메뉴 건너뛰기




Volumn 45, Issue 4, 2015, Pages 1215-1221

Cerebral small vessel disease: Insights and opportunities from mouse models of collagen IV-related small vessel disease and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; COLLAGEN TYPE 4 ALPHA 1; COLLAGEN TYPE 4 ALPHA 2; UNCLASSIFIED DRUG;

EID: 84897451255     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002878     Document Type: Article
Times cited : (71)

References (56)
  • 1
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol. 2010;9:689-701.
    • (2010) Lancet Neurol. , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 2
    • 84876488222 scopus 로고    scopus 로고
    • Mechanisms of sporadic cerebral small vessel disease: Insights from neuroimaging
    • Wardlaw JM, Smith C, Dichgans M. Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging. Lancet Neurol. 2013;12:483-497.
    • (2013) Lancet Neurol. , vol.12 , pp. 483-497
    • Wardlaw, J.M.1    Smith, C.2    Dichgans, M.3
  • 3
    • 84880391350 scopus 로고    scopus 로고
    • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
    • Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, et al.; Standards for Reporting Vascular Changes on Neuroimaging (STRIVE v1). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013;12:822-838.
    • (2013) Lancet Neurol. , vol.12 , pp. 822-838
    • Wardlaw, J.M.1    Smith, E.E.2    Biessels, G.J.3    Cordonnier, C.4    Fazekas, F.5    Frayne, R.6
  • 5
    • 67349216125 scopus 로고    scopus 로고
    • Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies
    • Revesz T, Holton JL, Lashley T, Plant G, Frangione B, Rostagno A, et al. Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies. Acta Neuropathol. 2009;118:115-130.
    • (2009) Acta Neuropathol. , vol.118 , pp. 115-130
    • Revesz, T.1    Holton, J.L.2    Lashley, T.3    Plant, G.4    Frangione, B.5    Rostagno, A.6
  • 8
    • 35548969443 scopus 로고    scopus 로고
    • Glial regulation of the cerebral microvascu-lature
    • Iadecola C, Nedergaard M. Glial regulation of the cerebral microvascu-lature. Nat Neurosci. 2007;10:1369-1376.
    • (2007) Nat Neurosci. , vol.10 , pp. 1369-1376
    • Iadecola, C.1    Nedergaard, M.2
  • 9
    • 84880839631 scopus 로고    scopus 로고
    • Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke
    • Chen ZL, Yao Y, Norris EH, Kruyer A, Jno-Charles O, Akhmerov A, et al. Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke. J Cell Biol. 2013;202:381-395.
    • (2013) J Cell Biol. , vol.202 , pp. 381-395
    • Chen, Z.L.1    Yao, Y.2    Norris, E.H.3    Kruyer, A.4    Jno-Charles, O.5    Akhmerov, A.6
  • 10
    • 84856930011 scopus 로고    scopus 로고
    • The cerebral circulation
    • Granger DN, Granger J, eds. San Rafael, CA: Morgan & Claypool Life Sciences
    • Cipolla MJ The cerebral circulation. In: Granger DN, Granger J, eds. Integrated Systems Physiology: From Molecule to Function. San Rafael, CA: Morgan & Claypool Life Sciences; 2010:1-59.
    • (2010) Integrated Systems Physiology: From Molecule to Function , pp. 1-59
    • Cipolla, M.J.1
  • 11
    • 84888019151 scopus 로고    scopus 로고
    • The pathobiology of vascular dementia
    • Iadecola C. The pathobiology of vascular dementia. Neuron. 2013;80:844-866.
    • (2013) Neuron. , vol.80 , pp. 844-866
    • Iadecola, C.1
  • 12
    • 78650645093 scopus 로고    scopus 로고
    • Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain
    • Fernández-Klett F, Offenhauser N, Dirnagl U, Priller J, Lindauer U. Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proc Natl Acad Sci U S A 2010;107:22290-22295.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22290-22295
    • Fernández-Klett, F.1    Offenhauser, N.2    Dirnagl, U.3    Priller, J.4    Lindauer, U.5
  • 13
    • 77950657947 scopus 로고    scopus 로고
    • Potassium channels and neurovascular coupling
    • Dunn KM, Nelson MT. Potassium channels and neurovascular coupling. Circ J. 2010;74:608-616.
    • (2010) Circ J. , vol.74 , pp. 608-616
    • Dunn, K.M.1    Nelson, M.T.2
  • 14
    • 0021134245 scopus 로고
    • Increased venous pressure causes myogenic constriction of cerebral arterioles during local hyperoxia
    • Wei E P, Kontos HA. Increased venous pressure causes myogenic constriction of cerebral arterioles during local hyperoxia. Circ Res. 1984;55:249-252.
