메뉴 건너뛰기




Volumn 251, Issue 1-2, 2006, Pages 96-102

Lactoferrin potently inhibits osteoblast apoptosis, via an LRP1-independent pathway

Author keywords

Apoptosis; Lactoferrin; LRP1; Osteoblast

Indexed keywords

LACTOFERRICIN; LIPOPROTEIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 33646550545     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.03.002     Document Type: Article
Times cited : (74)

References (36)
  • 2
    • 0032893748 scopus 로고    scopus 로고
    • Lactoferrin: a multifunctional glycoprotein involved in the modulation of the inflammatory process
    • Baveye S., Elass E., Mazurier J., Spik G., and Legrand D. Lactoferrin: a multifunctional glycoprotein involved in the modulation of the inflammatory process. Clin. Chem. Lab. Med. 37 (1999) 281-286
    • (1999) Clin. Chem. Lab. Med. , vol.37 , pp. 281-286
    • Baveye, S.1    Elass, E.2    Mazurier, J.3    Spik, G.4    Legrand, D.5
  • 3
    • 0037013188 scopus 로고    scopus 로고
    • Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low density lipoprotein receptor-related protein in caveolae
    • Boucher P., Liu P., Gotthardt M., Hiesberger T., Anderson R.G., and Herz J. Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low density lipoprotein receptor-related protein in caveolae. J. Biol. Chem. 277 (2002) 15507-15513
    • (2002) J. Biol. Chem. , vol.277 , pp. 15507-15513
    • Boucher, P.1    Liu, P.2    Gotthardt, M.3    Hiesberger, T.4    Anderson, R.G.5    Herz, J.6
  • 4
    • 0031923160 scopus 로고    scopus 로고
    • Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family
    • Bu G.J. Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family. Curr. Opin. Lipidol. 9 (1998) 149-155
    • (1998) Curr. Opin. Lipidol. , vol.9 , pp. 149-155
    • Bu, G.J.1
  • 6
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: a play in three Akts
    • Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 (1999) 2905-2927
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 7
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok V., Voelker D., Campbell P., Cohen J., Bratton D., and Henson P. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148 (1992) 2207-2216
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.1    Voelker, D.2    Campbell, P.3    Cohen, J.4    Bratton, D.5    Henson, P.6
  • 8
    • 6444230922 scopus 로고    scopus 로고
    • Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats
    • Fujita K., Matsuda E., Sekine K., Iigo M., and Tsuda H. Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats. Carcinogenesis 25 (2004) 1961-1966
    • (2004) Carcinogenesis , vol.25 , pp. 1961-1966
    • Fujita, K.1    Matsuda, E.2    Sekine, K.3    Iigo, M.4    Tsuda, H.5
  • 9
    • 4344590829 scopus 로고    scopus 로고
    • Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat
    • Fujita K., Matsuda E., Sekine K., Iigo M., and Tsuda H. Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat. Cancer Lett. 213 (2004) 21-29
    • (2004) Cancer Lett. , vol.213 , pp. 21-29
    • Fujita, K.1    Matsuda, E.2    Sekine, K.3    Iigo, M.4    Tsuda, H.5
  • 10
    • 15944406764 scopus 로고    scopus 로고
    • PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
    • Gao T., Furnari F., and Newton A.C. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol. Cell. 18 (2005) 13-24
    • (2005) Mol. Cell. , vol.18 , pp. 13-24
    • Gao, T.1    Furnari, F.2    Newton, A.C.3
  • 11
    • 0031729124 scopus 로고    scopus 로고
    • Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
    • Goetzl E.J., and An S. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12 (1998) 1589-1598
    • (1998) FASEB J. , vol.12 , pp. 1589-1598
    • Goetzl, E.J.1    An, S.2
  • 12
    • 18044386744 scopus 로고    scopus 로고
