-
1
-
-
0027946689
-
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
-
Katagiri T., Yamaguchi A., Komaki M., Abe E., Takahashi N., Ikeda T., Rosen V., Wozney J.M., Fujisawa-Sehara A., Suda T. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J. Cell. Biol. 127:1994;1755-1766.
-
(1994)
J. Cell. Biol.
, vol.127
, pp. 1755-1766
-
-
Katagiri, T.1
Yamaguchi, A.2
Komaki, M.3
Abe, E.4
Takahashi, N.5
Ikeda, T.6
Rosen, V.7
Wozney, J.M.8
Fujisawa-Sehara, A.9
Suda, T.10
-
2
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin C.H., Miyazono K., ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature. 390:1997;465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
3
-
-
0030826702
-
A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts
-
Namiki M., Akiyama S., Katagiri T., Suzuki A., Ueno N., Yamaji N., Rosen V., Wozney J.M., Suda T. A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts. J. Biol. Chem. 272:1997;22046-22052.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22046-22052
-
-
Namiki, M.1
Akiyama, S.2
Katagiri, T.3
Suzuki, A.4
Ueno, N.5
Yamaji, N.6
Rosen, V.7
Wozney, J.M.8
Suda, T.9
-
4
-
-
0031572322
-
Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts
-
Akiyama S., Katagiri T., Namiki M., Yamaji N., Yamamoto N., Miyama K., Shibuya H., Ueno N., Wozney J.M., Suda T. Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts. Exp. Cell. Res. 235:1997;362-369.
-
(1997)
Exp. Cell. Res.
, vol.235
, pp. 362-369
-
-
Akiyama, S.1
Katagiri, T.2
Namiki, M.3
Yamaji, N.4
Yamamoto, N.5
Miyama, K.6
Shibuya, H.7
Ueno, N.8
Wozney, J.M.9
Suda, T.10
-
5
-
-
0031577571
-
Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts
-
Yamamoto N., Akiyama S., Katagiri T., Namiki M., Kurokawa T., Suda T. Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts. Biochem. Biophys. Res. Commun. 238:1997;574-580.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.238
, pp. 574-580
-
-
Yamamoto, N.1
Akiyama, S.2
Katagiri, T.3
Namiki, M.4
Kurokawa, T.5
Suda, T.6
-
6
-
-
0031939744
-
Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12
-
Nishimura R., Kato Y., Chen D., Harris S.E., Mundy G.R., Yoneda T. Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. J. Biol. Chem. 273:1998;1872-1879.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1872-1879
-
-
Nishimura, R.1
Kato, Y.2
Chen, D.3
Harris, S.E.4
Mundy, G.R.5
Yoneda, T.6
-
7
-
-
0033120184
-
A BMP-inducible gene, Dlx5, regulates osteoblast differentiation and mesoderm induction
-
Miyama K., Yamada G., Yamamoto T.S., Takagi C., Miyado K., Sakai M., Ueno N., Shibuya H. A BMP-inducible gene, Dlx5, regulates osteoblast differentiation and mesoderm induction. Dev. Biol. 208:1999;123-133.
-
(1999)
Dev. Biol.
, vol.208
, pp. 123-133
-
-
Miyama, K.1
Yamada, G.2
Yamamoto, T.S.3
Takagi, C.4
Miyado, K.5
Sakai, M.6
Ueno, N.7
Shibuya, H.8
-
8
-
-
0034913235
-
Differential regulation of Dlx gene expression by a BMP morphogenetic gradient
-
Luo T., Matsuo-Takasaki M., Lim J.H., Sargent T.D. Differential regulation of Dlx gene expression by a BMP morphogenetic gradient. Int. J. Dev. Biol. 45:2001;681-684. M.H. Lee, Y.J. Kim, H.J. Kim, H.D. Park, A.R. Kang, H.M. Kyung, J.H. Sung, J.M. Wozney, H.J. Kim, H.M. Ryoo, BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-β1 opposes the BMP-2-induced osteoblast differentiation by suppression of the Dlx5 expression, J. Biol. Chem. 278 (2003) (in press).
-
(2001)
Int. J. Dev. Biol.