    • (1984) Circ Res. , vol.55 , pp. 249-252
    • Wei, E.P.1    Kontos, H.A.2
  • 15
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegen-erative disorders
    • Zlokovic BV The blood-brain barrier in health and chronic neurodegen-erative disorders. Neuron. 2008;57:178-201.
    • (2008) Neuron. , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 18
    • 79955770689 scopus 로고    scopus 로고
    • Protecting against vascular disease in brain
    • Faraci FM Protecting against vascular disease in brain. Am J Physiol Heart Circ Physiol. 2011;300:H1566-H1582.
    • (2011) Am J Physiol Heart Circ Physiol. , vol.300 , pp. H1566-H1582
    • Faraci, F.M.1
  • 19
    • 84886389767 scopus 로고    scopus 로고
    • Hypertension: A harbinger of stroke and dementia
    • Faraco G, Iadecola C. Hypertension: a harbinger of stroke and dementia. Hypertension. 2013;62:810-817.
    • (2013) Hypertension , vol.62 , pp. 810-817
    • Faraco, G.1    Iadecola, C.2
  • 20
    • 84874562000 scopus 로고    scopus 로고
    • Effects of angiotensin II on the cerebral circulation: Role of oxidative stress
    • De Silva TM, Faraci FM. Effects of angiotensin II on the cerebral circulation: role of oxidative stress. Front Physiol. 2012;3:484.
    • (2012) Front Physiol. , vol.3 , pp. 484
    • De Silva, T.M.1    Faraci, F.M.2
  • 21
    • 84867578043 scopus 로고    scopus 로고
    • Pre-clinical models of human cerebral small vessel disease: Utility for clinical application
    • Hainsworth AH, Brittain JF, Khatun H. Pre-clinical models of human cerebral small vessel disease: utility for clinical application. J Neurol Sci. 2012;322:237-240.
    • (2012) J Neurol Sci. , vol.322 , pp. 237-240
    • Hainsworth, A.H.1    Brittain, J.F.2    Khatun, H.3
  • 22
    • 80053196178 scopus 로고    scopus 로고
    • Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review
    • Bailey EL, Smith C, Sudlow CL, Wardlaw JM. Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review. Int J Stroke. 2011;6:434-444.
    • (2011) Int J Stroke , vol.6 , pp. 434-444
    • Bailey, E.L.1    Smith, C.2    Sudlow, C.L.3    Wardlaw, J.M.4
  • 25
    • 1842482987 scopus 로고    scopus 로고
    • Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
    • Pöschl E, Schlötzer-Schrehardt U, Brachvogel B, Saito K, Ninomiya Y, Mayer U. Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development. 2004;131:1619-1628.
    • (2004) Development , vol.131 , pp. 1619-1628
    • Pöschl, E.1    Schlötzer-Schrehardt, U.2    Brachvogel, B.3    Saito, K.4    Ninomiya, Y.5    Mayer, U.6
  • 28
    • 84867124426 scopus 로고    scopus 로고
    • COL4A1 and COL4A2 mutations and disease: Insights into pathogenic mechanisms and potential therapeutic targets
    • Kuo DS, Labelle-Dumais C, Gould DB. COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets. Hum Mol Genet. 2012;21(R1):R97-R110.
    • (2012) Hum Mol Genet. , vol.21 , Issue.R1 , pp. R97-R110
    • Kuo, D.S.1    Labelle-Dumais, C.2    Gould, D.B.3
  • 31
    • 78651387761 scopus 로고    scopus 로고
    • Clinical spectrum of type IV collagen (COL4A1) mutations: A novel genetic multisystem disease
    • Vahedi K, Alamowitch S. Clinical spectrum of type IV collagen (COL4A1) mutations: a novel genetic multisystem disease. Curr Opin Neurol. 2011;24:63-68.
    • (2011) Curr Opin Neurol. , vol.24 , pp. 63-68
    • Vahedi, K.1    Alamowitch, S.2
  • 32
    • 84878874902 scopus 로고    scopus 로고
    • Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: A new pathomechanism in CADASIL
    • Monet-Leprêtre M, Haddad I, Baron-Menguy C, Fouillot-Panchal M, Riani M, Domenga-Denier V, et al. Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL. Brain. 2013;136(pt 6):1830-1845.
