Dementia resulting from traumatic brain injury: What is the pathology?

Archives of Neurology

Volumn 69, Issue 10, 2012, Pages 1245-1251

  Shively, Sharon ^a   Scher, Ann I ^a,b   Perl, Daniel P ^a   Diaz Arrastia, Ramon ^a,b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN;

CLINICAL FEATURE; DEGENERATIVE DISEASE; DEMENTIA; DISEASE SEVERITY; GENE LINKAGE DISEQUILIBRIUM; HISTOPATHOLOGY; HUMAN; INCIDENCE; NEUROLOGIC EXAMINATION; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; REVIEW; RISK FACTOR; TRAUMATIC BRAIN INJURY; UNCONSCIOUSNESS; UPREGULATION; VETERAN;

BRAIN INJURIES; COMBAT DISORDERS; DEMENTIA; HUMANS; NEURODEGENERATIVE DISEASES; RISK FACTORS;

EID: 84867358425     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneurol.2011.3747     Document Type: Review

References (50)

1. Finger S. Origins of Neuroscience: A History of Explorations Into Brain Function. New York, NY: Oxford University Press; 1994.
2. Dart RA. The predatory implemental technique of Australopithecus. Am J Phys Anthropol. 1949;7(1):1-38.
3. Tung TA. Trauma and violence in the Wari empire of the Peruvian Andes: warfare, raids, and ritual fights. Am J Phys Anthropol. 2007;133(3):941-956. (Pubitemid 46919574)
4. Torres-Rouff C, Costa Junqueira MA. Interpersonal violence in prehistoric San Pedro de Atacama, Chile: behavioral implications of environmental stress. Am J Phys Anthropol. 2006;130(1):60-70.
5. Faul M, Xu L, Wald MW, Coronado VG. Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations, and Deaths 2002-2006. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control; 2010.
6. Thurman DJ, Coronado V, Selassie A. The epidemiology of TBI: implications for public health. In: Zasler ND, Katz DI, Zafonte RD, eds. Brain Injury Medicine: Principles and Practice. New York, NY: Demos; 2007:45-55.
7. Thurman DJ, Alverson C, Dunn KA, Guerrero J, Sniezek JE. Traumatic brain injury in the United States: a public health perspective. J Head Trauma Rehabil. 1999;14(6):602-615. (Pubitemid 30027268)
8. Fleminger S, Oliver DL, Lovestone S, Rabe-Hesketh S, Giora A. Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on. a partial replication. J Neurol Neurosurg Psychiatry. 2003;74(7):857-862. (Pubitemid 36782983)
9. Guo Z, Cupples LA, Kurz A, et al. Head injury and the risk of AD in the MIRAGE study. Neurology. 2000;54(6):1316-1323. (Pubitemid 30174053)
10. Plassman BL, Havlik RJ, Steffens DC, et al. Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias. Neurology. 2000;55(8):1158-1166.
11. Institute of Medicine Committee on Gulf War and Health. Gulf War and Health, Volume 7: Long-Term Consequences of Traumatic Brain Injury. Washington, DC: National Academies Press; 2009.
12. McKinlay A, Grace RC, Horwood LJ, Fergusson DM, Ridder EM, MacFarlane MR. Prevalence of traumatic brain injury among children, adolescents and young adults: prospective evidence from a birth cohort. Brain Inj. 2008;22(2):175-181. (Pubitemid 351233926)
13. Kahn HA, Sempos CT. Attributable Risk: Statistical Methods in Epidemiology. New York, NY: Oxford University Press; 1989:72-84.
14. Mayeux R, Ottman R, Maestre G, et al. Synergistic effects of traumatic head injury and apolipoprotein-ε 4 in patients with Alzheimer's disease. Neurology. 1995;45(3, pt 1):555-557.
15. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939-944. (Pubitemid 14076461)
16. Smith DH, Chen XH, Pierce JE, et al. Progressive atrophy and neuron death for one year following brain trauma in the rat. J Neurotrauma. 1997;14(10):715-727. (Pubitemid 27479412)
17. Bramlett HM, Dietrich WD. Quantitative structural changes in white and gray matter 1 year following traumatic brain injury in rats. Acta Neuropathol. 2002;103(6):607-614. (Pubitemid 36067509)
18. Iwata A, Chen XH, McIntosh TK, Browne KD, Smith DH. Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. J Neuropathol Exp Neurol. 2002;61(12):1056-1068. (Pubitemid 35435024)
19. Chen XH, Siman R, Iwata A, Meaney DF, Trojanowski JQ, Smith DH. Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma. Am J Pathol. 2004;165(2):357-371. (Pubitemid 38971368)
20. Uryu K, Laurer H, McIntosh T, et al. Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis. J Neurosci. 2002;22(2):446-454. (Pubitemid 34049082)
21. Tran HT, LaFerla FM, Holtzman DM, Brody DL. Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities. J Neurosci. 2011;31(26):9513-9525.
