메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages 1361-1374

JNK Suppresses Tumor Formation via a Gene-Expression Program Mediated by ATF2

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; MESSENGER RNA; RAS PROTEIN;

EID: 84912141151     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.10.043     Document Type: Article
Times cited : (34)

References (51)
  • 1
    • 43049121301 scopus 로고    scopus 로고
    • A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins
    • Arnold H.K., Sears R.C. A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins. Cancer Metastasis Rev. 2008, 27:147-158.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 147-158
    • Arnold, H.K.1    Sears, R.C.2
  • 3
    • 0346365379 scopus 로고    scopus 로고
    • Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival
    • Berger A.J., Kluger H.M., Li N., Kielhorn E., Halaban R., Ronai Z., Rimm D.L. Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. Cancer Res. 2003, 63:8103-8107.
    • (2003) Cancer Res. , vol.63 , pp. 8103-8107
    • Berger, A.J.1    Kluger, H.M.2    Li, N.3    Kielhorn, E.4    Halaban, R.5    Ronai, Z.6    Rimm, D.L.7
  • 6
    • 78751566393 scopus 로고    scopus 로고
    • Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer
    • Calvisi D.F., Ladu S., Conner E.A., Seo D., Hsieh J.T., Factor V.M., Thorgeirsson S.S. Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer. J.Hepatol. 2011, 54:311-319.
    • (2011) J.Hepatol. , vol.54 , pp. 311-319
    • Calvisi, D.F.1    Ladu, S.2    Conner, E.A.3    Seo, D.4    Hsieh, J.T.5    Factor, V.M.6    Thorgeirsson, S.S.7
  • 11
    • 0030706186 scopus 로고    scopus 로고
    • Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway
    • Chow C.W., Rincón M., Cavanagh J., Dickens M., Davis R.J. Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway. Science 1997, 278:1638-1641.
    • (1997) Science , vol.278 , pp. 1638-1641
    • Chow, C.W.1    Rincón, M.2    Cavanagh, J.3    Dickens, M.4    Davis, R.J.5
  • 13
    • 79952595097 scopus 로고    scopus 로고
    • The role of JNK in the development of hepatocellular carcinoma
    • Das M., Garlick D.S., Greiner D.L., Davis R.J. The role of JNK in the development of hepatocellular carcinoma. Genes Dev. 2011, 25:634-645.
    • (2011) Genes Dev. , vol.25 , pp. 634-645
    • Das, M.1    Garlick, D.S.2    Greiner, D.L.3    Davis, R.J.4
  • 14
  • 15
    • 0037462454 scopus 로고    scopus 로고
    • Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
    • Eferl R., Ricci R., Kenner L., Zenz R., David J.P., Rath M., Wagner E.F. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 2003, 112:181-192.
    • (2003) Cell , vol.112 , pp. 181-192
    • Eferl, R.1    Ricci, R.2    Kenner, L.3    Zenz, R.4    David, J.P.5    Rath, M.6    Wagner, E.F.7
  • 16
  • 17
    • 84896134891 scopus 로고    scopus 로고
    • New biological perspectives for the improvement of the efficacy of sorafenib in hepatocellular carcinoma
    • Galmiche A., Chauffert B., Barbare J.C. New biological perspectives for the improvement of the efficacy of sorafenib in hepatocellular carcinoma. Cancer Lett. 2014, 346:159-162.
    • (2014) Cancer Lett. , vol.346 , pp. 159-162
    • Galmiche, A.1    Chauffert, B.2    Barbare, J.C.3
  • 19
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta S., Campbell D., Dérijard B., Davis R.J. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 1995, 267:389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Dérijard, B.3    Davis, R.J.4
  • 22
    • 57449109370 scopus 로고    scopus 로고
    • Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation
    • Hui L., Zatloukal K., Scheuch H., Stepniak E., Wagner E.F. Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation. J.Clin. Invest. 2008, 118:3943-3953.
    • (2008) J.Clin. Invest. , vol.118 , pp. 3943-3953
    • Hui, L.1    Zatloukal, K.2    Scheuch, H.3    Stepniak, E.4    Wagner, E.F.5
  • 23
    • 14644436355 scopus 로고    scopus 로고
    • B-raf and Ha-ras mutations in chemically induced mouse liver tumors
    • Jaworski M., Buchmann A., Bauer P., Riess O., Schwarz M. B-raf and Ha-ras mutations in chemically induced mouse liver tumors. Oncogene 2005, 24:1290-1295.
    • (2005) Oncogene , vol.24 , pp. 1290-1295
    • Jaworski, M.1    Buchmann, A.2    Bauer, P.3    Riess, O.4    Schwarz, M.5
  • 24
    • 61449155619 scopus 로고    scopus 로고
    • Expression and prognostic value of activating transcription factor 2 (ATF2) and its phosphorylated form in mammary carcinomas
    • Knippen S., Löning T., Müller V., Schröder C., Jänicke F., Milde-Langosch K. Expression and prognostic value of activating transcription factor 2 (ATF2) and its phosphorylated form in mammary carcinomas. Anticancer Res. 2009, 29:183-189.