    • (2013) Brain , vol.136 , pp. 1830-1845
    • Monet-Leprêtre, M.1    Haddad, I.2    Baron-Menguy, C.3    Fouillot-Panchal, M.4    Riani, M.5    Domenga-Denier, V.6
  • 33
    • 78649983227 scopus 로고    scopus 로고
    • Pathogenesis of CADASIL: Transgenic and knock-out mice to probe function and dysfunction of the mutated gene, Notch3, in the cere-brovasculature
    • Joutel A. Pathogenesis of CADASIL: transgenic and knock-out mice to probe function and dysfunction of the mutated gene, Notch3, in the cere-brovasculature. Bioessays. 2011;33:73-80.
    • (2011) Bioessays , vol.33 , pp. 73-80
    • Joutel, A.1
  • 34
    • 76649118089 scopus 로고    scopus 로고
    • Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease
    • Joutel A, Monet-Leprêtre M, Gosele C, Baron-Menguy C, Hammes A, Schmidt S, et al. Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease. J Clin Invest. 2010;120:433-445.
    • (2010) J Clin Invest. , vol.120 , pp. 433-445
    • Joutel, A.1    Monet-Leprêtre, M.2    Gosele, C.3    Baron-Menguy, C.4    Hammes, A.5    Schmidt, S.6
  • 35
    • 84862939642 scopus 로고    scopus 로고
    • High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6
    • Zhang L, Lim SL, Du H, Zhang M, Kozak I, Hannum G, et al. High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6. J Biol Chem. 2012;287:1520-1526.
    • (2012) J Biol Chem. , vol.287 , pp. 1520-1526
    • Zhang, L.1    Lim, S.L.2    Du, H.3    Zhang, M.4    Kozak, I.5    Hannum, G.6
  • 36
    • 84897494657 scopus 로고    scopus 로고
    • Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation
    • Graham JR, Chamberland A, Lin Q, Li XJ, Dai D, Zeng W, et al. Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formation. PLoS One. 2013;8:e74094.
    • (2013) PLoS One , vol.8
    • Graham, J.R.1    Chamberland, A.2    Lin, Q.3    Li, X.J.4    Dai, D.5    Zeng, W.6
  • 37
    • 34447336145 scopus 로고    scopus 로고
    • Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis
    • Gould DB, Marchant JK, Savinova OV, Smith RS, John SW. Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis. Hum Mol Genet. 2007;16:798-807.
    • (2007) Hum Mol Genet. , vol.16 , pp. 798-807
    • Gould, D.B.1    Marchant, J.K.2    Savinova, O.V.3    Smith, R.S.4    John, S.W.5
  • 39
    • 77950666806 scopus 로고    scopus 로고
    • Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume
    • Van Agtmael T, Bailey MA, Schlötzer-Schrehardt U, Craigie E, Jackson IJ, Brownstein DG, et al. Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume. Hum Mol Genet. 2010;19:1119-1128.
    • (2010) Hum Mol Genet. , vol.19 , pp. 1119-1128
    • Van Agtmael, T.1    Bailey, M.A.2    Schlötzer-Schrehardt, U.3    Craigie, E.4    Jackson, I.J.5    Brownstein, D.G.6
  • 40
    • 0036019164 scopus 로고    scopus 로고
    • CADASIL: A common form of hereditary arteriopathy causing brain infarcts and dementia
    • Kalimo H, Ruchoux MM, Viitanen M, Kalaria RN. CADASIL: a common form of hereditary arteriopathy causing brain infarcts and dementia. Brain Pathol. 2002;12:371-384.
    • (2002) Brain Pathol. , vol.12 , pp. 371-384
    • Kalimo, H.1    Ruchoux, M.M.2    Viitanen, M.3    Kalaria, R.N.4
  • 41
    • 7644244605 scopus 로고    scopus 로고
    • White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion
    • Shibata M, Ohtani R, Ihara M, Tomimoto H. White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion. Stroke. 2004;35:2598-2603.
    • (2004) Stroke , vol.35 , pp. 2598-2603
    • Shibata, M.1    Ohtani, R.2    Ihara, M.3    Tomimoto, H.4
  • 42
    • 79952490984 scopus 로고    scopus 로고
    • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression
    • Eikermann-Haerter K, Yuzawa I, Dilekoz E, Joutel A, Moskowitz MA, Ayata C. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression. Ann Neurol. 2011;69:413-418.
    • (2011) Ann Neurol. , vol.69 , pp. 413-418
    • Eikermann-Haerter, K.1    Yuzawa, I.2    Dilekoz, E.3    Joutel, A.4    Moskowitz, M.A.5    Ayata, C.6
  • 43
    • 65949097072 scopus 로고    scopus 로고
    • Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease
    • Hara K, Shiga A, Fukutake T, Nozaki H, Miyashita A, Yokoseki A, et al. Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease. N Engl J Med. 2009;360:1729-1739.