, vol.45
, pp. 681-684
-
-
Luo, T.1
Matsuo-Takasaki, M.2
Lim, J.H.3
Sargent, T.D.4
-
9
-
-
0042891942
-
BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-β1 opposes the BMP-2-induced osteoblast differentiation by suppression of the Dlx5 expression
-
in press
-
M.H. Lee, Y.J. Kim, H.J. Kim, H.D. Park, A.R. Kang, H.M. Kyung, J.H. Sung, J.M. Wozney, H.J. Kim, H.M. Ryoo, BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-β1 opposes the BMP-2-induced osteoblast differentiation by suppression of the Dlx5 expression, J. Biol. Chem. 278 (2003) (in press).
-
(2003)
J. Biol. Chem.
, vol.278
-
-
Lee, M.H.1
Kim, Y.J.2
Kim, H.J.3
Park, H.D.4
Kang, A.R.5
Kyung, H.M.6
Sung, J.H.7
Wozney, J.M.8
Kim, H.J.9
Ryoo, H.M.10
-
10
-
-
0033120916
-
Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation
-
Lee M.H., Javed A., Kim H.J., Shin H.I., Gutierrez S., Choi J.Y., Rosen V., Stein J.L., van Wijnen A.J., Stein G.S., Lian J.B., Ryoo H.M. Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation. J. Cell. Biochem. 73:1999;114-125.
-
(1999)
J. Cell. Biochem.
, vol.73
, pp. 114-125
-
-
Lee, M.H.1
Javed, A.2
Kim, H.J.3
Shin, H.I.4
Gutierrez, S.5
Choi, J.Y.6
Rosen, V.7
Stein, J.L.8
Van Wijnen, A.J.9
Stein, G.S.10
Lian, J.B.11
Ryoo, H.M.12
-
11
-
-
0034460993
-
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12
-
Lee K.S., Kim H.J., Li Q.L., Chi X.Z., Ueta C., Komori T., Wozney J.M., Kim E.G., Choi J.Y., Ryoo H.M., Bae S.C. Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol. Cell. Biol. 20:2000;8783-8792.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8783-8792
-
-
Lee, K.S.1
Kim, H.J.2
Li, Q.L.3
Chi, X.Z.4
Ueta, C.5
Komori, T.6
Wozney, J.M.7
Kim, E.G.8
Choi, J.Y.9
Ryoo, H.M.10
Bae, S.C.11
-
12
-
-
0037059614
-
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
-
Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., de Crombrugghe B. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 108:2002;17-29.
-
(2002)
Cell
, vol.108
, pp. 17-29
-
-
Nakashima, K.1
Zhou, X.2
Kunkel, G.3
Zhang, Z.4
Deng, J.M.5
Behringer, R.R.6
De Crombrugghe, B.7
-
13
-
-
0030801264
-
Stage-specific expression of Dlx-5 during osteoblast differentiation: Involvement in regulation of osteocalcin gene expression
-
Ryoo H.M., Hoffmann H.M., Beumer T., Frenkel B., Towler D.A., Stein G.S., Stein J.L., van Wijnen A.J., Lian J.B. Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Mol. Endocrinol. 11:1997;1681-1694.
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 1681-1694
-
-
Ryoo, H.M.1
Hoffmann, H.M.2
Beumer, T.3
Frenkel, B.4
Towler, D.A.5
Stein, G.S.6
Stein, J.L.7
Van Wijnen, A.J.8
Lian, J.B.9
-
14
-
-
0034766416
-
Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Masx and Dlx5
-
Shirakabe K., Terasawa K., Miyama K., Shibuya H., Nishida E. Regulation of the activity of the transcription factor Runx2 by two homeobox proteins, Masx and Dlx5. Genes Cells. 6:2001;851-856.
-
(2001)
Genes Cells
, vol.6
, pp. 851-856
-
-
Shirakabe, K.1
Terasawa, K.2
Miyama, K.3
Shibuya, H.4
Nishida, E.5
-
15
-
-
0035999434
-
Overexpression of Dlx5 in chicken calvarial cells accelerates osteoblastic differentiation
-
Tadic T., Dodig M., Erceg I., Marijanovic I., Mina M., Kalajzic Z., Velonis D., Kronenberg M.S., Kosher R.A., Ferrari D., Lichtler A.C. Overexpression of Dlx5 in chicken calvarial cells accelerates osteoblastic differentiation. J. Bone Miner. Res. 17:2002;1008-1014.
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 1008-1014
-
-
Tadic, T.1
Dodig, M.2
Erceg, I.3
Marijanovic, I.4
Mina, M.5
Kalajzic, Z.6
Velonis, D.7
Kronenberg, M.S.8
Kosher, R.A.9
Ferrari, D.10
Lichtler, A.C.11
-
16
-
-
0032872336
-
Craniofacial, vestibular and bone defects in mice lacking the distal-less-related gene Dlx5
-
Acampora D., Merlo G.R., Paleari L., Zerega B., Postiglione M.P., Mantero S., Bober E., Barbieri O., Simeone A., Levi G. Craniofacial, vestibular and bone defects in mice lacking the distal-less-related gene Dlx5. Development. 126:1999;3795-3809.
