메뉴 건너뛰기




Volumn 20, Issue 9, 2010, Pages 683-690

Mechanisms of impaired bone strength in type 1 and 2 diabetes

Author keywords

Bone strength; Diabetes; Fracture; Glucose toxicity; Osteoporosis

Indexed keywords

ANTIDIABETIC AGENT;

EID: 78049407620     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2010.07.008     Document Type: Review
Times cited : (96)

References (70)
  • 1
    • 33847629923 scopus 로고    scopus 로고
    • Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a meta-analysis
    • Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a meta-analysis. Osteoporos Int 2007, 18:427-444. 10.1007/s00198-006-0253-4.
    • (2007) Osteoporos Int , vol.18 , pp. 427-444
    • Vestergaard, P.1
  • 2
    • 65749113590 scopus 로고    scopus 로고
    • Glucose toxicity: the leading actor in the pathogenesis and clinical history of type 2 diabetes - mechanisms and potentials for treatment
    • Giaccari A., Sorice G., Muscogiuri G. Glucose toxicity: the leading actor in the pathogenesis and clinical history of type 2 diabetes - mechanisms and potentials for treatment. Nutr Metab Cardiovasc Dis 2009 Jun, 19(5):365-377. 10.1016/j.numecd.2009.03.018.
    • (2009) Nutr Metab Cardiovasc Dis , vol.19 , Issue.5 , pp. 365-377
    • Giaccari, A.1    Sorice, G.2    Muscogiuri, G.3
  • 3
    • 25644444543 scopus 로고    scopus 로고
    • Diabetes mellitus is associated with an increased risk of falls in elderly residents of a long-term care facility
    • Maurer M.S., Burcham J., Cheng H. Diabetes mellitus is associated with an increased risk of falls in elderly residents of a long-term care facility. J Gerontol A Biol Sci Med Sci 2005, 60:1157-1162.
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 1157-1162
    • Maurer, M.S.1    Burcham, J.2    Cheng, H.3
  • 4
    • 22244463889 scopus 로고    scopus 로고
    • Increased incidence of vertebral fracture in older female hemodialyzed patients with type 2 diabetes mellitus
    • Inaba M., Okuno S., Kumeda Y., Yamakawa T., Ishimura E., Nishizawa Y. Increased incidence of vertebral fracture in older female hemodialyzed patients with type 2 diabetes mellitus. Calcif Tissue Int 2005, 76:256-260. 10.1007/s00223-004-0094-0.
    • (2005) Calcif Tissue Int , vol.76 , pp. 256-260
    • Inaba, M.1    Okuno, S.2    Kumeda, Y.3    Yamakawa, T.4    Ishimura, E.5    Nishizawa, Y.6
  • 5
    • 0032920820 scopus 로고    scopus 로고
    • Impact of peripheral neuropathy on bone density in patients with type 1 diabetes
    • Rix M., Andreassen H., Eskildsen P. Impact of peripheral neuropathy on bone density in patients with type 1 diabetes. Diabetes Care 1999, 22:827-831. 10.2337/diacare.22.5.827.
    • (1999) Diabetes Care , vol.22 , pp. 827-831
    • Rix, M.1    Andreassen, H.2    Eskildsen, P.3
  • 6
    • 0031024406 scopus 로고    scopus 로고
    • Bone mineral density and blood flow to the lower extremities: the study of osteoporotic fractures
    • Vogt M.T., Cauley J.A., Kuller L.H., Nevitt M.C. Bone mineral density and blood flow to the lower extremities: the study of osteoporotic fractures. J Bone Miner Res 1997, 12:283-289. 10.1359/jbmr.1997.12.2.283.
    • (1997) J Bone Miner Res , vol.12 , pp. 283-289
    • Vogt, M.T.1    Cauley, J.A.2    Kuller, L.H.3    Nevitt, M.C.4
  • 7
  • 8
    • 36849045166 scopus 로고    scopus 로고
    • Understanding the pathology and mechanisms of type I diabetic bone loss
    • McCabe L.R. Understanding the pathology and mechanisms of type I diabetic bone loss. J Cell Biochem 2007, 102:1343-1357. 10.1002/jcb.21573.