    • (2009) N Engl J Med. , vol.360 , pp. 1729-1739
    • Hara, K.1    Shiga, A.2    Fukutake, T.3    Nozaki, H.4    Miyashita, A.5    Yokoseki, A.6
  • 45
    • 84903545868 scopus 로고    scopus 로고
    • Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke
    • Murray LS, Lu Y, Taggart A, Van Regemorter N, Vilain C, Abramowicz M, et al. Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke. Hum Mol Genet. 2014;23:283-292.
    • (2014) Hum Mol Genet. , vol.23 , pp. 283-292
    • Murray, L.S.1    Lu, Y.2    Taggart, A.3    Van Regemorter, N.4    Vilain, C.5    Abramowicz, M.6
  • 46
    • 34548334617 scopus 로고    scopus 로고
    • C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy
    • Richards A, van den Maagdenberg AM, Jen JC, Kavanagh D, Bertram P, Spitzer D, et al. C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy. Nat Genet. 2007;39:1068-1070.
    • (2007) Nat Genet. , vol.39 , pp. 1068-1070
    • Richards, A.1    Van Den Maagdenberg, A.M.2    Jen, J.C.3    Kavanagh, D.4    Bertram, P.5    Spitzer, D.6
  • 49
    • 84859823928 scopus 로고    scopus 로고
    • The matri-some: In silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices
    • Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO. The matri-some: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol Cell Proteomics. 2012;11:M111.014647.
    • (2012) Mol Cell Proteomics , vol.11
    • Naba, A.1    Clauser, K.R.2    Hoersch, S.3    Liu, H.4    Carr, S.A.5    Hynes, R.O.6
  • 50
    • 84904470135 scopus 로고    scopus 로고
    • Archetypal Arg169Cys mutation in NOTCH3 does not drive the pathogenesis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy via a loss-of-function mechanism
    • January 14 Accessed January 14, 2014
    • Cognat E, Baron-Menguy C, Domenga-Denier V, Cleophax S, Fouillade C, Monet-Leprêtre M, et al. Archetypal Arg169Cys mutation in NOTCH3 does not drive the pathogenesis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy via a loss-of-function mechanism. Stroke. January 14, 2014. http://strokeahajournals.org/content/early/recent. Accessed January 14, 2014.
    • (2014) Stroke
    • Cognat, E.1    Baron-Menguy, C.2    Domenga-Denier, V.3    Cleophax, S.4    Fouillade, C.5    Monet-Leprêtre, M.6
  • 51
    • 84883333125 scopus 로고    scopus 로고
    • Incident lacunes preferentially localize to the edge of white matter hyperintensities: Insights into the pathophysiology of cerebral small vessel disease
    • Duering M, Csanadi E, Gesierich B, Jouvent E, Hervé D, Seiler S, et al. Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel disease. Brain. 2013;136(pt 9):2717-2726.
    • (2013) Brain , vol.136 , pp. 2717-2726
    • Duering, M.1    Csanadi, E.2    Gesierich, B.3    Jouvent, E.4    Hervé, D.5    Seiler, S.6
  • 52
    • 33846185489 scopus 로고    scopus 로고
    • Genetics of ischaemic stroke
    • Dichgans M. Genetics of ischaemic stroke. Lancet Neurol. 2007;6:149-161.
    • (2007) Lancet Neurol. , vol.6 , pp. 149-161
    • Dichgans, M.1
  • 53
    • 77951131269 scopus 로고    scopus 로고
    • Mendelian disorders and multifactorial traits: The big divide or one for all?
    • Antonarakis SE, Chakravarti A, Cohen JC, Hardy J. Mendelian disorders and multifactorial traits: the big divide or one for all? Nat Rev Genet. 2010;11:380-384.
    • (2010) Nat Rev Genet. , vol.11 , pp. 380-384
    • Antonarakis, S.E.1    Chakravarti, A.2    Cohen, J.C.3    Hardy, J.4
  • 54
    • 81055147238 scopus 로고    scopus 로고
    • Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease
    • Schmidt H, Zeginigg M, Wiltgen M, Freudenberger P, Petrovic K, Cavalieri M, et al.; CHARGE Consortium Neurology Working Group. Genetic variants of the NOTCH3 gene in the elderly and magnetic resonance imaging correlates of age-related cerebral small vessel disease. Brain. 2011;134(pt 11):3384-3397.
    • (2011) Brain , vol.134 , pp. 3384-3397
    • Schmidt, H.1    Zeginigg, M.2    Wiltgen, M.3    Freudenberger, P.4    Petrovic, K.5    Cavalieri, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.