Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Kast, Jessica ^a   Hanecker, Patrizia ^a   Beaufort, Nathalie ^a   Giese, Armin ^c   Joutel, Anne ^d,e   Dichgans, Martin ^a,b   Opherk, Christian ^a   Haffner, Christof ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Technische Universität München Munich Cluster for Systems Neurology   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d INSERM   (France)

^e UMR S1161   (France)

Author keywords

CADASIL; Extracellular matrix (ECM); Granular osmiophilic material (GOM); Latent TGF binding protein 1 (LTBP 1); Small vessel disease; TGF signaling

Indexed keywords

LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN; LTBP1 PROTEIN, HUMAN; NOTCH RECEPTOR; NOTCH3 PROTEIN, HUMAN;

BRAIN; CADASIL; CASE CONTROL STUDY; FEMALE; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HUMAN; MALE; METABOLISM; MUTATION; NONPARAMETRIC TEST; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; SILVER STAINING;

BRAIN; CADASIL; CASE-CONTROL STUDIES; FEMALE; HEK293 CELLS; HUMANS; LATENT TGF-BETA BINDING PROTEINS; MALE; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SEQUENCE ANALYSIS, PROTEIN; SILVER STAINING; STATISTICS, NONPARAMETRIC; TRANSFECTION;

EID: 84915761982     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-014-0096-8     Document Type: Review

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