Metabolite proofreading in carnosine and homocarnosine synthesis: Molecular identification of PM20D2 as β-alanyl-lysine dipeptidase

Journal of Biological Chemistry

Volumn 289, Issue 28, 2014, Pages 19726-19736

  Veiga da Cunha, Maria ^a   Chevalier, Nathalie ^a   Stroobant, Vincent ^a   Vertommen, Didier ^a   Van Schaftingen, Emile ^a  

^a DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BIOMOLECULES; BRAIN; ENZYME ACTIVITY; MAMMALS; MASS SPECTROMETRY; METABOLITES; MUSCLE; PEPTIDES; PURIFICATION; REPAIR; SUBSTRATES;

ACTIVITY PROFILE; CO-TRANSFECTIONS; MASS SPECTROMETRY ANALYSIS; METALLOPEPTIDASES; MOLECULAR IDENTIFICATION; RADIOLABELED SUBSTRATES; RAT SKELETAL MUSCLE; WESTERN BLOTTING;

BIOMARKERS;

BETA ALANYLLYSINE; BETA ALANYLLYSINE DIPEPTIDASE; BETA ALANYLORNITHINE; CARNOSINE; DIPEPTIDASE; GAMMA AMINOBUTYRYLLYSINE; GAMMA AMINOBUTYRYLORNITHINE; HOMOCARNOSINE; LYSINE; ORNITHINE; PM20D2 PEPTIDASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ASSAY; ENZYME LOCALIZATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HYDROLYSIS; MALE; MOLECULAR DYNAMICS; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

BRAIN METABOLISM; CARNOSINE; CARNS1; CNDP1; HOMOCARNOSINE; M20 METALLOPEPTIDASE; METABOLISM; PEPTIDASE; PEPTIDES; SKELETAL MUSCLE METABOLISM;

ANIMALS; CARNOSINE; DIPEPTIDASES; DIPEPTIDES; HEK293 CELLS; HUMANS; MASS SPECTROMETRY; MICE; ORGAN SPECIFICITY; PEPTIDE SYNTHASES; RATS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84904194388     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.576579     Document Type: Article

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