-
1
-
-
84873034262
-
Proteotoxicity and cardiac dysfunction-Alzheimer's disease of the heart?
-
Willis MS, Patterson C (2013) Proteotoxicity and cardiac dysfunction-Alzheimer's disease of the heart? N Engl J Med 368(5):455-464.
-
(2013)
N Engl J Med
, vol.368
, Issue.5
, pp. 455-464
-
-
Willis, M.S.1
Patterson, C.2
-
2
-
-
84872611623
-
Mammalian heart renewal by pre-existing cardiomyocytes
-
Senyo SE, et al. (2013) Mammalian heart renewal by pre-existing cardiomyocytes. Nature 493(7432):433-436.
-
(2013)
Nature
, vol.493
, Issue.7432
, pp. 433-436
-
-
Senyo, S.E.1
-
3
-
-
79952065525
-
Transient regenerative potential of the neonatal mouse heart
-
Porrello ER, et al. (2011) Transient regenerative potential of the neonatal mouse heart. Science 331(6020):1078-1080.
-
(2011)
Science
, vol.331
, Issue.6020
, pp. 1078-1080
-
-
Porrello, E.R.1
-
4
-
-
41449086790
-
Cardiac plasticity
-
Hill JA, Olson EN (2008) Cardiac plasticity. N Engl J Med 358(13):1370-1380.
-
(2008)
N Engl J Med
, vol.358
, Issue.13
, pp. 1370-1380
-
-
Hill, J.A.1
Olson, E.N.2
-
5
-
-
34447133404
-
Cardiac autophagy is a maladaptive response to hemodynamic stress
-
Zhu H, et al. (2007) Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest 117(7):1782-1793.
-
(2007)
J Clin Invest
, vol.117
, Issue.7
, pp. 1782-1793
-
-
Zhu, H.1
-
6
-
-
47749105267
-
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
-
Tannous P, et al. (2008) Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 117(24):3070-3078.
-
(2008)
Circulation
, vol.117
, Issue.24
, pp. 3070-3078
-
-
Tannous, P.1
-
7
-
-
17344361902
-
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy
-
Vicart P, et al. (1998) A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat Genet 20(1):92-95.
-
(1998)
Nat Genet
, vol.20
, Issue.1
, pp. 92-95
-
-
Vicart, P.1
-
8
-
-
0242637569
-
AlphaB-crystallin modulates protein aggregation of abnormal desmin
-
Wang X, et al. (2003) AlphaB-crystallin modulates protein aggregation of abnormal desmin. Circ Res 93(10):998-1005.
-
(2003)
Circ Res
, vol.93
, Issue.10
, pp. 998-1005
-
-
Wang, X.1
-
9
-
-
0035816115
-
Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice
-
Wang X, et al. (2001) Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice. Circ Res 89(1):84-91.
-
(2001)
Circ Res
, vol.89
, Issue.1
, pp. 84-91
-
-
Wang, X.1
-
10
-
-
80053286909
-
Desmin-related cardiomyopathy: An unfolding story
-
McLendon PM, Robbins J (2011) Desmin-related cardiomyopathy: An unfolding story. Am J Physiol Heart Circ Physiol 301(4):H1220-H1228.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, Issue.4
, pp. H1220-H1228
-
-
McLendon, P.M.1
Robbins, J.2
-
11
-
-
68849104798
-
Tragedy in a heartbeat: Malfunctioning desmin causes skeletal and cardiac muscle disease
-
Goldfarb LG, Dalakas MC (2009) Tragedy in a heartbeat: Malfunctioning desmin causes skeletal and cardiac muscle disease. J Clin Invest 119(7):1806-1813.
-
(2009)
J Clin Invest
, vol.119
, Issue.7
, pp. 1806-1813
-
-
Goldfarb, L.G.1
Dalakas, M.C.2
-
12
-
-
0036872241
-
Desmin cytoskeleton: A potential regulator of muscle mitochondrial behavior and function
-
Capetanaki Y (2002) Desmin cytoskeleton: A potential regulator of muscle mitochondrial behavior and function. Trends Cardiovasc Med 12(8):339-348.
