Inactivation of Ras GTPase-activating proteins promotes unrestrained activity of wild-type Ras in human liver cancer

Journal of Hepatology

Volumn 54, Issue 2, 2011, Pages 311-319

  Calvisi, Diego F ^a,b   Ladu, Sara ^a   Conner, Elizabeth A ^a   Seo, Daekwan ^a   Hsieh, Jer Tsong ^c,d   Factor, Valentina M ^a   Thorgeirsson, Snorri S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF SASSARI   (Italy)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

HCC; Methylation; Ras GAPs

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAS PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER SURVIVAL; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN TISSUE; LIVER CANCER; LIVER CARCINOGENESIS; LIVER RESECTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DNA METHYLATION; HUMANS; LIVER NEOPLASMS; LOSS OF HETEROZYGOSITY; MAP KINASE KINASE KINASE 5; PAIRED BOX TRANSCRIPTION FACTORS; PHOSPHOLIPASE C GAMMA; RAS GTPASE-ACTIVATING PROTEINS; RAS PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 78751566393     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.06.036     Document Type: Article

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