Maximizing recombinant human serum albumin production in a Muts Pichia pastoris strain

Biotechnology Progress

Volumn 30, Issue 6, 2014, Pages 1488-1496

  Mallem, Muralidhar ^a,b   Warburton, Shannon ^a,c   Li, Fang ^a   Shandil, Ishaan ^a   Nylen, Adam ^a   Kim, Sehoon ^a   Jiang, Youwei ^a   Meehl, Michael ^a   d'Anjou, Marc ^a   Stadheim, Terrance A ^a   Choi, Byung Kwon ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b SHIRE   (United States)

^c HENRY M JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE   (United States)

Author keywords

Cell density; Human serum albumin; Pichia pastoris muts; Specific growth rate

Indexed keywords

AMINO ACIDS; BODY FLUIDS; CELLS; COMMERCE; CYTOLOGY; METHANOL; OPTIMIZATION; PROCESS CONTROL; PRODUCTIVITY; YEAST;

CELL DENSITY; FERMENTATION PROCESS; HIGH-LEVEL PRODUCTION; HUMAN SERUM ALBUMINS; PICHIA PASTORIS; RECOMBINANT HUMAN SERUM ALBUMIN; SPECIFIC GROWTH RATE; SPECIFIC PRODUCTIVITY;

CELL ENGINEERING;

PICHIA PASTORIS;

RECOMBINANT PROTEIN; SERUM ALBUMIN;

BIOTECHNOLOGY; CHEMISTRY; GENE INACTIVATION; GENETICS; HUMAN; METABOLISM; PHENOTYPE; PICHIA; PROCEDURES;

BIOTECHNOLOGY; GENE KNOCKOUT TECHNIQUES; HUMANS; PHENOTYPE; PICHIA; RECOMBINANT PROTEINS; SERUM ALBUMIN;

EID: 84914112647     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1990     Document Type: Article

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