Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17

Journal of Physiology

Volumn 592, Issue 20, 2014, Pages 4507-4521

  Otulakowski, Gail ^a   Engelberts, Doreen ^a   Gusarova, Galina A ^b   Bhattacharya, Jahar ^b   Post, Martin ^a   Kavanagh, Brian P ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISINTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MATRIX METALLOPROTEINASE 17; MATRIX METALLOPROTEINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ADAM PROTEIN; ADAM17 PROTEIN, MOUSE; ADAM17 PROTEIN, RAT; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HYPERCAPNIA; IN VIVO STUDY; LIGAND BINDING; LUNG ALVEOLUS EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VENTILATOR INDUCED LUNG INJURY; ACIDOSIS; ANIMAL; C57BL MOUSE; EPITHELIUM CELL; GENETICS; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACIDOSIS; ADAM PROTEINS; ADAM17 PROTEIN; ANIMALS; CELLS, CULTURED; EPITHELIAL CELLS; HYPERCAPNIA; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; VENTILATOR-INDUCED LUNG INJURY;

EID: 84911993148     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.277616     Document Type: Article

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