β-catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy

Journal of the Royal Society Interface

Volumn 12, Issue 102, 2015, Pages

  Banerji, Christopher R S ^a,b,c   Knopp, Paul ^c   Moyle, Louise A ^c   Severini, Simone ^b   Orrell, Richard W ^d   Teschendorff, Andrew E ^a,e   Zammit, Peter S ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e Chinese Academy of Sciences   (China)

Author keywords

Canonical Wnt signalling; Differential networks; DUX4; Facioscapulohumeral muscular dystrophy; Meta analysis; catenin

Indexed keywords

MICROARRAYS; MUSCLE; PROTEINS;

DIFFERENTIAL NETWORK; DUX4; META-ANALYSIS; MUSCULAR DYSTROPHY; WNT SIGNALLING;

TRANSCRIPTION;

BETA CATENIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DUX4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT PROTEIN; CTNNB1 PROTEIN, MOUSE; DUX4 PROTEIN, MOUSE; HIF1A PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETIC ALGORITHM; GENETIC ASSOCIATION; INTERACTOME SPARSIFICATION AND REWIRING ALGORITHM; MICROARRAY ANALYSIS; MOUSE; MUSCLE BIOPSY; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; TRANSCRIPTION INITIATION; WNT SIGNALING PATHWAY; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; BIOPSY; CYTOLOGY; GENE EXPRESSION REGULATION; HUMAN; META ANALYSIS; METABOLISM; MUSCLE; PATHOLOGY; PHYSIOLOGY; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; BETA CATENIN; BIOPSY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MAP KINASE KINASE 4; MICE; MODELS, BIOLOGICAL; MODELS, STATISTICAL; MUSCLES; MUSCULAR DYSTROPHY, FACIOSCAPULOHUMERAL; MYOBLASTS; PHENOTYPE; PROTEIN INTERACTION MAPPING; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84915757705     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0797     Document Type: Article

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