22. Johnson VE, Stewart W, Smith DH. Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease? Nat Rev Neurosci . 2010;11(5):361-370.
23. Loane DJ, Pocivavsek A, Moussa CE, et al. Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med. 2009;15(4):377-379.
24. Biran Y, Masters CL, Barnham KJ, Bush AI, Adlard PA. Pharmacotherapeutic targets in Alzheimer's disease. J Cell Mol Med. 2009;13(1):61-86.
25. Roberts GW, Gentleman SM, Lynch A, Murray L, Landon M, Graham DI. Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1994;57(4):419-425.
26. Ikonomovic MD, Uryu K, Abrahamson EE, et al. Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury. Exp Neurol. 2004;190(1):192-203. (Pubitemid 39335718)
27. DeKosky ST, Abrahamson EE, Ciallella JR, et al. Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans. Arch Neurol. 2007;64(4):541-544. (Pubitemid 46588343)
28. Johnson VE, Stewart W, Smith DH. Widespread tau and amyloid-Beta pathology many years after a single traumatic brain injury in humans. Brain Pathol. 2012;22(2):142-149.
29. McKee AC, Cantu RC, Nowinski CJ, et al. Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol. 2009;68(7):709-735.
30. Warner MA, Youn TS, Davis T, et al. Regionally selective atrophy after traumatic axonal injury. Arch Neurol. 2010;67(11):1336-1344.
31. Buckner RL, Sepulcre J, Talukdar T, et al. Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. J Neurosci. 2009;29(6):1860-1873.
32. Martland H. Dementia pugilistica. JAMA. 1928;91:1103-1107.
33. Roberts AH. Brain Damage in Boxers: A Study of the Prevalence of Traumatic Encephalopathy Among Ex-Professional Boxers. London, England: Pitman Medical and Scientific Publishing; 1969.
34. Jordan BD. Chronic traumatic brain injury associated with boxing. Semin Neurol. 2000;20(2):179-185. (Pubitemid 30483028)
35. Jordan BD, Relkin NR, Ravdin LD, Jacobs AR, Bennett A, Gandy S. Apolipoprotein E ε4 associated with chronic traumatic brain injury in boxing. JAMA. 1997;278(2):136-140. (Pubitemid 27287671)
36. Corsellis JA, Bruton CJ, Freeman-Browne D. The aftermath of boxing. Psychol Med. 1973;3(3):270-303.
37. McKee AC, Gavett BE, Stern RA, et al. TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2010;69(9):918-929.
38. Hof PR, Bouras C, Buée L, Delacourte A, Perl DP, Morrison JH. Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol. 1992;85(1):23-30.
39. Mott FW. The effects of high explosives upon the central nervous system, II. Lancet. 1916;4826:441-449.
40. Mott FW. The effects of high explosives upon the central nervous system, III. Lancet. 1916;4828:545-553.
41. Scarborough L. Report of the War Office Committee of Enquiry Into "Shell Shock". London, England: HMSO; 1922.
42. Jordan BK, Schlenger WE, Hough R, et al. Lifetime and current prevalence of specific psychiatric disorders among Vietnam veterans and controls. Arch Gen Psychiatry. 1991;48(3):207-215.
43. Spiro A III, Schnurr PP, Aldwin CM. Combat-related posttraumatic stress disorder symptoms in older men. Psychol Aging. 1994;9(1):17-26. (Pubitemid 24281667)
44. Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL. Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care. N Engl J Med. 2004;351(1):13-22. (Pubitemid 38857243)
45. Hoge CW, McGurk D, Thomas JL, Cox AL, Engel CC, Castro CA. Mild traumatic brain injury in U.S. soldiers returning from Iraq. N Engl J Med. 2008;358(5): 453-463. (Pubitemid 351185801)
46. Ruff RL, Ruff SS, Wang X-F. Neurological deficits and post-traumatic stress disorder (PTSD) are related to the number of episodes of mild traumatic brain injury in US combat veterans [abstract]. Neurology. 2011;76:A161.
47. Yaffe K, Vittinghoff E, Lindquist K, et al. Posttraumatic stress disorder and risk of dementia among US veterans. Arch Gen Psychiatry. 2010;67(6):608-613.
48. Omalu B, Hammers JL, Bailes J, et al. Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide. Neurosurg Focus. 2011;31(5):E3.
49. Savonenko AV, Melnikova T, Hiatt A, et al. Alzheimer's therapeutics: translation of preclinical science to clinical drug development. Neuropsychopharmacology. 2012;37(1):261-277.
50. Jack CR Jr, Vemuri P, Wiste HJ, et al. Alzheimer's Disease Neuroimaging Initiative. Evidence for ordering of Alzheimer disease biomarkers. Arch Neurol. 2011;68(12):1526-1535.