-
(2002)
Trends Cardiovasc Med
, vol.12
, Issue.8
, pp. 339-348
-
-
Capetanaki, Y.1
-
13
-
-
0032586878
-
Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function
-
Bova MP, et al. (1999) Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function. Proc Natl Acad Sci USA 96(11):6137-6142.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.11
, pp. 6137-6142
-
-
Bova, M.P.1
-
14
-
-
33644874959
-
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in a-B-crystallin desmin-related cardiomyopathy
-
Maloyan A, et al. (2005) Mitochondrial dysfunction and apoptosis underlie the pathogenic process in a-B-crystallin desmin-related cardiomyopathy. Circulation 112(22):3451-3461.
-
(2005)
Circulation
, vol.112
, Issue.22
, pp. 3451-3461
-
-
Maloyan, A.1
-
15
-
-
77952427302
-
Manipulation of death pathways in desmin-related cardiomyopathy
-
Maloyan A, Sayegh J, Osinska H, Chua BHL, Robbins J (2010) Manipulation of death pathways in desmin-related cardiomyopathy. Circ Res 106(9):1524-1532.
-
(2010)
Circ Res
, vol.106
, Issue.9
, pp. 1524-1532
-
-
Maloyan, A.1
Sayegh, J.2
Osinska, H.3
Bhl, C.4
Robbins, J.5
-
16
-
-
3042711961
-
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
-
Sanbe A, et al. (2004) Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis. Proc Natl Acad Sci USA 101(27):10132-10136.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.27
, pp. 10132-10136
-
-
Sanbe, A.1
-
17
-
-
79960342396
-
Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes
-
Pattison JS, Osinska H, Robbins J (2011) Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes. Circ Res 109(2):151-160.
-
(2011)
Circ Res
, vol.109
, Issue.2
, pp. 151-160
-
-
Pattison, J.S.1
Osinska, H.2
Robbins, J.3
-
18
-
-
27944450427
-
Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake
-
Chen Q, et al. (2005) Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake. Circ Res 97(10): 1018-1026.
-
(2005)
Circ Res
, vol.97
, Issue.10
, pp. 1018-1026
-
-
Chen, Q.1
-
19
-
-
0036951869
-
Desmin filaments and cardiac disease: Establishing causality
-
Wang X, Osinska H, Gerdes AM, Robbins J (2002) Desmin filaments and cardiac disease: Establishing causality. J Card Fail 8(6, Suppl):S287-S292.
-
(2002)
J Card Fail
, vol.8
, Issue.6
, pp. S287-S292
-
-
Wang, X.1
Osinska, H.2
Gerdes, A.M.3
Robbins, J.4
-
20
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin
-
Iwata A, Riley BE, Johnston JA, Kopito RR (2005) HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin. J Biol Chem 280(48): 40282-40292.
-
(2005)
J Biol Chem
, vol.280
, Issue.48
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
21
-
-
77954935925
-
Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation
-
Geeraert C, et al. (2010) Starvation-induced hyperacetylation of tubulin is required for the stimulation of autophagy by nutrient deprivation. J Biol Chem 285(31): 24184-24194.
-
(2010)
J Biol Chem
, vol.285
, Issue.31
, pp. 24184-24194
-
-
Geeraert, C.1
-
22
-
-
84877909895
-
Autophagy and microtubules: New story, old players
-
Mackeh R, Perdiz D, Lorin S, Codogno P, Poüs C (2013) Autophagy and microtubules: New story, old players. J Cell Sci 126(Pt 5):1071-1080.
-
(2013)
J Cell Sci
, vol.126
, pp. 1071-1080
-
-
Mackeh, R.1
Perdiz, D.2
Lorin, S.3
Codogno, P.4
Poüs, C.5
-
23
-
-
33745173485
-
Suppression of class i and II histone deacetylases blunts pressure-overload cardiac hypertrophy
-
Kong Y, et al. (2006) Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation 113(22):2579-2588.
