Kurarinol induces hepatocellular carcinoma cell apoptosis through suppressing cellular signal transducer and activator of transcription 3 signaling

Toxicology and Applied Pharmacology

Volumn 281, Issue 2, 2014, Pages 157-165

  Shu, Guangwen ^a   Yang, Jing ^a   Zhao, Wenhao ^a   Xu, Chan ^a   Hong, Zongguo ^a   Mei, Zhinan ^a   Yang, Xinzhou ^a  

^a SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

Anti cancer; Apoptosis; Hepatocellular carcinoma; Kurarinol; Signal transduction; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; FLAVONOID; KURARINOL; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN; UNCLASSIFIED DRUG; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER TISSUE; CANCER TRANSPLANTATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG MECHANISM; GENETIC TRANSCRIPTION; HEPATOCELLULAR CARCINOMA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; ANIMAL; CARCINOMA, HEPATOCELLULAR; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; LIVER NEOPLASMS; METABOLISM; PATHOLOGY; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR BURDEN;

EID: 84912080093     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.021     Document Type: Article

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