Inhibition of the canonical Wnt pathway by high glucose can be reversed by parathyroid hormone-related protein in osteoblastic cells

Journal of Cellular Biochemistry

Volumn 114, Issue 8, 2013, Pages 1908-1916

  Lõpez Herradõn, Ana ^a   Portal Núñez, Sergio ^a   García Martín, Adela ^a   Lozano, Daniel ^a   Pérez Martínez, Francisco C ^b   Ceña, Valentín ^c,d   Esbrit, Pedro ^a  

^a INSTITUTO DE INVESTIGACIÓN SANITARIA DEL HOSPITAL CLÍNICO SAN CARLOS IDISSC   (Spain)

^b Unidad de Biomedicina UCLM CSIC Parque   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

CANONICAL Wnt PATHWAY; HIGH GLUCOSE; OSTEOBLASTS; PTHrP

Indexed keywords

BETA CATENIN; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; LOW DENSITY RECEPTOR LIKE PROTEIN 5; LOW DENSITY RECEPTOR LIKE PROTEIN 6; PARATHYROID HORMONE RELATED PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME SYNTHESIS; GENE EXPRESSION; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; UPREGULATION; WNT SIGNALING PATHWAY;

ANIMALS; ANTIMANIC AGENTS; BETA CATENIN; CELL LINE; GLUCOSE; HUMANS; LITHIUM CHLORIDE; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-5; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MICE; MUTATION; OSTEOBLASTS; OSTEOGENESIS; PARATHYROID HORMONE-RELATED PROTEIN; PROTEIN STABILITY; WNT SIGNALING PATHWAY; WNT3A PROTEIN;

MUS;

EID: 84879135061     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24535     Document Type: Article

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