    • Gong, Y., Slee, R.B., Fukai, N., Rawadi, G., Roman-Roman, S., Reginato, A.M., Wang, H., Cundy, T., Glorieux, F.H., Lev, D., Zacharin, M., Oexle, K., Marcelino, J., Suwairi, W., Heeger, S., Sabatakos, G., Apte, S., Adkins, W.N., Allgrove, J., Arslan-Kirchner, M., Batch, J.A., Beighton, P., Black, G.C., Boles, R.G., Boon, L.M., Borrone, C., Brunner, H.G., Carle, G.F., Dallapiccola, B., De Paepe, A., Floege, B., Halfhide, M.L., Hall, B., Hennekam, R.C., Hirose, T., Jans, A., Juppner, H., Kim, C.A., Keppler-Noreuil, K., Kohlschuetter, A., LaCombe, D., Lambert, M., Lemyre, E., Letteboer, T., Peltonen, L., Ramesar, R.S., Romanengo, M., Somer, H., Steichen-Gersdorf, E., Steinmann, B., Sullivan, B., Superti-Furga, A., Swoboda, W., van den Boogaard, M.J., Van Hul, W., Vikkula, M., Votruba, M., Zabel, B., Garcia, T., Baron, R., Olsen, B.R., Warman, M.L.,Osteoporosis-Pseudoglioma Syndrome Collaborative G., 2001. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell, 107, 513-523.
  • 13
    • 0035095485 scopus 로고    scopus 로고
    • Lysophosphatidic acid is an osteoblast mitogen whose proliferative actions involve G(i) proteins and protein kinase C, but not p42/44 mitogen-activated protein kinases
    • Grey A., Banovic T., Naot D., Hill B., Callon K., Reid I., and Cornish J. Lysophosphatidic acid is an osteoblast mitogen whose proliferative actions involve G(i) proteins and protein kinase C, but not p42/44 mitogen-activated protein kinases. Endocrinology 142 (2001) 1098-1106
    • (2001) Endocrinology , vol.142 , pp. 1098-1106
    • Grey, A.1    Banovic, T.2    Naot, D.3    Hill, B.4    Callon, K.5    Reid, I.6    Cornish, J.7
  • 15
    • 0036893646 scopus 로고    scopus 로고
    • The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving G(i) proteins and phosphatidylinositol-3 kinase
    • Grey A., Chen Q., Callon K., Xu X., Reid I.R., and Cornish J. The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving G(i) proteins and phosphatidylinositol-3 kinase. Endocrinology 143 (2002) 4755-4763
    • (2002) Endocrinology , vol.143 , pp. 4755-4763
    • Grey, A.1    Chen, Q.2    Callon, K.3    Xu, X.4    Reid, I.R.5    Cornish, J.6
  • 16
    • 0242721096 scopus 로고    scopus 로고
    • Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells
    • Grey A., Chen Q., Xu X., Callon K., and Cornish J. Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells. Endocrinology 144 (2003) 4886-4893
    • (2003) Endocrinology , vol.144 , pp. 4886-4893
    • Grey, A.1    Chen, Q.2    Xu, X.3    Callon, K.4    Cornish, J.5
  • 20
    • 18544378303 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function between LRP and the PDGF
    • Loukinova E., Ranganathan S., Kuznetsov S., Gorlatova N., Migliorini M.M., Loukinov D., Ulery P.G., Mikhailenko I., Lawrence D.A., and Strickland D.K. Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function between LRP and the PDGF. J. Biol. Chem. 277 (2002) 15499-15506
    • (2002) J. Biol. Chem. , vol.277 , pp. 15499-15506
    • Loukinova, E.1    Ranganathan, S.2    Kuznetsov, S.3    Gorlatova, N.4    Migliorini, M.M.5    Loukinov, D.6    Ulery, P.G.7    Mikhailenko, I.8    Lawrence, D.A.9    Strickland, D.K.10
  • 21
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • Manolagas S.C. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr. Rev. 21 (2000) 115-137
    • (2000) Endocr. Rev. , vol.21 , pp. 115-137
    • Manolagas, S.C.1
  • 22
    • 0033604620 scopus 로고    scopus 로고
    • Bioactive lysophospholipids and their G protein-coupled receptors
    • Moolenaar W.H. Bioactive lysophospholipids and their G protein-coupled receptors. Exp. Cell Res. 253 (1999) 230-238
    • (1999) Exp. Cell Res. , vol.253 , pp. 230-238
    • Moolenaar, W.H.1
  • 23
    • 12544260025 scopus 로고    scopus 로고
    • Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K-1 to bone
    • Niemeier A., Kassem M., Toedter K., Wendt D., Ruether W., Beisiegel U., and Heeren J. Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K-1 to bone. J. Bone Miner. Res. 20 (2005) 283-293
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 283-293
    • Niemeier, A.1    Kassem, M.2    Toedter, K.3    Wendt, D.4    Ruether, W.5    Beisiegel, U.6    Heeren, J.7
  • 25
    • 0036187820 scopus 로고    scopus 로고
    • Characterization of mammalian receptors for lactoferrin
    • Suzuki Y.A., and Lonnerdal B. Characterization of mammalian receptors for lactoferrin. Biochem. Cell Biol. 80 (2002) 75-80
    • (2002) Biochem. Cell Biol. , vol.80 , pp. 75-80
    • Suzuki, Y.A.1    Lonnerdal, B.2
  • 26
    • 0035951070 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a human intestinal lactoferrin receptor
