Dominant-negative activity of the STAT3-Y705F mutant depends on the N-terminal domain

Cell Communication and Signaling

Volumn 11, Issue 1, 2013, Pages

  Mohr, Anne ^a   Fahrenkamp, Dirk ^a   Rinis, Natalie ^a   Müller Newen, Gerhard ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Dominant negative; Hyper IgE syndrome (HIES); IL 6; JAK STAT signaling; STAT3; STAT3 YF mutant

Indexed keywords

DNA; HETERODIMER; HOMODIMER; INTERLEUKIN 6; MUTANT PROTEIN; STAT3 PROTEIN; GLYCOPROTEIN GP 130; PHOSPHOTYROSINE; SOCS3 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA BINDING; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ACTIVE TRANSPORT; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; CYTOKINE RECEPTOR GP130; HUMANS; INTERLEUKIN-6; MUTATION; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84887045940     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-11-83     Document Type: Article

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