-
(2006)
Circulation
, vol.113
, Issue.22
, pp. 2579-2588
-
-
Kong, Y.1
-
24
-
-
84895923936
-
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy
-
Xie M, et al. (2014) Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 129(10):1139-1151.
-
(2014)
Circulation
, vol.129
, Issue.10
, pp. 1139-1151
-
-
Xie, M.1
-
25
-
-
54049090410
-
Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice
-
Granger A, et al. (2008) Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. FASEB J 22(10):3549-3560.
-
(2008)
FASEB J
, vol.22
, Issue.10
, pp. 3549-3560
-
-
Granger, A.1
-
26
-
-
84863231352
-
Selective class i histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
-
Cavasin MA, et al. (2012) Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism. Circ Res 110(5):739-748.
-
(2012)
Circ Res
, vol.110
, Issue.5
, pp. 739-748
-
-
Ma, C.1
-
27
-
-
84867837864
-
HDAC inhibitor modulation of proteotoxicity as a therapeutic approach in cancer
-
McConkey DJ, White M, Yan W (2012) HDAC inhibitor modulation of proteotoxicity as a therapeutic approach in cancer. Adv Cancer Res 116:131-163.
-
(2012)
Adv Cancer Res
, vol.116
, pp. 131-163
-
-
McConkey, D.J.1
White, M.2
Yan, W.3
-
28
-
-
57749170458
-
The many roles of histone deacety-lases in development and physiology: Implications for disease and therapy
-
Haberland M, Montgomery RL, Olson EN (2009) The many roles of histone deacety-lases in development and physiology: Implications for disease and therapy. Nat Rev Genet 10(1):32-42.
-
(2009)
Nat Rev Genet
, vol.10
, Issue.1
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
29
-
-
35548942629
-
Inhibition of histone de-acetylases triggers pharmacologic preconditioning effects against myocardial ische-mic injury
-
Zhao TC, Cheng G, Zhang LX, Tseng YT, Padbury JF (2007) Inhibition of histone de-acetylases triggers pharmacologic preconditioning effects against myocardial ische-mic injury. Cardiovasc Res 76(3):473-481.
-
(2007)
Cardiovasc Res
, vol.76
, Issue.3
, pp. 473-481
-
-
Zhao, T.C.1
Cheng, G.2
Zhang, L.X.3
Tseng, Y.T.4
Padbury, J.F.5
-
30
-
-
79952775153
-
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
-
Cao DJ, et al. (2011) Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc Natl Acad Sci USA 108(10):4123-4128.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.10
, pp. 4123-4128
-
-
Cao, D.J.1
-
31
-
-
84860915669
-
HDAC6 at the intersection of neu-roprotection and neurodegeneration
-
d'Ydewalle C, Bogaert E, Van Den Bosch L (2012) HDAC6 at the intersection of neu-roprotection and neurodegeneration. Traffic 13(6):771-779.
-
(2012)
Traffic
, vol.13
, Issue.6
, pp. 771-779
-
-
D'Ydewalle, C.1
Bogaert, E.2
Van Den Bosch, L.3
-
32
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
Kawaguchi Y, et al. (2003) The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 115(6):727-738.
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 727-738
-
-
Kawaguchi, Y.1
-
33
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey UB, et al. (2007) HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 447(7146):859-863.
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 859-863
-
-
Pandey, U.B.1
-
34
-
-
84873173538
-
Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes
-
Li Y, Shin D, Kwon SH (2013) Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes. FEBS J 280(3):775-793.
-
(2013)
FEBS J
, vol.280
, Issue.3
, pp. 775-793
-
-
Li, Y.1
Shin, D.2
Kwon, S.H.3
-
35
-
-
77956410115
-
Selective autophagy: Ubiquitin-mediated recognition and beyond
-
Kraft C, Peter M, Hofmann K (2010) Selective autophagy: Ubiquitin-mediated recognition and beyond. Nat Cell Biol 12(9):836-841.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.9
, pp. 836-841
-
-
Kraft, C.1
Peter, M.2
Hofmann, K.3
-
36
-
-
34548851476
-
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
-
Olzmann JA, et al. (2007) Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. J Cell Biol 178(6):1025-1038.
