Intrinsic Epigenetic Regulation of the D4Z4 Macrosatellite Repeat in a Transgenic Mouse Model for FSHD

PLoS Genetics

Volumn 9, Issue 4, 2013, Pages

  Krom, Yvonne D ^a   Thijssen, Peter E ^a   Young, Janet M ^b   den Hamer, Bianca ^a   Balog, Judit ^a   Yao, Zizhen ^b   Maves, Lisa ^b   Snider, Lauren ^b   Knopp, Paul ^c   Zammit, Peter S ^c   Rijkers, Tonnie ^a   van Engelen, Baziel G M ^d   Padberg, George W ^d   Frants, Rune R ^a   Tawil, Rabi ^e   Tapscott, Stephen J ^b   van der Maarel, Silvère M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Fred Hutchinson Cancer Research Center   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA STRUCTURE; DUX4 GENE; EMBRYO; EPIGENETIC REPRESSION; FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY; GENE; GENE EXPRESSION; GERM LINE; HUMAN; HUMAN CELL; MACROSATELLITE REPEAT; MOLECULAR MECHANICS; MOUSE; MUSCLE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; TRANSGENIC MOUSE;

ANIMALS; CELLS, CULTURED; CHROMATIN; DISEASE MODELS, ANIMAL; DNA METHYLATION; EMBRYONIC DEVELOPMENT; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, FACIOSCAPULOHUMERAL; REPETITIVE SEQUENCES, NUCLEIC ACID;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 84876821220     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003415     Document Type: Article

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