Endoplasmic reticulum stress sensor protein kinase R-like endoplasmic reticulum kinase (PERK) protects against pressure overload-induced heart failure and lung remodeling

Hypertension

Volumn 64, Issue 4, 2014, Pages 738-744

  Liu, Xiaoyu ^a,b   Kwak, Dongmin ^b   Lu, Zhongbing ^b,c   Xu, Xin ^b   Fassett, John ^b   Wang, Huan ^b   Wei, Yidong ^a   Cavener, Douglas R ^d   Hu, Xinli ^e   Hall, Jennifer ^b   Bache, Robert J ^b   Chen, Yingjie ^b  

^a TONGJI UNIVERSITY   (China)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

^e PEKING UNIVERSITY   (China)

Author keywords

Calcium dynamics; Cardiomyocytes; Congestive heart failure; Endoplasmic reticulum; ER stress; PERK protein; Sarcoplasmic endoplasmic reticulum calcium ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); DDIT3 PROTEIN, MOUSE; GLUCOSE-REGULATED PROTEINS; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; INITIATION FACTOR 2; MEMBRANE PROTEIN; MOLECULAR CHAPERONE GRP78; PERK KINASE; PROTEIN KINASE R;

ANIMAL; AORTA; APOPTOSIS; CARDIOMEGALY; ENDOPLASMIC RETICULUM STRESS; ENZYMOLOGY; FEMALE; FIBROSIS; GENETICS; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; KNOCKOUT MOUSE; LIGATION; LUNG; METABOLISM; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PRESSURE; SARCOPLASMIC RETICULUM; WEIGHT BEARING; WESTERN BLOTTING;

ANIMALS; AORTA; APOPTOSIS; BLOTTING, WESTERN; CALCIUM-TRANSPORTING ATPASES; CARDIOMEGALY; CONSTRICTION; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; FEMALE; FIBROSIS; HEART FAILURE; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; LUNG; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MYOCARDIUM; PHOSPHORYLATION; PRESSURE; SARCOPLASMIC RETICULUM; TRANSCRIPTION FACTOR CHOP; VENTRICULAR DYSFUNCTION, LEFT; WEIGHT-BEARING;

EID: 84914158052     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03811     Document Type: Article

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