Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2

Journal of Cellular Physiology

Volumn 193, Issue 2, 2002, Pages 225-232

  Yuasa, Takahito ^a   Kataoka, Hiroko ^b   Kinto, Naoki ^c   Iwamoto, Masahiro ^d   Enomoto Iwamoto, Motomi ^e   Iemura, Shun Ichiro ^e   Ueno, Naoto ^e   Shibata, Yasuaki ^e   Kurosawa, Hisashi ^e   Yamaguchi, Akira ^a,f  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c Shimane Institute of Health Science   (Japan)

^d NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; MESSENGER RNA; OSTEOCALCIN; RECOMBINANT PROTEIN; SONIC HEDGEHOG PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; IN VITRO STUDY; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ALKALINE PHOSPHATASE; ANIMALS; BONE DEVELOPMENT; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC INDUCTION; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, INBRED C3H; OSTEOBLASTS; OSTEOCALCIN; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; RNA, MESSENGER; TIME FACTORS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTS;

ERINACEIDAE;

EID: 0036836811     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10166     Document Type: Article

References (38)

1. Bitgood MJ, McMahon AP. 1995. Hedgehog and Bmp genes are coexpressed many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol 172:126-138.
2. Brunet LJ, McMahon JA, McMahon AP, Harland RM. 1998. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science 280:1455-1457.
3. Capdevila J, Belmonte JC. 1999. Extracellular modulation of the hedgehog, Wnt, and TGF-β signaling pathways during embryonic development. Curr Opin Gene Dev 9:427-433.
4. Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Wesphal H, Beachy PA. 1996. Cyclopia and defective axial patterning in mice lacking sonic hedgehog gene function. Nature 383:407-413.
5. Chung UI, Lanske B, Lee K, Li E, Kronenberg H. 1998. The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation. Proc Natl Acad Sci USA 95:13030-13035.
6. Dale JK, Vesque C, Lints TJ, Sampath TK, Furley A, Dodd J, Placzek M. 1997. Cooperation of BMP7 and SHH in the induction of forebrain ventral midline cells by prechordal mesiderm. Cell 90:257-269.
7. Enomoto-Iwamoto M, Nakamura T, Aikawa T, Higuchi Y, Yuasa T, Yamaguchi A, Nohno T, Noji S, Matsuya T, Kurisu K, Koyama E, Pacifici M, Iwamoto M. 2000. Hedgehog proteins stimulate chondrogenic cell differentiation and cartilage formation. J Bone Miner Res 15:1659-1668.
8. Ferguson C, Alpern E, Miclau T, Helms JA. 1999. Does adult fracture repair recapitulate embryonic skeletal formation? Mech Dev 87:57-66.
9. Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. 1994. The hedgehog gene family in Drosophila and vertebrate development. Dev Suppl 1994:43-51.
10. Francis PA, Richardson MK, Brickell PM, Tickle C. 1994. Bone morphogenetic proteins and a signaling pathway that controls patterning in the developing chick limb. Development 120:209-218.
11. Hammerschmidt M, Brook A, McMahon AP. 1997. The world according to hedgehog. Trends Genet 13:1-42.
12. Hashimoto J, Yoshikawa H, Takaoka K, Shimizu N, Masuhara K, Tsuda T, Miyamoto S, Ono K. 1990. Inhibitory effects of tumor necrosis factor alpha on fracture healing in rats. Bone 10:453-457.
13. Ishidou Y, Kitajima I, Obama H, Maruyama I, Murata F, Imamura T, Yamada N, ten Dijke P, Miyazono K, Sakou T. 1995. Enhanced expression of type I receptor for bone morphogenetic proteins during bone formation. J Bone Miner Res 10:1651-1659.
14. Ito H, Akiyama H, Shigeno C, Iyama K, Matsuoka H, Nakamura T. 1999. Hedgehog signaling molecules in bone marrow cells at the initial stage of fracture repair. Biochem Biophys Res Commun 262:443-451.
15. Karp SJ, Schipani E, St-Jaques B, Hunzelman J, Kronenberg H, McMahon AP. 2000. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development 127:543-548.
16. Kinto N, Iwamoto M, Enomoto-Iwamoto M, Noji S, Ohuchi H, Yoshioka H, Kataoka H, Wada Y, Yu-Hao G, Takahashi HE, Yoshiki S, Yamaguchi A. 1997. Fibroblasts expressing sonic hedgehog induce osteoblast differentiation and ectopic bone formation. FEBS Lett 404:319-323.
