Metformin reverses the deleterious effects of high glucose on osteoblast function

Journal of Diabetes and its Complications

Volumn 24, Issue 5, 2010, Pages 334-344

  Zhen, Donghu ^a   Chen, Yirong ^a   Tang, Xulei ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Diabetes mellitus; Glucose; Metformin; Osteoporosis; Primary Osteoblasts

Indexed keywords

ALKALINE PHOSPHATASE; ASCORBIC ACID; CALCIUM; COLLAGENASE; GLUCOSE; METFORMIN; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BONE DENSITY; BONE MINERALIZATION; CELL CULTURE; CELL FUNCTION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); DIABETES MELLITUS; GENE EXPRESSION; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; RAT;

ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; GLUCOSE; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN-LIKE GROWTH FACTOR I; METFORMIN; OSTEOBLASTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, IGF TYPE 1;

EID: 77956228665     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2009.05.002     Document Type: Article

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