    • (2007) J Cell Biochem , vol.102 , pp. 1343-1357
    • McCabe, L.R.1
  • 9
    • 0031847191 scopus 로고    scopus 로고
    • Decreased lumbar spine bone mass and low bone turnover in children and adolescents with insulin dependent diabetes mellitus followed longitudinally
    • Gunczler P., Lanes R., Paz-Martinez V., Martins R., Esaa S., Colmenares V., et al. Decreased lumbar spine bone mass and low bone turnover in children and adolescents with insulin dependent diabetes mellitus followed longitudinally. J Pediatr Endocrinol Metab 1998, 11:413-419.
    • (1998) J Pediatr Endocrinol Metab , vol.11 , pp. 413-419
    • Gunczler, P.1    Lanes, R.2    Paz-Martinez, V.3    Martins, R.4    Esaa, S.5    Colmenares, V.6
  • 10
    • 0031985186 scopus 로고    scopus 로고
    • Bone mineral density in children and adolescents with diabetes mellitus type 1 of recent onset
    • Pascual J., Argente J., Lopez M.B., Munoz M., Martinez G., Vazquez M.A., et al. Bone mineral density in children and adolescents with diabetes mellitus type 1 of recent onset. Calcif Tissue Int 1998, 62:31-35. 10.1007/s002239900390.
    • (1998) Calcif Tissue Int , vol.62 , pp. 31-35
    • Pascual, J.1    Argente, J.2    Lopez, M.B.3    Munoz, M.4    Martinez, G.5    Vazquez, M.A.6
  • 11
    • 0036438958 scopus 로고    scopus 로고
    • The lumbar bone mineral density is affected by long-term poor metabolic control in adolescents with type 1 diabetes mellitus
    • Valerio G., del Puente A., Esposito-del Puente A., Buono P., Mozzillo E., Francese A. The lumbar bone mineral density is affected by long-term poor metabolic control in adolescents with type 1 diabetes mellitus. Horm Res 2002, 58:266-272. 10.1159/000066441.
    • (2002) Horm Res , vol.58 , pp. 266-272
    • Valerio, G.1    del Puente, A.2    Esposito-del Puente, A.3    Buono, P.4    Mozzillo, E.5    Francese, A.6
  • 12
    • 56749165325 scopus 로고    scopus 로고
    • IGF-1 and IGF-binding proteins and bone mass, geometry and strength: relation to metabolic control in adolescent girls with type 1 diabetes
    • Moyer-Mileur L.J., Slater H., Jordan K.C., Murray M.A. IGF-1 and IGF-binding proteins and bone mass, geometry and strength: relation to metabolic control in adolescent girls with type 1 diabetes. J Bone Miner Res 2008, 23:1884-1891.
    • (2008) J Bone Miner Res , vol.23 , pp. 1884-1891
    • Moyer-Mileur, L.J.1    Slater, H.2    Jordan, K.C.3    Murray, M.A.4
  • 14
    • 33646377660 scopus 로고    scopus 로고
    • Middle-aged premenopausal women with type 1 diabetes have lower bone mineral density and calcaneal quantitative ultrasound than nondiabetic women
    • Strotmeyer E.S., Cauley J.A., Orchard T.J., Steenkiste A.R., Dorman J.S. Middle-aged premenopausal women with type 1 diabetes have lower bone mineral density and calcaneal quantitative ultrasound than nondiabetic women. Diabetes Care 2006, 29:306-311.
    • (2006) Diabetes Care , vol.29 , pp. 306-311
    • Strotmeyer, E.S.1    Cauley, J.A.2    Orchard, T.J.3    Steenkiste, A.R.4    Dorman, J.S.5
  • 15
    • 0031468741 scopus 로고    scopus 로고
    • Microalbuminuria as an early indicator of osteopenia in male insulin dependent diabetic patients
    • Clausen P., Feldt-Rasmussen B., Jacobsen P., Rossing K., Parving H.H., Nielsen P.K., et al. Microalbuminuria as an early indicator of osteopenia in male insulin dependent diabetic patients. Diabet Med 1997, 14:1038-1043.
    • (1997) Diabet Med , vol.14 , pp. 1038-1043
    • Clausen, P.1    Feldt-Rasmussen, B.2    Jacobsen, P.3    Rossing, K.4    Parving, H.H.5    Nielsen, P.K.6
  • 16
    • 33644828429 scopus 로고    scopus 로고
    • Elevated hip fracture risk in type 1 diabetic patients: a population-based cohort study in sweden
    • Miao J., Brismar K., Nyren O., Ugarph-Morawski A., Ye W. Elevated hip fracture risk in type 1 diabetic patients: a population-based cohort study in sweden. Diabetes Care 2005, 28:2850-2855.
