    • Everaert I, Taes Y, De Heer E, et al. Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans. Am J Physiol Renal Physiol 2012; 302: F1537-F1544.
    • (2012) Am J Physiol Renal Physiol , vol.302 , pp. F1537-F1544
    • Everaert, I.1    Taes, Y.2    De Heer, E.3
  • 46
    • 84901251815 scopus 로고    scopus 로고
    • Does low serum carnosinase activity favor high-intensity exercise capacity?
    • Baguet A, Everaert I, Yard B, et al. Does low serum carnosinase activity favor high-intensity exercise capacity? J Appl Physiol 2014; 116: 553-559.
    • (2014) J Appl Physiol , vol.116 , pp. 553-559
    • Baguet, A.1    Everaert, I.2    Yard, B.3
  • 47
    • 79957651591 scopus 로고    scopus 로고
    • The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats
    • Aldini G, Orioli M, Rossoni G, et al. The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats. J Cell Mol Med 2011; 15: 1339-1354.
    • (2011) J Cell Mol Med , vol.15 , pp. 1339-1354
    • Aldini, G.1    Orioli, M.2    Rossoni, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.