Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  van Dis, Vera ^a   Kuijpers, Marijn ^a,b   Haasdijk, Elize D ^a   Teuling, Eva ^a   Oakes, Scott A ^c   Hoogenraad, Casper C ^a,b   Jaarsma, Dick ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyotrophic lateral sclerosis (ALS); Dynein; Endosome trafficking; Protein aggregation; SOD1; Transgenic mouse model

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ATF3 PROTEIN, MOUSE; CALCITONIN GENE RELATED PEPTIDE; CARRIER PROTEIN; CHOLERA TOXIN; CHOLINE ACETYLTRANSFERASE; EARLY ENDOSOME ANTIGEN 1; MEMBRANE PROTEIN; NERVE PROTEIN; SOD1 G93A PROTEIN; SUPEROXIDE DISMUTASE; TAMALIN PROTEIN, MOUSE; VESICULAR TRANSPORT PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; CELL CULTURE; COMPLICATION; DISEASE MODEL; ENDOSOME; GENETICS; GOLGI COMPLEX; HUMAN; METABOLISM; MOTONEURON; MOUSE; NEUROMUSCULAR DISEASES; PATHOLOGY; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ACTIVATING TRANSCRIPTION FACTOR 3; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CARRIER PROTEINS; CELLS, CULTURED; CHOLERA TOXIN; CHOLINE O-ACETYLTRANSFERASE; DISEASE MODELS, ANIMAL; ENDOSOMES; GOLGI APPARATUS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; NERVE TISSUE PROTEINS; NEUROMUSCULAR DISEASES; SUPEROXIDE DISMUTASE; VESICULAR TRANSPORT PROTEINS;

EID: 84914669403     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-2-38     Document Type: Article

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