    • (2005) Diabetes Care , vol.28 , pp. 2850-2855
    • Miao, J.1    Brismar, K.2    Nyren, O.3    Ugarph-Morawski, A.4    Ye, W.5
  • 17
    • 84905094655 scopus 로고    scopus 로고
    • Impact of diabetes and its treatment on bone
    • Schwartz A.V. Impact of diabetes and its treatment on bone. Clin Rev Bone Miner Metab 2009, 7:249-260.
    • (2009) Clin Rev Bone Miner Metab , vol.7 , pp. 249-260
    • Schwartz, A.V.1
  • 18
    • 8344248424 scopus 로고    scopus 로고
    • Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: the health, aging, and body composition study
    • Strotmeyer E.S., Cauley J.A., Schwartz A.V., Nevitt M.C., Resnick H.E., Zmuda J.M., et al. Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: the health, aging, and body composition study. J Bone Miner Res 2004, 19:1084-1091.
    • (2004) J Bone Miner Res , vol.19 , pp. 1084-1091
    • Strotmeyer, E.S.1    Cauley, J.A.2    Schwartz, A.V.3    Nevitt, M.C.4    Resnick, H.E.5    Zmuda, J.M.6
  • 20
    • 34248587763 scopus 로고    scopus 로고
    • Biphasic fracture risk in diabetes: a population-based study
    • Leslie W.D., Lix L.M., Prior H.J., Derksen S., Metge C., O'Neil J. Biphasic fracture risk in diabetes: a population-based study. Bone 2007, 40:1595-1601. 10.1016/j.bone.2007.02.021.
    • (2007) Bone , vol.40 , pp. 1595-1601
    • Leslie, W.D.1    Lix, L.M.2    Prior, H.J.3    Derksen, S.4    Metge, C.5    O'Neil, J.6
  • 23
    • 77953401724 scopus 로고    scopus 로고
    • Bone mass and strength in older men with type II diabetes: the osteoporotic fractures in men study
    • Petit M., Paudel M.L., Taylor B., Hughes J., Strotmeyer E.S., Schwartz A.V., et al. Bone mass and strength in older men with type II diabetes: the osteoporotic fractures in men study. J Bone Miner Res 2010, 25:285-291.
    • (2010) J Bone Miner Res , vol.25 , pp. 285-291
    • Petit, M.1    Paudel, M.L.2    Taylor, B.3    Hughes, J.4    Strotmeyer, E.S.5    Schwartz, A.V.6
  • 24
    • 77953520506 scopus 로고    scopus 로고
    • Age and gender related differences in the geometric properties and biomechanical significance of intra-cortical porosity in the distal radius and tibia
    • Burghardt A.J., Kazakia G.J., Ramachandran S., Link T.M., Majumdar S. Age and gender related differences in the geometric properties and biomechanical significance of intra-cortical porosity in the distal radius and tibia. J Bone Miner Res 2010, 25:983-993.
    • (2010) J Bone Miner Res , vol.25 , pp. 983-993
    • Burghardt, A.J.1    Kazakia, G.J.2    Ramachandran, S.3    Link, T.M.4    Majumdar, S.5
  • 26
    • 76549123888 scopus 로고    scopus 로고
    • Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus
    • Saito M., Marumo K. Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int 2010, 21:195-214.
    • (2010) Osteoporos Int , vol.21 , pp. 195-214
    • Saito, M.1    Marumo, K.2
  • 27
    • 42049118293 scopus 로고    scopus 로고
    • Clinical review: the role of advanced glycation end products in progression and complications of diabetes
    • Goh S.Y., Cooper M.E. Clinical review: the role of advanced glycation end products in progression and complications of diabetes. J Clin Endocrinol Metab 2008, 93:1143-1152.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1143-1152
    • Goh, S.Y.1    Cooper, M.E.2
  • 28
    • 57549088847 scopus 로고    scopus 로고
    • Simple and sensitive method for quantification of fluorescent enzymatic mature and senescent crosslinks of collagen in bone hydrolysate using single column high performance liquid chromatography
    • Viguet-Carrin S., Gineyts E., Bertholon C. Simple and sensitive method for quantification of fluorescent enzymatic mature and senescent crosslinks of collagen in bone hydrolysate using single column high performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2009, 877:1-7. 10.1016/j.jchromb.2008.10.043.