17. Krishnan V, Ma G, Moseley J, Geiser A, Friant S, Frolik C. 2001. Bone anabolic effects of sonic/indian hedgehog are mediated by bmp-2/4-dependent pathways in the neonatal rat metatarsal model. Endocrinology 142:940-947.
18. Lanske B, Karaplis AC, Lee K, Luz A, Vortkamp A, Pirro A, Karperien M, Defize LHK, Ho C, Mulligan R, Abou-Samra AB, Juppner H, Segre GV, Kronenberg HM. 1996. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science 273:663-666.
19. Laufer E, Nelson CE, Johnson RL, Morgan BA, Tabin C. 1994. Sonic hedgehog and FGF-4 acts through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79:993-1003.
20. Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ. 1996a. Biochemical evidence that patched is the hedgehog receptor. Nature 384:176-179.
21. Marigo V, Johnson RL, Vortkam P, Tabin CJ. 1996b. Sonic hedgehog differentially regulates expression of Gli1 and Gli3 during limb development. Dev Biol 180:273-283.
22. Marigo V, Scott MP, Johnson RL, Goodrich LV, Tabin CJ. 1996. Conservation in hedgehog signaling: Induction of a chicken patched homolog by sonic hedgehog in the developing limb. Development 122:1225-1233.
23. McMahon JA, Takada S, Zimmerman LB, Fan CM, Harland RM, McMahon AP. 1998. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev 12:1438-1452.
24. Murtaugh LC, Chyung JH, Lassar AB. 1999. Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. Gene Dev 13:225-237.
25. Nakamura T, Aikawa T, Iwamoto-Enomoto M, Iwamoto M, Higuchi Y, Maurizio P, Kinto N, Yamaguchi A, Noji S, Kurisu K, Matsuya T. 1997. Induction of osteogenic differentiation by hedgehog proteins. Biochem Biophys Res Commun 237:465-469.
26. Nakase T, Nomura S, Yoshikawa H, Hashimoto J, Hirota S, Kitamura Y, Oikawa S, Ono K, Takaoka K. 1994. Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing. J Bone Miner Res 9:651-659.
27. Natsume T, Tomita S, Iemura S, Kinto N, Yamaguchi A, Ueno N. 1997. Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4. J Biol Chem 272:11535-11540.
28. Onishi T, Ishidou Y, Nagamine T, Yone K, Imamura T, Kato M, Sampath TK, ten Dijke P, Sakou T. 1998. Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats. Bone 22:605-612.
29. Pathi S, Rutenbnerg JB, Johnson RL, Vortkamp A. 1999. Interaction of Ihh and BMP/Noggin signaling during cartilage differetiation. Dev Biol 209:239-253.
30. Pathi S, Pagan-Westphal S, Baker DP, Garber EA, Rayhorn P, Bumcrot D, Tabin CJ, Blake Pepinsky R, Williams KP. 2001. Comparative biological responses to human sonic, Indian, and desert hedgehog. Mech Dev 106:107-117.
31. Spinella-Jaegle S, Rawadi G, Kawai S, Gallea S, Faucheu C, Mollat P, Courtois B, Bergaud B, Ramez V, Blanchet AM, Adelmant G, Baron R, Roman-Roman S. 2002. Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation. J Cell Sci 114:2085-2094.
32. St-Jacquea B, Hammerschmidt M, McMahon AP. 1999. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Gene Dev 13:2072-2086.
33. Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T. 1988. Osteoblastic cells are involveed in osteoclast formation. Endocrinology 123:2600-2602.
34. Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ. 1996. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273:613-622.
35. Vortkamp A, Pathi S, Peretti GM, Caruso EM, Zaleske DJ, Tabin CJ. 1998. Recapituration of signals regulating embryonic bone forming during postnatal growth and in fracture repair. Mech Dev 71:65-76.
36. Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S. 1991. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibitsmyogenic differentiation in vitro. J Cell Biol 113:681-687.
37. Yang Y, Drossopoulou G, Chuang PT, Duprez D, Marti E, Bumcrot D, Vargesson N, Clarke J, Niswander L, McMahon A, Tickle C. 1997. Relationship between dose, distance and time in sonic hedgehogmediated regulation of anteroposterior polarity in the chick limb. Development 124:4393-4404.
38. Zimmerman LB, De Jesus-Escobar JM, Harland RM. 1996. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86:599-606.