-
1
-
-
84890550726
-
RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications
-
Bernal J.A. RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications. J Cardiovasc Transl Res 2013, 6:956-968.
-
(2013)
J Cardiovasc Transl Res
, vol.6
, pp. 956-968
-
-
Bernal, J.A.1
-
3
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff J.A., Malone R.W., Williams P., Chong W., Acsadi G., Jani A., et al. Direct gene transfer into mouse muscle in vivo. Science 1990, 247:1465-1468.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
-
4
-
-
39349103969
-
Vaccination with Messenger RNA (mRNA)
-
Pascolo S. Vaccination with Messenger RNA (mRNA). Handb Exp Pharmacol 2008, 183:221-235.
-
(2008)
Handb Exp Pharmacol
, vol.183
, pp. 221-235
-
-
Pascolo, S.1
-
5
-
-
84866979353
-
MRNA as a versatile tool for exogenous protein expression
-
Kuhn A.N., Beiβert T., Simon P., Vallazza B., Buck J., Davies B.P., et al. mRNA as a versatile tool for exogenous protein expression. Curr Gene Ther 2012, 12:347-361.
-
(2012)
Curr Gene Ther
, vol.12
, pp. 347-361
-
-
Kuhn, A.N.1
Beiert, T.2
Simon, P.3
Vallazza, B.4
Buck, J.5
Davies, B.P.6
-
6
-
-
84870869040
-
Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection
-
Petsch B., Schnee M., Vogel A.B., Lange E., Hoffmann B., Voss D., et al. Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection. Nat Biotechnol 2012, 30:1210-1216.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 1210-1216
-
-
Petsch, B.1
Schnee, M.2
Vogel, A.B.3
Lange, E.4
Hoffmann, B.5
Voss, D.6
-
7
-
-
84878642106
-
Antitumor vaccination with synthetic mRNA: strategies for itro and ivo preclinical studies
-
Diken M., Kreiter S., Selmi A., Türeci O., Sahin U. Antitumor vaccination with synthetic mRNA: strategies for itro and ivo preclinical studies. Methods Mol Biol 2013, 969:235-246.
-
(2013)
Methods Mol Biol
, vol.969
, pp. 235-246
-
-
Diken, M.1
Kreiter, S.2
Selmi, A.3
Türeci, O.4
Sahin, U.5
-
8
-
-
84878635358
-
Synthetic mRNAs with superior translation and stability properties
-
Grudzien-Nogalska E., Kowalska J., Su W., Kuhn A.N., Slepenkov S.V., Darzynkiewicz E., et al. Synthetic mRNAs with superior translation and stability properties. Methods Mol Biol 2013, 969:55-72.
-
(2013)
Methods Mol Biol
, vol.969
, pp. 55-72
-
-
Grudzien-Nogalska, E.1
Kowalska, J.2
Su, W.3
Kuhn, A.N.4
Slepenkov, S.V.5
Darzynkiewicz, E.6
-
9
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L., Manos P.D., Ahfeldt T., Loh Y.H., Li H., Lau F., et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010, 7:618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
-
10
-
-
82255194361
-
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
-
Kariko K., Muramatsu H., Ludwig J., Weissman D. Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA. Nucleic Acids Res 2011, 39:e142.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. e142
-
-
Kariko, K.1
Muramatsu, H.2
Ludwig, J.3
Weissman, D.4
-
11
-
-
84879585559
-
Japan to offer fast-track approval path for stem cell therapies
-
Cyranoski D. Japan to offer fast-track approval path for stem cell therapies. Nat Med 2013, 19:510.
-
(2013)
Nat Med
, vol.19
, pp. 510
-
-
Cyranoski, D.1
-
12
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
13
-
-
34248672889
-
Antiviral signaling through pattern recognition receptors
-
Kawai T., Akira S. Antiviral signaling through pattern recognition receptors. J Biochem 2007, 141:137-145.
-
(2007)
J Biochem
, vol.141
, pp. 137-145
-
-
Kawai, T.1
Akira, S.2
-
14
-
-
48949094095
-
Structural mechanism of RNA recognition by the RIG-I-like receptors
-
Yoneyama M., Fujita T. Structural mechanism of RNA recognition by the RIG-I-like receptors. Immunity 2008, 29:178-181.