    • (2009) J Chromatogr B Analyt Technol Biomed Life Sci , vol.877 , pp. 1-7
    • Viguet-Carrin, S.1    Gineyts, E.2    Bertholon, C.3
  • 29
    • 33749518488 scopus 로고    scopus 로고
    • Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae
    • Viguet-Carrin S., Roux J.P., Arlot M.E., Merabet Z., Leeming D.J., Byrjalsen I., et al. Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 2006, 39:1073-1079. 10.1016/j.bone.2006.05.013.
    • (2006) Bone , vol.39 , pp. 1073-1079
    • Viguet-Carrin, S.1    Roux, J.P.2    Arlot, M.E.3    Merabet, Z.4    Leeming, D.J.5    Byrjalsen, I.6
  • 30
    • 0035134299 scopus 로고    scopus 로고
    • Influence of nonenzymatic glycation on biomechanical properties of cortical bone
    • Vashishth D., Gibson G.J., Khoury J.I., Schaffler M.B., Kimura J., Fyhrie D.P. Influence of nonenzymatic glycation on biomechanical properties of cortical bone. Bone 2001, 28:195-201. 10.1016/S8756-3282(00)00434-8.
    • (2001) Bone , vol.28 , pp. 195-201
    • Vashishth, D.1    Gibson, G.J.2    Khoury, J.I.3    Schaffler, M.B.4    Kimura, J.5    Fyhrie, D.P.6
  • 32
    • 40849130165 scopus 로고    scopus 로고
    • Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes
    • Yamamoto M., Yamaguchi T., Yamauchi M., Kaji H., Sugimoto T. Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab 2008, 93:1013-1019.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1013-1019
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Kaji, H.4    Sugimoto, T.5
  • 34
    • 72249109142 scopus 로고    scopus 로고
    • Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes
    • Yamamoto M., Yamaguchi T., Yamauchi M., Sugimoto T. Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes. Diabetes Care 2009, 32:2263-2268.
    • (2009) Diabetes Care , vol.32 , pp. 2263-2268
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Sugimoto, T.4
  • 35
    • 0030942092 scopus 로고    scopus 로고
    • Effects of advanced glycation endproducts on the proliferation and differentiation of osteoblast-like cells
    • McCarthy A.D., Etcheverry S.B., Bruzzone L., Cortizo A.M. Effects of advanced glycation endproducts on the proliferation and differentiation of osteoblast-like cells. Mol Cell Biochem 1997, 170:43-51.
    • (1997) Mol Cell Biochem , vol.170 , pp. 43-51
    • McCarthy, A.D.1    Etcheverry, S.B.2    Bruzzone, L.3    Cortizo, A.M.4
  • 38
    • 0029941668 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid
    • Conover C.A., Lee P.D., Riggs B.L., Powell D.R. Insulin-like growth factor-binding protein-1 expression in cultured human bone cells: regulation by insulin and glucocorticoid. Endocrinology 1996, 137:3295-3301.
    • (1996) Endocrinology , vol.137 , pp. 3295-3301
    • Conover, C.A.1    Lee, P.D.2    Riggs, B.L.3    Powell, D.R.4
  • 39
    • 17144438059 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover
    • Ogata N., Chikazu D., Kubota N., Terauchi Y., Tobe K., Azuma Y., et al. Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. J Clin Invest 2000, 105:935-943.
    • (2000) J Clin Invest , vol.105 , pp. 935-943
    • Ogata, N.1    Chikazu, D.2    Kubota, N.3    Terauchi, Y.4    Tobe, K.5    Azuma, Y.6
  • 40
    • 33751523583 scopus 로고    scopus 로고
    • Normal bone density obtained in the absence of insulin receptor expression in bone
    • Irwin R., Lin H.V., Motyl K.J., McCabe L.R. Normal bone density obtained in the absence of insulin receptor expression in bone. Endocrinology 2006, 147:5760-5767.
