메뉴 건너뛰기




Volumn 74, Issue , 2015, Pages 58-65

Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study

Author keywords

Microglia; Mild traumatic brain injury; Molecular neuroimaging; Neuroinflammation; Translocator protein

Indexed keywords

CARRIER PROTEIN; DPA 713 C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; ACETAMIDE DERIVATIVE; CARBON; N,N-DIETHYL-2-(2-(4-METHOXYPHENYL)-5,7-DIMETHYL-PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-ACETAMIDE; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

EID: 84912003698     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.10.019     Document Type: Article
Times cited : (197)

References (52)
  • 1
    • 34248529814 scopus 로고    scopus 로고
    • 11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation
    • Boutin H., et al. 11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation. J Nucl Med 2007, 48:573-581.
    • (2007) J Nucl Med , vol.48 , pp. 573-581
    • Boutin, H.1
  • 2
    • 84871650203 scopus 로고    scopus 로고
    • Neuroinflammation and neurodegeneration in overnutrition-induced diseases
    • Cai D. Neuroinflammation and neurodegeneration in overnutrition-induced diseases. Trends Endocrinol Metab 2013, 24:40-47.
    • (2013) Trends Endocrinol Metab , vol.24 , pp. 40-47
    • Cai, D.1
  • 3
    • 58149303036 scopus 로고    scopus 로고
    • Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers
    • Chauveau F., et al. Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers. Eur J Nucl Med Mol Imaging 2008, 35:2304-2319.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 2304-2319
    • Chauveau, F.1
  • 4
    • 84887230291 scopus 로고    scopus 로고
    • Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808
    • Chien D.T., et al. Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. J Alzheimers Dis 2014, 38:171-184.
    • (2014) J Alzheimers Dis , vol.38 , pp. 171-184
    • Chien, D.T.1
  • 5
    • 0033536463 scopus 로고    scopus 로고
    • Relationship between concussion and neuropsychological performance in college football players
    • Collins M.W., et al. Relationship between concussion and neuropsychological performance in college football players. JAMA 1999, 282:964-970.
    • (1999) JAMA , vol.282 , pp. 964-970
    • Collins, M.W.1
  • 6
    • 84905407732 scopus 로고    scopus 로고
    • Regional brain distribution of translocator protein using [C]DPA-713 PET in individuals infected with HIV
    • Coughlin J.M., et al. Regional brain distribution of translocator protein using [C]DPA-713 PET in individuals infected with HIV. J Neurovirol. 2014, 20:219-232.
    • (2014) J Neurovirol. , vol.20 , pp. 219-232
    • Coughlin, J.M.1
  • 7
    • 27744559053 scopus 로고    scopus 로고
    • Recall discriminability: utility of a new CVLT-II measure in the differential diagnosis of dementia
    • Delis D.C., et al. Recall discriminability: utility of a new CVLT-II measure in the differential diagnosis of dementia. J Int Neuropsychol Soc 2005, 11:708-715.
    • (2005) J Int Neuropsychol Soc , vol.11 , pp. 708-715
    • Delis, D.C.1
  • 8
    • 0029825190 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptors: molecular pharmacology to possible physiological significance in stress-induced hypertension
    • Drugan R.C. Peripheral benzodiazepine receptors: molecular pharmacology to possible physiological significance in stress-induced hypertension. Clin Neuropharmacol 1996, 19:475-496.
    • (1996) Clin Neuropharmacol , vol.19 , pp. 475-496
    • Drugan, R.C.1
  • 9
    • 70749093164 scopus 로고    scopus 로고
    • Differential effects of global and cerebellar normalization on detection and differentiation of dementia in FDG-PET studies
    • Dukart J., et al. Differential effects of global and cerebellar normalization on detection and differentiation of dementia in FDG-PET studies. Neuroimage 2010, 49:1490-1495.
    • (2010) Neuroimage , vol.49 , pp. 1490-1495
    • Dukart, J.1
  • 10
    • 68249150559 scopus 로고    scopus 로고
    • Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans
    • Endres C.J., et al. Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans. J Nucl Med 2009, 50:1276-1282.
    • (2009) J Nucl Med , vol.50 , pp. 1276-1282
    • Endres, C.J.1
  • 11
    • 84868032865 scopus 로고    scopus 로고
    • A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology
    • Erlandsson K., et al. A review of partial volume correction techniques for emission tomography and their applications in neurology, cardiology and oncology. Phys Med Biol 2012, 57:R119-R159.