-
(2008)
Immunity
, vol.29
, pp. 178-181
-
-
Yoneyama, M.1
Fujita, T.2
-
15
-
-
77249132637
-
Recognition of viruses by cytoplasmic sensors
-
Wilkins C., Gale M. Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol 2010, 22:41-47.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 41-47
-
-
Wilkins, C.1
Gale, M.2
-
16
-
-
79551687500
-
Regulation of innate immunity through RNA structure and the protein kinase PKR
-
Nallagatla S.R., Toroney R., Bevilacqua P.C. Regulation of innate immunity through RNA structure and the protein kinase PKR. Curr Opin Struct Biol 2011, 21:119-127.
-
(2011)
Curr Opin Struct Biol
, vol.21
, pp. 119-127
-
-
Nallagatla, S.R.1
Toroney, R.2
Bevilacqua, P.C.3
-
18
-
-
77956384935
-
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination
-
Van Tendeloo V.F., Van de Velde A., Van Driessche A., Cools N., Anguille S., Ladell K., et al. Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination. Proc Natl Acad Sci USA 2010, 107:13824-13829.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13824-13829
-
-
Van Tendeloo, V.F.1
Van de Velde, A.2
Van Driessche, A.3
Cools, N.4
Anguille, S.5
Ladell, K.6
-
19
-
-
2942559009
-
Cancer immunotherapy with mRNA-transfected dendritic cells
-
Gilboa E., Vieweg J. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol Rev 2004, 199:251-263.
-
(2004)
Immunol Rev
, vol.199
, pp. 251-263
-
-
Gilboa, E.1
Vieweg, J.2
-
20
-
-
0027170483
-
Induction of virus-specific cytotoxic T lymphocytes ivo by liposome-entrapped mRNA
-
Martinon F., Krishnan S., Lenzen G., Magné R., Gomard E., Guillet J.G., et al. Induction of virus-specific cytotoxic T lymphocytes ivo by liposome-entrapped mRNA. Eur J Immunol 1993, 23:1719-1722.
-
(1993)
Eur J Immunol
, vol.23
, pp. 1719-1722
-
-
Martinon, F.1
Krishnan, S.2
Lenzen, G.3
Magné, R.4
Gomard, E.5
Guillet, J.G.6
-
21
-
-
84857045791
-
MRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
-
Van Gulck E., Vlieghe E., Vekemans M., Van Tendeloo V.F., Van De Velde A., Smits E., et al. mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients. AIDS 2012, 26:F1-F12.
-
(2012)
AIDS
, vol.26
, pp. F1-F12
-
-
Van Gulck, E.1
Vlieghe, E.2
Vekemans, M.3
Van Tendeloo, V.F.4
Van De Velde, A.5
Smits, E.6
-
22
-
-
84864953127
-
Interleukin-12p70 expression by dendritic cells of HIV-1-infected patients fails to stimulate gag-specific immune responses
-
Van Gulck E., Cools N., Atkinson D., Bracke L., Vereecken K., Vekemans M., et al. Interleukin-12p70 expression by dendritic cells of HIV-1-infected patients fails to stimulate gag-specific immune responses. Clin Dev Immunol 2012, 10.1155/2012/184979.
-
(2012)
Clin Dev Immunol
-
-
Van Gulck, E.1
Cools, N.2
Atkinson, D.3
Bracke, L.4
Vereecken, K.5
Vekemans, M.6
-
23
-
-
83155183302
-
MRNA vaccination as a safe approach for specific protection from type I allergy
-
Weiss R., Scheiblhofer S., Roesler E., Weinberger E., Thalhamer J. mRNA vaccination as a safe approach for specific protection from type I allergy. Expert Rev Vaccines 2012, 11:55-67.
-
(2012)
Expert Rev Vaccines
, vol.11
, pp. 55-67
-
-
Weiss, R.1
Scheiblhofer, S.2
Roesler, E.3
Weinberger, E.4
Thalhamer, J.5
-
24
-
-
23844464444
-
Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA
-
Kariko K., Buckstein M., Ni H., Weissman D. Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA. Immunity 2005, 23:165-175.