    • (2009) Anticancer Res. , vol.29 , pp. 183-189
    • Knippen, S.1    Löning, T.2    Müller, V.3    Schröder, C.4    Jänicke, F.5    Milde-Langosch, K.6
  • 27
    • 0036269755 scopus 로고    scopus 로고
    • The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
    • Lei K., Nimnual A., Zong W.X., Kennedy N.J., Flavell R.A., Thompson C.B., Bar-Sagi D., Davis R.J. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol. Cell. Biol. 2002, 22:4929-4942.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4929-4942
    • Lei, K.1    Nimnual, A.2    Zong, W.X.3    Kennedy, N.J.4    Flavell, R.A.5    Thompson, C.B.6    Bar-Sagi, D.7    Davis, R.J.8
  • 28
    • 34547642807 scopus 로고    scopus 로고
    • Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A
    • Ma J., Arnold H.K., Lilly M.B., Sears R.C., Kraft A.S. Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A. Oncogene 2007, 26:5145-5153.
    • (2007) Oncogene , vol.26 , pp. 5145-5153
    • Ma, J.1    Arnold, H.K.2    Lilly, M.B.3    Sears, R.C.4    Kraft, A.S.5
  • 30
    • 39149145109 scopus 로고    scopus 로고
    • ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors
    • Maekawa T., Sano Y., Shinagawa T., Rahman Z., Sakuma T., Nomura S., Licht J.D., Ishii S. ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors. Oncogene 2008, 27:1045-1054.
    • (2008) Oncogene , vol.27 , pp. 1045-1054
    • Maekawa, T.1    Sano, Y.2    Shinagawa, T.3    Rahman, Z.4    Sakuma, T.5    Nomura, S.6    Licht, J.D.7    Ishii, S.8
  • 31
    • 77956175013 scopus 로고    scopus 로고
    • NFAT, immunity and cancer: a transcription factor comes of age
    • Müller M.R., Rao A. NFAT, immunity and cancer: a transcription factor comes of age. Nat. Rev. Immunol. 2010, 10:645-656.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 645-656
    • Müller, M.R.1    Rao, A.2
  • 33
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J., Whitmarsh A.J., Barrett T., Dérijard B., Davis R.J. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 1996, 16:1247-1255.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Dérijard, B.4    Davis, R.J.5
  • 34
    • 79951506095 scopus 로고    scopus 로고
    • Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt
    • Rodgers J.T., Vogel R.O., Puigserver P. Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt. Mol. Cell 2011, 41:471-479.
    • (2011) Mol. Cell , vol.41 , pp. 471-479
    • Rodgers, J.T.1    Vogel, R.O.2    Puigserver, P.3
  • 36
    • 33746032571 scopus 로고    scopus 로고
    • Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
    • Sakurai T., Maeda S., Chang L., Karin M. Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation. Proc. Natl. Acad. Sci. USA 2006, 103:10544-10551.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10544-10551
    • Sakurai, T.1    Maeda, S.2    Chang, L.3    Karin, M.4
  • 37
    • 0036497956 scopus 로고    scopus 로고
    • Dysregulation of phosphatidylinositol 3-kinase and downstream effectors in human breast cancer
    • Salh B., Marotta A., Wagey R., Sayed M., Pelech S. Dysregulation of phosphatidylinositol 3-kinase and downstream effectors in human breast cancer. Int. J. Cancer 2002, 98:148-154.
    • (2002) Int. J. Cancer , vol.98 , pp. 148-154
    • Salh, B.1    Marotta, A.2    Wagey, R.3    Sayed, M.4    Pelech, S.5
  • 41
    • 0038296940 scopus 로고    scopus 로고
    • Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2)
    • Steinmüller L., Thiel G. Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2). Biol. Chem. 2003, 384:667-672.
    • (2003) Biol. Chem. , vol.384 , pp. 667-672
    • Steinmüller, L.1    Thiel, G.2
  • 46
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner E.F., Nebreda A.R. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 2009, 9:537-549.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 47
    • 84894597135 scopus 로고    scopus 로고
    • Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2
    • Walczynski J., Lyons S., Jones N., Breitwieser W. Sensitisation of c-MYC-induced B-lymphoma cells to apoptosis by ATF2. Oncogene 2014, 33:1027-1036.
    • (2014) Oncogene , vol.33 , pp. 1027-1036
    • Walczynski, J.1    Lyons, S.2    Jones, N.3    Breitwieser, W.4
  • 48
    • 84871636747 scopus 로고    scopus 로고
    • Calcineurin/NFATc1 pathway contributes to cell proliferation in hepatocellular carcinoma
    • Wang S., Kang X., Cao S., Cheng H., Wang D., Geng J. Calcineurin/NFATc1 pathway contributes to cell proliferation in hepatocellular carcinoma. Dig. Dis. Sci. 2012, 57:3184-3188.
    • (2012) Dig. Dis. Sci. , vol.57 , pp. 3184-3188
    • Wang, S.1    Kang, X.2    Cao, S.3    Cheng, H.4    Wang, D.5    Geng, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.