Disruption of the structure of the Golgi apparatus and the function of the secretory pathway by mutants G93A and G85R of Cu, Zn superoxide dismutase (SOD1) of familial amyotrophic lateral sclerosis

Journal of the Neurological Sciences

Volumn 219, Issue 1-2, 2004, Pages 45-53

  Stieber, Anna ^a   Gonatas, J O ^a   Moore, J S ^a   Bantly, Andrew ^a   Yim, H S ^b   Yim, M B ^b   Gonatas, N K ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c Dr Ralph Sallie Weaver Prof R ^*  (United States)

Author keywords

Amyotrophic lateral sclerosis; Golgi apparatus

Indexed keywords

COPPER; GLYCOPROTEIN; MUTANT PROTEIN; SUPEROXIDE DISMUTASE; ZINC;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL FUNCTION; CELL SURFACE; CELL SURVIVAL; CYTOPLASM; DISEASE COURSE; FAMILIAL DISEASE; GOLGI COMPLEX; HAMSTER; HUMAN; IN VITRO STUDY; INTERMETHOD COMPARISON; MEASUREMENT; MOTONEURON; MOUSE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN SECRETION; SURVIVAL; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL SURVIVAL; CHO CELLS; CRICETINAE; GOLGI APPARATUS; HUMANS; MUTAGENESIS; POINT MUTATION; SECRETORY VESICLES; SUPEROXIDE DISMUTASE;

EID: 1642528556     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2003.12.004     Document Type: Article

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