    • (2012) Phys Med Biol , vol.57 , pp. R119-R159
    • Erlandsson, K.1
  • 12
    • 18244406829 scopus 로고    scopus 로고
    • Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain
    • Fischl B., et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002, 33:341-355.
    • (2002) Neuron , vol.33 , pp. 341-355
    • Fischl, B.1
  • 13
    • 80051686896 scopus 로고    scopus 로고
    • Widespread and prolonged increase in (R)-(11)C-PK11195 binding after traumatic brain injury
    • Folkersma H., et al. Widespread and prolonged increase in (R)-(11)C-PK11195 binding after traumatic brain injury. J Nucl Med 2011, 52:1235-1239.
    • (2011) J Nucl Med , vol.52 , pp. 1235-1239
    • Folkersma, H.1
  • 14
    • 84885620053 scopus 로고    scopus 로고
    • Episodic memory in former professional football players with a history of concussion: an event-related functional neuroimaging study
    • Ford J.H., et al. Episodic memory in former professional football players with a history of concussion: an event-related functional neuroimaging study. J Neurotrauma 2013, 30:1683-1701.
    • (2013) J Neurotrauma , vol.30 , pp. 1683-1701
    • Ford, J.H.1
  • 15
    • 0023722018 scopus 로고
    • Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images
    • Fox P.T., et al. Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images. J Cereb Blood Flow Metab 1988, 8:642-653.
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 642-653
    • Fox, P.T.1
  • 16
    • 0032707529 scopus 로고    scopus 로고
    • Enigma of the peripheral benzodiazepine receptor
    • Gavish M., et al. Enigma of the peripheral benzodiazepine receptor. Pharmacol Rev 1999, 51:629-650.
    • (1999) Pharmacol Rev , vol.51 , pp. 629-650
    • Gavish, M.1
  • 17
    • 33745925898 scopus 로고    scopus 로고
    • Association between recurrent concussion and late-life cognitive impairment in retired professional football players
    • (discussion 719-726)
    • Guskiewicz K.M., et al. Association between recurrent concussion and late-life cognitive impairment in retired professional football players. Neurosurgery 2005, 57:719-726. (discussion 719-726).
    • (2005) Neurosurgery , vol.57 , pp. 719-726
    • Guskiewicz, K.M.1
  • 18
    • 34249999673 scopus 로고    scopus 로고
    • Recurrent concussion and risk of depression in retired professional football players
    • Guskiewicz K.M., et al. Recurrent concussion and risk of depression in retired professional football players. Med Sci Sports Exerc 2007, 39:903-909.
    • (2007) Med Sci Sports Exerc , vol.39 , pp. 903-909
    • Guskiewicz, K.M.1
  • 20
    • 84874913446 scopus 로고    scopus 로고
    • Neuroimaging of cognitive dysfunction and depression in aging retired National Football League players: a cross-sectional study
    • Hart J., et al. Neuroimaging of cognitive dysfunction and depression in aging retired National Football League players: a cross-sectional study. JAMA Neurol 2013, 70:326-335.
    • (2013) JAMA Neurol , vol.70 , pp. 326-335
    • Hart, J.1
  • 21
    • 84890448682 scopus 로고    scopus 로고
    • Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology
    • Hazrati L.N., et al. Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology. Front Hum Neurosci 2013, 7:222.
    • (2013) Front Hum Neurosci , vol.7 , pp. 222
    • Hazrati, L.N.1
  • 22
    • 2542509442 scopus 로고    scopus 로고
    • Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists
    • Hellstrom-Lindahl E., et al. Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists. J Neurochem 2000, 74:777-784.
    • (2000) J Neurochem , vol.74 , pp. 777-784
    • Hellstrom-Lindahl, E.1
  • 23
    • 34547846251 scopus 로고    scopus 로고
    • Consensus nomenclature for in vivo imaging of reversibly binding radioligands
    • Innis R.B., et al. Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab 2007, 27:1533-1539.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1533-1539
    • Innis, R.B.1
  • 24
    • 84877577409 scopus 로고    scopus 로고
    • The clinical spectrum of sport-related traumatic brain injury
    • Jordan B.D. The clinical spectrum of sport-related traumatic brain injury. Nat Rev Neurol 2013, 9:222-230.
    • (2013) Nat Rev Neurol , vol.9 , pp. 222-230
    • Jordan, B.D.1
  • 25
    • 0029166124 scopus 로고
    • The Rivermead Post Concussion Symptoms Questionnaire: a measure of symptoms commonly experienced after head injury and its reliability