    • (2006) Endocrinology , vol.147 , pp. 5760-5767
    • Irwin, R.1    Lin, H.V.2    Motyl, K.J.3    McCabe, L.R.4
  • 41
    • 0033028690 scopus 로고    scopus 로고
    • The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and diabetic mice, but is regulated through the insulin-like growth factor I receptor
    • Maor G., Karnieli E. The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and diabetic mice, but is regulated through the insulin-like growth factor I receptor. Endocrinology 1999, 140:1841-1851.
    • (1999) Endocrinology , vol.140 , pp. 1841-1851
    • Maor, G.1    Karnieli, E.2
  • 42
    • 49549111375 scopus 로고    scopus 로고
    • Growth hormone, insulin-like growth factors, and the skeleton
    • Giustina A., Mazziotti G., Canalis E. Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev 2008, 29:535-559.
    • (2008) Endocr Rev , vol.29 , pp. 535-559
    • Giustina, A.1    Mazziotti, G.2    Canalis, E.3
  • 43
    • 0032899253 scopus 로고    scopus 로고
    • Alterations in the growth hormone-insulin-like growth factor axis in insulin dependent diabetes mellitus
    • Bereket A., Lang C.H., Wilson T.A. Alterations in the growth hormone-insulin-like growth factor axis in insulin dependent diabetes mellitus. Horm Metab Res 1999, 31:172-181.
    • (1999) Horm Metab Res , vol.31 , pp. 172-181
    • Bereket, A.1    Lang, C.H.2    Wilson, T.A.3
  • 44
    • 0034891376 scopus 로고    scopus 로고
    • The role of IGFbinding proteins in mediating the effects of recombinant human IGF-I on insulin requirements in type 1 diabetes mellitus
    • Crowne E.C., Samra J.S., Cheetham T., Acerini C.L., Watts A., Holly J.M., et al. The role of IGFbinding proteins in mediating the effects of recombinant human IGF-I on insulin requirements in type 1 diabetes mellitus. J Clin Endocrinol Metab 2001, 86:3686-3691.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3686-3691
    • Crowne, E.C.1    Samra, J.S.2    Cheetham, T.3    Acerini, C.L.4    Watts, A.5    Holly, J.M.6
  • 45
    • 43149117061 scopus 로고    scopus 로고
    • Relationships between fat and bone
    • Reid I.R. Relationships between fat and bone. Osteoporos Int 2008, 19:595-606.
    • (2008) Osteoporos Int , vol.19 , pp. 595-606
    • Reid, I.R.1
  • 46
    • 0031028449 scopus 로고    scopus 로고
    • Vitamin D, glucose tolerance and insulinaemia in elderly men
    • Baynes K.C., Boucher B.J., Feskens E.J., Kromhout D. Vitamin D, glucose tolerance and insulinaemia in elderly men. Diabetologia 1997, 40:344-347.
    • (1997) Diabetologia , vol.40 , pp. 344-347
    • Baynes, K.C.1    Boucher, B.J.2    Feskens, E.J.3    Kromhout, D.4
  • 47
    • 0036096735 scopus 로고    scopus 로고
    • Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin- D3
    • Gysemans C., Van Etten E., Overbergh L., Verstuyf A., Waer M., Bouillon R., et al. Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin- D3. Clin Exp Immunol 2002, 128:213-220.
    • (2002) Clin Exp Immunol , vol.128 , pp. 213-220
    • Gysemans, C.1    Van Etten, E.2    Overbergh, L.3    Verstuyf, A.4    Waer, M.5    Bouillon, R.6
  • 49
    • 44449087465 scopus 로고    scopus 로고
    • Leptin and the sympathetic connection of fat to bone
    • Hamrick M.W., Ferrari S.L. Leptin and the sympathetic connection of fat to bone. Osteoporos Int 2008, 19:905-912.
    • (2008) Osteoporos Int , vol.19 , pp. 905-912
    • Hamrick, M.W.1    Ferrari, S.L.2
  • 50
    • 61449206180 scopus 로고    scopus 로고
    • Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and vertebral fractures in type 2 diabetes mellitus
    • Kanazawa I., Yamaguchi T., Yamamoto M., Yamauchi M., Yano S., Sugimoto T. Relationships between serum adiponectin levels versus bone mineral density, bone metabolic markers, and vertebral fractures in type 2 diabetes mellitus. Eur J Endocrinol 2009, 160:265-273.
