Global metabolomic and isobaric tagging capillary liquid chromatography-tandem mass spectrometry approaches for uncovering pathway dysfunction in diabetic mouse aorta

Journal of Proteome Research

Volumn 13, Issue 12, 2014, Pages 6121-6134

  Filla, Laura A ^a   Yuan, Wei ^b,c   Feldman, Eva L ^d   Li, Shuwei ^b,c   Edwards, James L ^a  

^a Saint Louis University   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c Bldg 142   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

capillary liquid chromatography; diabetes; diabetic complications; global metabolomics; isobaric tags; metabolic pathway dysfunction; tandem mass spectrometry

Indexed keywords

AMINE; CARBONYL DERIVATIVE; PYRIDOXINE; AMINO ACID; BIOLOGICAL MARKER; BUTYRIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL INJURY; CAPILLARY LIQUID CHROMATOGRAPHY; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DIABETES MELLITUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERGLYCEMIA; HYPERLIPIDEMIA; HYPERTENSION; LIQUID CHROMATOGRAPHY; METABOLOMICS; MOUSE; NONHUMAN; OXIDATIVE STRESS; TANDEM MASS SPECTROMETRY; VASCULAR TISSUE; ANIMAL; DIABETIC ANGIOPATHY; ISOTOPE LABELING; KNOCKOUT MOUSE; METABOLISM; METABOLOME; PROCEDURES;

AMINES; AMINO ACIDS; ANIMALS; AORTA; BIOMARKERS; BUTYRATES; CARBOHYDRATE METABOLISM; CHROMATOGRAPHY, LIQUID; DIABETIC ANGIOPATHIES; HYPERGLYCEMIA; ISOTOPE LABELING; METABOLIC NETWORKS AND PATHWAYS; METABOLOME; METABOLOMICS; MICE, KNOCKOUT; PROPIONATES; TANDEM MASS SPECTROMETRY; VITAMIN B 6;

EID: 84915749800     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr501030e     Document Type: Article

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