Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Shpyleva, Svitlana ^a,b   Ivanovsky, Samuil ^b,c   De Conti, Aline ^a   Melnyk, Stepan ^a   Tryndyak, Volodymyr ^b   Beland, Frederick A ^b   James, S Jill ^a   Pogribny, Igor P ^b  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; 8 HYDROXYDEOXYGUANOSINE; 8 OXO 7 HYDRODEOXYGUANOSINE; DNA; DNA GLYCOSYLTRANSFERASE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GENOMIC DNA; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG; CHROMATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; AUTOPSY; CEREBELLUM DISEASE; CONTROLLED STUDY; DNA DAMAGE; DNA ISOLATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE; GENE EXPRESSION; GENOMICS; HUMAN; MALE; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEOMICS; TET1 GENE; TET2 GENE; ANIMAL; CEREBELLUM; CHROMATIN; DISEASE MODEL; DNA MICROARRAY; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; POSTMORTEM CHANGE;

MUS;

ANIMALS; AUTISTIC DISORDER; CEREBELLUM; CHROMATIN; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA METHYLATION; FEMALE; HUMANS; MALE; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATION-REDUCTION; POSTMORTEM CHANGES;

EID: 84913552982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113712     Document Type: Article

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