-
(1999)
Development
, vol.126
, pp. 3795-3809
-
-
Acampora, D.1
Merlo, G.R.2
Paleari, L.3
Zerega, B.4
Postiglione, M.P.5
Mantero, S.6
Bober, E.7
Barbieri, O.8
Simeone, A.9
Levi, G.10
-
17
-
-
0036558218
-
The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
-
Robledo R.F., Rajan L., Li X., Lufkin T. The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 16:2002;1089-1101.
-
(2002)
Genes Dev.
, vol.16
, pp. 1089-1101
-
-
Robledo, R.F.1
Rajan, L.2
Li, X.3
Lufkin, T.4
-
18
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy P., Zhang R., Geoffroy V., Ridall A.L., Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89:1997;747-754.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
19
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T., Yagi H., Nomura S., Yamaguchi A., Sasaki K., Deguchi K., Shimizu Y., Bronson R.T., Gao Y.H., Inada M., Sato M., Okamoto R., Kitamura Y., Yoshiki S., Kishimoto T. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 89:1997;755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
20
-
-
0034641617
-
A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia
-
Zhang Y.W., Yasui N., Ito K., Huang G., Fujii M., Hanai J., Nogami H., Ochi T., Miyazono K., Ito Y. A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia. Proc. Natl. Acad. Sci. USA. 97:2000;10549-10554.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10549-10554
-
-
Zhang, Y.W.1
Yasui, N.2
Ito, K.3
Huang, G.4
Fujii, M.5
Hanai, J.6
Nogami, H.7
Ochi, T.8
Miyazono, K.9
Ito, Y.10
-
21
-
-
0032323828
-
Advances in the osteoblast lineage
-
Aubin J.E. Advances in the osteoblast lineage. Biochem. Cell Biol. 76:1998;899-910.
-
(1998)
Biochem. Cell Biol.
, vol.76
, pp. 899-910
-
-
Aubin, J.E.1
-
22
-
-
0030690556
-
The missing bone
-
Rodan G.A., Harada S. The missing bone. Cell. 89:1997;677-680.
-
(1997)
Cell
, vol.89
, pp. 677-680
-
-
Rodan, G.A.1
Harada, S.2
-
23
-
-
34250019537
-
Bone: Formation by autoinduction
-
Urist M.R. Bone: formation by autoinduction. Science. 150:1965;893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
24
-
-
0024256133
-
Novel regulators of bone formation: Molecular clones and activities
-
Wozney J.M., Rosen V., Celeste A.J., Mitsock L.M., Whitters M.J., Kriz R.W., Hewick R.M., Wang E.A. Novel regulators of bone formation: molecular clones and activities. Science. 242:1988;1528-1534.
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.W.6
Hewick, R.M.7
Wang, E.A.8
-
25
-
-
0025216220
-
Recombinant human bone morphogenetic protein induces bone formation
-
Wang E.A., Rosen V., D'Alessandro J.S., Bauduy M., Cordes P., Harada T., Israel D.I., Hewick R.M., Kerns K.M., LaPan P., Luxenberg D.P., Mcquaid D., Moutsatsos I.K., Nove J., Wozney J.M. Recombinant human bone morphogenetic protein induces bone formation. Proc. Natl. Acad. Sci. USA. 87:1990;2220-2224.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2220-2224
-
-
Wang, E.A.1
Rosen, V.2
D'Alessandro, J.S.3
Bauduy, M.4
Cordes, P.5
Harada, T.6
Israel, D.I.7
Hewick, R.M.8
Kerns, K.M.9
LaPan, P.10
Luxenberg, D.P.11
Mcquaid, D.12
Moutsatsos, I.K.13
Nove, J.14
Wozney, J.M.15
-
26
-
-
0037414760
-
The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2
-
Kim H.J., Kim J.H., Bae S.C., Choi J.Y., Kim H.J., Ryoo H.M. The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2. J. Biol. Chem. 278:2003;319-326.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 319-326
-
-
Kim, H.J.1
Kim, J.H.2
Bae, S.C.3
Choi, J.Y.4
Kim, H.J.5
Ryoo, H.M.6
|