    • Suzuki Y.A., Shin K., and Lonnerdal B. Molecular cloning and functional expression of a human intestinal lactoferrin receptor. Biochemistry (Mosc.) 40 (2001) 15771-15779
    • (2001) Biochemistry (Mosc.) , vol.40 , pp. 15771-15779
    • Suzuki, Y.A.1    Shin, K.2    Lonnerdal, B.3
  • 27
    • 0038158309 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts
    • Takayama Y., Takahashi H., Mizumachi K., and Takezawa T. Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts. J. Biol. Chem. 278 (2003) 22112-22118
    • (2003) J. Biol. Chem. , vol.278 , pp. 22112-22118
    • Takayama, Y.1    Takahashi, H.2    Mizumachi, K.3    Takezawa, T.4
  • 28
    • 0037865435 scopus 로고    scopus 로고
    • Characteristics of lactoferrin receptor in bovine intestine: higher binding activity to the epithelium overlying Peyer's patches
    • Talukder M.J., Takeuchi T., and Harada E. Characteristics of lactoferrin receptor in bovine intestine: higher binding activity to the epithelium overlying Peyer's patches. J. Vet. Med., Ser. A 50 (2003) 123-131
    • (2003) J. Vet. Med., Ser. A , vol.50 , pp. 123-131
    • Talukder, M.J.1    Takeuchi, T.2    Harada, E.3
  • 29
    • 17644416374 scopus 로고    scopus 로고
    • Inhibitory activity of bovine lactoferrin against echovirus induced programmed cell death in vitro
    • Tinari A., Pietrantoni A., Ammendolia M.G., Valenti P., and Superti F. Inhibitory activity of bovine lactoferrin against echovirus induced programmed cell death in vitro. Int. J. Antimicrob. Agents 25 (2005) 433-438
    • (2005) Int. J. Antimicrob. Agents , vol.25 , pp. 433-438
    • Tinari, A.1    Pietrantoni, A.2    Ammendolia, M.G.3    Valenti, P.4    Superti, F.5
  • 30
    • 0036188351 scopus 로고    scopus 로고
    • Cancer prevention by bovine lactoferrin and underlying mechanisms-a review of experimental and clinical studies
    • Tsuda H., Sekine K., Fujita K., and Ligo M. Cancer prevention by bovine lactoferrin and underlying mechanisms-a review of experimental and clinical studies. Biochem. Cell Biol. 80 (2002) 131-136
    • (2002) Biochem. Cell Biol. , vol.80 , pp. 131-136
    • Tsuda, H.1    Sekine, K.2    Fujita, K.3    Ligo, M.4
  • 31
    • 0034493814 scopus 로고    scopus 로고
    • Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin in animals
    • Tsuda H., Sekine K., Takasuka N., Toriyama-Baba H., and Iigo M. Prevention of colon carcinogenesis and carcinoma metastasis by orally administered bovine lactoferrin in animals. Biofactors 12 (2000) 83-88
    • (2000) Biofactors , vol.12 , pp. 83-88
    • Tsuda, H.1    Sekine, K.2    Takasuka, N.3    Toriyama-Baba, H.4    Iigo, M.5
  • 32
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone
    • Weinstein R.S., Jilka R.L., Parfitt A.M., and Manolagas S.C. Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. J. Clin. Invest. 102 (1998) 274-282
    • (1998) J. Clin. Invest. , vol.102 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Parfitt, A.M.3    Manolagas, S.C.4
  • 34
    • 0027079937 scopus 로고
    • Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance
    • Willnow T.E., Goldstein J.L., Orth K., Brown M.S., and Herz J. Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. J. Biol. Chem. 267 (1992) 26172-26180
    • (1992) J. Biol. Chem. , vol.267 , pp. 26172-26180
    • Willnow, T.E.1    Goldstein, J.L.2    Orth, K.3    Brown, M.S.4    Herz, J.5
  • 35
    • 10044274113 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation
    • Yang M., Huang H., Li J., Li D., and Wang H. Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation. FASEB J. 18 (2004) 1920-1921
    • (2004) FASEB J. , vol.18 , pp. 1920-1921
    • Yang, M.1    Huang, H.2    Li, J.3    Li, D.4    Wang, H.5
  • 36
    • 17844382139 scopus 로고    scopus 로고
    • G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the beta-catenin pathway
    • Yang M., Zhong W.W., Srivastava N., Slavin A., Yang J.X., Hoey T., and An S.Z. G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the beta-catenin pathway. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 6027-6032
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 6027-6032
    • Yang, M.1    Zhong, W.W.2    Srivastava, N.3    Slavin, A.4    Yang, J.X.5    Hoey, T.6    An, S.Z.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.