oh8dG induces G1 arrest in a human acute leukemia cell line by upregulating P21 and blocking the RAS to ERK signaling pathway

International Journal of Cancer

Volumn 118, Issue 2, 2006, Pages 302-309

  Hyun, Jin Won ^a   Yoon, Sun Hee ^b   Yu, Younsil ^b   Han, Chang Soo ^b   Park, Jin Sun ^c   Kim, Hee Sun ^c   Lee, Su Jae ^d   Lee, Yun Sil ^d   You, Ho Jin ^e   Chung, Myung Hee ^b  

^a Jeju National University School of Medicine   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

^d Korea Cancer Center Hospital   (South Korea)

^e Chosun University   (South Korea)

Author keywords

8 hydroxyguanine; Cell cycle; KG 1; OGG1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 8 HYDROXYDEOXYGUANOSINE; 8 OXOGUANINE GLYCOSYLASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; DNA GLYCOSYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN P21; RAS PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG; 8 HYDROXYGUANINE; 8-HYDROXYGUANINE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DRUG DERIVATIVE; GUANINE;

ACUTE LEUKEMIA; APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DNA CONTENT; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INACTIVATION; GENE LOSS; GENE MUTATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOSIS INHIBITION; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ACUTE DISEASE; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; LEUKEMIA; PATHOLOGY; UPREGULATION;

ACUTE DISEASE; APOPTOSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; G1 PHASE; GUANINE; HUMANS; LEUKEMIA; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 28844496593     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.21329     Document Type: Article

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