-
(2007)
J Cell Biol
, vol.178
, Issue.6
, pp. 1025-1038
-
-
Olzmann, J.A.1
-
37
-
-
79956317095
-
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension
-
Lemon DD, et al. (2011) Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol 51(1):41-50.
-
(2011)
J Mol Cell Cardiol
, vol.51
, Issue.1
, pp. 41-50
-
-
Lemon, D.D.1
-
38
-
-
84904293106
-
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling
-
Demos-Davies KM, et al. (2014) HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling. Am J Physiol Heart Circ Physiol 307(2):H252-H258.
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.307
, Issue.2
, pp. H252-H258
-
-
Demos-Davies, K.M.1
-
39
-
-
84880036835
-
HDAC-dependent ventricular remodeling
-
Xie M, Hill JA (2013) HDAC-dependent ventricular remodeling. Trends Cardiovasc Med 23(6):229-235.
-
(2013)
Trends Cardiovasc Med
, vol.23
, Issue.6
, pp. 229-235
-
-
Xie, M.1
Hill, J.A.2
-
40
-
-
55749103407
-
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
-
Thomas EA, et al. (2008) The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Proc Natl Acad Sci USA 105(40):15564-15569.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.40
, pp. 15564-15569
-
-
Thomas, E.A.1
-
41
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
Steffan JS, et al. (2001) Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 413(6857):739-743.
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 739-743
-
-
Steffan, J.S.1
-
42
-
-
65449170415
-
Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy
-
Sanbe A, et al. (2009) Protective effect of geranylgeranylacetone via enhancement of HSPB8 induction in desmin-related cardiomyopathy. PLoS ONE 4(4):e5351.
-
(2009)
PLoS ONE
, vol.4
, Issue.4
, pp. e5351
-
-
Sanbe, A.1
-
43
-
-
26444486021
-
Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy
-
Sanbe A, et al. (2005) Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy. Proc Natl Acad Sci USA 102(38):13592-13597.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.38
, pp. 13592-13597
-
-
Sanbe, A.1
-
44
-
-
0037452775
-
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
-
Hockly E, et al. (2003) Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci USA 100(4):2041-2046.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.4
, pp. 2041-2046
-
-
Hockly, E.1
-
45
-
-
84890072367
-
Enhanced autophagy ameliorates cardiac proteinopathy
-
Bhuiyan MS, et al. (2013) Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest 123(12):5284-5297.
-
(2013)
J Clin Invest
, vol.123
, Issue.12
, pp. 5284-5297
-
-
Bhuiyan, M.S.1
-
46
-
-
84865162355
-
P62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress
-
Su H, Wang X (2011) p62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress. Trends Cardiovasc Med 21(8):224-228.
-
(2011)
Trends Cardiovasc Med
, vol.21
, Issue.8
, pp. 224-228
-
-
Su, H.1
Wang, X.2
-
47
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He C, et al. (2012) Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481(7382):511-515.
-
(2012)
Nature
, vol.481
, Issue.7382
, pp. 511-515
-
-
He, C.1
-
48
-
-
34347249232
-
Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomy-opathy
-
Maloyan A, Gulick J, Glabe CG, Kayed R, Robbins J (2007) Exercise reverses preamyloid oligomer and prolongs survival in alphaB-crystallin-based desmin-related cardiomy-opathy. Proc Natl Acad Sci USA 104(14):5995-6000.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.14
, pp. 5995-6000
-
-
Maloyan, A.1
Gulick, J.2
Glabe, C.G.3
Kayed, R.4
Robbins, J.5
-
49
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10(12):524-530.
-
(2000)
Trends Cell Biol
, vol.10
, Issue.12
, pp. 524-530
-
-
Kopito, R.R.1
-
50
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein DC (2006) The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443(7113):780-786.