    • King N.S., et al. The Rivermead Post Concussion Symptoms Questionnaire: a measure of symptoms commonly experienced after head injury and its reliability. J Neurol 1995, 242:587-592.
    • (1995) J Neurol , vol.242 , pp. 587-592
    • King, N.S.1
  • 26
    • 84871920442 scopus 로고    scopus 로고
    • A genetic polymorphism for translocator protein 18kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation
    • Kreisl W.C., et al. A genetic polymorphism for translocator protein 18kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation. J Cereb Blood Flow Metab 2013, 33:53-58.
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 53-58
    • Kreisl, W.C.1
  • 27
    • 84879901761 scopus 로고    scopus 로고
    • In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease
    • Kreisl W.C., et al. In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease. Brain 2013, 136:2228-2238.
    • (2013) Brain , vol.136 , pp. 2228-2238
    • Kreisl, W.C.1
  • 28
    • 84869846083 scopus 로고    scopus 로고
    • Neurodegenerative causes of death among retired National Football League players
    • Lehman E.J., et al. Neurodegenerative causes of death among retired National Football League players. Neurology 2012, 79:1970-1974.
    • (2012) Neurology , vol.79 , pp. 1970-1974
    • Lehman, E.J.1
  • 29
    • 0025127930 scopus 로고
    • Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects
    • Logan J., et al. Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects. J Cereb Blood Flow Metab 1990, 10:740-747.
    • (1990) J Cereb Blood Flow Metab , vol.10 , pp. 740-747
    • Logan, J.1
  • 30
    • 0033536479 scopus 로고    scopus 로고
    • Neuropsychological impairment in amateur soccer players
    • Matser E.J., et al. Neuropsychological impairment in amateur soccer players. JAMA 1999, 282:971-973.
    • (1999) JAMA , vol.282 , pp. 971-973
    • Matser, E.J.1
  • 31
    • 84863620827 scopus 로고    scopus 로고
    • Cognitive effects of one season of head impacts in a cohort of collegiate contact sport athletes
    • McAllister T.W., et al. Cognitive effects of one season of head impacts in a cohort of collegiate contact sport athletes. Neurology 2012, 78:1777-1784.
    • (2012) Neurology , vol.78 , pp. 1777-1784
    • McAllister, T.W.1
  • 32
    • 84892150314 scopus 로고    scopus 로고
    • Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes
    • McAllister T.W., et al. Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes. Neurology 2014, 82:63-69.
    • (2014) Neurology , vol.82 , pp. 63-69
    • McAllister, T.W.1
  • 33
    • 84873352895 scopus 로고    scopus 로고
    • The spectrum of disease in chronic traumatic encephalopathy
    • McKee A.C., et al. The spectrum of disease in chronic traumatic encephalopathy. Brain 2013, 136:43-64.
    • (2013) Brain , vol.136 , pp. 43-64
    • McKee, A.C.1
  • 34
    • 84892672872 scopus 로고    scopus 로고
    • The neuropathology of sport
    • McKee A.C., et al. The neuropathology of sport. Acta Neuropathol 2014, 127:29-51.
    • (2014) Acta Neuropathol , vol.127 , pp. 29-51
    • McKee, A.C.1
  • 35
    • 84908651577 scopus 로고    scopus 로고
    • Obesity and neuroinflammation: a pathway to cognitive impairment
    • Miller A.A., Spencer S.J. Obesity and neuroinflammation: a pathway to cognitive impairment. Brain Behav Immun. 2014, 42:10-21.
    • (2014) Brain Behav Immun. , vol.42 , pp. 10-21
    • Miller, A.A.1    Spencer, S.J.2
  • 36
    • 84861846497 scopus 로고    scopus 로고
    • Translocator protein (18kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA
    • Mizrahi R., et al. Translocator protein (18kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA. J Cereb Blood Flow Metab 2012, 32:968-972.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 968-972
    • Mizrahi, R.1
  • 37
    • 84855340957 scopus 로고    scopus 로고
    • An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28
    • Owen D.R., et al. An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28. J Cereb Blood Flow Metab 2012, 32:1-5.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1-5
    • Owen, D.R.1
  • 38
    • 68749119440 scopus 로고    scopus 로고
    • Translocator protein (18kDa) TSPO: an emerging therapeutic target in neurotrauma
    • Papadopoulos V., Lecanu L. Translocator protein (18kDa) TSPO: an emerging therapeutic target in neurotrauma. Exp Neurol 2009, 219:53-57.
    • (2009) Exp Neurol , vol.219 , pp. 53-57
    • Papadopoulos, V.1    Lecanu, L.2
  • 39
    • 33746035655 scopus 로고    scopus 로고
    • Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function
    • Papadopoulos V., et al. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol Sci 2006, 27:402-409.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 402-409
    • Papadopoulos, V.1
  • 40
    • 84903846151 scopus 로고    scopus 로고
    • The long-term effects of sports concussion on retired Australian football players: a study using transcranial magnetic stimulation
    • Pearce A.J., et al. The long-term effects of sports concussion on retired Australian football players: a study using transcranial magnetic stimulation. J Neurotrauma 2014, 31:1139-1145.
    • (2014) J Neurotrauma , vol.31 , pp. 1139-1145
    • Pearce, A.J.1
  • 41
    • 4644340219 scopus 로고    scopus 로고
    • Statistical list-mode image reconstruction for the high resolution research tomograph
    • Rahmim A., et al. Statistical list-mode image reconstruction for the high resolution research tomograph. Phys Med Biol 2004, 49:4239-4258.
    • (2004) Phys Med Biol , vol.49 , pp. 4239-4258
    • Rahmim, A.1
  • 42
    • 80052585240 scopus 로고    scopus 로고
    • Inflammation after trauma: microglial activation and traumatic brain injury
    • Ramlackhansingh A.F., et al. Inflammation after trauma: microglial activation and traumatic brain injury. Ann Neurol 2011, 70:374-383.
    • (2011) Ann Neurol , vol.70 , pp. 374-383
    • Ramlackhansingh, A.F.1
  • 43
    • 33744794655 scopus 로고    scopus 로고
    • Acetylcholine receptors and tau phosphorylation
    • Rubio A., et al. Acetylcholine receptors and tau phosphorylation. Curr Mol Med 2006, 6:423-428.
    • (2006) Curr Mol Med , vol.6 , pp. 423-428
    • Rubio, A.1
  • 44
    • 84880346238 scopus 로고    scopus 로고
    • Profile of self-reported problems with executive functioning in college and professional football players
    • Seichepine D.R., et al. Profile of self-reported problems with executive functioning in college and professional football players. J Neurotrauma 2013, 30:1299-1304.
    • (2013) J Neurotrauma , vol.30 , pp. 1299-1304
    • Seichepine, D.R.1
  • 45
    • 84867358425 scopus 로고    scopus 로고
    • Dementia resulting from traumatic brain injury: what is the pathology?
    • Shively S., et al. Dementia resulting from traumatic brain injury: what is the pathology?. Arch Neurol 2012, 69:1245-1251.
    • (2012) Arch Neurol , vol.69 , pp. 1245-1251
    • Shively, S.1
  • 46
    • 84900303891 scopus 로고    scopus 로고
    • Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes
    • Singh R., et al. Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes. JAMA 2014, 311:1883-1888.
    • (2014) JAMA , vol.311 , pp. 1883-1888
    • Singh, R.1
  • 47
    • 84875442334 scopus 로고    scopus 로고
    • PET scanning of brain tau in retired national football league players: preliminary findings
    • Small G.W., et al. PET scanning of brain tau in retired national football league players: preliminary findings. Am J Geriatr Psychiatry 2013, 21:138-144.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 138-144
    • Small, G.W.1
  • 48
    • 84877584268 scopus 로고    scopus 로고
    • Chronic neuropathologies of single and repetitive TBI: substrates of dementia?
    • Smith D.H., et al. Chronic neuropathologies of single and repetitive TBI: substrates of dementia?. Nat Rev Neurol 2013, 9:211-221.
    • (2013) Nat Rev Neurol , vol.9 , pp. 211-221
    • Smith, D.H.1
  • 49
    • 84892718392 scopus 로고    scopus 로고
    • Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel
    • Stein T.D., et al. Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel. Alzheimers Res Ther 2014, 6:4.
    • (2014) Alzheimers Res Ther , vol.6 , pp. 4
    • Stein, T.D.1
  • 50
    • 0030937756 scopus 로고    scopus 로고
    • Practice parameter: the management of concussion in sports (summary statement). Report of the Quality Standards Subcommittee
    • The Quality Standards Subcommittee Practice parameter: the management of concussion in sports (summary statement). Report of the Quality Standards Subcommittee. Neurology 1997, 48:581-585.
    • (1997) Neurology , vol.48 , pp. 581-585
  • 51
    • 33644928715 scopus 로고    scopus 로고
    • Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate
    • Thominiaux C., et al. Improved synthesis of the peripheral benzodiazepine receptor ligand [11C]DPA-713 using [11C]methyl triflate. Appl Radiat Isot 2006, 64:570-573.
    • (2006) Appl Radiat Isot , vol.64 , pp. 570-573
    • Thominiaux, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.