    • (2009) Eur J Endocrinol , vol.160 , pp. 265-273
    • Kanazawa, I.1    Yamaguchi, T.2    Yamamoto, M.3    Yamauchi, M.4    Yano, S.5    Sugimoto, T.6
  • 51
    • 0030982442 scopus 로고    scopus 로고
    • Metabolic improvement of poorly controlled noninsulin-dependent diabetes mellitus decreases bone turnover
    • Okazaki R., Totsuka Y., Hamano K., Ajima M., Miura M., Hirota Y., et al. Metabolic improvement of poorly controlled noninsulin-dependent diabetes mellitus decreases bone turnover. J Clin Endocrinol Metab 1997, 82:2915-2920.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2915-2920
    • Okazaki, R.1    Totsuka, Y.2    Hamano, K.3    Ajima, M.4    Miura, M.5    Hirota, Y.6
  • 52
    • 35648929883 scopus 로고    scopus 로고
    • Gone with the Wnts: β-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism
    • Manolagas S.C., Almeida M. Gone with the Wnts: β-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism. Mol Endocrinol 2007, 21:2605-2614.
    • (2007) Mol Endocrinol , vol.21 , pp. 2605-2614
    • Manolagas, S.C.1    Almeida, M.2
  • 53
    • 34147176168 scopus 로고    scopus 로고
    • The risk of hip fractures in older individuals with diabetes: a population based study
    • Lipscombe L.L., Jamal S.A., Booth G.L., Hawker G.A. The risk of hip fractures in older individuals with diabetes: a population based study. Diabetes Care 2007, 30:835-841.
    • (2007) Diabetes Care , vol.30 , pp. 835-841
    • Lipscombe, L.L.1    Jamal, S.A.2    Booth, G.L.3    Hawker, G.A.4
  • 56
    • 53149104764 scopus 로고    scopus 로고
    • TZDs and bone: a review of the recent clinical evidence
    • Schwartz A.V. TZDs and bone: a review of the recent clinical evidence. PPAR Res 2008, 2008:297893.
    • (2008) PPAR Res , vol.2008 , pp. 297893
    • Schwartz, A.V.1
  • 57
    • 58849094131 scopus 로고    scopus 로고
    • Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis
    • Loke Y.K., Singh S., Furberg C.D. Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis. Can Med Assoc J 2009, 180:32-39.
    • (2009) Can Med Assoc J , vol.180 , pp. 32-39
    • Loke, Y.K.1    Singh, S.2    Furberg, C.D.3
  • 58
    • 48649095960 scopus 로고    scopus 로고
    • Rosiglitazone associated fractures in type 2 diabetes: an analysis from A Diabetes Outcome Progression Trial (ADOPT)
    • Kahn S.E., Zinman B., Lachin J.M., Haffner S.M., Herman W.H., Holman R.R., et al. Rosiglitazone associated fractures in type 2 diabetes: an analysis from A Diabetes Outcome Progression Trial (ADOPT). Diabetes Care 2008, 31:845-851.
    • (2008) Diabetes Care , vol.31 , pp. 845-851
    • Kahn, S.E.1    Zinman, B.2    Lachin, J.M.3    Haffner, S.M.4    Herman, W.H.5    Holman, R.R.6
  • 59
    • 76149114236 scopus 로고    scopus 로고
    • Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus
    • [published ahead of print]
    • Habib Z.A., Havstad S.L., Wells K., Divine G., Pladevall M., Williams L.K. Thiazolidinedione use and the longitudinal risk of fractures in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 2010, 95:592-600. [published ahead of print]. 10.1210/jc.2009-1385.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 592-600
    • Habib, Z.A.1    Havstad, S.L.2    Wells, K.3    Divine, G.4    Pladevall, M.5    Williams, L.K.6
  • 60
    • 23944490347 scopus 로고    scopus 로고
    • Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk
    • Vestergaard P., Rejnmark L., Mosekilde L. Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk. Diabetologia 2005, 48:1292-1299.