-
(2005)
Immunity
, vol.23
, pp. 165-175
-
-
Kariko, K.1
Buckstein, M.2
Ni, H.3
Weissman, D.4
-
25
-
-
54949112814
-
Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability
-
Kariko K., Muramatsu H., Welsh F.A., Ludwig J., Kato H., Akira S., et al. Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. Mol Ther 2008, 16:1833-1840.
-
(2008)
Mol Ther
, vol.16
, pp. 1833-1840
-
-
Kariko, K.1
Muramatsu, H.2
Welsh, F.A.3
Ludwig, J.4
Kato, H.5
Akira, S.6
-
26
-
-
44149112583
-
Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner
-
Nallagatla S.R., Bevilacqua P.C. Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner. RNA 2008, 14:1201-1213.
-
(2008)
RNA
, vol.14
, pp. 1201-1213
-
-
Nallagatla, S.R.1
Bevilacqua, P.C.2
-
27
-
-
66149114745
-
Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities
-
Uzri D., Gehrke L. Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities. J Virol 2009, 83:4174-4184.
-
(2009)
J Virol
, vol.83
, pp. 4174-4184
-
-
Uzri, D.1
Gehrke, L.2
-
28
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V., Ellegast J., Kim S., Brzózka K., Jung A., Kato H., et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006, 314:994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzózka, K.4
Jung, A.5
Kato, H.6
-
29
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A., Schulz O., Tan C.P., Näslund T.I., Liljeström P., Weber F., et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006, 314:997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Näslund, T.I.4
Liljeström, P.5
Weber, F.6
-
30
-
-
84875160871
-
Reprogramming human fibroblast to pluripotency using modified mRNA
-
Mandal P.K., Rossi D.J. Reprogramming human fibroblast to pluripotency using modified mRNA. Nat Protoc 2013, 8:568-582.
-
(2013)
Nat Protoc
, vol.8
, pp. 568-582
-
-
Mandal, P.K.1
Rossi, D.J.2
-
31
-
-
0001207805
-
UAG read through during TMV RNA translation: isolation and sequence of two tRNAs with suppressor activity from tobacco plants
-
Beier H., Barciszewska M., Krupp G., Mitnacht R., Gross H.J. UAG read through during TMV RNA translation: isolation and sequence of two tRNAs with suppressor activity from tobacco plants. EMBO J 1984, 3:351-356.
-
(1984)
EMBO J
, vol.3
, pp. 351-356
-
-
Beier, H.1
Barciszewska, M.2
Krupp, G.3
Mitnacht, R.4
Gross, H.J.5
-
32
-
-
84881155082
-
Efficient generation of human iPSCs by synthetic self-replicative RNA
-
Yoshioka N., Gros E., Li H.R., Kumar S., Deacon D.C., Maron C., et al. Efficient generation of human iPSCs by synthetic self-replicative RNA. Cell Stem Cell 2013, 13:246-254.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 246-254
-
-
Yoshioka, N.1
Gros, E.2
Li, H.R.3
Kumar, S.4
Deacon, D.C.5
Maron, C.6
-
33
-
-
79955054845
-
MRNA as gene therapeutic: how to control protein expression
-
Tavernier G., Andries O., Demeester J., Sanders N.N., De Smedt S.C., Rejman J. mRNA as gene therapeutic: how to control protein expression. J Control Release 2011, 150:238-247.
-
(2011)
J Control Release
, vol.150
, pp. 238-247
-
-
Tavernier, G.1
Andries, O.2
Demeester, J.3
Sanders, N.N.4
De Smedt, S.C.5
Rejman, J.6
-
34
-
-
79751497093
-
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
-
Kormann M., Hasenpusch G., Aneja M.K., Nica G., Flemmer A.W., Herber-Jonat S., et al. Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nat Biotechnol 2011, 29:154-157.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 154-157
-
-
Kormann, M.1
Hasenpusch, G.2
Aneja, M.K.3
Nica, G.4
Flemmer, A.W.5
Herber-Jonat, S.6
-
36
-
-
84860539841
-
Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin
-
Kariko K., Muramatsu H., Keller J.M., Weissman D. Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin. Mol Ther 2012, 20:948-953.
-
(2012)
Mol Ther
, vol.20
, pp. 948-953
-
-
Kariko, K.1
Muramatsu, H.2
Keller, J.M.3
Weissman, D.4
|