MiR-378 overexpression attenuates high glucose-suppressed osteogenic differentiation through targeting CASP3 and activating PI3k/Akt signaling pathway

International Journal of Clinical and Experimental Pathology

Volumn 7, Issue 10, 2014, Pages 7249-7261

  You, Li ^a   Gu, Wensha ^a   Chen, Lin ^a   Pan, Ling ^a   Chen, Jinyu ^a   Peng, Yongde ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

CASP3; High glucose; Mir 378; Osteogenic differentiation; PI3K Akt signaling

Indexed keywords

ALKALINE PHOSPHATASE; CASP3 PROTEIN, MOUSE; CASPASE 3; COLLAGEN TYPE 1; GLUCOSE; MICRORNA; MIRN378 MICRORNA, MOUSE; OSTEOCALCIN; OSTERIX PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RUNX2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2;

3T3 CELL LINE; ANIMAL; APOPTOSIS; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL SURVIVAL; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; MOUSE; OSTEOBLAST; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME; UPREGULATION;

3T3 CELLS; ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; CALCIFICATION, PHYSIOLOGIC; CASPASE 3; CELL DIFFERENTIATION; CELL SURVIVAL; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE; MALE; MICE; MICRORNAS; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84912133951     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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