    • (2005) Diabetologia , vol.48 , pp. 1292-1299
    • Vestergaard, P.1    Rejnmark, L.2    Mosekilde, L.3
  • 61
    • 75149119236 scopus 로고    scopus 로고
    • Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes
    • ADOPT Study Group
    • Zinman B., Haffner S.M., Herman W.H., Holman R.R., Lachin J.M., Kravitz B.G., et al. Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes. J Clin Endocrinol Metab 2010, 95:134-142. ADOPT Study Group.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 134-142
    • Zinman, B.1    Haffner, S.M.2    Herman, W.H.3    Holman, R.R.4    Lachin, J.M.5    Kravitz, B.G.6
  • 62
    • 33645851342 scopus 로고    scopus 로고
    • Osteogenic actions of the anti-diabetic drug metformin on osteoblasts in culture
    • Cortizo A.M., Sedlinsky C., McCarthy A.D., Blanco A., Schurman L. Osteogenic actions of the anti-diabetic drug metformin on osteoblasts in culture. Eur J Phamacol 2006, 536:38-46. 10.1016/j.ejphar.2006.02.030.
    • (2006) Eur J Phamacol , vol.536 , pp. 38-46
    • Cortizo, A.M.1    Sedlinsky, C.2    McCarthy, A.D.3    Blanco, A.4    Schurman, L.5
  • 63
    • 76249088270 scopus 로고    scopus 로고
    • Glimepiride induces proliferation and differentiation of rat osteoblasts via the PI3-kinase/Akt pathway
    • Ma P., Gu B., Ma J., E L., Wu X., Cao J., et al. Glimepiride induces proliferation and differentiation of rat osteoblasts via the PI3-kinase/Akt pathway. Metabolism 2010 Mar, 59(3):359-366. 10.1016/j.metabol.2009.08.003.
    • (2010) Metabolism , vol.59 , Issue.3 , pp. 359-366
    • Ma, P.1    Gu, B.2    Ma, J.3    E, L.4    Wu, X.5    Cao, J.6
  • 64
    • 70350513013 scopus 로고    scopus 로고
    • Efficacy and safety of incretin based therapies: clinical trial data
    • White J. Efficacy and safety of incretin based therapies: clinical trial data. J Am Pharm Assoc 2009, 49:S30-S40.
    • (2009) J Am Pharm Assoc , vol.49
    • White, J.1
  • 65
    • 77950880269 scopus 로고    scopus 로고
    • Dipeptydil peptidase-4 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials
    • Monami M., Iacomelli I., Marchionni N., Mannucci E. Dipeptydil peptidase-4 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis 2010, 20:224-235. 10.1016/j.numecd.2009.03.015.
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , pp. 224-235
    • Monami, M.1    Iacomelli, I.2    Marchionni, N.3    Mannucci, E.4
  • 66
    • 24144465674 scopus 로고    scopus 로고
    • Potential role of pancreatic and enteric hormones in regulating bone turnover
    • Clowes J.A., Khosla S., Eastell R. Potential role of pancreatic and enteric hormones in regulating bone turnover. J Bone Miner Res 2005, 20:1497-1506.
    • (2005) J Bone Miner Res , vol.20 , pp. 1497-1506
    • Clowes, J.A.1    Khosla, S.2    Eastell, R.3
  • 67
    • 38549146030 scopus 로고    scopus 로고
    • The murine glucagon like peptide-1 receptor is essential for control of bone resorption
    • Yamada C., Yamada Y., Tsukiyama K., Yamada K., Udagawa N., Takahashi N., et al. The murine glucagon like peptide-1 receptor is essential for control of bone resorption. Endocrinology 2008, 149:574-579.
    • (2008) Endocrinology , vol.149 , pp. 574-579
    • Yamada, C.1    Yamada, Y.2    Tsukiyama, K.3    Yamada, K.4    Udagawa, N.5    Takahashi, N.6
  • 68
    • 34547690686 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism by the skeleton
    • Lee N.K., Sowa H., Hinoi E., Ferron M., Ahn J.D., Confavreux C., et al. Endocrine regulation of energy metabolism by the skeleton. Cell 2007, 130:456-469.
    • (2007) Cell , vol.130 , pp. 456-469
    • Lee, N.K.1    Sowa, H.2    Hinoi, E.3    Ferron, M.4    Ahn, J.D.5    Confavreux, C.6
  • 69
    • 42449096306 scopus 로고    scopus 로고
    • Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
    • Ferron M., Hinoi E., Karsenty G., Ducy P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci USA 2008, 105:5266-5270.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5266-5270
    • Ferron, M.1    Hinoi, E.2    Karsenty, G.3    Ducy, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.