Stability of bovine lactoferrin in luminal extracts and mucosal homogenates from rat intestine: A prelude to oral absorption

Chemical Biology and Drug Design

Volumn 84, Issue 6, 2014, Pages 676-684

  Yao, Xudong ^a   Bunt, Craig ^b   Cornish, Jillian ^c   Quek, Siew Young ^a   Wen, Jingyuan ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b LINCOLN UNIVERSITY   (New Zealand)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Bovine lactoferrin; Enzyme inhibitor; Particulate delivery system; Proteolysis; Pseudo first order rate

Indexed keywords

AMINOPEPTIDASE LIKE PROTEASE; BACITRACIN; BESTATIN; BOVINE LACTOFERRIN; DEOXYCHOLATE SODIUM; ENZYME; LACTOFERRIN; LIPOSOME; PEPTIDASE; POLYMER; PROTEINASE; SOLID LIPID NANOPARTICLE; SOYBEAN TRYPSIN INHIBITOR; TRYPTASE; UNCLASSIFIED DRUG; ENZYME INHIBITOR;

ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CONTROLLED STUDY; DEGRADATION KINETICS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HYDROLYSIS; DRUG STABILITY; DUODENUM; ENCAPSULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ILEUM; INTESTINE FLUID; INTESTINE MUCOSA; JEJUNUM; MALE; NANOPHARMACEUTICS; NONHUMAN; PROTEIN DEGRADATION; RAT; REDUCTION KINETICS; TISSUE HOMOGENATE; ANIMAL; BOVINE; DRUG EFFECTS; ENZYMOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE; KINETICS; METABOLISM; ORAL DRUG ADMINISTRATION; PROTEIN STABILITY; WISTAR RAT;

BOVINAE; RATTUS;

ADMINISTRATION, ORAL; ANIMALS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; INTESTINAL MUCOSA; INTESTINES; KINETICS; LACTOFERRIN; MALE; PROTEIN STABILITY; PROTEOLYSIS; RATS; RATS, WISTAR;

EID: 84915737421     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12360     Document Type: Article

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