XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats

Journal of Neurochemistry

Volumn 123, Issue 3, 2012, Pages 406-416

  Tong, Jianbin ^a   Huang, Cao ^a   Bi, Fangfang ^a   Wu, Qinxue ^a   Huang, Bo ^a   Zhou, Hongxia ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Golgi fragmentation; rats; TDP 43; ubiquitin aggregation; XBP1

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CHAPERONE; INOSITOL REQUIRING PROTEIN 1; MUTANT PROTEIN; PROTEIN KINASE R RELATED ENDOPLASMIC RETICULUM KINASE; SIGNAL PEPTIDE; TAR DNA BINDING PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FOREBRAIN; GOLGI COMPLEX; GOLGI COMPLEX FRAGMENTATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; TRANSGENIC RAT; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

AGE FACTORS; ANIMALS; CELL DEATH; DENDRITES; DNA-BINDING PROTEINS; FRONTOTEMPORAL LOBAR DEGENERATION; GOLGI APPARATUS; HUMANS; MEMORY DISORDERS; NERVE DEGENERATION; NEUROGLIA; NEURONS; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; TDP-43 PROTEINOPATHIES; TRANSCRIPTION FACTORS; UBIQUITIN; UNFOLDED PROTEIN RESPONSE;

EID: 84867289633     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12014     Document Type: Article

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