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
51
-
-
77649202326
-
Protein aggregation diseases: Pathogenicity and therapeutic perspectives
-
Aguzzi A, O'Connor T (2010) Protein aggregation diseases: Pathogenicity and therapeutic perspectives. Nat Rev Drug Discov 9(3):237-248.
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.3
, pp. 237-248
-
-
Aguzzi, A.1
O'Connor, T.2
-
52
-
-
4043171124
-
Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes
-
Hull RL, Westermark GT, Westermark P, Kahn SE (2004) Islet amyloid: A critical entity in the pathogenesis of type 2 diabetes. J Clin Endocrinol Metab 89(8):3629-3643.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.8
, pp. 3629-3643
-
-
Hull, R.L.1
Westermark, G.T.2
Westermark, P.3
Kahn, S.E.4
-
53
-
-
14344283370
-
Mouse model of desmin-related cardiomyopathy
-
Wang X, et al. (2001) Mouse model of desmin-related cardiomyopathy. Circulation 103(19):2402-2407.
-
(2001)
Circulation
, vol.103
, Issue.19
, pp. 2402-2407
-
-
Wang, X.1
-
54
-
-
0035839573
-
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
-
Bulteau A-L, et al. (2001) Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J Biol Chem 276(32):30057-30063.
-
(2001)
J Biol Chem
, vol.276
, Issue.32
, pp. 30057-30063
-
-
Bulteau, A.-L.1
-
55
-
-
14844338880
-
Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants
-
Sarikas A, et al. (2005) Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants. Cardiovasc Res 66(1):33-44.
-
(2005)
Cardiovasc Res
, vol.66
, Issue.1
, pp. 33-44
-
-
Sarikas, A.1
-
56
-
-
84873874848
-
Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4
-
Yi J, et al. (2013) Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4. PLoS ONE 8(1):e54792.
-
(2013)
PLoS ONE
, vol.8
, Issue.1
, pp. e54792
-
-
Yi, J.1
-
57
-
-
34447315270
-
HDAC6 modulates cell motility by altering the acetylation level of cortactin
-
Zhang X, et al. (2007) HDAC6 modulates cell motility by altering the acetylation level of cortactin. Mol Cell 27(2):197-213.
-
(2007)
Mol Cell
, vol.27
, Issue.2
, pp. 197-213
-
-
Zhang, X.1
-
58
-
-
73449117582
-
Immunomodulatory effects of deacetylase inhibitors: Therapeutic targeting of FOXP3+ regulatory T cells
-
Wang L, de Zoeten EF, Greene MI, Hancock WW (2009) Immunomodulatory effects of deacetylase inhibitors: Therapeutic targeting of FOXP3+ regulatory T cells. Nat Rev Drug Discov 8(12):969-981.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.12
, pp. 969-981
-
-
Wang, L.1
De Zoeten, E.F.2
Greene, M.I.3
Hancock, W.W.4
-
59
-
-
84877773314
-
Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons
-
Brochier C, et al. (2013) Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci 33(20):8621-8632.
-
(2013)
J Neurosci
, vol.33
, Issue.20
, pp. 8621-8632
-
-
Brochier, C.1
-
60
-
-
84896773754
-
Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle
-
Winter L, et al. (2014) Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle. J Clin Invest 124(3):1144-1157.
-
(2014)
J Clin Invest
, vol.124
, Issue.3
, pp. 1144-1157
-
-
Winter, L.1
-
61
-
-
77649337122
-
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
-
Lee JY, et al. (2010) HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy. EMBO J 29(5):969-980.
-
(2010)
EMBO J
, vol.29
, Issue.5
, pp. 969-980
-
-
Lee, J.Y.1
-
62
-
-
0344683235
-
-
(National Academies Press, Washington, DC)
-
Committee for the Update of the Guide for the Care and Use of Laboratory Animals (2011) Guide for the Care and Use of Laboratory Animals (National Academies Press, Washington, DC).
-
(2011)
Guide for the Care and Use of Laboratory Animals
-
-
|