Synthetic mRNAs with superior translation and stability properties

Methods in Molecular Biology

Volumn 969, Issue , 2013, Pages 55-72

  Grudzien Nogalska, Ewa ^a   Kowalska, Joanna ^b   Su, Wei ^a   Kuhn, Andreas N ^c,d   Slepenkov, Sergey V ^a   Darzynkiewicz, Edward ^b   Sahin, Ugur ^c,d,e   Jemielity, Jacek ^b   Rhoads, Robert E ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF WARSAW   (Poland)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^d BIONTECH AG   (Germany)

^e JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Boranophosphate; Cap analogs; Decapping; Gene therapy; Immunotherapy; MRNA stability; Nucleoporation; Phosphorothioate; Protein expression; Translational efficiency

Indexed keywords

CAPPED RNA; MESSENGER RNA;

ANIMAL; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HUMAN; METHODOLOGY; PROTEIN SYNTHESIS; REVIEW; RNA STABILITY; SYNTHESIS;

ANIMALS; HUMANS; PROTEIN BIOSYNTHESIS; RNA CAP ANALOGS; RNA STABILITY; RNA, MESSENGER; TRANSFECTION;

MLCS; MLOWN;

EID: 84878635358     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-260-5_4     Document Type: Article

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